Download or read book Ocular neurodegenerative diseases Novel mechanisms diagnosis and therapeutic strategies written by Dan Wen and published by Frontiers Media SA. This book was released on 2023-11-06 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Neurodegenerative Diseases written by Shamim I. Ahmad and published by Springer Science & Business Media. This book was released on 2012-03-12 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: The editor of this volume, having research interests in the field of ROS production and the damage to cellular systems, has identified a number of enzymes showing ·OH scavenging activities details of which are anticipated to be published in the near future as confirmatory experiments are awaited. It is hoped that the information presented in this book on NDs will stimulate both expert and novice researchers in the field with excellent overviews of the current status of research and pointers to future research goals. Clinicians, nurses as well as families and caregivers should also benefit from the material presented in handling and treating their specialised cases. Also the insights gained should be valuable for further understanding of the diseases at molecular levels and should lead to development of new biomarkers, novel diagnostic tools and more effective therapeutic drugs to treat the clinical problems raised by these devastating diseases.

Download or read book Novel Diagnostic and Therapeutic Strategies for Retinal Diseases written by Shaochong Zhang and published by Frontiers Media SA. This book was released on 2022-10-25 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Etiology of Parkinson s Disease written by Jonas H. Ellenberg and published by CRC Press. This book was released on 1995-03-01 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive reference provides a detailed overview of current concepts regarding the cause of Parkinson's disease-emphasizing the issues involved in the design, implementation, and analysis of epidemiological studies of parkinsonism.

Download or read book Brain vs Retina Differences and Commonalities The Role of Oxidative Stress in Neurodegenerative Diseases written by Jose Hurst and published by Frontiers Media SA. This book was released on 2023-06-15 with total page 109 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oxidative stress, free radicals, antioxidants - when it comes to our health, this topic is taking up more and more attention. But what is oxidative stress, how does it arise and what effects does it have on the most sensitive area of our body: the neuronal tissue or the retina. Many neurological diseases affecting the brain or the retina are associated with elevated levels of reactive oxygen species (ROS). High levels of ROS can cause damage to proteins, nucleic acids, lipids, membranes, and organelles such as mitochondria, and can be caused not only by external stimuli but also by aging. Most theories on the aging scenario assume that cumulative oxidative stress leads to mitochondrial changes, mitochondrial dysfunction, and oxidative damage. Therefore, it is not surprising that excess ROS is among others associated with the development of a variety of age-related neuronal diseases, including Alzheimer's and Parkinson's disease, as well as retinal diseases diabetic retinopathy, glaucoma, and age-related macular (AMD) degeneration. The aim of this Research Topic is to answer open questions, to combine already gained knowledge, to close the gaps between ophthalmology and neurology when it comes to oxidative stress in order to understand the underlying pathways and derive innovative therapies. It searches for the updates and new findings in both fields that answer the central question: are the same cell types affected by oxidative stress in the same way in the brain and retina? Experimental studies or patient studies that provide new insights are welcome, as well as studies that investigate antioxidant therapies.

Download or read book Seeing Beyond the Eye The Brain Connection written by Christine Nguyen and published by Frontiers Media SA. This book was released on 2021-09-02 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Webvision written by Helga Kolb and published by . This book was released on 2007 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Ocular Motor and Vestibular Function in Neurometabolic Neurogenetic and Neurodegenerative Disorders written by Aasef G. Shaikh and published by Frontiers Media SA. This book was released on 2018-08-29 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: Eye movements provide rich source of information about brain functioning for neurologists and neuroscientists. They provide diagnostic clues, define, and localize motor and cognitive disorders. Objective eye movement assessments associated with clinical observation and genetic testing in neurodegenerative, neurometabolic, and neurogenetic diseases provide insight into their pathophysiology and disease mechanism. Finally the eye movements may be used for testing and following the response to therapies. The concrete value of studying eye movement stems from a number of advantages compared to the study of movements of axial or limb muscles. The eye movements are accessible to clinical inspection, they can be measured precisely, their interpretation is clear and therefore ocular motility examination has high localization value. There are several standardized tasks to study of each subclass of eye movements that are recognized for motor or cognitive behavior. Indeed the studies of eye movement had allowed test of motor and cognitive functions of the brain in a vast range of neurological disease. Both cortical and subcortical dysfunctions may be detected with the analysis of subclasses of eye movements and interpreted in association with other clinical, laboratory and neuroimaging features. The goal of this topic-focused volume of Frontiers in Neurology is to gather seminal studies, from well-known scientists and laboratories from across the world, delineating the features of eye movements and vestibular system in neurogenetic, neurometabolic, and neurodegenerative disorders. Such collection of articles, to our knowledge, is unique and never done in the past. The topics and the compilation will be of interest to broad groups of neuroscientists and neurologists for the reasons as follows: 1) Neurodegenerative diseases represent a large portion of neurological diseases encountered in neurological clinical practice. Eye movement changes may occur early in their course and may be specific, thus orienting the diagnosis. 2) Neurometabolic and neurogenetic conditions, although rare, show specific and characteristic eye movements that represent the hallmark of the disease. Such disorders often represent a pathologic model that helps to understand the normal functioning of specific brain regions and networks.

