Download or read book Opioids in South Africa written by Thembisa Waetjen and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Pain Management and the Opioid Epidemic written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-09-28 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.
Download or read book Medications for Opioid Use Disorder Save Lives written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2019-06-16 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt: The opioid crisis in the United States has come about because of excessive use of these drugs for both legal and illicit purposes and unprecedented levels of consequent opioid use disorder (OUD). More than 2 million people in the United States are estimated to have OUD, which is caused by prolonged use of prescription opioids, heroin, or other illicit opioids. OUD is a life-threatening condition associated with a 20-fold greater risk of early death due to overdose, infectious diseases, trauma, and suicide. Mortality related to OUD continues to escalate as this public health crisis gathers momentum across the country, with opioid overdoses killing more than 47,000 people in 2017 in the United States. Efforts to date have made no real headway in stemming this crisis, in large part because tools that already existâ€"like evidence-based medicationsâ€"are not being deployed to maximum impact. To support the dissemination of accurate patient-focused information about treatments for addiction, and to help provide scientific solutions to the current opioid crisis, this report studies the evidence base on medication assisted treatment (MAT) for OUD. It examines available evidence on the range of parameters and circumstances in which MAT can be effectively delivered and identifies additional research needed.
Download or read book Guidelines for the Psychosocially Assisted Pharmacological Treatment of Opioid Dependence written by World Health Organization. Department of Mental Health and Substance Abuse and published by World Health Organization. This book was released on 2009 with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt: "These guidelines were produced by the World Health Organization (WHO), Department of Mental Health and Substance Abuse, in collaboration with the United Nations Office on Drugs and Crime (UNODC) a Guidelines Development Group of technical experts, and in consultation with the International Narcotics Control Board (INCB) secretariat and other WHO departments. WHO also wishes to acknowledge the financial contribution of UNODC and the Joint United Nations Programme on HIV/AIDS (UNAIDS) to this project. " - p. iv
Download or read book Drug Policies and Development written by Julia Buxton and published by International Development Poli. This book was released on 2020 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The 12th volume of International Development Policy explores the relationship between international drug policy and development goals, both current and within a historical perspective. Contributions address the drugs and development nexus from a range of critical viewpoints, highlighting gaps and contradictions, as well as exploring strategies and opportunities for enhanced linkages between drug control and development programming. Criminalisation and coercive law enforcement-based responses in international and national level drug control are shown to undermine peace, security and development objectives. Contributors include: Kenza Afsahi, Damon Barrett, David Bewley-Taylor, Daniel Brombacher, Julia Buxton, Mary Chinery-Hesse, John Collins, Joanne Csete, Sarah David, Ann Fordham, Corina Giacomello, Martin Jelsma, Sylvia Kay, Diederik Lohman, David Mansfield, José Ramos-Horta, Tuesday Reitano, Andrew Scheibe, Shaun Shelly, Khalid Tinasti, and Anna Versfeld"--
Download or read book Empire of Pain written by Patrick Radden Keefe and published by Anchor. This book was released on 2021-04-13 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: NEW YORK TIMES BESTSELLER • A NEW YORK TIMES NOTABLE BOOK OF THE YEAR • A grand, devastating portrait of three generations of the Sackler family, famed for their philanthropy, whose fortune was built by Valium and whose reputation was destroyed by OxyContin. From the prize-winning and bestselling author of Say Nothing. "A real-life version of the HBO series Succession with a lethal sting in its tail…a masterful work of narrative reportage.” – Laura Miller, Slate The history of the Sackler dynasty is rife with drama—baroque personal lives; bitter disputes over estates; fistfights in boardrooms; glittering art collections; Machiavellian courtroom maneuvers; and the calculated use of money to burnish reputations and crush the less powerful. The Sackler name has adorned the walls of many storied institutions—Harvard, the Metropolitan Museum of Art, Oxford, the Louvre. They are one of the richest families in the world, but the source of the family fortune was vague—until it emerged that the Sacklers were responsible for making and marketing a blockbuster painkiller that was the catalyst for the opioid crisis. Empire of Pain is the saga of three generations of a single family and the mark they would leave on the world, a tale that moves from the bustling streets of early twentieth-century Brooklyn to the seaside palaces of Greenwich, Connecticut, and Cap d’Antibes to the corridors of power in Washington, D.C. It follows the family’s early success with Valium to the much more potent OxyContin, marketed with a ruthless technique of co-opting doctors, influencing the FDA, downplaying the drug’s addictiveness. Empire of Pain chronicles the multiple investigations of the Sacklers and their company, and the scorched-earth legal tactics that the family has used to evade accountability. A masterpiece of narrative reporting, Empire of Pain is a ferociously compelling portrait of America’s second Gilded Age, a study of impunity among the super-elite and a relentless investigation of the naked greed that built one of the world’s great fortunes.
