Download or read book Stem Cell and Gene Based Therapy written by Alexander Battler and published by Springer Science & Business Media. This book was released on 2007-06-26 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: Regenerative medicine – stem cell and gene-based therapy – offers a new approach for restoring function of damaged organs and tissues. This is the first book to cover the major new aspects and field of regenerative medicine. This title is therefore a timely addition to the literature. It brings together the major approaches to regenerative medicine in one text, which ensures that techniques learnt in one discipline are disseminated across other areas of medicine.

Download or read book Regenerative Medicine Laboratory to Clinic written by Asok Mukhopadhyay and published by Springer. This book was released on 2017-09-21 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the two different cellular approaches that are pursued in regenerative medicine: cell therapy and tissue engineering. It examines in detail the therapeutic application of hematopoietic stem cells in marrow regeneration, multi-potent mesenchymal stem cells (MSCs), also referred to as mesenchymal stromal cells. The interest in MSCs can be seen in more than 150 clinical trials, some of which have progressed to Phase III, despite the cells’ limited differentiation potential. The book also explores how embryonic stem (ES) cells, being pluripotent in nature, can resolve some of the problems associated with adult stem cells, yet entail other challenges like risks of teratoma formation and immune rejection. A separate chapter deals with the role of noncoding RNAs in neuronal commitment of induced pluripotent stem (iPS) cells. Chapters like “Cord blood banking in India and the global scenario”; “3D bioprinting of tissue” and others will make this book an extremely interesting read for all students, researchers and clinicians working in the area of regenerative medicine/stem cells. The book is broadly divided into two parts, the first of which is devoted to basic information on stem cells, and the second of which addresses potential clinical applications in the areas of hematology, cardiology, orthopedic and immune suppression, etc.

Download or read book Essentials of Stem Cell Biology written by Robert Lanza and published by Academic Press. This book was released on 2013-08-31 with total page 685 pages. Available in PDF, EPUB and Kindle. Book excerpt: First developed as an accessible abridgement of the successful Handbook of Stem Cells, Essentials of Stem Cell Biology serves the needs of the evolving population of scientists, researchers, practitioners, and students embracing the latest advances in stem cells. Representing the combined effort of 7 editors and more than 200 scholars and scientists whose pioneering work has defined our understanding of stem cells, this book combines the prerequisites for a general understanding of adult and embryonic stem cells with a presentation by the world's experts of the latest research information about specific organ systems. From basic biology/mechanisms, early development, ectoderm, mesoderm, endoderm, and methods to the application of stem cells to specific human diseases, regulation and ethics, and patient perspectives, no topic in the field of stem cells is left uncovered. - Contributions by Nobel Laureates and leading international investigators - Includes two entirely new chapters devoted exclusively to induced pluripotent stem (iPS) cells written by the scientists who made the breakthrough - Edited by a world-renowned author and researcher to present a complete story of stem cells in research, in application, and as the subject of political debate - Presented in full color with a glossary, highlighted terms, and bibliographic entries replacing references

Download or read book Islet Transplantation and Beta Cell Replacement Therapy written by A. M. James Shapiro and published by CRC Press. This book was released on 2007-07-25 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: Beta cell replacement through transplantation remains the only treatment option for Type 1 diabetes enabling restoration of near-physiological glucose levels without significant hypoglycemia. Outlining the most recent advances and research breakthroughs, this practical guide and reference work explores the impact of islet cell transplantation and b

Download or read book Surgical Research written by Hans Troidl and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 685 pages. Available in PDF, EPUB and Kindle. Book excerpt: A unique reference manual for academic surgeons, this book discusses every facet of surgical research. From getting grant money to choosing a topic, reviewing the literature, planning and conducting research, and reporting results.

Download or read book Regenerative Medicine written by Gustav Steinhoff and published by Springer Science & Business Media. This book was released on 2013-03-20 with total page 1211 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of regenerative medicine has developed rapidly over the past 20 years with the advent of molecular and cellular techniques. This textbook, Regenerative Medicine: From Protocol to Patient, aims to explain the scientific knowledge and emerging technology as well as the clinical application in different organ systems and diseases. International leading experts from four continents describe the latest scientific and clinical knowledge of the field of regenerative medicine. The process of translating science of laboratory protocols into therapies is explained in sections on regulatory, ethical and industrial issues. This textbook is organized into five parts: (I) Biology of Tissue Regeneration, (II) Stem Cell Science and Technology, (III) Tissue Engineering, Biomaterials and Nanotechnology, (IV) Regenerative Therapies and (V) Regulation and Ethics. The textbook aims to give the student, the researcher, the health care professional, the physician and the patient a complete survey on the current scientific basis, therapeutical protocols, clinical translation and practiced therapies in regenerative medicine.

