Download or read book Novel Optical Resolution Technologies written by Kenichi Sakai and published by Springer Science & Business Media. This book was released on 2007-02-15 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: After theend ofthe 20th century, the science ofcrystallizationreached a truly exciting stage where new opportunities emerged in both theory and expe- ment. Variousphysical methodsare capableofresolvingthesurface as wellas theinsidestructureofcrystalsattheatomiclevelwhilenewhigh-performance computingresourcesaffordthecapabilityofmodelingthecomplexlarge-scale alignmentsnecessarytosimulatecrystallizationinrealsystems.Asaresult,the science of crystallization has shifted gradually fromstatic to dynamic science and considerable progress now underlies the complex but beautiful cryst- lization process. I believe that if a de'nitive history of 21st century science is ever written,one of the highlightswill be the science ofcrystallization. This science has the following characteristics: in'nite advances in soph- tication, unlimited opportunities not only for intellectual excitement but also forindustrialmerit,strongcollaborationwithbiologyandmaterialscience,as wellaswithallareasofchemistry.Thevastpotentialofcrystallizationasan- portant'eld ofscience isfar beyondthesimple technologyofpharmaceutical industries during the 20th century. Optical resolution was one small area of chemistry in the last century. This was more a technology than a science, largely because trial and error was the only method to obtain good results. However, the situation is now changing. Therearesomanyappealing,hidden'ndingsintheprocessofcrystallization. Historically, crystallization began in an old laboratory in academia and then gradually shifted to industry. Now,it is making itscomeback in academia due toseveralnewresearchbranchestryingtodiscoverwhatisgoingonduringthe crystallizationprocess.Ibelieve this'eld ofscience isnowgrowingasa result of the wonderfulcoupling between industry and academia. I read a prepublication draft of Novel Optical Resolution Technologies,and foundthateachoneofthesegeneralcharacteristicsofsciencehadarealityand sharpness that I had not expected. While it was a sheer delight to revisit each of these triumphs guided by the wise insights and analyses found throughout the book. There is a good balance between the underlying historical material and the design and execution aspects of each topic.
Download or read book Laboratory Unit Operations and Experimental Methods in Chemical Engineering written by Omar M. Basha and published by BoD – Books on Demand. This book was released on 2018-10-10 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers a wide variety of topics related to the application of experimental methods, in addition to the pedagogy of chemical engineering laboratory unit operations. The purpose of this book is to create a platform for the exchange of different experimental techniques, approaches and lessons, in addition to new ideas and strategies in teaching laboratory unit operations to undergraduate chemical engineering students. It is recommended for instructors and students of chemical engineering and natural sciences who are interested in reading about different experimental setups and techniques, covering a wide range of scales, which can be widely applied to many areas of chemical engineering interest.
Download or read book Frontiers Of Organofluorine Chemistry written by Iwao Ojima and published by World Scientific. This book was released on 2019-12-24 with total page 842 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the new frontiers of organofluorine chemistry in synthetic, organometallic, bioorganic, medicinal, agricultural, and materials chemistry as well as chemical physics and their applications to biomedical and material sciences. The extraordinary potential of fluorine-containing molecules in biology, pharmaceuticals, agrochemical, materials and their wide range of applications has been recognized by researchers who are not in the traditional fluorine chemistry field, and thus the new wave of organofluorine chemistry is rapidly expanding its frontiers.Featuring major leading researchers from all over the world and their cutting-edge research projects, this title reviews the recent advances and envision the new exciting developments in the future. Frontiers of Organofluorine Chemistry is an excellent reference book for professional researchers, and graduate students, in both industry and academia to get inspirations and new ideas for their projects.
Download or read book Chirality at the Nanoscale written by David B. Amabilino and published by John Wiley & Sons. This book was released on 2009-02-11 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: The only standard reference in this exciting new field combines the physical, chemical and material science perspectives in a synergic way. This monograph traces the development of the preparative methods employed to create nanostructures, in addition to the experimental techniques used to characterize them, as well as some of the surprising physical effects. The chapters cover every category of material, from organic to coordination compounds, metals and composites, in zero, one, two and three dimensions. The book also reviews structural, chemical, optical, and other physical properties, finishing with a look at the future for chiral nanosystems.
