Download or read book Natural Product Treatment of Gastrointestinal Diseases 2nd edition written by Mingyu Sun and published by Frontiers Media SA. This book was released on 2023-07-18 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gastrointestinal (GI) cancers, including esophageal, gastric, and colorectal cancers, are one of the major malignant diseases detrimental to health and account for almost 20% of all cancers worldwide. Besides their high incidence, GI cancers are related to high mortality rates, placing these malignancies among the most prominent public health issues of our time. Gastrointestinal diseases are prevalent, especially functional gastrointestinal disorders. Natural product has been used for thousands of years in the treatment of gastrointestinal diseases including cancer. To discover and develop the natural product with therapeutic selectivity and without toxicity are very important steps in the treatment of GI diseases. Because of their wide range of pharmacologic activities and low toxicity in animal models, many natural products have been used as alternative treatments for gastrointestinal diseases and cancers. Growing evidence has shown that natural products are beneficial for patients with gastrointestinal diseases or cancer, but it is still unconvincing and the mechanism behind the effect has not been fully revealed. In this Research Topic, we emphasize: (1) evaluation of clinical effectiveness of natural products in the treatment of gastrointestinal diseases including cancer; (2) mechanism of action of natural products; (3) translation of natural products into routine practice.

Download or read book Herbal Antivirals 2nd Edition written by Stephen Harrod Buhner and published by Storey Publishing, LLC. This book was released on 2021-08-31 with total page 603 pages. Available in PDF, EPUB and Kindle. Book excerpt: Viruses are smart, mutating, and becoming resistant to antiviral pharmaceuticals. Global crises such as COVID-19, SARS, and dengue feaver spread more quickly than we can develop medicines to fight them. Herbalist and best-selling author Stephen Harrod Buhner has studied the antiviral properties of plants for many years. In this comprehensive guide, he profiles the plants that have proven most effective in fighting viral infections and provides in-depth instructions for preparing and using formulations to address the most common infections and strengthen immunity, safely and naturally. The updated 2nd edition includes an expanded guide to COVID-19, including a review of the most up-to-date medical research and the plant medicines that have been found to be most potent in preventing infection, lessening the impact of the virus on the body, and addressing longer-term effects and co-infections. This publication conforms to the EPUB Accessibility specification at WCAG 2.0 Level AA.

Download or read book Disease Control Priorities in Developing Countries written by Dean T. Jamison and published by World Bank Publications. This book was released on 2006-04-02 with total page 1449 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on careful analysis of burden of disease and the costs ofinterventions, this second edition of 'Disease Control Priorities in Developing Countries, 2nd edition' highlights achievable priorities; measures progresstoward providing efficient, equitable care; promotes cost-effectiveinterventions to targeted populations; and encourages integrated effortsto optimize health. Nearly 500 experts - scientists, epidemiologists, health economists,academicians, and public health practitioners - from around the worldcontributed to the data sources and methodologies, and identifiedchallenges and priorities, resulting in this integrated, comprehensivereference volume on the state of health in developing countries.

Download or read book Herbal Medicine written by Iris F. F. Benzie and published by CRC Press. This book was released on 2011-03-28 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: The global popularity of herbal supplements and the promise they hold in treating various disease states has caused an unprecedented interest in understanding the molecular basis of the biological activity of traditional remedies. Herbal Medicine: Biomolecular and Clinical Aspects focuses on presenting current scientific evidence of biomolecular ef

Download or read book Anticancer Agents from Natural Products Second Edition written by Gordon M. Cragg and published by CRC Press. This book was released on 2011-10-10 with total page 786 pages. Available in PDF, EPUB and Kindle. Book excerpt: The approach to drug discovery from natural sources has yielded many important new pharmaceuticals inaccessible by other routes. In many cases the isolated natural product may not be an effective drug for any of several reasons, but it nevertheless may become a drug through chemical modification or have a novel pharmacophore for future drug design. In summarizing the status of natural products as cancer chemotherapeutics, Anticancer Agents from Natural Products, Second Edition covers the: History of each covered drug—a discussion of its mechanism on action, medicinal chemistry, synthesis, and clinical applications Potential for novel drug discovery through the use of genome mining as well as future developments in anticancer drug discovery Important biosynthetic approaches to "unnatural" natural products Anticancer Agents from Natural Products, Second Edition discusses how complex target-oriented synthesis—enabled by historic advances in methodology—has enormously expanded the scope of the possible. This book covers the current clinically used anticancer agents that are either natural products or are clearly derived from natural product leads. It also reviews drug candidates currently in clinical development since many of these will be clinically used drugs in the future. Examples include the drugs etoposide and teniposide derived from the lead compound podophyllotoxin; numerous analogs derived from taxol; topotecan, derived from camptothecin; and the synthetic clinical candidates, E7389 and HTI-286, developed from the marine leads, halichondrin B and hemiasterlin.

