Download or read book Natural Products as Less Toxic Antitumoral Antiangiogenic Agents Compared to Synthetic Conventional Chemotherapy written by Cecilia Veronica Nunez and published by Frontiers Media SA. This book was released on 2022-11-24 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book New Approaches for the Discovery of Pharmacologically Active Natural Compounds written by José L. Medina-Franco and published by MDPI. This book was released on 2019-07-01 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: A major source of active compounds, natural products from different sources supply a large variety of molecules that have been approved for clinical use or used as the starting points of optimization programs. This book features nine papers (eight full articles and one review paper) written by more than 45 scientists from around the world. These papers illustrate the development and application of a broad range of computational and experimental techniques applied to natural product research. On behalf of the contributors to the book, our hope is that the research presented here contributes to advancements in the field, and encourages multidisciplinary teams, young scientists, and students to further advance in the discovery of pharmacologically-active natural compounds
Download or read book Treatment of Leukemia and Lymphoma written by David A. Scheinberg and published by Elsevier. This book was released on 2004-10-30 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: New Treatments of Leukemia and Lymphoma describes the most important advances in the therapy of hematopoietic cancers that have been derived from recent discoveries in cancer cell biology, kinase biochemistry, and immunology. Detailed descriptions of the large number of new and effective agents that have recently become available for the treatment of leukemias and lymphomas as well as an understanding of their mechanisms of action and their integration into current therapy are provided. A number of experimental drug reagents currently in clinical investigation are also discussed. The therapies include conventional anti-metabolites, monoclonal antibodies directed to cell surface receptors, antibodies tagged with toxins and radiopharmaceuticals, inhibitors of specific kinases, stem cell transplants, and engineered T-cells designed to selectively target hematopoietic cancers. The contents of the book will allow practitioners and investigators alike to understand what is current and state of the art as well as what to look for in the future. * Provides an up-to-date, state of the art discussion of a rapidly changing field * Great breadth covering conventional chemotherapeutic agents, biologic agents such as antibodies, novel small molecule inhibitors and genetically engineered cells * Written by international experts in each of the fields
Download or read book Anticancer Agents from Natural Products written by Gordon M. Cragg and published by CRC Press. This book was released on 2005-06-13 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plants, marine organisms, and microorganisms have evolved complex chemical defense and signaling systems that are designed to protect them from predators and provide other biological benefits. These organisms thus produce substances containing novel chemotypes that may have beneficial effects for humans. As collection methods improve and new screen
Download or read book Life Over Cancer written by Keith Block and published by Bantam. This book was released on 2009-04-21 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Keith Block is at the global vanguard of innovative cancer care. As medical director of the Block Center for Integrative Cancer Treatment in Evanston, Illinois, he has treated thousands of patients who have lived long, full lives beyond their original prognoses. Now he has distilled almost thirty years of experience into the first book that gives patients a systematic, research-based plan for developing the physical and emotional vitality they need to meet the demands of treatment and recovery. Based on a profound understanding of how body and mind can work together to defeat disease, this groundbreaking book offers: • Innovative approaches to conventional treatments, such as “chronotherapy”–chemotherapy timed to patients’ unique circadian rhythms for enhanced effectiveness and reduced toxicity • Dietary choices that make the biochemical environment hostile to cancer growth and recurrence, and strengthen the immune system’s ability to attack remaining cancer cells • Precise supplement protocols to tame treatment side effects, relieve disease-related symptoms, and modify processes like inflammation and glycemia that can fuel cancer if left untreated • A new paradigm for exercise and stress reduction that restores your strength, reduces anxiety and depression, and supports the body’s own ability to heal • A complete program for remission maintenance–a proactive plan to make sure the cancer never returns Also included are “quick-start” maps to help you find the information you need right now and many case histories that will support and inspire you. Encouraging, compassionate, and authoritative, Life over Cancer is the guide patients everywhere have been waiting for.
Download or read book Polysaccharide based Nano Biocarrier in Drug Delivery written by Tapan Kumar Giri and published by CRC Press. This book was released on 2018-09-03 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses various fundamental aspects of polysaccharide based nano-biocarrier drug delivery systems and its application in the delivery of small molecules, proteins, peptides, oligonucleotides and genes. It also discusses advances in drug delivery systems in treatment of cancer, cardiovascular, pulmonary, and infectious diseases.
