Download or read book Omics Approaches to Understanding Muscle Biology written by Jatin George Burniston and published by Springer Nature. This book was released on 2019-11-05 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a collection of principles and current practices in omics research, applied to skeletal muscle physiology and disorders. The various sections are categorized according to the level of biological organization, namely, genomics (DNA), transcriptomics (RNA), proteomics (protein), and metabolomics (metabolite). With skeletal muscle as the unifying theme, and featuring contributions from leading experts in this traditional field of research, it highlights the importance of skeletal muscle tissue in human development, health and successful ageing. It also discusses other fascinating topics like developmental biology, muscular dystrophies, exercise, insulin resistance and atrophy due to disuse, ageing or other muscle diseases, conveying the vast opportunities for generating new hypotheses as well as testing existing hypotheses by combining high-throughput techniques with proper experiment designs, bioinformatics and statistical analyses. Presenting the latest research techniques, this book is a valuable resource for the physiology community, particularly researchers and grad students who want to explore the new opportunities for omics technologies in basic physiology research.
Download or read book Methods in Muscle Biology written by Charles Emerson and published by Academic Press. This book was released on 1997 with total page 521 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methods in Muscle Biology is a comprehensive laboratory guide that details the methods used in the study of muscle biology. The techniques included embrace cell, developmental, and molecular biology, as well asphysiology, neurobiology, and medical research.
Download or read book Applied Muscle Biology and Meat Science written by Ph.D., Min Du and published by CRC Press. This book was released on 2009-05-26 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: Knowledge of muscle biology is continuing to expand in the animal and food sciences industry, especially the understanding of the mechanisms that control skeletal muscle development, growth, and their impacts on meat production and quality. Applied Muscle Biology and Meat Science provides agriculturalists with state-of-the-art information and a platform to further explore this specialized topic. It also gives novices a comprehensive knowledge base in applied muscle biology and meat science. Many existing problems in meat science and production are due to a lack of understanding of the underlying biological mechanisms of the livestock. Careful to avoid gory processing details, the text focuses on biological changes and the appropriate manage
Download or read book Systems Biology and Omics Approaches to Understand Complex Diseases Biology written by Amit Kumar Yadav and published by Frontiers Media SA. This book was released on 2022-05-03 with total page 183 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Understanding Skeletal Muscle Adaptation in Health and Chronic Disease written by Peter Kåre Davidsen and published by . This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Exercise Physiology written by Ricardo Ferraz and published by BoD – Books on Demand. This book was released on 2022-11-30 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exercise physiology is one of the most researched sports sciences, with practical implications for health, well-being and sports performance. This book brings together emerging research in this area, presenting the main findings and criticisms, as well as considering the future of exercise physiology.
Download or read book Molecular Exercise Physiology written by Adam P Sharples and published by Routledge. This book was released on 2022-05-11 with total page 549 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fully revised and expanded, the second edition of Molecular Exercise Physiology offers a student-friendly introduction. It introduces a history documenting the emergence of molecular biology techniques to investigate exercise physiology, the methodology used, exercise genetics and epigenetics, and the molecular mechanisms that lead to adaptation after different types of exercise, with explicit links to outcomes in sport performance, nutrition, physical activity and clinical exercise. Structured around key topics in sport and exercise science and featuring contributions from pioneering scientists, such as Nobel Prize winners, this edition includes new chapters based on cutting-edge research in epigenetics and muscle memory, satellite cells, exercise in cancer, at altitude, and in hot and cold climates. Chapters include learning objectives, structured guides to further reading, review questions, overviews of work by key researchers and box discussions from important pioneers in the field, making it a complete resource for any molecular exercise physiology course. The book includes cell and molecular biology laboratory methods for dissertation and research projects in molecular exercise physiology and muscle physiology. This book is essential reading for upper-level undergraduate or postgraduate courses in cellular and molecular exercise physiology and muscle physiology. It is a valuable resource for any student with an advanced interest in exercise physiology in both sport performance and clinical settings.