Download or read book Handbook of African Medicinal Plants written by Maurice M. Iwu and published by CRC Press. This book was released on 2014-02-04 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: With over 50,000 distinct species in sub-Saharan Africa alone, the African continent is endowed with an enormous wealth of plant resources. While more than 25 percent of known species have been used for several centuries in traditional African medicine for the prevention and treatment of diseases, Africa remains a minor player in the global natural

Download or read book Multi targeted Natural Products as Cancer Therapeutics Challenges and Opportunities Volume I 2nd edition written by Jiang-Jiang Qin and published by Frontiers Media SA. This book was released on 2024-01-11 with total page 699 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Research Topic is part of a series with: Multi-targeted Natural Products as Cancer Therapeutics: Challenges and Opportunities, Volume II Cancer remains a leading cause of disease-related deaths worldwide, despite recent advances in our understanding of cancer initiation, progression, and metastasis. Chemotherapy and radiotherapy have been used as standard non-surgical treatments of human cancer for decades, however, the survival rates of patients with cancer, especially those with advanced diseases are still very low due to the high toxicities of these treatments as well as the severe side effects. This fact has motivated researchers to discover new cancer therapeutics with minimum side effects, which intensively promotes the rapid development of single specific molecule-targeted therapies (SSMTT). Many efforts have been made in world-wide cancer drug discovery research and several single molecule-targeted therapies have been successfully developed. Unfortunately, most of the investments failed because cancer is a genetic disease and always harbors multiple alternations of molecules or genes at the genomic, genetic and epigenetic levels. The inhibition of a single molecule or signaling pathway by SSMTT frequently results in a hyperactive compensation of other cancer-related molecules and signaling pathways as well as the subsequent development of drug resistance. Therefore, identifying multi-targeted therapies, i.e. drugs that are able to target multiple cancer-related genes, proteins, or signaling pathways is a more promising way to success in developing new cancer therapeutics. Natural products, especially those from traditional Chinese medicine and folk remedies in other countries are an extraordinarily important source for new drug discovery over the past decades. Of note, many natural products have often been demonstrated to target several crucial genes or proteins in cancer-related signaling networks and exert synergistic effects. For example, Japonicone A, a dimeric sesquiterpenoid from the medicinal plant Inula japonica, has been found to inhibit tumor growth and metastasis by dually targeting the TNF-α/NF-κB and p53/MDM2 signaling pathways. Traditionally, researchers have believed that the multi-targeting mechanisms of natural products have limited their use in cancer treatment due to the low specificity and potential side effects. The growing interest in developing multi-targeted cancer therapies may provide another golden opportunity to develop natural products as new cancer therapeutics. Nevertheless, critical investigations for a comprehensive understanding of the molecular mechanisms of natural products also mean more challenges. Our long-term goals are to fully understand the molecular targets and mechanisms of action of anticancer natural products and develop them as novel cancer preventive and therapeutic agents. The specific goal of this Research Topic is to bring together the recent findings of newly identified anticancer natural products, especially those with multiple molecular targets. Papers (Original Research articles or Reviews) which discuss the in vitro and in vivo efficacy and pharmacological and toxicological properties of natural products are also welcome to be submitted. Guidelines for the conception and review of submissions As many anticancer drugs working as cytotoxic compounds have non-selective effects annihilating their potential therapeutic benefits, manuscripts are advised to provide evidence of a significant selectivity towards cancer cells (vs. healthy cells). Specifically, if the studied anticancer drug or modality does not target an oncogenic pathway, the authors should make every effort possible to prove that the cytotoxic or cytostatic effects they have identified exhibit selectivity for cancer cells (ideally 1 log difference in EC50 or IC50) vs. non-malignant cells (eg, fibroblasts or primary culture of cells). The authors should also demonstrate the applicability of their anticancer modalities on a minimum of two well-authenticated cancer cell lines (ideally originating from distinct organs/tissues). For manuscripts dealing with plant extracts or other natural substances/compounds, the composition and the stability of the study material must be described in sufficient detail. In particular, for extracts, chromatograms with characterization of the dominating compound(s) are requested. The level of purity must be proven and included. Please refer to the Four Pillars of Best Practice in Ethnopharmacology, a subset of which concerning general standards in natural product research are applied to all such studies in all sections of Frontiers in Pharmacology.

