Download or read book Engineered Nanopores for Bioanalytical Applications written by Joshua B. Edel and published by William Andrew. This book was released on 2013-03-19 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: Engineered Nanopores for Bioanalytical Applications is the first book to focus primarily on practical analytical applications of nanopore development. These nanoscale analytical techniques have exciting potential because they can be used in applications such as DNA sequencing, DNA fragment sizing, DNA/protein binding, and protein/protein binding. This book provides a solid professional reference on nanopores for readers in academia, industry and engineering and biomedical fields. In addition, the book describes the instrumentation, fabrication, and experimental methods necessary to carry out nanopore-based experiments for developing new devices. Includes application case studies for detection, identification and analysis of biomolecules and related functional nanomaterials Introduces the techniques of manufacturing solid state materials with functional nanopores Explains the use of nanopores in DNA sequencing and the wider range of applications from environmental monitoring to forensics
Download or read book Nanopores for Bioanalytical Applications written by Joshua Edel and published by Royal Society of Chemistry. This book was released on 2012-09-05 with total page 121 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioanalytical applications in nanopores are an exciting field of research which have seen rapid development over the last ten plus years. This book focuses uniquely on this research area providing an insight from the world leading experts in the area. Based on the proceedings of the 1st International Conference on Nanopores for Bioanalytical Applications (Lanzarote, 2012), it will provide a snapshot of this exciting field for the nanopores community. It describes the latest experimental and fabrication protocols necessary to carry out nanopore-based experiments and covers a wide variety of topics. These include: biological pores, solid state pores, hybrid structures, fundamental aspects, work on the underlying (bio)physics and applications in biosensing and DNA sequencing. The multidisciplinary approach to this topic makes the book suitable for readers in both academia and industry.
Download or read book Nanopores for Bioanalytical Applications written by Joshua Benno Edel and published by Royal Society of Chemistry. This book was released on 2012 with total page 121 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is based on the proceedings of the first International Conference on Nanopores for Bioanalytical Applications.
Download or read book Nanopores written by Samir M. Iqbal and published by Springer Science & Business Media. This book was released on 2011-07-12 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanopores are nanometer scale holes formed naturally by proteins or cells, and can be used for a variety of applications, including sequencing DNA and detecting anthrax. They can be integrated into artificially constructed encapsulated cells of silicon wafers while allowing small molecules like oxygen, glucose and insulin to pass, while keeping out large system molecules. "Nanopores: Sensing and Fundamental Biological Interactions" examines the emerging research directions surrounding nanopores such as genome sequencing and early disease detection using biomarker identification. Covering the applications of nanopores in genetics, proteomics, drug discovery, early disease detection and detection of emerging environmental threats, it is a must-have book for biomedicalengineers and research scientists.
Download or read book Nanopore Technology written by Monifa A.V. Fahie and published by Humana. This book was released on 2021-09-27 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed collection explores techniques involved in the main strategies of nanopore sensing, such as translocation, analyte trapping, and interactions with external binding sites. Opening with a section on nanopore design and nanopore production, the book continues with parts devoted to various biological nanopores, nanopore engineering, and their uses in single molecule sensing, computational methods to study intrinsic nanopore behavior, characterizing the specific translocation activity of a vesicle particle through a nanopore, as well as the use of the technique droplet interface bilayer (DIB) in nanopore and membrane biophysical studies. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Nanopore Technology: Methods and Protocols, with its focus on nanopore technology and biomolecule characterization, will hold the interest of the biophysicists, biochemists, bioengineers, and molecular biologists who are working toward further understanding this key field of research.