Download or read book Muscle Biology written by R. G. Cassens (Ed) and published by . This book was released on 1972 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Multi Omics Approaches to Study Signaling Pathways written by Jyoti Sharma and published by Frontiers Media SA. This book was released on 2020-11-18 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Download or read book Chemical and Synthetic Biology Approaches to Understand Cellular Functions Part B written by and published by Academic Press. This book was released on 2019-05-30 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemical and Synthetic Biology Approaches To Understand Cellular Functions - Part B, Volume 622, the latest release in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting chapters that cover the Design of optogenetic proteins, the Application of optogenetic proteins, Antibody aggregation mechanism probed by a fluorescently-labeled antibody with fluorescence correlation spectroscopy, Bimane labeling of B-arrestins to measure their interaction with GPCRs, Reversible biotinylation of proteins for investigating their interaction with partners, Chemical biology approaches to study RNA cytidine acetylation, Salt sensitive intein in robotic production of peptides, and much more. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Methods in Enzymology series - Includes the latest information on methods to measure ubiquitin chain length and linkage and genetic approaches to study the yeast ubiquitin system, amongst other timely topics
Download or read book Integration of Omics Approaches and Systems Biology for Clinical Applications written by Antonia Vlahou and published by John Wiley & Sons. This book was released on 2018-02-21 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduces readers to the state of the art of omics platforms and all aspects of omics approaches for clinical applications This book presents different high throughput omics platforms used to analyze tissue, plasma, and urine. The reader is introduced to state of the art analytical approaches (sample preparation and instrumentation) related to proteomics, peptidomics, transcriptomics, and metabolomics. In addition, the book highlights innovative approaches using bioinformatics, urine miRNAs, and MALDI tissue imaging in the context of clinical applications. Particular emphasis is put on integration of data generated from these different platforms in order to uncover the molecular landscape of diseases. The relevance of each approach to the clinical setting is explained and future applications for patient monitoring or treatment are discussed. Integration of omics Approaches and Systems Biology for Clinical Applications presents an overview of state of the art omics techniques. These methods are employed in order to obtain the comprehensive molecular profile of biological specimens. In addition, computational tools are used for organizing and integrating these multi-source data towards developing molecular models that reflect the pathophysiology of diseases. Investigation of chronic kidney disease (CKD) and bladder cancer are used as test cases. These represent multi-factorial, highly heterogeneous diseases, and are among the most significant health issues in developed countries with a rapidly aging population. The book presents novel insights on CKD and bladder cancer obtained by omics data integration as an example of the application of systems biology in the clinical setting. Describes a range of state of the art omics analytical platforms Covers all aspects of the systems biology approach—from sample preparation to data integration and bioinformatics analysis Contains specific examples of omics methods applied in the investigation of human diseases (Chronic Kidney Disease, Bladder Cancer) Integration of omics Approaches and Systems Biology for Clinical Applications will appeal to a wide spectrum of scientists including biologists, biotechnologists, biochemists, biophysicists, and bioinformaticians working on the different molecular platforms. It is also an excellent text for students interested in these fields.
Download or read book Methods in Muscle Biology written by C. P. Emerson Junior and published by . This book was released on 1997 with total page 493 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book OMICs Technologies written by Noureddine Benkeblia and published by CRC Press. This book was released on 2012-01-24 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the completion of the Human Genome Project, food and nutrition sciences have undergone a fundamental molecular transformation. New discoveries in molecular biology, analytical chemistry, and biochemistry have led to the development of new tools that are likely to revolutionize the study of food. OMICS Technologies: Tools for Food Science explores how these tools reveal the fundamental pathways and biochemical processes that drive food and nutrition sciences. In this volume, an international panel of researchers examines the rise of these new technologies—including metabolomics, metagenomics, nutrigenomics, transcriptomics, and proteomics—and describes how they translate to food science research and productive technologies. The book explains how these methods can be used to assess the quality attributes of foods and food production systems. It explores the principles that regulate food production, analyzes processing and ethical issues, and documents the transformation from industrial to sustained foods production using the OMICS tools. Providing comprehensive information on OMICS and food and nutrition science, this volume is a reliable reference for food scientists, nutritionists, and food product developers looking to implement OMIC technologies in product development. It is also a critical resource for food industry personnel, regulators, and government researchers who need to understand the role of these emerging technologies in advancing food science and nutrition.