Download or read book Chemoprevention of Cancer written by Daniel W. Nixon and published by CRC Press. This book was released on 1994-11-08 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemoprevention of Cancer guides you through the exciting new field of cancer chemoprevention. It covers epidemiology, known chemopreventive compounds, development of new chemopreventive agents, specific examples of preventive agents and their mechanisms of action, and current prevention clinical trials.
Download or read book Adverse Effects of Cancer Chemotherapy Anything New to Improve Tolerance and Reduce Sequelae written by Kulmira Nurgali and published by Frontiers Media SA. This book was released on 2018-06-12 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in anti-cancer chemotherapy over recent years have led to improved efficacy in curing or controlling many cancers. Some chemotherapy-related side-effects are well recognized and include: nausea, vomiting, bone marrow suppression, peripheral neuropathy, cardiac and skeletal muscle dysfunction and renal impairment. However, it is becoming clearer that some chemotherapy-related adverse effects may persist even in long term cancer survivors. Problems such as cognitive, cardiovascular and gastrointestinal dysfunction, and neuropathy may lead to substantial long term morbidity. Despite improvements in treatments to counteract acute chemotherapy-induced adverse effects, they are often incompletely effective. Furthermore, counter-measures for some acute side-effects and many potential longer term sequelae of anti-cancer chemotherapy have not been developed. Thus, new insights into prevalence and mechanisms of cancer chemotherapy-related side effects are needed and new approaches to improving tolerance and reduce sequelae of cancer chemotherapy are urgently needed. The present Research Topic focuses on adverse effects and sequelae of chemotherapy and strategies to counteract them.
Download or read book Marine Compounds and Cancer written by Friedemann Honecker and published by MDPI. This book was released on 2018-06-26 with total page 119 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue "Marine Compounds and Cancer" that was published in Marine Drugs
Download or read book Biological Activities of Alkaloids written by Sabino Aurelio Bufo and published by MDPI. This book was released on 2020-05-13 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural products are increasingly attracting attention from both basic and applied science. Plant secondary metabolites, especially alkaloids, are receiving interest from a wide range of researchers due to their biological activity. They are produced to protect plants from diseases and herbivores. Therefore, they reveal a toxic activity that affects organisms at various levels of biological organization. A growing amount of research is proving their antimicrobial, antifungal, insecticidal, and anticancer activities. That makes them applicable in various fields from medicine, to pharmacology, veterinary, and toxicology, to crop protection. This Special Issue of Toxins, “Biological Activities of Alkaloids: From Toxicology to Pharmacology", collects 15 manuscripts describing the ecological, biological, pharmacological, and toxicological effects as well as structural and analytical aspects of plant alkaloids, their mode of action, and possible application in veterinary, medicine, and plant protection. These studies prove the potential for alkaloid application in various areas of science.
Download or read book Natural Products for Cancer Prevention and Therapy written by Anupam Bishayee and published by MDPI. This book was released on 2018-11-07 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue "Natural Products for Cancer Prevention and Therapy" that was published in Nutrients
Download or read book Handbook of Anticancer Drugs from Marine Origin written by Se-Kwon Kim and published by Springer. This book was released on 2014-11-27 with total page 801 pages. Available in PDF, EPUB and Kindle. Book excerpt: This timely desk reference focuses on marine-derived bioactive substances which have biological, medical and industrial applications. The medicinal value of these marine natural products are assessed and discussed. Their function as a new and important resource in novel, anticancer drug discovery research is also presented in international contributions from several research groups. For example, the potential role of Spongistatin, Apratoxin A, Eribulin mesylate, phlorotannins, fucoidan, as anticancer agents is explained. The mechanism of action of bioactive compounds present in marine algae, bacteria, fungus, sponges, seaweeds and other marine animals and plants are illustrated via several mechanisms. In addition, this handbook lists various compounds that are active candidates in chemoprevention and their target actions. The handbook also places into context the demand for anticancer nutraceuticals and their use as potential anti-cancer pharmaceuticals and medicines. This study of advanced and future types of natural compounds from marine sources is written to facilitate the understanding of Biotechnology and its application to marine natural product drug discovery research.
Download or read book Medicinal Plants written by Bassam Hassan and published by BoD – Books on Demand. This book was released on 2020-03-25 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is focused on clarifying the anticancer effects (i.e., apoptotic, antiproliferative, antimetastatic, antiangiogenic) and mechanisms of most of the medicinal plants found in the world against solid and/or hematological cancers.