Download or read book Herbal Medicines for Gastrointestinal and Hepatic Diseases Novel Pharmacological and Toxicological approaches Volume I 2nd edition written by Muhammad Hasnat, and published by Frontiers Media SA. This book was released on 2023-07-21 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Research Topic is part of a series with: Herbal Medicines for Gastrointestinal and Hepatic Diseases - Novel Pharmacological and Toxicological approaches, Volume II Ethnopharmacology deals with the exchange of knowledge about people's use of herbal medicines and their pharmacological effects. The information related to therapeutic agents of plant origin and their toxic effects was preserved by oral tradition as well as recorded in materia medica. Many drugs that are now available on the market have been developed from this valuable information. Today, scientists that specialize in medicinal chemistry use these existing herbal drugs to develop and produce more therapeutically active agents with less toxic side effects. The gastrointestinal tract (GIT) is a multi-organ system, consisting of bacteria, and digestive enzymes that have the capacity of degrading food and other molecules. Diseases associated with this organ system include peptic ulcer, inflammatory bowel disease, gastric cancer to name a few. The liver receives seventy percent of its blood supply from the GIT via the hepatic portal vein. The disruption in the gut–liver axis is associated with liver diseases including alcohol-associated liver disease (ALD), non-alcoholic fatty liver disease (NAFLD), and autoimmune liver disease (AILD). NAFLD can cause non-alcoholic steatohepatitis, which can develop into liver cirrhosis through inflammation and fibrosis. Liver cirrhosis is categorized as an end-stage of chronic liver disease, which impairs innate immunity-related genes. Growing evidence from preclinical studies proposes that the gut–liver axis leads to targeted therapeutic modalities for various liver injuries. Therefore, therapeutic treatment of these conditions is essential to prevent progression to these more harmful late-stage diseases.

Download or read book Encyclopedia of Gastroenterology written by and published by Academic Press. This book was released on 2019-11-06 with total page 3444 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encyclopedia of Gastroenterology, Second Edition, Four Volume Set provides a comprehensive and concise reference on all aspects of gastroenterology and hepatology, including the organs in the gastrointestinal system, their functions in health and disease, and strategies or procedures to resolve or prevent problems and disease. This concise, up-to-date information includes comprehensive sections on the impact of nutrition, gastrointestinal microbiota, lifestyle, commonly used drugs, and surgical procedures on health and disease. Since the first edition, attention to the roles of nutrition and gastrointestinal microorganisms (microbiota, formerly Microbiota) in health and disease has skyrocketed. In addition, an entirely new section on obesity and diabetes is included. Presents comprehensive coverage of every topic within gastroenterology Offers researchers a one-stop, fully-referenced resource to explore questions Includes teaching tools, multimedia and interactive elements Provides readers with multi-layered content and a media-rich learning resource for both instructors and students Covers hot new topics in GI health and disease, including new sections on stem cells, intestinal bacteria, obesity and intestinal microbiota

Download or read book Novel Natural Products Therapeutic Effects in Pain Arthritis and Gastro intestinal Diseases written by K. D. Rainsford and published by Springer. This book was released on 2015-07-30 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years there have been a number of significant developments of natural products for the treatment of rheumatic diseases, pain and gastro-intestinal ulcers and inflammation. The volume covers some of these novel developments of natural products which are of current and future interest as therapies for the above-mentioned conditions. Most available volumes cover a wide range of biological and technicological aspects of natural products and their discovery, some involving synthesis and properties of chemical compounds. The difference in this volume is that the natural products have a focus on their therapeutic effects on pain, arthritic and gastrointestinal diseases. Some of the natural products covered are either at the experimental stage of development while others are well-established clinically-used products. Each has its own unique place in therapy.

