Download or read book Novel Approaches to the Neuropharmacology of Mood Disorders written by Hector J. Carun and published by Frontiers Media SA. This book was released on 2019-10-24 with total page 111 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Ketamine for Treatment Resistant Depression written by Sanjay J. Mathew and published by Springer. This book was released on 2016-11-25 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings together an international group of clinicians and researchers from a broad swath of inter-related disciplines to offer the most up-to-date information about clinical and preclinical research into ketamine and second-generation “ketamine-like” fast-acting antidepressants. Currently available antidepressant medications act through monoaminergic systems, are ineffective for many individuals suffering from depression, and are associated with a delayed onset of peak efficacy of several months. The unexpected emergence of ketamine, an anesthetic N-methyl-D-aspartate (NMDA) receptor antagonist, as a rapid-acting antidepressant has reinvigorated CNS drug discovery research and catalyzed investigation in patient populations historically ignored in antidepressant drug development programs, particularly treatment-resistant patients and those with suicidality. Recent industry and academic research efforts have coalesced to explore NMDA receptor and glutamatergic molecular targets that lack ketamine’s psychotomimetic side effects and abuse liability but retain its rapid onset of efficacy. However, many fundamental questions remain regarding the neurobiological mechanisms underlying ketamine’s rapid antidepressant effects and the puzzling persistence of benefits observed in some patients following a single dose. This book examines how insights from these studies are forging new conceptual models of the neurobiology of stress-related affective, anxiety, and addictive disorders and the nature of treatment resistance. It also discusses how ketamine’s rapid antidepressant effects provide a scientific platform to facilitate innovation in clinical trial designs pertaining to patient selection, choice of control group, outcome measures, and dose-optimization. This book brings together data and insights from this rapidly expanding and extraordinarily promising field of study. Readers will be able to extract integrated themes and useful insights from the material contained in these diverse chapters and appreciate the paradigm-shifting contributions of ketamine to modern psychiatry and clinical neuroscience research.
Download or read book Charney Nestler s Neurobiology of Mental Illness written by Dennis S. Charney and published by Oxford University Press. This book was released on 2018 with total page 1025 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the years following publication of the DSM-5(R), the field of psychiatry has seen vigorous debate between the DSM's more traditional, diagnosis-oriented approach and the NIMH's more biological, dimension-based RDoC (research domain criteria) approach. Charney & Nestler's Neurobiology of Mental Illness is an authoritative foundation for translating information from the laboratory to clinical treatment, and its fifth edition extends beyond this reference function to acknowledge and examine the controversies, different camps, and thoughts on the future of psychiatric diagnosis. In this wider context, this book provides information from numerous levels of analysis, including molecular biology and genetics, cellular physiology, neuroanatomy, neuropharmacology, epidemiology, and behavior. Sections and chapters are edited and authored by experts at the top of their fields. No other book distills the basic science and underpinnings of mental disorders-and highlights practical clinical significance-to the scope and breadth of this classic text. In this edition, Section 1, which reviews the methods used to examine the biological basis of mental illness in animal and cell models and in humans, has been expanded to reflect critically important technical advances in complex genetics (including powerful sequencing technologies and related bioinformatics), epigenetics, stem cell biology, optogenetics, neural circuit functioning, cognitive neuroscience, and brain imaging. This range of established and emerging methodologies offer groundbreaking advances in our ability to study the brain as well as unique opportunities for the translation of preclinical and clinical research into badly needed breakthroughs in our therapeutic toolkit. Sections 2 through 7 cover the neurobiology and genetics of major psychiatric disorders: psychoses (including bipolar disorder), mood disorders, anxiety disorders, substance use disorders, dementias, and disorders of childhood onset. Also covered within these sections is a summary of current therapeutic approaches for these illnesses as well as the ways in which research advances are now guiding the search for new treatments. Each of these parts has been augmented in several different areas as a reflection of research progress. The last section, Section 8, reconfigured in this new edition, now focuses on diagnostic schemes for mental illness. This includes an overview of the unique challenges that remain in diagnosing these disorders given our still limited knowledge of disease etiology and pathophysiology. The section then provides reviews of DSM-5(R), which forms the basis of psychiatric diagnosis in the United States for all clinical work, and of RDoC, which provides an alternative perspective on diagnosis in heavy use in the research community. Also included are chapters on future efforts toward precision and computational psychiatry, which promise to someday align diagnosis with underlying biological abnormalities.