Download or read book Medicinal and Aromatic Plants written by Tariq Aftab and published by Springer Nature. This book was released on 2021-03-27 with total page 781 pages. Available in PDF, EPUB and Kindle. Book excerpt: Before the concept of history began, humans undoubtedly acquired life benefits by discovering medicinal and aromatic plants (MAPs) that were food and medicine. Today, a variety of available herbs and spices are used and enjoyed throughout the world and continue to promote good health. The international market is also quite welcoming for MAPs and essential oils. The increasing environment and nature conscious buyers encourage producers to produce high quality essential oils. These consumer choices lead to growing preference for organic and herbal based products in the world market. As the benefits of medicinal and aromatic plants are recognized, these plants will have a special role for humans in the future. Until last century, the production of botanicals relies to a large degree on wild-collection. However, the increasing commercial collection, largely unmonitored trade, and habitat loss lead to an incomparably growing pressure on plant populations in the wild. Therefore, medicinal and aromatic plants are of high priority for conservation. Given the above, we bring forth a comprehensive volume, “Medicinal and Aromatic Plants: Healthcare and Industrial Applications”, highlighting the various healthcare, industrial and pharmaceutical applications that are being used on these immensely important MAPs and its future prospects. This collection of chapters from the different areas dealing with MAPs caters to the need of all those who are working or have interest in the above topic.
Download or read book Medicinal Chemistry of Anticancer Drugs written by Carmen Avendaño and published by Elsevier. This book was released on 2015-06-11 with total page 767 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicinal Chemistry of Anticancer Drugs, Second Edition, provides an updated treatment from the point of view of medicinal chemistry and drug design, focusing on the mechanism of action of antitumor drugs from the molecular level, and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents. Antitumor chemotherapy is a very active field of research, and a huge amount of information on the topic is generated every year. Cytotoxic chemotherapy is gradually being supplemented by a new generation of drugs that recognize specific targets on the surface or inside cancer cells, and resistance to antitumor drugs continues to be investigated. While these therapies are in their infancy, they hold promise of more effective therapies with fewer side effects. Although many books are available that deal with clinical aspects of cancer chemotherapy, this book provides a sorely needed update from the point of view of medicinal chemistry and drug design. Presents information in a clear and concise way using a large number of figures Historical background provides insights on how the process of drug discovery in the anticancer field has evolved Extensive references to primary literature
Download or read book Plants that Fight Cancer Second Edition written by Spyridon E. Kintzios and published by CRC Press. This book was released on 2019-06-26 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: An increasing amount of cancer research is being directed towards the investigation of plant-derived anticancer compounds, many of which have been used in traditional herbal treatments for centuries. Plants that Fight Cancer is an up-to-date, extensive review of plant genera and species with documented anti-tumor and anti-leukaemic properties. Following an overview of the disease and the diverse methods of therapy and clinical testing, the book provides a detailed examination of the plants whose compounds are currently used in conventional cancer treatment, the species which show the greatest potential as future candidates, and other species with established anticancer properties. The third section explores each of more than 150 terrestrial plant genera and species, with a review of their traditional uses, mythology, botany, active ingredients, and product applications, along with photographs and illustrations and an analysis of expected results and risks. The text closes with a discussion of algal extracts and isolated metabolites with anticancer activity, a summary of published research for each species, and chemical structures of the most important compounds.
Download or read book Immunotherapy of Hepatocellular Carcinoma written by Tim F. Greten and published by Springer. This book was released on 2018-08-22 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book we provide insights into liver – cancer and immunology. Experts in the field provide an overview over fundamental immunological questions in liver cancer and tumorimmunology, which form the base for immune based approaches in HCC, which gain increasing interest in the community due to first promising results obtained in early clinical trials. Hepatocellular carcinoma (HCC) is the third most common cause of cancer related death in the United States. Treatment options are limited. Viral hepatitis is one of the major risk factors for HCC, which represents a typical “inflammation-induced” cancer. Immune-based treatment approaches have revolutionized oncology in recent years. Various treatment strategies have received FDA approval including dendritic cell vaccination, for prostate cancer as well as immune checkpoint inhibition targeting the CTLA4 or the PD1/PDL1 axis in melanoma, lung, and kidney cancer. Additionally, cell based therapies (adoptive T cell therapy, CAR T cells and TCR transduced T cells) have demonstrated significant efficacy in patients with B cell malignancies and melanoma. Immune checkpoint inhibitors in particular have generated enormous excitement across the entire field of oncology, providing a significant benefit to a minority of patients.
