Download or read book OECD Guidelines for the Testing of Chemicals Section 2 Test No 230 21 day Fish Assay A Short Term Screening for Oestrogenic and Androgenic Activity and Aromatase Inhibition written by OECD and published by OECD Publishing. This book was released on 2009-09-08 with total page 38 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline describes an in vivo screening assay for certain endocrine active substances where sexually mature male and spawning female fish are held together and exposed to a chemical during a limited part of their life-cycle (21 days ...
Download or read book OECD Guidelines for the Testing of Chemicals Section 2 Test No 234 Fish Sexual Development Test written by OECD and published by OECD Publishing. This book was released on 2011-07-28 with total page 44 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline describes an assay that assesses early life-stage effects and potential adverse consequences of putative endocrine disrupting chemicals (e.g. oestrogens, androgens and steroidogenesis inhibitors) on fish sexual development. In ...
Download or read book OECD Guidelines for the Testing of Chemicals Section 2 Test No 229 Fish Short Term Reproduction Assay written by OECD and published by OECD Publishing. This book was released on 2012-10-02 with total page 40 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline describes an in vivo screening assay for fish reproduction where sexually mature male and spawning female fish are held together and exposed to a chemical during a limited part of their life-cycle (21 days). The short term ...
Download or read book OECD Guidelines for the Testing of Chemicals OECD Series on Testing and Assessment Detailed Review Paper on Fish Screening Assays for the Detection of Endocrine Active Substances written by OECD and published by OECD Publishing. This book was released on 2004-11-01 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Detailed Review Paper (DRP) is intended to provide the current state-of-the-knowledge in the area of fish screening assays for chemicals active at the endocrine level on the reproductive system of test animals.
Download or read book Test No 229 Fish Short Term Reproduction Assay written by OECD and published by OECD Publishing. This book was released on 2009-09-08 with total page 40 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline describes an in vivo screening assay for fish reproduction where sexually mature male and spawning female fish are held together and exposed to a chemical during a limited part of their life-cycle (21 days). The short term ...
Download or read book OECD Guidelines for the Testing of Chemicals Section 2 Test No 251 Rapid Androgen Disruption Activity Reporter RADAR assay written by OECD and published by OECD Publishing. This book was released on 2022-06-30 with total page 44 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Rapid Androgen Disruption Activity Reporter (RADAR) Test Guideline describes an aquatic assay that utilizes transgenic Oryzias latipes (O. latipes, Japanese medaka) eleutheroembryos at day post hatch zero, in a multi-well format to detect chemicals active on the androgen axis.
Download or read book OECD Guidelines for the Testing of Chemicals Section 2 Test No 210 Fish Early life Stage Toxicity Test written by OECD and published by OECD Publishing. This book was released on 2013-07-26 with total page 24 pages. Available in PDF, EPUB and Kindle. Book excerpt: The test method described in this Test Guideline, is intended to define the lethal and sub-lethal effects of chemicals on the early life stages of the species tested. The early-life stages of fish are exposed to five concentrations of the test ...
Download or read book OECD Guidelines for the Testing of Chemicals Section 2 Test No 240 Medaka Extended One Generation Reproduction Test MEOGRT written by OECD and published by OECD Publishing. This book was released on 2023-07-04 with total page 53 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline describes the Medaka Extended One Generation Test (MEOGRT), which exposes fish over multiple generations to give data relevant to ecological hazard and risk assessment of chemicals, including suspected endocrine disrupting chemicals (EDCs). Exposure in the MEOGRT starts with ...
Download or read book OECD Guidelines for the Testing of Chemicals OECD Series on Testing and Assessment Detailed Review Paper on Fish Screening Assays for the Detection of Endocrine Active Substances written by OECD and published by OECD Publishing. This book was released on 2004-11-01 with total page 171 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Detailed Review Paper (DRP) is intended to provide the current state-of-the-knowledge in the area of fish screening assays for chemicals active at the endocrine level on the reproductive system of test animals.
Download or read book OECD Guidelines for the Testing of Chemicals Section 2 Test No 250 EASZY assay Detection of Endocrine Active Substances acting through estrogen receptors using transgenic tg cyp19a1b GFP Zebrafish embrYos written by OECD and published by OECD Publishing. This book was released on 2021-06-17 with total page 45 pages. Available in PDF, EPUB and Kindle. Book excerpt: The EASZY assay is a mechanism-based in vivo screening assay designed to detect endocrine active chemicals acting as agonist through estrogen receptors (ERs), by inducing the expression of the green fluorescent protein (GFP) driven by the cyp19a1b promoter. The EASZY assay allows for the detection of estrogenic activity of chemicals on transgenic tg(cyp19a1b:GFP) Zebrafish embryos exposed for 96 hours during the embryonic stages of development.
Download or read book OECD Guidelines for the Testing of Chemicals Section 4 Test No 441 Hershberger Bioassay in Rats A Short term Screening Assay for Anti Androgenic Properties written by OECD and published by OECD Publishing. This book was released on 2009-09-08 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Hershberger Bioassay is an in vivo short–term screening test. It evaluates the ability of a chemical to elicit biological activities consistent with androgen agonists, antagonists or 5 á-reductase inhibitors. The current bioassay is based on the ...
