Download or read book New Insights on Biofilm Antimicrobial Strategies 2nd Volume written by Andreia S. Azevedo and published by Mdpi AG. This book was released on 2022-07-27 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In biofilms, microorganisms are able to communicate together and assemble by themselves, creating a consortium with different properties from the original free-floating microorganisms. In fact, biofilm cells bind strongly to a living or non-living surface, enclosed in a self-produced extracellular matrix that is composed of extracellular polymeric substances. One benefit of this lifestyle is the increased resistance or tolerance to antimicrobial agents (e.g., antibiotics). Hence, research on the development of alternative strategies to prevent and control biofilms is highly relevant for society in terms of human health, industry and the environment. Different approaches to prevent or control biofilms using antibiotic alternative strategies were submitted to this Special Issue.
Download or read book New Insights on Biofilm Antimicrobial Strategies written by Luís Melo and published by MDPI. This book was released on 2021-08-17 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last few decades, the study of microbial biofilms has been gaining interest among the scientific community. These microbial communities comprise cells adhered to surfaces that are surrounded by a self-produced exopolymeric matrix that protects biofilm cells against different external stresses. Biofilms can have a negative impact on different sectors within society, namely in agriculture, food industries, and veterinary and human health. As a consequence of their metabolic state and matrix protection, biofilm cells are very difficult to tackle with antibiotics or chemical disinfectants. Due to this problem, recent advances in the development of antibiotic alternatives or complementary strategies to prevent or control biofilms have been reported. This book includes different strategies to prevent biofilm formation or to control biofilm development and includes full research articles, reviews, a communication, and a perspective.
Download or read book New Insights on Biofilm Antimicrobial Strategies written by Luís Melo and published by . This book was released on 2021 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last few decades, the study of microbial biofilms has been gaining interest among the scientific community. These microbial communities comprise cells adhered to surfaces that are surrounded by a self-produced exopolymeric matrix that protects biofilm cells against different external stresses. Biofilms can have a negative impact on different sectors within society, namely in agriculture, food industries, and veterinary and human health. As a consequence of their metabolic state and matrix protection, biofilm cells are very difficult to tackle with antibiotics or chemical disinfectants. Due to this problem, recent advances in the development of antibiotic alternatives or complementary strategies to prevent or control biofilms have been reported. This book includes different strategies to prevent biofilm formation or to control biofilm development and includes full research articles, reviews, a communication, and a perspective.
Download or read book Bacterial Biofilms written by Tony Romeo and published by Springer Science & Business Media. This book was released on 2008-02-26 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: Throughout the biological world, bacteria thrive predominantly in surface-attached, matrix-enclosed, multicellular communities or biofilms, as opposed to isolated planktonic cells. This choice of lifestyle is not trivial, as it involves major shifts in the use of genetic information and cellular energy, and has profound consequences for bacterial physiology and survival. Growth within a biofilm can thwart immune function and antibiotic therapy and thereby complicate the treatment of infectious diseases, especially chronic and foreign device-associated infections. Modern studies of many important biofilms have advanced well beyond the descriptive stage, and have begun to provide molecular details of the structural, biochemical, and genetic processes that drive biofilm formation and its dispersion. There is much diversity in the details of biofilm development among various species, but there are also commonalities. In most species, environmental and nutritional conditions greatly influence biofilm development. Similar kinds of adhesive molecules often promote biofilm formation in diverse species. Signaling and regulatory processes that drive biofilm development are often conserved, especially among related bacteria. Knowledge of such processes holds great promise for efforts to control biofilm growth and combat biofilm-associated infections. This volume focuses on the biology of biofilms that affect human disease, although it is by no means comprehensive. It opens with chapters that provide the reader with current perspectives on biofilm development, physiology, environmental, and regulatory effects, the role of quorum sensing, and resistance/phenotypic persistence to antimicrobial agents during biofilm growth.
Download or read book Antibiofilm Agents written by Kendra P. Rumbaugh and published by Springer Science & Business Media. This book was released on 2014-05-08 with total page 495 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a survey of recent advances in the development of antibiofilm agents for clinical and environmental applications. The fact that microbes exist in structured communities called biofilms has slowly become accepted within the medical community. We now know that over 80% of all infectious diseases are biofilm-related; however, significant challenges still lie in our ability to diagnose and treat these extremely recalcitrant infections. Written by experts from around the globe, this book offers a valuable resource for medical professionals seeking to treat biofilm-related disease, academic and industry researchers interested in drug discovery and instructors who teach courses on microbial pathogenesis and medical microbiology.
