Download or read book Neuroimaging Genetics written by Kristin L. Bigos and published by Oxford University Press. This book was released on 2016-02-03 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of neuroimaging genetics has grown exponentially over the past decade. To date there are more than 10,000 published papers involving MRI, PET, MEG and genetics. Neuroimaging Genetics: Principles and Practices is the comprehensive volume edited by Drs. Bigos, Hariri, and Weinberger and co-authored by the preeminent scholars in the field. This text reviews the basic principles of neuroimaging techniques and their application to neuroimaging genetics. The work presented in this volume elaborates on the explosive interest from diverse research areas in psychiatry and neurology in the use of imaging genetics as a unique tool to establish and identify mechanisms of risk, establish biological significance, and extend statistical evidence of genetic associations. Examples throughout highlight the application of imaging genetics to understand neurochemical systems and pathways, explore relationships between genetics and the structural and functional connectivity in human brain, and provide insight into mechanisms of risk for psychiatric and neurologic illness.
Download or read book Neuroimaging in Schizophrenia written by Marek Kubicki and published by Springer Nature. This book was released on 2020-02-18 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive book explains the importance of imaging techniques in exploring and understanding the role of brain abnormalities in schizophrenia. The findings obtained using individual imaging modalities and their biological interpretation are reviewed in detail, and updates are provided on methodology, testable hypotheses, limitations, and new directions for research. The coverage also includes important recent applications of neuroimaging to schizophrenia, for example in relation to non-pharmacological interventions, brain development, genetics, and prediction of treatment response and outcome. Written by world renowned experts in the field, the book will be invaluable to all who wish to learn about the newest and most important developments in neuroimaging research in schizophrenia, how these developments relate to the last 30 years of research, and how they can be leveraged to bring us closer to a cure for this devastating disorder. Neuroimaging in Schizophrenia will assist clinicians in navigating what is an extremely complex field and will be a source of insight and stimulation for researchers.
Download or read book The Bipolar Brain written by Stephen Strakowski and published by Oxford University Press. This book was released on 2022 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Although efforts to examine the structure and function of the human brain stretch back centuries (Paluzzi et al, 2007), techniques allowing the study of living humans are a relatively recent development. Early investigators confined themselves to largely studying external features, with 18th century methodologies such as phrenology purporting to link extracranial proxies for brain size and structure to specific personality traits (Livianos-Aldana et al, 2007). However, these techniques did not prove useful for either clinical or research purposes. Two-dimensional x-ray imaging, while constituting an important medical advance, did not provide sufficient soft tissue contrast to be useful for studying "functional" psychiatric disorders such as bipolar disorder; techniques to enhance contrast, such as ventriculography and pneumoencephalography were similarly limited (Figure 1.1). Wide-spread in vivo studies of brain morphometry had to await the development of computed tomography imaging (CT) in the early 1970s. By the early 1980s CT was already being applied to the study of bipolar disorder (Pearlson et al, 1981)"--
Download or read book Genetic Patterns in Neuroimaging An Issue of Neuroimaging Clinics written by Luis Celso Hygino de Cruz and published by Elsevier Health Sciences. This book was released on 2014-12-27 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic Patterns in Neuroimaging is explored in this important Neuroimaging Clinics issue. Articles include: Brain imaging and genetic risk of congenital malformations; Understanding genetics in neuroimaging; Influence of genetics in neuropathology; Building a bridge between genomics and neuroradiology; Systems genetics approaches to neuroimaging phenotypes; Imaging genetic predictions at an individual level; Brain imaging and genetic risk in the pediatric population; Imaging phenotypes in cognitive diseases; Molecular imaging in genetics; Imaging phenotypes in psychiatric disease; Genomics of brain tumor imaging; Neuroimaging and genetic influence in post-treatment brain neoplasms; Imaging phenotypes in multiple sclerosis; Genetic markers and influences in cerebrovascular malformations, and more.
Download or read book Imaging Genetics written by Adrian Dalca and published by Academic Press. This book was released on 2017-09-22 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: Imaging Genetics presents the latest research in imaging genetics methodology for discovering new associations between imaging and genetic variables, providing an overview of the state-of the-art in the field. Edited and written by leading researchers, this book is a beneficial reference for students and researchers, both new and experienced, in this growing area. The field of imaging genetics studies the relationships between DNA variation and measurements derived from anatomical or functional imaging data, often in the context of a disorder. While traditional genetic analyses rely on classical phenotypes like clinical symptoms, imaging genetics can offer richer insights into underlying, complex biological mechanisms. Contains an introduction describing how the field has evolved to the present, together with perspectives on its future direction and challenges Describes novel application domains and analytic methods that represent the state-of-the-art in the burgeoning field of imaging genetics Introduces a novel, large-scale analytic framework that involves multi-site, image-wide, genome-wide associations
Download or read book Psychiatric Neuroimaging written by Virginia Ng and published by IOS Press. This book was released on 2003 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Micro Meso and Macro Connectomics of the Brain written by Henry Kennedy and published by Springer. This book was released on 2016-03-10 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book has brought together leading investigators who work in the new arena of brain connectomics. This includes ‘macro-connectome’ efforts to comprehensively chart long-distance pathways and functional networks; ‘micro-connectome’ efforts to identify every neuron, axon, dendrite, synapse, and glial process within restricted brain regions; and ‘meso-connectome’ efforts to systematically map both local and long-distance connections using anatomical tracers. This book highlights cutting-edge methods that can accelerate progress in elucidating static ‘hard-wired’ circuits of the brain as well as dynamic interactions that are vital for brain function. The power of connectomic approaches in characterizing abnormal circuits in the many brain disorders that afflict humankind is considered. Experts in computational neuroscience and network theory provide perspectives needed for synthesizing across different scales in space and time. Altogether, this book provides an integrated view of the challenges and opportunities in deciphering brain circuits in health and disease.