Download or read book Fundamentals and Applications of Solid State and Biological Nanopores written by Rukshan Tharanga Perera and published by . This book was released on 2016 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book New Approach in Fabrication of Solid State Nanopore for Bio Sensing Applications written by Wing Hei Harold Kwok and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Solid State Nanopores written by Kyle Briggs and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The work presented in this thesis is divided loosely into three main areas of interest: development of a novel method of solid-state nanopore fabrication; applications of this method to some of the open problems in the field; and analysis of nanopore data. The first of these occupies the majority of the research presented in this thesis, covering research dedicated to the development and characterization of a novel method of solid-state nanopore fabrication which achieves nanometer scale control over matter using simple and low cost circuitry. Termed controlled breakdown (CBD), this technique is in the process of revolutionizing the field of nanopore research, and in the few short years I have been part of its development it has seen adoption in nanopore labs across the globe, both academic and industrial. Due to the simple nature of CBD, this technique also enables novel applications of nanopores in device architectures that were inaccessible to the expensive and inflexible methods used previously. The second part of this thesis takes advantage of the unique opportunities presented by CBD to develop a device architecture comprising two nanopores in series. This nanodevice tackles one of the main problems standing between nanopores and the promise of cheap genomic analysis: control of the motion and conformation of the polymer both prior to and during translocation through the pore. Finally, because the field of nanopore research is still relatively young, very few tools are available which provide high-quality analysis of nanopore data. The last part of this thesis is dedicated to a thorough discussion of the complexities involved in analysing nanopore signals, as well as the development of several tools which directly address this knowledge gap.
Download or read book Development of New Biological Nanopores and Their Application for Biosensing and Disease Detection written by Shaoying Wang and published by . This book was released on 2016 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Characterization and Application of Membrane Spanning Synthetic and Biological Nanopores written by Vera Arnaut and published by . This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Confining Electrochemistry to Nanopores written by Yi-Tao Long and published by Royal Society of Chemistry. This book was released on 2020-10-26 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: The nanopore provides a highly electrochemically confined space within which single-molecule characteristics can be efficiently converted into measurable electrochemical signatures with high temporal and current resolution. Aimed at developing the concept of the electrochemical confined space in analysing single molecules, this book serves as a stepping-stone to many exciting discoveries in nanopore-based analysis of biological processes and chemical reactions in confined space. The field of nanopore sensors is growing rapidly, but there have been no new books on nanopore technology that provide an overview of the research on nanopore-based sensing until now. The book provides a good source of nanopore studies for researchers interested in and working in the general areas of electrochemistry and nanobiotechnology, especially on nanopore sensors.
Download or read book Biocompatible Graphene for Bioanalytical Applications written by Yuwei Hu and published by Springer. This book was released on 2014-12-04 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the latest advances in the use of graphene and bio-compatible-material-decorated graphene to detect various targets (e.g. DNA, RNA, amino acids, peptides, proteins, enzymes, antigens, glucose, DA, AA, UA, ATP, NADH, gas, ions, etc.). It focuses on the specific interaction of these substances with graphene (or modified graphene) and the efficient transduction of the target recognition event into detectable signals via various techniques. Particular emphasis is given to well-designed strategies for constructing graphene-based platforms and target determination. It also covers other bio-analytical applications including cellular imaging, drug delivery and bacteria inhibition, before turning to a discussion of future challenges and prospects of graphene in bio-analytical applications. This book is intended for researchers working in the fields of analytical chemistry, nanomaterials and biomedical engineering. Li Niu is a Professor at the State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences.
Download or read book Single Molecule and Single Cell Sequencing written by Yutaka Suzuki and published by Springer. This book was released on 2019-04-09 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents an overview of the recent technologies in single molecule and single cell sequencing. These sequencing technologies are revolutionizing the way of the genomic studies and the understanding of complex biological systems. The PacBio sequencer has enabled extremely long-read sequencing and the MinION sequencer has made the sequencing possible in developing countries. New developments and technologies are constantly emerging, which will further expand sequencing applications. In parallel, single cell sequencing technologies are rapidly becoming a popular platform. This volume presents not only an updated overview of these technologies, but also of the related developments in bioinformatics. Without powerful bioinformatics software, where rapid progress is taking place, these new technologies will not realize their full potential. All the contributors to this volume have been involved in the development of these technologies and software and have also made significant progress on their applications. This book is intended to be of interest to a wide audience ranging from genome researchers to basic molecular biologists and clinicians.