Download or read book Mathematical Modeling of Biofilms written by IWA Task Group on Biofilm Modeling and published by IWA Publishing. This book was released on 2006-04-30 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over 90% of bacterial biomass exists in the form of biofilms. The ability of bacteria to attach to surfaces and to form biofilms often is an important competitive advantage for them over bacteria growing in suspension. Some biofilms are "good" in natural and engineered systems; they are responsible for nutrient cycling in nature and are used to purify waters in engineering processes. Other biofilms are "bad" when they cause fouling and infections of humans and plants. Whether we want to promote good biofilms or eliminate bad biofilms, we need to understand how they work and what works to control them. Mathematical Modeling of Biofilms provides guidelines for the selection and use of mathematical models of biofilms. The whole range of existing models - from simple analytical expressions to complex numerical models - is covered. The application of the models for the solution of typical problems is demonstrated, and the performance of the models is tested in comparative studies. With the dramatic evolution of the computational capacity still going on, modeling tools for research and practice will become more and more significant in the next few years. This report provides the foundation to understand the models and to select the most appropriate one for a given use. Mathematical Modeling of Biofilms gives a state-of-the-art overview that is especially valuable for educating students, new biofilm researchers, and design engineers. Through a series of three benchmark problems, the report demonstrates how to use the different models and indicates when simple or highly complex models are most appropriate. This is the first report to give a quantitative comparison of existing biofilm models. The report supports model-based design of biofilm reactors. The report can be used as basis for teaching biofilm-system modeling. The report provides the foundation for researchers seeking to use biofilm modeling or to develop new biofilm models. Scientific and Technical Report No.18
Download or read book Biofilm Infections written by Thomas Bjarnsholt and published by Springer. This book was released on 2014-10-11 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will cover both the evidence for biofilms in many chronic bacterial infections as well as the problems facing these infections such as diagnostics and treatment regimes. A still increasing interest and emphasis on the sessile bacterial lifestyle biofilms has been seen since it was realized that that less than 0.1% of the total microbial biomass lives in the planktonic mode of growth. The term was coined in 1978 by Costerton et al. who defined the term biofilm for the first time.In 1993 the American Society for Microbiology (ASM) recognised that the biofilmmode of growth was relevant to microbiology. Lately many articles have been published on the clinical implications of bacterial biofilms. Both original articles and reviews concerning the biofilm problem are available.
Download or read book Bacterial Biofilms written by Sadik Dincer and published by BoD – Books on Demand. This book was released on 2020-10-07 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines biofilms in nature. Organized into four parts, this book addresses biofilms in wastewater treatment, inhibition of biofilm formation, biofilms and infection, and ecology of biofilms. It is designed for clinicians, researchers, and industry professionals in the fields of microbiology, biotechnology, ecology, and medicine as well as graduate and postgraduate students.
Download or read book Biofilms in Wastewater Treatment written by Stefan Wuertz and published by IWA Publishing. This book was released on 2003-04-30 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: The central theme of the book is the flow of information from experimental approaches in biofilm research to simulation and modeling of complex wastewater systems. Probably the greatest challenge in wastewater research lies in using the methods and the results obtained in one scientific discipline to design intelligent experiments in other disciplines, and eventually to improve the knowledge base the practitioner needs to run wastewater treatment plants. The purpose of Biofilms in Wastewater Treatment is to provide engineers with the knowledge needed to apply the new insights gained by researchers. The authors provide an authoritative insight into the function of biofilms on a technical and on a lab-scale, cover some of the exciting new basic microbiological and wastewater engineering research involving molecular biology techniques and microscopy, and discuss recent attempts to predict the development of biofilms. This book is divided into 3 sections: Modeling and Simulation; Architecture, Population Structure and Function; and From Fundamentals to Practical Application, which all start with a scientific question. Individual chapters attempt to answer the question and present different angles of looking at problems. In addition there is an extensive glossary to familiarize the non-expert with unfamiliar terminology used by microbiologists and computational scientists. The colour plate section of this book can be downloaded by clicking here. (PDF Format 1 MB)
Download or read book Biofilm Highlights written by Hans-Curt Flemming and published by Springer Science & Business Media. This book was released on 2011-08-02 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: Living in biofilms is the common way of life of microorganisms, transiently immobilized in their matrix of extracellular polymeric substances (EPS), interacting in many ways and using the matrix as an external digestion and protection system. This is how they have organized their life in the environment, in the medical context and in technical systems – and has helped make them the oldest, most successful and ubiquitous form of life. In this book, hot spots in current biofilm research are presented in critical and sometimes provocative chapters. This serves a twofold purpose: to provide an overview and to inspire further discussions. Above all, the book seeks to stimulate lateral thinking.