Download or read book Management of Pediatric Obesity and Diabetes written by Robert J. Ferry, Jr. and published by Springer Science & Business Media. This book was released on 2011-04-23 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: The twin epidemics of obesity and type 2 diabetes mellitus (T2DM) continue to affect an ever increasing number of children, adolescents, and young adults. Management of Pediatric Obesity and Diabetes provides healthcare trainees and professionals with practical, comprehensive, and contemporary approaches to the pediatric patient at risk for obesity, T2DM, and related conditions. A unique guide on the subject, this volume provides clinical paradigms for diagnosis and management of pediatric T2DM and related conditions, while succinctly describing state-of-the-art basic and clinical sciences underlying these problems. The chapters in this volume are independent and concise. Each chapter focuses on a key clinical issue or mechanism of disease. Providing practical, data-driven resources based upon the totality of the evidence, this important text helps the reader understand the basics of pediatric obesity and T2DM and implement strategies to prevent and treat obesity and diabetes in children and adolescents. Management of Pediatric Obesity and Diabetes provides health professionals across many areas of research and practice with up-to-date, well-referenced, and comprehensive evidence on identification, treatment, and prevention of these chronic, serious, metabolic diseases in children. This volume will serve the reader as the most authoritative resource in the field to date.

Download or read book Regenerative Medicine from Protocol to Patient written by Gustav Steinhoff and published by Springer. This book was released on 2016-06-14 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: ​Regenerative medicine is the main field of groundbreaking medical development and therapy using knowledge from developmental and stem cell biology as well as advanced molecular and cellular techniques. This collection of volumes on Regenerative Medicine: From Protocol to Patient, aims to explain the scientific knowledge and emerging technology as well as the clinical application in different organ systems and diseases. International leading experts from all over the world describe the latest scientific and clinical knowledge of the field of regenerative medicine. The process of translating science of laboratory protocols into therapies is explained in sections on regulatory, ethical and industrial issues. This collection is organized into five volumes: (1) Biology of Tissue Regeneration, (2) Stem Cell Science and Technology, (3) Tissue Engineering, Biomaterials and Nanotechnology, (4) Regenerative Therapies I, and (5) Regenerative Therapies II. The textbook gives the student, the researcher, the health care professional, the physician and the patient a complete survey on the current scientific basis, therapeutical protocols, clinical translation and practiced therapies in regenerative medicine. Volume 5 contains clinical science and translation surveys on the circulatory system, visceral, musculoskeletal and skin. The state-of-the-art descriptions involve concepts for clinical diagnosis, stem cell and gene therapy, biomaterials for tissue replacement and pharmacological/biomolecule treatment strategies.

Download or read book Handbook of Stem Cells written by Anthony Atala and published by Academic Press. This book was released on 2012-12-31 with total page 1076 pages. Available in PDF, EPUB and Kindle. Book excerpt: New discoveries in the field of stem cells increasingly dominate the news and scientific literature revealing an avalanche of new knowledge and research tools that are producing therapies for cancer, heart disease, diabetes, and a wide variety of other diseases that afflict humanity. The Handbook of Stem Cells integrates this exciting area of life science, combining in two volumes the requisites for a general understanding of adult and embryonic stem cells. Organized in two volumes entitled Pluripotent Stem Cells and Cell Biology and Adult and Fetal Stem Cells, this work contains contributions from the world's experts in stem cell research to provide a description of the tools, methods, and experimental protocols needed to study and characterize stem cells and progenitor populations as well as a the latest information of what is known about each specific organ system. - Provides comprehensive coverage on this highly topical subject - Contains contributions by the foremost authorities and premiere names in the field of stem cell research - Companion website - http://booksite.elsevier.com/9780123859426/ - contains over 250 color figures in presentation format

Download or read book Hair Follicle Regeneration written by Francisco Jimenez and published by Springer Nature. This book was released on 2022-06-03 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to comprehensively review the current cell-based strategies under investigation to achieve the regeneration of human hair follicles. The unique capacity of the human hair follicle to self-renew explains why this complex “mini-organ” has always attracted so much interest as a model for researchers to study stem cell biology and regenerative medicine. The hair follicle is considered a main reservoir of cutaneous stem cells, containing several pools of epithelial, melanocyte, and mesenchymal stem cells involved in hair follicle self-regeneration and pigmentation. In addition, while some of the different follicular cell types contribute to hair shaft growth, others participate in very important interfollicular functions such as dermal remodeling, re-epithelialization after wounding, and cutaneous stem cell homeostasis. The idea of human hair follicle regeneration either “de novo” or by activating dormant miniaturized follicles is not new, yet still continues to arouse enormous interest in the pursuit of a definitive cure for baldness. In contrast to hair follicle regeneration in mice, the attempts made with human follicles have been disappointing in terms of efficiency. However, recent advances in stem cell biology—as well as the appearance of new technologies like 3D printing—have revived expectations in this field of research. This book is divided into four sections. The first part includes an overview of the strategies used in hair follicle regeneration and a historical summary of the most important achievements to date. Parts two and three comprise the main body of the book, with detailed descriptions of the cells and tissue structures involved in hair follicle regeneration, followed by an elaboration of the different therapeutic strategies, engineering techniques, and a clinician’s perspective of stem cell-based therapies in hair loss treatments. Finally, the fourth part reviews the important contribution of the hair follicle in healing cutaneous wounds through the regeneration and remodeling of the dermis and epidermis after injury, as well as wound induced hair follicle neogenesis that occurs when the skin is injured.