Download or read book Creative Chemical Sensor Systems written by Thomas Schrader and published by Springer. This book was released on 2007-05-09 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: With contributions by numerous experts
Download or read book Computational Optical Phase Imaging written by Cheng Liu and published by Springer Nature. This book was released on 2022-04-11 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, computational optical phase imaging techniques are presented along with Matlab codes that allow the reader to run their own simulations and gain a thorough understanding of the current state-of-the-art. The book focuses on modern applications of computational optical phase imaging in engineering measurements and biomedical imaging. Additionally, it discusses the future of computational optical phase imaging, especially in terms of system miniaturization and deep learning-based phase retrieval.
Download or read book Comprehensive Organic Chemistry Experiments for the Laboratory Classroom written by Carlos A M Afonso and published by Royal Society of Chemistry. This book was released on 2020-08-28 with total page 976 pages. Available in PDF, EPUB and Kindle. Book excerpt: This expansive and practical textbook contains organic chemistry experiments for teaching in the laboratory at the undergraduate level covering a range of functional group transformations and key organic reactions.The editorial team have collected contributions from around the world and standardized them for publication. Each experiment will explore a modern chemistry scenario, such as: sustainable chemistry; application in the pharmaceutical industry; catalysis and material sciences, to name a few. All the experiments will be complemented with a set of questions to challenge the students and a section for the instructors, concerning the results obtained and advice on getting the best outcome from the experiment. A section covering practical aspects with tips and advice for the instructors, together with the results obtained in the laboratory by students, has been compiled for each experiment. Targeted at professors and lecturers in chemistry, this useful text will provide up to date experiments putting the science into context for the students.
Download or read book Advances in Organic Crystal Chemistry written by Rui Tamura and published by Springer. This book was released on 2015-08-06 with total page 699 pages. Available in PDF, EPUB and Kindle. Book excerpt: For the last decade, the topics of organic crystal chemistry have become diversified, and each topic has been substantially advanced in concert with the rapid development of various analytical and measurement techniques for solid-state organic materials. The aim of this book is to systematically summarize and record the recent notable advances in various topics of organic crystal chemistry involving liquid crystals and organic–inorganic hybrid materials that have been achieved mainly in the last 5 years or so. The authors are invited members of the Division of Organic Crystals, The Chemical Society of Japan (CSJ), and prominent invited experts from abroad. This edited volume is planned to be published periodically, at least every 5 years, with contributions by prominent authors in Japan and from abroad.
Download or read book Polymorphism in the Pharmaceutical Industry written by Rolf Hilfiker and published by John Wiley & Sons. This book was released on 2019-04-29 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Polymorphism in the Pharmaceutical Industry - Solid Form and Drug Development" highlights the relevance of polymorphism in modern pharmaceutical chemistry, with a focus on quality by design (QbD) concepts. It covers all important issues by way of case studies, ranging from properties and crystallization, via thermodynamics, analytics and theoretical modelling right up to patent issues. As such, the book underscores the importance of solid-state chemistry within chemical and pharmaceutical development. It emphasizes why solid-state issues are important, the approaches needed to avoid problems and the opportunities offered by solid-state properties. The authors include true polymorphs as well as solvates and hydrates, while providing information on physicochemical properties, crystallization thermodynamics, quantum-mechanical modelling, and up-scaling. Important analytical tools to characterize solid-state forms and to quantify mixtures are summarized, and case studies on solid-state development processes in industry are also provided. Written by acknowledged experts in the field, this is a high-quality reference for researchers, project managers and quality assurance managers in pharmaceutical, agrochemical and fine chemical companies as well as for academics and newcomers to organic solid-state chemistry.
Download or read book Recrystallization written by Krzysztof Sztwiertnia and published by BoD – Books on Demand. This book was released on 2012-03-07 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recrystallization shows selected results obtained during the last few years by scientists who work on recrystallization-related issues. These scientists offer their knowledge from the perspective of a range of scientific disciplines, such as geology and metallurgy. The authors emphasize that the progress in this particular field of science is possible today thanks to the coordinated action of many research groups that work in materials science, chemistry, physics, geology, and other sciences. Thus, it is possible to perform a comprehensive analysis of the scientific problem. The analysis starts from the selection of appropriate techniques and methods of characterization. It is then combined with the development of new tools in diagnostics, and it ends with modeling of phenomena.
Download or read book Pharmaceutical Salts and Co crystals written by Johan Wouters and published by Royal Society of Chemistry. This book was released on 2011 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the hot topic of pharmaceutical salts and co-crystals focusing on the following essential aspects: an overview of fundamental aspects on salts and co-crystals, racemic resolution via diastereomer separation, optimization of relevant physico-chemical parameters, and strengthening of intellectual property.