Download or read book Streptococcus spp and Corynebacterium spp Clinical and Zoonotic Epidemiology Virulence Potential Antimicrobial Resistance and Genomic Trends and Approaches 2nd edition written by Prescilla Emy Nagao and published by Frontiers Media SA. This book was released on with total page 143 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Social Biology of Microbial Communities written by Institute of Medicine and published by National Academies Press. This book was released on 2013-01-10 with total page 633 pages. Available in PDF, EPUB and Kindle. Book excerpt: Beginning with the germ theory of disease in the 19th century and extending through most of the 20th century, microbes were believed to live their lives as solitary, unicellular, disease-causing organisms . This perception stemmed from the focus of most investigators on organisms that could be grown in the laboratory as cellular monocultures, often dispersed in liquid, and under ambient conditions of temperature, lighting, and humidity. Most such inquiries were designed to identify microbial pathogens by satisfying Koch's postulates.3 This pathogen-centric approach to the study of microorganisms produced a metaphorical "war" against these microbial invaders waged with antibiotic therapies, while simultaneously obscuring the dynamic relationships that exist among and between host organisms and their associated microorganisms-only a tiny fraction of which act as pathogens. Despite their obvious importance, very little is actually known about the processes and factors that influence the assembly, function, and stability of microbial communities. Gaining this knowledge will require a seismic shift away from the study of individual microbes in isolation to inquiries into the nature of diverse and often complex microbial communities, the forces that shape them, and their relationships with other communities and organisms, including their multicellular hosts. On March 6 and 7, 2012, the Institute of Medicine's (IOM's) Forum on Microbial Threats hosted a public workshop to explore the emerging science of the "social biology" of microbial communities. Workshop presentations and discussions embraced a wide spectrum of topics, experimental systems, and theoretical perspectives representative of the current, multifaceted exploration of the microbial frontier. Participants discussed ecological, evolutionary, and genetic factors contributing to the assembly, function, and stability of microbial communities; how microbial communities adapt and respond to environmental stimuli; theoretical and experimental approaches to advance this nascent field; and potential applications of knowledge gained from the study of microbial communities for the improvement of human, animal, plant, and ecosystem health and toward a deeper understanding of microbial diversity and evolution. The Social Biology of Microbial Communities: Workshop Summary further explains the happenings of the workshop.
Download or read book Type IV Secretion in Gram Negative and Gram Positive Bacteria written by Steffen Backert and published by Springer. This book was released on 2018-03-13 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Type IV secretion systems (T4SSs) are highly versatile membrane-associated transporter machines used by Gram-negative and Gram-positive bacteria to deliver substrate molecules to a large variety of target cells. This volume summarizes our current knowledge of the large variety and structural diversity of T4SSs in pathogenic Escherichia, Agrobacterium, Legionella, Coxiella, Bartonella, Helicobacter, Enterococcus and other species. Divided into 13 chapters contributed by leading experts, it presents findings that significantly enhance our understanding of how various pathogens manipulate host cell functions to trigger bacterial uptake, promote intracellular growth, suppress defense mechanisms and of how bacteria spread antibiotic resistances, thus facilitating bacterial colonization and disease development. The book is an invaluable source of information for researchers and clinicians.