Download or read book Novel Approaches to Improve Detection Differentiation and Treatment in Mood Disorders written by Danilo Arnone and published by Frontiers Media SA. This book was released on 2022-03-28 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Neurobiological Basis of Suicide written by Yogesh Dwivedi and published by CRC Press. This book was released on 2012-06-25 with total page 485 pages. Available in PDF, EPUB and Kindle. Book excerpt: With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment and prevention strategies. The Neurobiological Basis of Suicide discusses the most recent findings in suicide neurobiology. Psychological, psychosocial, and cultural factors are important in determining the risk factors for suicide; however, they offer weak prediction and can be of little clinical use. Interestingly, cognitive characteristics are different among depressed suicidal and depressed nonsuicidal subjects, and could be involved in the development of suicidal behavior. The characterization of the neurobiological basis of suicide is in delineating the risk factors associated with suicide. The Neurobiological Basis of Suicide focuses on how and why these neurobiological factors are crucial in the pathogenic mechanisms of suicidal behavior and how these findings can be transformed into potential therapeutic applications.
Download or read book Neuropsychopharmacology written by Kenneth L. Davis and published by Lippincott Williams & Wilkins. This book was released on 2002 with total page 1964 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thoroughly updated and completely reorganized for a sharper clinical focus, the Fifth Edition of this world-renowned classic synthesizes the latest advances in basic neurobiology, biological psychiatry, and clinical neuropsychopharmacology. The book establishes a critical bridge connecting new discoveries in molecular and cellular biology, genetics, and neuroimaging with the etiology, diagnosis, and treatment of all neuropsychiatric disorders. Nine sections focus on specific groups of disorders, covering clinical course, genetics, neurobiology, neuroimaging, and current and emerging therapeutics. Four sections cover neurotransmitter and signal transduction, emerging methods in molecular biology and genetics, emerging imaging technologies and their psychiatric applications, and drug discovery and evaluation. Compatibility: BlackBerry(R) OS 4.1 or Higher / iPhone/iPod Touch 2.0 or Higher /Palm OS 3.5 or higher / Palm Pre Classic / Symbian S60, 3rd edition (Nokia) / Windows Mobile(TM) Pocket PC (all versions) / Windows Mobile Smartphone / Windows 98SE/2000/ME/XP/Vista/Tablet PC
Download or read book The 10 Best Ever Anxiety Management Techniques Understanding How Your Brain Makes You Anxious and What You Can Do to Change It Second written by Margaret Wehrenberg and published by W. W. Norton & Company. This book was released on 2018-02-27 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: A much-anticipated update to the classic personal road map, full of strategies to understand, manage, and conquer your stress. Do you feel a tightness in your chest and a racing heart anytime you have to speak up for yourself, whether in a large group or small? Does the very idea that others could perceive you as looking uncomfortable or frightened make those symptoms even worse? Do you vigilantly avoid potential panic triggers, and always think the worst is bound to happen? If so, you may be one of the 40 million Americans who suffer from anxiety. Symptoms run the gamut from mildly embarrassing but tolerable to persistent and debilitating. While feelings of worry, dread, panic, social unease, and general anxiety are common, their impact is insidious, leaving sufferers feeling worn out and often hopeless. This book is your answer. Drawing on fresh insights into the anatomy of the anxious brain, Dr. Wehrenberg gets to the biologically based heart of the problem and offers readers practical, effective tips to manage their anxiety on a day-to-day basis. From diaphragmatic breathing and self-talk, to mindfulness, muscle relaxation, and "plan to panic" strategies, you can learn to train your brain, conquer your stress and anxiety, and regain control of your life.