Download or read book Neuroimaging in Addiction written by Bryon Adinoff and published by John Wiley & Sons. This book was released on 2011-11-02 with total page 539 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroimaging in Addiction presents an up-to-date, comprehensive review of the functional and structural imaging human studies that have greatly advanced our understanding of this complex disorder. Approaching addiction from a conceptual rather than a substance-specific perspective, this book integrates broad neuropsychological constructs that consider addiction as a neuroplastic process with genetic, developmental, and substance-induced contributions. The internationally recognized contributors to this volume are leaders in clinical imaging with expertise that spans the addiction spectrum. Following a general introduction, an overview of neural circuitry and modern non-invasive imaging techniques provides the framework for subsequent chapters on reward salience, craving, stress, impulsivity and cognition. Additional topics include the use of neuroimaging for the assessment of acute drug effects, drug-induced neurotoxicity, non-substance addictive behaviors, and the application of imaging genetics to identify unique intermediate phenotypes. The book concludes with an exploration of the future promise for functional imaging as guide to the diagnosis and treatment of addictive disorders. Scientists and clinicians will find the material in this volume invaluable in their work towards understanding the addicted brain, with the overall goal of improved prevention and treatment outcomes for patients. Features a Foreword by Edythe London, Director of the Center for Addictive Behaviors, University of California at Los Angeles.
Download or read book Neuroimaging Part B written by and published by Elsevier. This book was released on 2005-12-01 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprised of two separate volumes, Neuroimaging provides a state-of-the-art review of a broad range of neuroimaging techniques applied to both clinical and research settings. The breadth of the methods covered is matched by the depth of description of the theoretical background. Part B covers the application of neuroimaging in both research and clinical settings for the study of anxiety disorders, dementia, depression, schizophrenia, functional somatic syndromes, stroke, and multiple sclerosis using a range of neuroimaging modalities including CT, PET, SPECT, DTI, structural MRI and fMRI. One chapter is devoted to the study of brain development using structural MRI, and one chapter to the study of pediatric neurobehavioral disorders using fMRI. One of the most exciting recent applications of neuroimaging to the area of genetics is covered, and with the theory and application of neuroreceptor imaging in psychiatry, forms the final two chapters. The two parts of Neuroimaging complement each other providing in-depth information on a broad range of routine and cutting edge techniques that is not available in any other text. This book is superbly written and beautifully illustrated by contributors working at the top of their chosen specialty. Presents recent applications of neuroimaging to the area of genetics Discusses the study of brain development using structural MRI Includes chapters on the theory and application of neuroreceptor imaging in psychiatry
Download or read book Population Neuroscience written by Tomas Paus and published by Springer Science & Business Media. This book was released on 2013-03-23 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: Is Newton’s brain different from Rembrandt’s? Does a mother’s diet during pregnancy impact brain growth? Do adolescent peers leave a signature in the social brain? Does the way we live in our middle years affect how our brains age? To answer these and many other questions, we can now turn to population neuroscience. Population neuroscience endeavors to identify environmental and genetic factors that shape the function and structure of the human brain; it uses the tools and knowledge of genetics (and the “omics” sciences), epidemiology and neuroscience. This text attempts to provide a bridge spanning these three disciplines so that their practitioners can communicate easily with each other when working together on large-scale imaging studies of the developing, mature and aging brain. By understanding the processes driving variations in brain function and structure across individuals, we will also be able to predict an individual’s risk of (or resilience against) developing a brain disorder. In the long term, the hope is that population neuroscience will lay the foundation for personalized preventive medicine and, in turn, reduce the burden associated with complex, chronic disorders of brain and body.
Download or read book Neuroimaging in Psychiatry written by Cynthia H. Y. Fu and published by CRC Press. This book was released on 2003-09-26 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: New neuroimaging techniques are developing at a break neck pace-every academic journal contains glossy pictures of brain activity corresponding to a particular task emblazoned in glorious technicolor. Discoveries about brain function in psychiatric disorders have been made at an equally rapid rate. However, most books on the subject have been written from a technical point of view. An introductory, easy-to-read guide, Neuroimaging in Psychiatry provides an overview and the clinical relevance of the latest neuroimaging findings. With contributions from an international panel of experts, this book reviews current findings from neuroimaging in schizophrenia, obsessive-compulsive disorder, depression, eating disorders, psychopathy, aging, and drug addiction. Chapter authors explore innovative and imaginative uses of neuro imaging technology, implications for our understanding of these disorders, and their impact on clinical practice. The book gives you a general overview of the main techniques to help you successfully complete a neuroimaging project.