Download or read book Biofilms and Veterinary Medicine written by Steven L. Percival and published by Springer Science & Business Media. This book was released on 2011-08-08 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biofilms are implicated in many common medical problems including urinary tract infections, catheter infections, middle-ear infections, dental plaque, gingivitis, and some less common but more lethal processes such as endocarditis and infections in cystic fibrosis. However, the true importance of biofilms in the overall process of disease pathogenesis has only recently been recognized. Bacterial biofilms are one of the fundamental reasons for incipient wound healing failure in that they may impair natural cutaneous wound healing and reduce topical antimicrobial efficiency in infected skin wounds. Their existence explains many of the enigmas of microbial infection and a better grasp of the process may well serve to establish a different approach to infection control and management. Biofilms and their associated complications have been found to be involved in up to 80% of all infections. A large number of studies targeted at the bacterial biofilms have been conducted, and many of them are referred to in this book, which is the first of its kind. These clinical observations emphasize the importance of biofilm formation to both superficial and systemic infections, and the inability of current antimicrobial therapies to ‘cure’ the resulting diseases even when the in vitro tests suggest that they should be fully effective. In veterinary medicine the concept of biofilms and their role in the pathogenesis of disease has lagged seriously behind that in human medicine. This is all the more extraordinary when one considers that much of the research has been carried out using veterinary species in experimental situations. The clinical features of biofilms in human medicine is certainly mimicked in the veterinary species but there is an inherent and highly regrettable indifference to the failure of antimicrobial therapy in many veterinary disease situations, and this is probably at its most retrograde in veterinary wound management. Biofilms and Veterinary Medicine is specifically focused on discussing the concerns of biofilms to health and disease in animals and provides a definitive text for veterinary practitioners, medical and veterinary students, and researchers.
Download or read book Desk Encyclopedia of Microbiology written by Moselio Schaechter and published by Academic Press. This book was released on 2010-04-19 with total page 1277 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Desk Encyclopedia of Microbiology, Second Edition is a single-volume comprehensive guide to microbiology for the advanced reader. Derived from the six volume e-only Encyclopedia of Microbiology, Third Edition, it bridges the gap between introductory texts and specialized reviews. Covering topics ranging from the basic science of microbiology to the current "hot" topics in the field, it will be invaluable for obtaining background information on a broad range of microbiological topics, preparing lectures and preparing grant applications and reports. The most comprehensive single-volume source providing an overview of microbiology to non-specialists Bridges the gap between introductory texts and specialized reviews Provides concise and general overviews of important topics within the field making it a helpful resource when preparing for lectures, writing reports, or drafting grant applications
Download or read book Microbial Biofilms written by Dharumadurai Dhanasekaran and published by BoD – Books on Demand. This book was released on 2016-07-13 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the book Microbial Biofilms: Importance and applications, eminent scientists provide an up-to-date review of the present and future trends on biofilm-related research. This book is divided with four subdivisions as biofilm fundamentals, applications, health aspects, and their control. Moreover, this book also provides a comprehensive account on microbial interactions in biofilms, pyocyanin, and extracellular DNA in facilitating Pseudomonas aeruginosa biofilm formation, atomic force microscopic studies of biofilms, and biofilms in beverage industry. The book comprises a total of 21 chapters from valued contributions from world leading experts in Australia, Bulgaria, Canada, China, Serbia, Germany, Italy, Japan, the United Kingdom, the Kingdom of Saudi Arabia, Republic of Korea, Mexico, Poland, Portugal, and Turkey. This book may be used as a text or reference for everyone interested in biofilms and their applications. It is also highly recommended for environmental microbiologists, soil scientists, medical microbiologists, bioremediation experts, and microbiologists working in biocorrosion, biofouling, biodegradation, water microbiology, quorum sensing, and many other related areas. Scientists in academia, research laboratories, and industry will also find it of interest.
Download or read book Secondary Metabolites in Soil Ecology written by Petr Karlovsky and published by Springer Science & Business Media. This book was released on 2008-01-03 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbiologists and soil scientists will find this study compelling reading. It focuses on the role of bacterial, fungal and plant secondary metabolites in soil ecosystems. Our understanding of the biological function of secondary metabolites is surprisingly limited, considering our knowledge of their structural diversity and pharmaceutical activity. This book reviews functional aspects of secondary metabolite production, with a focus on interactions among soil organisms.