Download or read book Core Readings in Psychiatry written by Michael H. Sacks and published by American Psychiatric Pub. This book was released on 1995 with total page 1050 pages. Available in PDF, EPUB and Kindle. Book excerpt: Core Readings in Psychiatry, Second Edition, stands as an essential text for the academic. The contributors are distinguished experts who have a firm grasp of the relevant and classical citations in specific areas of psychiatry. In the intervening 8 years since the first edition, the profession's knowledge base has changed immensely. Included in this second edition are numerous citations and new topics such as AIDS, neuropsychiatry, models of psychoanalytic thought, child development, and medical economics. The book will open bibliographic doors for the academician as well as for the provider, manager, and consumer of psychiatric services and knowledge. It is designed to be an introduction and guide to the entire psychiatric literature.
Download or read book Cognitive Therapy for Bipolar Disorder written by Dominic H. Lam and published by John Wiley & Sons. This book was released on 2010-10-26 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: A thoroughly updated version of a key practitioner text, this new edition includes a treatment manual of cognitive-behavioural therapy for Bipolar Disorder which incorporates the very latest understanding of the psycho-social aspects of bipolar illness. Updated to reflect treatment packages developed by the authors over the last decade, and the successful completion of a large randomized controlled study which shows the efficacy of CBT for relapse prevention in Bipolar Disorder Demonstrates the positive results of a combined approach of cognitive behavioural therapy and medication Provides readers with a basic knowledge of bipolar disorders and its psycho-social aspects, treatments, and the authors’ model for psychological intervention Includes numerous clinical examples and case studies
Download or read book Phosphodiesterases CNS Functions and Diseases written by Han-Ting Zhang and published by Springer. This book was released on 2017-09-26 with total page 475 pages. Available in PDF, EPUB and Kindle. Book excerpt: PDEs are a family of enzymes that catalyze the hydrolysis of intracellular cyclic nucleotides. They are implicated in a number of disorders and dysfunctions and PDE inhibitors have already proven to be effective therapies for erectile dysfunction, COPD, and psoriatic arthritis. This family of enzymes also plays a role in diseases and disorders of the CNS such as depression, anxiety, schizophrenia, and Alzheimer's Disease. Unfortunately no effective PDE inhibitors have been developed for the treatment of these diseases. The proposed book will be a comprehensive overview of the current state of basic and translational research on PDE inhibitors written by internationally recognized experts. Authors will also discuss potential PDE subtypes and splice variants in the hopes that this will spur more creative approaches to PDE targeting drugs.
Download or read book Neurobiology of Mental Illness written by Dennis S. Charney and published by Oxford University Press, USA. This book was released on 2013-07-04 with total page 1259 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our understanding of the neurobiological basis of psychiatric disease has accelerated in the past five years. The fourth edition of Neurobiology of Mental Illness has been completely revamped given these advances and discoveries on the neurobiologic foundations of psychiatry. Like its predecessors the book begins with an overview of the basic science. The emerging technologies in Section 2 have been extensively redone to match the progress in the field including new chapters on the applications of stem cells, optogenetics, and image guided stimulation to our understanding and treatment of psychiatric disorders. Sections' 3 through 8 pertain to the major psychiatric syndromes-the psychoses, mood disorders, anxiety disorders, substance use disorders, dementias, and disorders of childhood-onset. Each of these sections includes our knowledge of their etiology, pathophysiology, and treatment. The final section discusses special topic areas including the neurobiology of sleep, resilience, social attachment, aggression, personality disorders and eating disorders. In all, there are 32 new chapters in this volume including unique insights on DSM-5, the Research Domain Criteria (RDoC) from NIMH, and a perspective on the continuing challenges of diagnosis given what we know of the brain and the mechanisms pertaining to mental illness. This book provides information from numerous levels of analysis including molecular biology and genetics, cellular physiology, neuroanatomy, neuropharmacology, epidemiology, and behavior. In doing so it translates information from the basic laboratory to the clinical laboratory and finally to clinical treatment. No other book distills the basic science and underpinnings of mental disorders and explains the clinical significance to the scope and breadth of this classic text. The result is an excellent and cutting-edge resource for psychiatric residents, psychiatric researchers and doctoral students in neurochemistry and the neurosciences.