Download or read book OECD Guidelines for the Testing of Chemicals OECD Series on Testing and Assessment Detailed Review Paper Appraisal of Test Methods for Sex Hormone Disrupting Chemicals written by OECD and published by OECD Publishing. This book was released on 2002-05-10 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: This documents servies as the basis for the first step in the consideration and development of OECD Test Guidelines for the testing of chemicals for endocrine-disrupting effects.
Download or read book OECD Guidelines for the Testing of Chemicals Section 2 Effects on Biotic Systems Test No 215 Fish Juvenile Growth Test written by OECD and published by OECD Publishing. This book was released on 2000-01-21 with total page 17 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline is designed to assess the effects of prolonged exposure to chemicals on the growth of juvenile fish. Juvenile fish in exponential growth phase are placed, after being weighed, in test chambers and are normally exposed to five ...
Download or read book Medaka written by Kenji Murata and published by John Wiley & Sons. This book was released on 2019-09-10 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explains the advantages of using medaka in experimental designs, to facilitate research, and to stimulate progress by adopting medaka as a model animal The second volume of Medaka: Biology, Management, and Experimental Protocols, together with the first volume, helps to familiarize scientists with the advantages of using medaka in experimental designs, to facilitate research using medaka, and to stimulate progress by adopting medaka as a model animal. The second edition expands on the first by providing additional information and current protocols that have been recently developed, or modified, to successfully raise medaka fish under stable culture conditions in the laboratory. This volume explores new technologies developed after 2009, using the fish as a molecular tool in the fields of life science, evolution, ecology, and toxicology. The authors—noted experts in the field—provide the latest information that spans the varied research disciplines and addresses the value to science of medaka's adoption as a model animal. This important book: Explores the advantages of using medaka in experimental designs, to facilitate research Details the most recent protocols to successfully raise medaka fish under stable conditions in the laboratory Explores the most recent developments in the field Provides step-by step specifics for each protocol, allowing researchers to adapt them for use in their own work Written for students and researchers in fish biology and aquaculture, Medaka: Biology, Management, and Experimental Protocols, Volume 2 introduces the cutting edge research in basic and applied biology using medaka as a model animal as well as descriptions of experimental methods and protocols.
Download or read book A Systems Biology Approach to Advancing Adverse Outcome Pathways for Risk Assessment written by Natàlia Garcia-Reyero and published by Springer. This book was released on 2018-02-24 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: Social pressure to minimize the use of animal testing, the ever-increasing concern on animal welfare, and the need for more human-relevant and more predictive toxicity tests are some of the drivers for new approaches to chemical screening. This book focuses on The Adverse Outcome Pathway, an analytical construct that describes a sequential chain of causally linked events at different levels of biological organization that lead to an adverse health or ecotoxicological effect. While past efforts have focused on toxicological pathway-based vision for human and ecological health assessment relying on in vitro systems and predictive models, The Adverse Outcome Pathway framework provides a simplified and structured way to organize toxicological information. Within the book, a systems biology approach supplies the tools to infer, link, and quantify the molecular initiating events and the key events and key event relationships leading to adverse outcomes. The advancement of these tools is crucial for the successful implementation of AOPs for regulatory purposes.
Download or read book OECD Series on Testing and Assessment Guidance Document on Aquatic Toxicity Testing of Difficult Substances and Mixtures written by OECD and published by OECD Publishing. This book was released on 2019-05-16 with total page 81 pages. Available in PDF, EPUB and Kindle. Book excerpt: This document provides the second edition of Guidance Document 23 on Aqueous-Phase Aquatic Toxicity Testing of Difficult Test Chemicals.
Download or read book An Introduction to Interdisciplinary Toxicology written by Carey N. Pope and published by Academic Press. This book was released on 2020-02-18 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt: An Introduction to Interdisciplinary Toxicology: From Molecules to Man integrates the various aspects of toxicology, from “simple molecular systems, to complex human communities, with expertise from a spectrum of interacting disciplines. Chapters are written by specialists within a given subject, such as a chemical engineer, nutritional scientist, or a microbiologist, so subjects are clearly explained and discussed within the toxicology context. Many chapters are comparative across species so that students in ecotoxicology learn mammalian toxicology and vice versa. Specific citations, further reading, study questions, and other learning features are also included. The book allows students to concurrently learn concepts in both biomedical and environmental toxicology fields, thus better equipping them for the many career opportunities toxicology provides. This book will also be useful to those wishing to reference how disciplines interact within the broad field of toxicology. Covers major topics and newer areas in toxicology, including nanotoxicology, Tox21, epigenetic toxicology, and organ-specific toxicity Includes a variety of perspectives to give a complete understanding of toxicology Written by specialists within each subject area, e.g., a chemical engineer, to ensure concepts are clearly explained