Download or read book The National Household HIV Prevalence and Risk Survey of South African Children written by Heather Brookes and published by HSRC Press. This book was released on 2004 with total page 62 pages. Available in PDF, EPUB and Kindle. Book excerpt: The National Household HIV Prevalence and Risk Survey of South African Children forms part of the Nelson Mandela/HSRC Study of HIV/AIDS: South African National HIV Prevalence, Behavioural Risks and Mass Media Household Survey 2002. This report provides information on HIV prevalence, orphanhood, risk factors for HIV infection and knowledge of HIV/AIDS among South African children. A total of 3 988 children aged 2 to 18 years participated in the survey. Caregivers of 2 138 children 2 to 11 years of of age answered a questionnaire on the child's behalf. A total of 740 children 12 to 14 years of age directly answered a separate questionnaire. An additional 1 110 children and between 15 and 18 years of age answered a youth questionnaire. Of the 3 988 children, 3 294 (82.6 per cent) provided a saliva specimen for HIV testing. The results show HIV prevalence among children 2 to 18 years of age to be 5.4 per cent. Prevalence was nearly constant across age groups and did not vary significantly. There were insufficient numbers to compare prevalence across race groups. The prevalence was higher than expected. Further studies are necessary to verify this finding.
Download or read book The Mastermind written by Evan Ratliff and published by Random House. This book was released on 2019-01-29 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: The incredible true story of the decade-long quest to bring down Paul Le Roux—the creator of a frighteningly powerful Internet-enabled cartel who merged the ruthlessness of a drug lord with the technological savvy of a Silicon Valley entrepreneur. “A tour de force of shoe-leather reporting—undertaken, amid threats and menacing, at considerable personal risk.”—Los Angeles Times NAMED ONE OF THE BEST BOOKS OF THE YEAR BY The New York Times Book Review • NPR • Evening Standard • Kirkus Reviews It all started as an online prescription drug network, supplying hundreds of millions of dollars’ worth of painkillers to American customers. It would not stop there. Before long, the business had turned into a sprawling multinational conglomerate engaged in almost every conceivable aspect of criminal mayhem. Yachts carrying $100 million in cocaine. Safe houses in Hong Kong filled with gold bars. Shipments of methamphetamine from North Korea. Weapons deals with Iran. Mercenary armies in Somalia. Teams of hit men in the Philippines. Encryption programs so advanced that the government could not break them. The man behind it all, pulling the strings from a laptop in Manila, was Paul Calder Le Roux—a reclusive programmer turned criminal genius who could only exist in the networked world of the twenty-first century, and the kind of self-made crime boss that American law enforcement had never imagined. For half a decade, DEA agents played a global game of cat-and-mouse with Le Roux as he left terror and chaos in his wake. Each time they came close, he would slip away. It would take relentless investigative work, and a shocking betrayal from within his organization, to catch him. And when he was finally caught, the story turned again, as Le Roux struck a deal to bring down his own organization and the people he had once employed. Award-winning investigative journalist Evan Ratliff spent four years piecing together this intricate puzzle, chasing Le Roux’s empire and his shadowy henchmen around the world, conducting hundreds of interviews and uncovering thousands of documents. The result is a riveting, unprecedented account of a crime boss built by and for the digital age. Praise for The Mastermind “The Mastermind is true crime at its most stark and vivid depiction. Evan Ratliff’s work is well done from beginning to end, paralleling his investigative work with the work of the many federal agents developing the case against LeRoux.”—San Francisco Book Review (five stars) “A wholly engrossing story that joins the worlds of El Chapo and Edward Snowden; both disturbing and memorable.”—Kirkus Reviews (starred review)
Download or read book Intoxication written by Ronald K. Siegel and published by Inner Traditions / Bear & Co. This book was released on 2005-03-29 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: Psychopharmacologist Ronald K. Siegel draws on 20 years of groundbreaking research to provide countless examples of the intoxication urge in humans and animals. Presenting his conclusions on the biological and cultural reasons for the pursuit of intoxication, Siegel offers recommendations for curbing the negative effects of drug use in Western culture by designing safe intoxicants.