Download or read book Rapid Acting Antidepressants written by and published by Academic Press. This book was released on 2020-06-29 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Advances in Pharmacology series presents a variety of chapters from the best authors in the field. - Includes the authority and expertise of leading contributors in pharmacology - Presents the latest release in the Advances in Pharmacology series
Download or read book Psychopharmacology Abstracts written by and published by . This book was released on 1974 with total page 850 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Psychiatric and Mental Health Nursing written by Ruth Elder and published by Elsevier Australia. This book was released on 2013 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt: The new edition of Psychiatric and Mental Health Nursing focuses on practice in mental health and psychiatric care integrating theory and the realities of practice. Mental wellness is featured as a concept, and the consideration of a range of psychosocial factors helps students contextualise mental illness and psychiatric disorders. The holistic approach helps the student and the beginning practitioner understand the complex causation of mental illness, its diagnosis, effective interventions and treatments, and the client's experience of mental illness.
Download or read book Mood Disorders written by Sudhakar Selvaraj and published by Cambridge University Press. This book was released on 2021-01-07 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offering up-to-date information on brain imaging in mood disorders, this book is an invaluable resource for mental health professionals.
Download or read book The Interactive World of Severe Mental Illness written by Diana J. Semmelhack and published by Routledge. This book was released on 2015-07-03 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: In our society, medication is often seen as the treatment for severe mental illness, with psychotherapy a secondary treatment. However, quality social interaction may be as important for the recovery of those with severe mental illness as are treatments. This volume makes this point while describing the emotionally moving lives of eight individuals with severe mental illness as they exist in the U.S. mental health system. Offering social and psychological insight into their experiences, these stories demonstrate how patients can create meaningful lives in the face of great difficulties. Based on in-depth interviews with clients with severe mental illness, this volume explores which structures of interaction encourage growth for people with severe mental illness, and which trigger psychological damage. It considers the clients’ relationships with friends, family, peers, spouses, lovers, co-workers, mental health professionals, institutions, the community, and the society as a whole. It focuses specifically on how structures of social interaction can promote or harm psychological growth, and how interaction dynamics affect the psychological well-being of individuals with severe mental illness.
Download or read book The Bipolar Book written by Aysegul Yildiz and published by Oxford University Press. This book was released on 2015-05-22 with total page 710 pages. Available in PDF, EPUB and Kindle. Book excerpt: As a major mainstay of clinical focus and research today, bipolar disorder affects millions of individuals across the globe with its extreme and erratic shifts of mood, thinking and behavior. Edited by a team of experts in the field, The Bipolar Book: History, Neurobiology, and Treatment is a testament and guide to diagnosing and treating this exceedingly complex, highly prevalent disease. Featuring 45 chapters from an expert team of contributors from around the world, The Bipolar Book delves deep into the origins of the disorder and how it informs clinical practice today by focusing on such topics as bipolar disorder occurring in special populations, stigmatization of the disease, the role genetics play, postmortem studies, psychotherapy, treatments and more. Designed to be the definitive reference volume for clinicians, students and researchers, Aysegül Yildiz, Pedro Ruiz and Charles Nemeroff present The Bipolar Book as a "must have" for those caregivers who routinely deal with this devastating disease.