Download or read book Statistical Methods in Neuroimaging Genetics written by Matthew Silver and published by . This book was released on 2013 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Oxford Textbook of Neuroimaging written by Massimo Filippi and published by Oxford Textbooks in Clinical N. This book was released on 2015 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part of the Oxford Textbooks in Clinical Neurology series, the Oxford Textbook of Neuroimaging provides an overview of the established and latest neuroimaging methodologies, and illustrates their application to the main diseases of the brain and the spinal cord including movement disorders, headache and stroke. In addition, assessments of neuroimaging techniques in both adult and paediatric neurological conditions are included, enabling thorough examples from both age groups. This full-colour book contains 280 detailed photographs and illustrations that enable a clear understanding of each technique. Covering the newest advances, each different imagining technique is comprehensively described, providing a practical relevance and a stimulus for more in-depth readings. The print edition is supplemented with a concurrent online edition, which allows access to the full content of the textbook, contains links from the references to primary research journal articles, and provides access to figures and tables that can be downloaded by the user. Providing a balanced state-of-the-art guide to neuroimaging for neurologists and radiologists, this title will enhance understanding of the pathophysiological basis of neurological conditions and will help set the stage for future research.
Download or read book Neuroimaging in Developmental Clinical Neuroscience written by Judith M. Rumsey and published by Cambridge University Press. This book was released on 2009-02-19 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern neuroimaging offers tremendous opportunities for gaining insights into normative development and a wide array of developmental neuropsychiatric disorders. Focusing on ontogeny, this text covers basic processes involved in both healthy and atypical maturation, and also addresses the range of neuroimaging techniques most widely used for studying children. This book will enable you to understand normative structural and functional brain maturation and the mechanisms underlying basic developmental processes; become familiar with current knowledge and hypotheses concerning the neural bases of developmental neuropsychiatric disorders; and learn about neuroimaging techniques, including their unique strengths and limitations. Coverage includes normal developmental processes, atypical processing in developmental neuropsychiatric disorders, ethical issues, neuroimaging techniques and their integration with psychopharmacologic and molecular genetic research approaches, and future directions. This comprehensive volume is an essential resource for neurologists, neuropsychologists, psychiatrists, pediatricians, and radiologists concerned with normal development and developmental neuropsychiatric disorders.
Download or read book Graphs in Biomedical Image Analysis Computational Anatomy and Imaging Genetics written by M. Jorge Cardoso and published by Springer. This book was released on 2017-09-06 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed joint proceedings of the First International Workshop on Graphs in Biomedical Image Analysis, GRAIL 2017, the 6th International Workshop on Mathematical Foundations of Computational Anatomy, MFCA 2017, and the Third International Workshop on Imaging Genetics, MICGen 2017, held in conjunction with the 20th International Conference on Medical Imaging and Computer-Assisted Intervention, MICCAI 2017, in Québec City, QC, Canada, in September 2017. The 7 full papers presented at GRAIL 2017, the 10 full papers presented at MFCA 2017, and the 5 full papers presented at MICGen 2017 were carefully reviewed and selected. The GRAIL papers cover a wide range of graph based medical image analysis methods and applications, including probabilistic graphical models, neuroimaging using graph representations, machine learning for diagnosis prediction, and shape modeling. The MFCA papers deal with theoretical developments in non-linear image and surface registration in the context of computational anatomy. The MICGen papers cover topics in the field of medical genetics, computational biology and medical imaging.
Download or read book Neuroimaging in Dementia written by Frederik Barkhof and published by Springer Science & Business Media. This book was released on 2011-02-11 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: This up-to-date, superbly illustrated book is a practical guide to the effective use of neuroimaging in the patient with cognitive decline. It sets out the key clinical and imaging features of the various causes of dementia and directs the reader from clinical presentation to neuroimaging and on to an accurate diagnosis whenever possible. After an introductory chapter on the clinical background, the available "toolbox" of structural and functional neuroimaging techniques is reviewed in detail, including CT, MRI and advanced MR techniques, SPECT and PET, and image analysis methods. The imaging findings in normal ageing are then discussed, followed by a series of chapters that carefully present and analyze the key findings in patients with dementias. Throughout, a practical approach is adopted, geared specifically to the needs of clinicians (neurologists, radiologists, psychiatrists, geriatricians) working in the field of dementia, for whom this book will prove an invaluable resource.
Download or read book Handbook of Behavior Genetics written by Yong-Kyu Kim and published by Springer Science & Business Media. This book was released on 2009-03-25 with total page 557 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook provides research guidelines to study roles of the genes and other factors involved in a variety of complex behaviors. Utilizing methodologies and theories commonly used in behavior genetics, each chapter features an overview of the selected topic, current issues, as well as current and future research.