Download or read book Acute Pain Management written by Pamela E. Macintyre and published by . This book was released on 2010-01-01 with total page 491 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book National Drug Master Plan written by South Africa. Drug Advisory Board and published by . This book was released on 1999 with total page 80 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Substance Use and Abuse in South Africa written by George Ellis and published by Juta and Company (Pty) Ltd. This book was released on 2012-07-04 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: Substance abuse is an enormous social problem in South Africa, as elsewhere. But in South Africa in particular, tik (crystal meth, or methamphetamine) and alcohol are devastating society, aggravating poverty and crime, and contributing to child abuse and gender violence. Substance Use and Abuse in South Africa has arisen out of the thriving Brain-Behaviour Initiative (BBI) at the University of Cape Town, which relates neuroscience and behavioural science to social issues. This ground-breaking book looks at the problem of substance abuse from multiple perspectives and particularly in the light of recent discoveries in brain and behavioural science, but also takes a public health view. Its focus ranges from brain imaging and dopaminergic neurocircuitry to policy and prevention, and is written by local researchers at the cutting edge.
Download or read book World Drug Report 2019 written by United Nations Office on Drugs and Crime and published by . This book was released on 1901 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 2019 World Drug Report will include an updated overview of recent trends on production, trafficking and consumption of key illicit drugs. The Report contains a global overview of the baseline data and estimates on drug demand and supply and provides the reference point for information on the drug situation worldwide.
Download or read book Substance Use and Misuse in sub Saharan Africa written by Magen Mhaka-Mutepfa and published by Springer Nature. This book was released on 2022-01-12 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings together scholars from across the behavioural sciences and public health to examine substance use in Sub-Saharan Africa. Divided into two parts, the first chapters examine aetiology, signs and symptoms, risk factors, impact, and psychosocial challenges relating to use of conventional drugs, among others. The second section focuses on prevention and intervention strategies to curtail substance abuse. The authors provide a research-informed, practical resource on sustainable community health concepts, procedures and practices for addressing substance use for the health and wellbeing of partner communities. The prevention and intervention strategies discussed include a comprehensive consideration of context-specific behavioural, environmental, psychosocial and cultural factors that may affect substance use. The chapters examine various aspects of use including, dependency, intoxication, and withdrawal in tobacco, alcohol, marijuana, and other substances. The book provides a research-informed, practical resource that will appeal to students and scholars of psychology, psychiatry and public health; as well as to policymakers and practitioners in the fields of addiction, development and allied health.