Download or read book Treatment of Voice Disorders Second Edition written by Robert Thayer Sataloff and published by Plural Publishing. This book was released on 2017-10-20 with total page 585 pages. Available in PDF, EPUB and Kindle. Book excerpt: Treatment of Voice Disorders, Second Edition presents the entire range of behavioral, medical, and surgical voice treatment options from the perspective of a variety of specialist practitioners with exceptional breadth and clarity. As suggested in the opening chapter, contemporary treatment of voice disorders draws on interdisciplinary expertise, and the book is true to that perspective. The team approach to voice treatment is realized through the contributions of laryngologists, speech-language pathologists, singing voice specialists, nurses, physiotherapists, acting voice trainers, and others. The reader will find discussion of various treatment procedures, including surgical, pharmacological, and behavioral. This text presents essential information that allows for the effective interaction of various specialties. For example, behavioral specialists can draw on the information that is given on surgery, trauma and injury, and medications. This book is at once a template for team-based treatment and a deep informational resource for treatment alternatives. Its scope and depth make it a book that the voice specialist will want to keep close at hand. New to this edition: New content on topics such as technology in the studio and pedagogy for children.Many topics have been expanded to highlight current practices, to include information published since the previous edition, and to present current management approaches.Chapters have been rewritten extensively to include the most current techniques and to reflect the latest beliefs and practices, as well as the most recent information from the evolving literature in this field.Chapter 16 on nutrition has been completely rewritten and includes important changes in criteria and strategy, reflecting developments in nutritional science over the past decade.New material on topics such as choral pedagogy for geriatric singers, laryngeal manipulation, and cosmetic procedures and their implications for voice professionals. Treatment of Voice Disorders, Second Edition is ideal for speech-language pathology students and clinicians and is suitable for classroom use as well as for reference. It is an essential volume for anyone concerned with voice disorders.

Download or read book Bad Bug Book written by Mark Walderhaug and published by Createspace Independent Publishing Platform. This book was released on 2014-01-14 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Bad Bug Book 2nd Edition, released in 2012, provides current information about the major known agents that cause foodborne illness.Each chapter in this book is about a pathogen—a bacterium, virus, or parasite—or a natural toxin that can contaminate food and cause illness. The book contains scientific and technical information about the major pathogens that cause these kinds of illnesses.A separate “consumer box” in each chapter provides non-technical information, in everyday language. The boxes describe plainly what can make you sick and, more important, how to prevent it.The information provided in this handbook is abbreviated and general in nature, and is intended for practical use. It is not intended to be a comprehensive scientific or clinical reference.The Bad Bug Book is published by the Center for Food Safety and Applied Nutrition (CFSAN) of the Food and Drug Administration (FDA), U.S. Department of Health and Human Services.

Download or read book Advancing Medicine with Food and Nutrients Second Edition written by Ingrid Kohlstadt and published by CRC Press. This book was released on 2012-12-10 with total page 913 pages. Available in PDF, EPUB and Kindle. Book excerpt: Food and nutrients are the original medicine and the shoulders on which modern medicine stands. But in recent decades, food and medicine have taken divergent paths and the natural healing properties of food have been diminished in the wake of modern technical progress. With contributions from highly regarded experts who work on the frontlines of disease management, the bestselling first edition of Advancing Medicine with Food and Nutrients, Food and Nutrients in Disease Management effectively brought food back into the clinical arena, helping physicians put food and nutrients back on the prescription pad. Board-certified in General Preventive Medicine, Ingrid Kohlstadt, MD, MPH has been elected a Fellow of the American College of Nutrition and a Fellow of the American College of Preventive Medicine. Guided by Dr. Kohlstadt, this authoritative reference equips clinicians with the information they need to fully utilize nutritional medicine in their practice. New in the Second Edition Toxic exposures such as molds, microbial infections, xenoestrogens, heavy metals, and inert nanoparticles Food safety issues: precautions for patients with preexisting medical conditions, adequate labeling of food allergens such as gluten, potential adverse effects of artificial sweeteners, consequences of applying ionizing radiation to food, food-borne mycotoxins, critical food restrictions following bariatric surgery, precautions for preparing food in the home Consumer advocacy issues on navigating claims of medical foods and dietary supplements Physical forces on nutritional needs, such as ultraviolet light initiating vitamin D synthesis, non-ionizing radiation’s effects on brain glucose metabolism and excess body fat’s effects on inflammation and hydration Preventive medicine and how to preserve resiliency at the individual and public health levels Written by doctors for doctors, Advancing Medicine with Food and Nutrients, Second Edition reunites food and medicine. Buttressed with new evidence, leading physicians on the frontlines of disease management apply the latest scientific advances to the clinical practice of medicine. Each chapter offers adjuncts to standard care, fewer side effects, improved risk reduction, or added quality of life. An article by Ingrid Kohlstadt on education and nutrition appeared in TIME Magazine online on November 12, 2014.