Download or read book Systems Biology Approaches to Discerning Striated Muscle Pathologies written by Kavitha Mukund and published by . This book was released on 2016 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: The human muscular system represents nearly 75% of the body mass and encompasses two major muscle forms--striated and smooth. Striated muscle, composed broadly of myofibers, accompanying membrane systems, cytoskeletal networks together with the metabolic and regulatory machinery, have revealed complexities in composition, structure and function. A disruption to any component within this complex system of interactions lead to disorders of the muscle, typically characterized by muscle fiber loss, reduced motor output and in some cases death. Advent of high-throughput technologies coupled with elegant approaches to deciphering data using bioinformatics and systems biology, are providing new venues for detailed exploration of mammalian muscle. This dissertation describes the use of publicly available high-throughput data, in conjunction with co-expression network methodologies developed for a comprehensive, interpretable systems-level perspective on mechanisms underlying associated muscle pathologies. This study begins with the exploration of the temporal transcriptional response of skeletal muscle to Botulinum Neurotoxin-A (Botox®) over a 1-year period, in the framework of muscle physiology. Next, utilizing co-expression network analysis, putative markers associated with recovery of muscle trophicity are identified, furthermore providing an unbiased validation of the response documented earlier. These studies represent the first attempt at categorically assessing the whole-transcriptomic changes associated with BoNT-A treatment in muscle. The latter half of this research focuses on discerning patho-mechanisms of human diseases affecting muscle. Particularly, co-expression network statistics are leveraged to identify dysregulated pathways and biomarkers of disease progression, underlying duchenne muscular dystrophy. Next, a quantitative framework integrating transcriptional, protein interaction, and drug-target data is developed to extract functional similarities and mechanisms amongst 20 diseases affecting the muscle. Lastly, an approach to differential co-expression analysis using signed and weighted co-expression networks is described. This approach is subsequently utilized to assess and identify differential mechanisms underlying ischemic and idiopathic dilated cardiomyopathy. The analysis and results from the aforementioned studies have enabled a deeper understanding of the complex interactions underlying muscle pathologies; providing opportunities for drug development and personalized medicine.
Download or read book Issues in Life Sciences Muscle Membrane and General Microbiology 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 1409 pages. Available in PDF, EPUB and Kindle. Book excerpt: Issues in Life Sciences: Muscle, Membrane, and General Microbiology: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Life Sciences—Muscle, Membrane, and General Microbiology. The editors have built Issues in Life Sciences: Muscle, Membrane, and General Microbiology: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Life Sciences—Muscle, Membrane, and General Microbiology in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Life Sciences: Muscle, Membrane, and General Microbiology: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Download or read book Systems Biology Approaches Prevention Diagnosis and Understanding Mechanisms of Complex Diseases written by Sanket Joshi and published by Springer Nature. This book was released on with total page 587 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Recent Advances in OMICs Technologies and Application for Ensuring Meat Quality Safety and Authenticity written by Mohammed Gagaoua and published by Mdpi AG. This book was released on 2023-01-09 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Consumers and stakeholders are increasingly demanding that the meat industry guarantees high-quality meat products with stable and acceptable sensory and safety properties. To do this, it is necessary to understand the mechanisms that underlie the conversion of muscle into meat, as well as the impact of pre- and post-harvest procedures on the final quality and safety of meat products. Over the last two decades, sophisticated OMICs technologies-genomics, transcriptomics, proteomics, peptidomics, metabolomics and lipidomics, also known as foodomics-have been powerful approaches that extended the scope of traditional methods and have established impressive possibilities of addressing meat quality issues. Foodomics were further used to elucidate the biological basis/mechanisms of phenotypic variation in the technological and sensory quality traits of meat from different species. Overall, these techniques aimed to comprehensively study the dynamic link(s) between the genome and the quality traits of the meat that we eat compared to traditional methods, hence improving both the accuracy and sensitivity thanks to the large quantities of data that can be generated. This Special Issue focused on the cutting-edge research applications of OMICs tools to characterize or manage the quality of muscle foods. The research papers applied transcriptomics, targeted and untargeted proteomics, metabolomics, and genomics, among others, to evaluate meat quality, determine the molecular profiles of meat and meat products, discover and/or evaluate biomarkers of meat quality traits, and to characterize the safety, adulteration, and authenticity of meat and meat products.