Download or read book The Global Afghan Opium Trade written by and published by UN. This book was released on 2011 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: Opiates originating in Afghanistan threaten the health and well-being of people in many regions of the world. Their illicit trade also adversely impacts governance, security, stability and development in Afghanistan, in its neighbors, in the broader region and beyond. This report, the second such report of the United Nations Office on Drugs and Crime research project on the topic, covers worldwide flows of Afghan opiates, as well as trafficking in precursor chemicals used to turn opium into heroin. By providing a better understanding of the global impact of Afghan opiates, this report can help the international community identify vulnerabilities and possible countermeasures. This report presents data on the distribution of trafficking flows for Afghan opiates and their health impact throughout the world. A worrying development that requires international attention is the increasing use of Africa as a way station for Afghan heroin shipments to Europe, North America and Oceania. This is fuelling heroin consumption in Africa, a region generally ill-equipped to provide treatment to drug users and to fight off the corrupting effects of drug money. Another new trend is the growing use of sea and air transport to move Afghan heroin around the world, as well as to smuggle chemicals used in heroin production into Afghanistan. Traffickers in Afghan heroin have traditionally relied on overland routes, and law enforcement services will need to respond to this new threat. The findings of this report identify areas that need more attention. Strengthening border controls at the most vulnerable points, such as along Afghanistan's border with Pakistan's Baluchistan province, could help stem the largest flows of heroin, opium and precursor chemicals. Increasing the capacity to monitor and search shipping containers in airports, seaports and dry ports at key transit points and in destination countries could improve interdiction rates. Building capacity and fostering intelligence sharing between ports and law enforcement authorities in key countries and regions would help step up interdiction of both opiates and precursor chemicals. Addressing Afghan opium and insecurity will help the entire region, with ripple effects that spread much farther. Enhancing security, the rule of law and rural development are all necessary to achieve sustainable results in reducing poppy cultivation and poverty in Afghanistan. This will benefit the Afghan people, the wider region and the international community as a whole. But addressing the supply side and trafficking is not enough. We need a balanced approach that gives equal weight to counteracting demand for opiates.
Download or read book World Health Organization Guidelines on the Pharmacological Treatment of Persisting Pain in Children with Medical Illnesses written by World Health Organization and published by . This book was released on 2012 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: These guidelines have been developed to support countries to relieve pain in their paediatric populations. These guidelines address persisting pain in children caused by conditions such as cancer, HIV/AIDS, sickle-cell disease, burns, trauma, and phantom limb pain. Recommendations -- developed following a careful and transparent appraisal of available evidence -- are presented for the pharmacological treatment of mild, moderate and severe pain. The guidelines include chapters on the various systems used to classify pain and on the evaluation of pain, which reviews the available tools for routine pain measurement in children. Provision of sustainable pain relief within health care systems is covered in a separate chapter. Since morphine and other opioid analgesics -- required for the relief of moderate-to-severe pain in children -- are listed under the 1961 UN Single Convention on Narcotic Drugs, the new guidelines include an annex explaining the Convention's requirements for the handling and procurement of opioid analgesics for the relief of pain.
Download or read book Opioids written by Silvia L. Cruz and published by Springer Nature. This book was released on 2022-10-03 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: Opioids are responsible for the vast majority of preventable deaths related to drug use, and opioid crisis is a serious international health problem. Opioids are also the mainstay in pain treatment and are invaluable tools in palliative care. The purpose of this book is to present an overview of the complex field of opioid pharmacology through evidence-based chapters in clear language backed up with sound scientific evidence, providing researchers and health professionals with a firm understanding of their effects and mechanisms of action. The authors present an overview of the history of opioids from ancient civilizations to the current opioid crisis, covering state-of-the-art advances on opioid-induced signal transduction, opioids in pain management, and the neuroinflammatory effects of opioids. Also discussed are opioid use disorders and their treatment. The authors also review the growing body of evidence of opioid effects on innate and adaptive immune responses, discussing the molecules involved in the crosstalk between opioids and innate immunity receptors to provide an updated view of those compounds as important regulators of inflammation and host defense against pathogens and damage. The overall purpose is to provide the reader with a deeper knowledge of this field despite the complexities associated with the existence of numerous ligands, receptor subtypes, and complex pharmacological profiles. To this end, the chapter authors are specialists in the field who also have extensive experience in teaching, hoping to lend their expertise in translating complex concepts into comprehensive and clear explanations.