Download or read book Blackwell s Five Minute Veterinary Consult written by Larry P. Tilley and published by John Wiley & Sons. This book was released on 2021-04-06 with total page 1730 pages. Available in PDF, EPUB and Kindle. Book excerpt: Want access to this book online? The full book content is also available as part of VetConsult, an online subscription platform with a powerful search function. Find out more at www.wiley.com/learn/vetconsult and subscribe today at https://vetconsult.wiley.com/subscription. THE VERY LATEST INFORMATION ON DISEASES AND CLINICAL PROBLEMS IN DOGS AND CATS Blackwell’s Five-Minute Veterinary Consult: Canine and Feline, 7th Edition provides up-to-date information on feline and canine disease in the familiar, popular, and trusted 5-Minute Veterinary Consult format. This reference puts all the necessary information regarding common diseases and conditions in dogs and cats at the reader’s fingertips. Covering 845 specific disorders, Blackwell’s Five-Minute Veterinary Consult is the most comprehensive and timely reference on canine and feline medicine available today. It is carefully designed for fast and easy access to vital and accurate information. The companion website allows the reader to access more than 350 downloadable client education handouts, as well as images and video clips. The book makes it easy to find essential details on: 845 different diseases and conditions, from amebiasis to zinc toxicosis Diagnosis Common treatments and prognoses Blackwell’s Five-Minute Veterinary Consult: Canine and Feline is the leading quick-access reference for veterinary practitioners and students everywhere.

Download or read book Nuts and Seeds in Health and Disease Prevention written by Victor R Preedy and published by Academic Press. This book was released on 2020-04-24 with total page 598 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nuts and Seeds in Health and Disease Prevention, Second Edition investigates the benefits of nuts and seeds in health and disease prevention using an organizational style that will provide easy-access to information that supports identifying treatment options and the development of symptom-specific functional foods. This book examines seeds and nuts as agents that affect metabolism and other health-related conditions and explores the impact of compositional differences between various seeds and nuts, including differences based on country of origin and processing technique. Finally, the book includes methods for the analysis of seed and nut-related compounds. Written for nutrition researchers, nutritionists, food scientists, government regulators of food, and students of agriculture, oils and feeds, nutrition and life sciences, this book is sure to be a welcomed resource.

Download or read book Prescription for Herbal Healing 2nd Edition written by Phyllis A. Balch CNC and published by Penguin. This book was released on 2012-04-03 with total page 657 pages. Available in PDF, EPUB and Kindle. Book excerpt: The definitive source for choosing the optimal herbal therapy- thoroughly revised and updated. Millions of Americans are turning to herbal therapies to heal what ails them-either as an alternative or as a supplement to traditional medicine. From the most trusted name in natural healing, Phyllis A. Balch's new edition of Prescription for Herbal Healing provides the most current research and comprehensive facts in an easy-to-read A- to-Z format, including: Information on more than 200 herbs and herbal combination formulas, ranging from well-known herbs, such as ginseng and St. John's Wort, to less familiar remedies, such as khella and prickly ash Chinese and ayurvedic herbal combinations Discussion of more than 150 common disorders from acne to yeast infection, and suggested herbal treatment therapies

Download or read book Laurie Pippen s All Natural Antibacterial Agents written by Laurie Pippen and published by Eiram Publishing. This book was released on 2015-05-24 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: The classification antibacterial includes anything that destroys bacteria or inhibits the ability of bacteria to grow and reproduce. Herbals approach bacterial infection from two directions. They stimulate the immune system to produce more immune cells aiding your body’s ability to fight the infection and they act in direct opposition to bacteria by inhibiting their ability to grow and reproduce so they cannot survive. The first line of defense against bacterial infection is prevention. Disinfecting surfaces with known antibacterial cleaners, maintaining good health through diet, rest, and exercise, and minimizing exposure to infectious agents is far more effective than any treatment plan in the continued battle against bacteria. Regardless of the preventative care you take, there are always times where treating an infection will be necessary. Traditionally, bacterial infection is fought by blending herbals that support the body’s own natural defenses with those that act to inhibit and kill the bacteria. Using a combination that blends both actions helps to minimize the duration and severity of any infection. Many herbs and oils act as natural immunostimulant and antibacterial agents. Some of these natural products work as well as or even better than the products sold in your local pharmacy. Some of the items in your local pharmacy are even created based on the chemical constituents of plants you might have growing in your own yard. This guide contains antibacterial agents that act as both disinfectants for infected air and surfaces and disease fighting agents for the body. Both categories eliminate harmful bacteria. It is important that you read the traditional uses and side effects of each plant and discuss any alternative treatment with a qualified herbalist or physician prior to choosing a natural product.