Download or read book Pancreatic Hormones Advances in Research and Application 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 491 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pancreatic Hormones: Advances in Research and Application: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Pancreatic Hormones in a concise format. The editors have built Pancreatic Hormones: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Pancreatic Hormones in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Pancreatic Hormones: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Download or read book Sadikot s International Textbook of Diabetes written by Kamlakar Tripathi and published by Jaypee Brothers Medical Publishers. This book was released on 2019-04-30 with total page 1002 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a complete guide to the diagnosis and management of diabetes. Divided into eight sections, the text begins with an overview of the history, epidemiology and pathogenesis of the disease. The next chapters discuss different types diabetes, diagnosis, managements techniques, and monitoring. The following sections cover chronic and acute complications, and diabetes in special situations such as in pregnancy and during Ramadan. The book concludes with discussion on transplant, gene and stem cell therapy, psychosocial aspects, and public health and economics. The comprehensive text is further enhanced by clinical photographs, diagrams and exhaustive references. Key points Comprehensive guide to diagnosis and management of diabetes Covers different types of diabetes and potential complications Includes discussion on diabetes in special situations such as in pregnancy or during Ramadan Features clinical photographs, diagrams and exhaustive references

Download or read book ALERT Adverse Late Effects of Cancer Treatment written by Philip Rubin and published by Springer Science & Business Media. This book was released on 2013-10-04 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: The literature on the late effects of cancer treatment is widely scattered in different journals since all major organ systems are affected and management is based on a variety of medical and surgical treatments. The aim of "ALERT – Adverse Late Effects of Cancer Treatment" is to offer a coherent multidisciplinary approach to the care of cancer survivors. The Volume focuses on the general concepts and principles relevant to late effects and on the dynamic interplay of molecular, cytologic and histopathologic events that lead to altered physiologic and metabolic functions and their clinical manifestations. Chapters are also included on legal issues, economic aspects, nursing, psychological issues and quality of life. It is anticipated that this textbook will become the gold standard in providing information on the late effects of cancer treatment and that, in its digitized form, it will be referenced in cancer survivorship guidelines.

Download or read book Toxicology of the Pancreas written by Parviz M. Pour and published by CRC Press. This book was released on 2005-07-27 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: The increased incidence of pancreatic cancer in the Western world and its grave prognosis has resulted in an urgency for research in this area. Until now the available data on toxicology of the pancreas has been few and fragmentary, scattered throughout the literature. A benchmark volume, Toxicology of the Pancreas pulls together information in this neglected area of toxicological research and highlights fundamental research performed in the last ten years. Leaders in the field discuss important structures, the detoxification and toxification process at the cellular and sub-cellular level, the distribution of phase 1 and phase 2 drug-metabolizing enzymes and their role in pancreatic disease, and the role of diet and toxicants on pancreatic disease. The book also covers the role of altered genes in the integrity of the pancreas and explores comparative toxicology in humans and in the lab species used in testing. Illustrated with histological, electron microscopical, and immunohistochemical formats, this book provides a comprehensive and novel presentation of biological and toxicological data. It stands alone as a reliable resource of information easily accessible to professionals in different disciplines.

Download or read book Tertiary Lymphoid Structures from Basic Biology to Translational Impact in Cancer written by Vivek Verma and published by Frontiers Media SA. This book was released on 2022-04-06 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Fundamental Immunology written by William E. Paul and published by Lippincott Williams & Wilkins. This book was released on 2012-12-03 with total page 1313 pages. Available in PDF, EPUB and Kindle. Book excerpt: This standard-setting textbook has defined the field of immunology since 1984, and is now in its Seventh Edition continuing to deliver the detailed, authoritative, and timely coverage readers expect. This comprehensive, up-to-date text is ideal for graduate students, post-doctoral fellows, basic and clinical immunologists, microbiologists and infectious disease physicians, and any physician treating diseases in which immunologic mechanisms play a role. Now full-color throughout the book’s fully revised and updated content reflects the latest advances in the field. Current insights enhance readers’ understanding of immune system function. The text’s unique approach bridges the gap between basic immunology and the disease process. Extensive coverage of molecular biology explains the molecular dynamics underlying immune disorders and their treatment. Abundant illustrations and tables deliver essential information at a glance. Plus a convenient companion website features the fully searchable text and image bank! This is the tablet version of Fundamental Immunology which does not include access to the supplemental content mentioned in the text.

Download or read book Survivors of Childhood and Adolescent Cancer written by Cindy L. Schwartz and published by Springer. This book was released on 2015-09-03 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive guide that will help medical professionals – pediatric oncologists, nurses, pediatricians, family practitioners, internists, radiation oncologists, surgeons – to understand and manage the long-term effects of treatment for childhood and adolescent cancer. The consequences of treatment are described for each organ system, with explanation of pathophysiology, clinical manifestations, detection and screening and management. Disease- and organ-based algorithms of care and tables designed to facilitate the assessment of late effects are highlights of the book and will assist in the provision of hands-on care that is up to date and geared to clinical need. Among the other topics addressed are stem cell transplantation, psychological care, legal issues, transition to adulthood and methodological issues in the study of survivorship care.