Download or read book Chemically Modified Nanopores and Nanochannels written by Mario Tagliazucchi and published by William Andrew. This book was released on 2016-08-29 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemically Modified Nanopores and Nanochannels is devoted to chemically modified nanopores and nanochannels, and covers the fundamentals of transport in chemically modified systems, an account of the different preparation and characterization techniques of chemically modified nanopores, their applications, and case studies. The book is designed for materials and biomaterials scientists, biomedical engineers, chemists, and chemical engineers who are interested in designing and utilizing processes to synthesize, modify, characterize, use, and model nanopores. The strong chemical focus of the book differentiates it from other books published on nanopores, which traditionally focus either on physics, biophysics, and nanofabrication (solid-state nanopores) or biophysics and biology (biological ion channels and pores). Explains how the chemical modification of nanopores and nanochannels can be used in filtration, membranes, and sensing Provides advanced coverage of novel synthetic applications Focuses on the latest developments in nanopore and nanochannel engineering Presents an account of the different preparation and characterization techniques of chemically modified nanopores, their applications, and case studies
Download or read book Nanotechnology for Sustainable Agriculture written by Vishnu D. Rajput and published by CRC Press. This book was released on 2023-09-08 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume explores the important and cutting-edge roles that nanotechnology can play in facilitating sustainable agriculture. It provides recent updates on nanobiotechnology in soil science, plant breeding, food science, agricultural tool design and utilization, as well as the impacts of such approaches on properties of soils and plants. The book looks at the use of nanotechnology for crop production and protection, in the creation and application of pesticides, to enhance soil fertility and soil health, as a mitigating factor of plant abiotic stress, and more. The volume explores emerging nanotechnological tools and techniques for crop improvement that include space-inspired speed breeding for crop improvement, nanoparticles as sensing materials, plant nanobionics, nanopore DNA sequencing, and more.
Download or read book Characterization of Nanoparticles written by Ing. V.-D. Hodoroaba and published by Elsevier. This book was released on 2019-10-05 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt: Characterization of Nanoparticles: Measurement Processes for Nanoparticles surveys this fast growing field, including established methods for the physical and chemical characterization of nanoparticles. The book focuses on sample preparation issues (including potential pitfalls), with measurement procedures described in detail. In addition, the book explores data reduction, including the quantitative evaluation of the final result and its uncertainty of measurement. The results of published inter-laboratory comparisons are referred to, along with the availability of reference materials necessary for instrument calibration and method validation. The application of these methods are illustrated with practical examples on what is routine and what remains a challenge. In addition, this book summarizes promising methods still under development and analyzes the need for complementary methods to enhance the quality of nanoparticle characterization with solutions already in operation. Helps readers decide which nanocharacterization method is best for each measurement problem, including limitations, advantages and disadvantages Shows which nanocharacterization methods are best for different classes of nanomaterial Demonstrates the practical use of a method based on selected case studies
Download or read book Electrostatics of Soft and Disordered Matter written by David S. Dean and published by CRC Press. This book was released on 2014-05-02 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recently, there has been a surge of activity to elucidate the behavior of highly charged soft matter and Coulomb fluids in general. Such systems are ubiquitous, especially in biological matter where the length scale and the strength of the interaction between highly charged biomolecules are governed by strong electrostatic effects. Several interesting limits have been discovered in the parameter space of highly charged many-particle Coulomb matter where analytical progress is possible and completely novel and unexpected results have been obtained. One of the challenges in highly charged matter is to correctly describe systems with finite coupling strength in the transition regime between weak and strong couplings. After studying the fluctuations of both, several theories have been developed that describe this experimentally highly relevant regime. At the same time, computer simulation algorithms and computing power have advanced to the level where all-ion simulations, including many-body and polarization effects, are possible; the new theories thus can be subjected to numerical confirmation. Another important question is the effect of the structural disorder on electrostatic interactions. It has recently been demonstrated, both theoretically and experimentally, that charge disorder can impose long-range interaction between charged or even uncharged surfaces. These interactions might become very significant in biological processes. Filling a void in the literature, this volume cross-pollinates different theoretical and simulation approaches with new experiments and ties together the low temperature, high coupling constant, and disorder parameters in a unified description of the electrostatic interactions, which largely determine the stability and conformations of most important biological macromolecules. With striking graphical illustrations, the book presents a unified view of the current advances in the field of Coulomb (bio)colloidal systems, building on previous literature that summarized the field over 20 years ago. Leading scientists in the field offer a detailed introduction to different modern methods in statistical physics of Coulomb systems. They detail various approaches to elucidate the behavior of strongly charged soft matter. They also provide experimental and theoretical descriptions of disorder effects in Coulomb systems, which have not been discussed in any other book.