Download or read book Frontiers in Clinical Drug Research Alzheimer Disorders written by Atta-ur-Rahman and published by Bentham Science Publishers. This book was released on 2017-07-31 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt: Frontiers in Clinical Drug Research - Alzheimer Disorders is a book series concerned with Alzheimer's disease (AD) that causes dementia, or loss of brain function. The disease affects the parts of the brain that deal with memory, thought, and language. Chapters in each volume focus on (Alzheimer Disorders) drug research with special emphasis on clinical trials, research on drugs in advanced stages of development and cure for Alzheimer’s disease and related disorders. Frontiers in Clinical Drug Research - Alzheimer Disorders will be of particular interest to readers interested in drug therapy of this specific neurodegenerative condition and related brain disorders as the series provides relevant reviews written by experts in field of Alzheimer’s disease research.

Download or read book Primary Glial and Immune Cell Pathology in Neurodegenerative Diseases written by Andras Lakatos and published by Frontiers Media SA. This book was released on 2021-12-21 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Ocular Pathology written by Myron Yanoff and published by Elsevier Health Sciences. This book was released on 2018-12-05 with total page 899 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bridge the gap between ophthalmology and pathology with the 8th Edition of this comprehensive, easy-to-understand reference from Drs. Myron Yanoff and Joseph W. Sassani. Designed to keep you up to date with every aspect of the field, from current imaging techniques to genetics and molecular biology to clinical pearls, Ocular Pathology provides the concise yet complete information you need for board exams and clinical practice. Includes new coverage of genetics and molecular biology, complications in diabetes mellitus, and the role of new drugs and other treatments for macular degeneration. Covers the latest imaging techniques, including optical coherence tomography (OCT), anterior segment OCT (AS-OCT) and OCT-angiography. Contains new images throughout that provide updated correlations between pathological and clinical aspects of each disorder. Clinicopathological correlations are presented with side-by-side image comparisons to make clinical pearl boxes even more useful. Features more than 1,900 illustrations from the collections of internationally renowned leaders in ocular pathology. Presents information in a quick-reference outline format – ideal for today’s busy physician.

Download or read book Retinal Degeneration and Therapy Approaches written by Nicolás Cuenca and published by Frontiers Media SA. This book was released on 2022-04-18 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Drug Delivery Devices and Therapeutic Systems written by Eric Chappel and published by Academic Press. This book was released on 2020-11-07 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Delivery Devices and Therapeutic Systems examines the current technology and innovations moving drug delivery systems (DDS) forward. The book provides an overview on the therapeutic use of drug delivery devices, including design, applications, and a description of the design of each device. While other books focus on the therapy, the primary emphasis in this book is on current technologies for DDS applications, including microfluidics, nanotechnology, biodegradable hydrogel and microneedles, with a special emphasis on wearable DDS. As part of the Developments in Biomedical Engineering and Bioelectronics series, this book is written by experts in the field and informed with information directly from manufacturers. Pharmaceutical scientists, medical researchers, biomedical engineers and clinical professionals will find this an essential reference. Provides essential information on the most recent drug delivery systems available Explains current technology and its applications to drug delivery Contains contributions from biomedical engineers, pharmaceutical scientists and manufacturers

Download or read book Pediatric Neuro Ophthalmology written by Michael C. Brodsky and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 692 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pediatric Neuroophthalmology details the diagnostic criteria, current concepts of pathogenesis, neuroradiological correlates, and clinical management of a large group of neuroophthalmic disorders that present in childhood. Surprisingly distinct from neuroophthalmic disorders afflicting adults, this set of diseases falls between the cracks of most ophthalmology training, and thus, warrants a practical, clinical guide for the practitioner in ophthalmology - the neuroophthalmologist, pediatric ophthalmologist, general ophthalmologist - as well as neurologists and for residents. The authors, leading pediatric ophthalmologists, have taken this difficult subject matter and developed an accessible, user-friendly manual with a detailed approach to the recognition, differential diagnosis, and management of pediatric neuroophthalmologic disorders.