Download or read book Chirality in Supramolecular Assemblies written by F. Richard Keene and published by John Wiley & Sons. This book was released on 2017-01-03 with total page 722 pages. Available in PDF, EPUB and Kindle. Book excerpt: Supramolecular chemistry deals with the organisation of molecules into defined assemblies using non-covalent interactions, including weaker and reversible interactions such as hydrogen bonds, and metal-ligand interactions. The aspect of stereochemistry within such chemical architectures, and in particular chirality, is of special interest as it impacts on considerations of molecular recognition, the development of functional materials, the vexed question of homochirality, nanoscale effects of interactions at interfaces, biocatalysis and enzymatic catalysis, and applications in organic synthesis. Chirality in Supramolecular Assemblies addresses many of these aspects, presenting a broad overview of this important and rapidly developing interdisciplinary field. Topics covered include: Origins of molecular and topological chirality Homochirogenesis Chirality in crystallinity Host-guest behavior Chiral influences in functional materials Chirality in network solids and coordination solids Aspects of chirality at interfaces Chirality in organic assemblies Chirality related to biocatalysis and enzymes in organic synthesis. This book is a valuable reference for researchers in the molecular sciences, materials science and biological science working with chiral supramolecular systems. It provides summaries and special insights by acknowledged international experts in the various fields.
Download or read book Disordered Pharmaceutical Materials written by Marc Descamps and published by John Wiley & Sons. This book was released on 2016-03-28 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: A one-stop resource for researchers, developers, and post graduate students in pharmaceutical science. This handbook and ready reference provides detailed, but not overloaded information -- presenting the topic without unnecessarily complex formalism. As such, it gives a systematic and coherent overview of disordered materials for pharmaceutical applications, covering fundamental aspects, as well as preparation and characterization techniques for the target-oriented development of drug delivery systems based on disordered crystals and amorphous solids. Special attention is paid to examine the different facets and levels of disorder in their structural and dynamic aspects as well as the effect of disorder on dissolution and stability. Chapters on processing induced disorder and on patenting issues round off the book. As a result the book helps overcoming the challenges of using these materials in the pharmaceutical industry. For pharmaceutical and medicinal chemists, materials scientists, clinical physicists, and pharmaceutical laboratories looking to make better and more potent pharmaceuticals.
Download or read book Sulfur Mediated Rearrangements II written by Ernst Schaumann and published by Springer Science & Business Media. This book was released on 2007-03-15 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: With contributions by numerous experts
Download or read book Glycopeptides and Glycoproteins written by Valentin Wittmann and published by Springer. This book was released on 2007-01-30 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: With contributions by numerous experts
Download or read book Sulfur Mediated Rearrangements I written by Ernst Schaumann and published by Springer. This book was released on 2007-01-30 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Metal Catalyzed Reductive C C Bond Formation written by Michael J. Krische and published by Springer Science & Business Media. This book was released on 2007-07-20 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: TheprototypicalcatalyticreductiveC-Cbondformations,theFischer-Tropsch reaction [1] and alkene hydroformylation [2], were discovered in 1922 and 1938, respectively [3,4]. These processes, which involve reductive coupling to carbon monoxide, have long been applied to the industrial manufacture of commodity chemicals [5]. Notably, alkene hydroformylation, also known as the oxo-synthesis, has emerged as the largest volume application of homo- neous metal catalysis, accounting for the production of over 7 million metric tons of aldehyde annually. Despite the impact of these prototypical reductive C-C bond formations, this ?eld of research lay fallow for several decades. Eventually, the increased availability of mild terminal reductants, in part- ular silanes, led to a renaissance in the area of catalytic reductive C-C bond formation.Forexample,the'rstcatalyticreductiveC-Ccouplingsbeyond- droformylation, which involve the hydrosilylative dimerization of conjugated dienes [6-12], appeared in 1969 - approximately 16 years after the ?rst - ported metal-catalyzed alkene hydrosilylation [13]. Following these seminal studies, the ?eld of catalytic reductive C-C bond formation underwent exp- sivegrowth,culminatingintheemergenceofanevergrowingbodyofresearch encompassing a powerful set of transformations. To our knowledge, no thematic volumes devoted solely to metal-catalyzed reductive C-C bond formationhave been assembled. For the ?rst time, in this issue of Topics in Current Chemistry,wepresent acompilation ofmonographs from several leaders in this burgeoning area of research. This collection of reviews serves to capture the diversity of catalytic reductive C-C couplings presently available and, in turn, the remarkable range of reactivity embodied by such transformations. There is no indication that this ?eld has reached its zenithanditisthehopeofthepresentauthorthatthisvolumewillfuelfurther progress.