Download or read book Leucine Rich Repeat Kinase 2 LRRK2 written by Hardy J. Rideout and published by Springer. This book was released on 2017-03-28 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first book to assemble the leading researchers in the field of LRRK2 biology and neurology and provide a snapshot of the current state of knowledge, encompassing all major aspects of its function and dysfunction. The contributors are experts in cell biology and physiology, neurobiology, and medicinal chemistry, bringing a multidisciplinary perspective on the gene and its role in disease. The book covers the identification of LRRK2 as a major contributor to the pathogenesis of Parkinson's Disease. It also discusses the current state of the field after a decade of research, putative normal physiological roles of LRRK2, and the various pathways that have been identified in the search for the mechanism(s) of its induction of neurodegeneration.

Download or read book Optical Coherence Tomography Angiography of the Eye written by David Huang and published by Kugler Publications. This book was released on 2024-01-08 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt: Optical coherence tomography angiography (OCTA) has undergone tremendous growth since its first commercial introduction in 2014. Because it provides injection-free, capillary-resolution, 3-dimensional angiography of the retina and choroid, OCTA is likely to overtake fluorescein as the most important angiographic imaging technique in the eye. Nearly all manufacturers of ophthalmic OCT now offer OCTA products. A PubMed search now yields over 5700 articles on OCTA and related terms. Clinical investigators have already found a use for OCTA in almost every category of retinal and optic nerve diseases. This book is meant to bring together all this information so clinicians can have one authoritative text to turn to as we begin to use this new imaging modality that was never taught when we were in formal training. Table of contents Introduction Dedication About the Editors Contributors 1. Optical coherence tomography systems for angiography 2. Optical coherence tomographic angiography algorithms 3. Vascular anatomy of the normal retina and choroid 4. OCTA of the normal anterior eye circulations 5. Artifacts 6. Quantification 7. Artificial intelligence in optical coherence tomographic angiography 8. Terminology: a new standard 9. AngioVue SSADA OCTA on the Optovue SOLIX Spectral-Domain OCT 10. Optical microangiography with AngioPlex® and PLEX® Elite systems 11. Optical coherence tomography angiography imaging on the Topcon Triton and Maestro2 systems 12. NIDEK Mirante OCT angiography 13. OCTA on the Heidelberg spectralis spectral-domain OCT 14. OCTA on the Optopol REVO NX spectral-domain OCT 15. OCTA on the Canon OCT-HS100 and Xephilio OCT-A1 Spectral-Domain OCT 16. Exudative neovascular age-related macular degeneration—Type 1, 2 and 3 neovascularization 17. Retinal angiomatous proliferation—type 3 choroidal neovascularization 18. Short- and long-term follow-up of macular neovascularization response to antiangiogenic treatment 19. Nonexudative neovascular age-related macular degeneration 20. Non-neovascular age-related macular degeneration 21. Polypoidal choroidal vasculopathy 22. Macular telangiectasia 23. Central serous chorioretinopathy 25. Nonproliferative diabetic retinopathy 26. Subclinical neovascular diabetic retinopathy 27. Proliferative diabetic retinopathy 28. Retinal venous occlusion 29. Retinal arterial occlusion 30. Plexus-specific occlusions in retinal vascular diseases 31. Paracentral acute middle maculopathy 32. Inherited retinal degenerations 33. Pathologic myopia 34. Multimodal imaging and the role of optical coherence tomography angiography in retinal vasculitis 35. White spot syndromes 36. Choroidal tumors 37. Radiation retinopathy 38. Open-angle glaucoma 39. Primary angle-closure glaucoma 40. Optic neuritis and multiple sclerosis 41. Alzheimer’s disease 42. Corneal neovascularization 43. Ocular surface and iris tumors

Download or read book Translational Advances in Alzheimer s Parkinson s and other Dementia Molecular Mechanisms Biomarkers Diagnosis and Therapies Volume II written by Jiehui Jiang and published by Frontiers Media SA. This book was released on 2022-11-15 with total page 713 pages. Available in PDF, EPUB and Kindle. Book excerpt: