Download or read book Multidisciplinary Approaches to Cholinesterase Functions written by Avigdor Shafferman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Structure and Function of Cholinesterases and Related Proteins written by Bhupendra P. Doctor and published by Springer Science & Business Media. This book was released on 2013-11-27 with total page 627 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Sixth International Meeting on Cholinesterases and Related Proteins, Choli nesterases '98, was organized by Palmer Taylor and his associates at the University of California-San Diego and convened in La Jolla, California, USA, in March of 1998. This was the first conference of the series to be held in the United States, let alone on the Pa cific Rim. Nearly 200 delegates from twenty countries-from Asia, Australia, Europe, and North and South America-heard 75 oral presentations and viewed 90 posters on current research on cholinesterases and related proteins. The meeting framework was structured to include two days of plenary sessions, followed by two days of concurrent sessions and workshops in specific areas. Communication at the concurrent sessions was facilitated by the conference settings of the Martin Johnson House, on a scenic bluff overlooking the blue Pacific Ocean, and the San Diego Supercomputer Center, which enabled projection and rotation of protein structures in three dimensions for a large audience. This book is the compilation of the presentations at the Sixth International Meeting on Cholinesterases and Related Proteins into a volume that describes recent investigations on the structure, catalytic and non-catalytic functions of acetylcholinesterase (AChE), butyrylcholinesterase (BuChE), and related proteins, as well as studies on the molecular and cellular biology of these enzymes and the genes that encode them.
Download or read book Enzymes of the Cholinesterase Family written by A.S. Balasubramanian and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Fifth International Meeting on Cholinesterases convened in Madras, India, in September of 1994. The long and rich history and culture of India provided an excellent setting for the meeting. More than 120 delegates from Asia, Australia, Europe and North America heard 54 oral presentations and viewed 54 posters on current research on enzymes of the cholinesterase family. The aim of this book is to compile the presentations of the Fifth International Meeting on Cholinesterases into a volume that describes recent investigations on the structure and catalytic function of acetylcholinesterase (AChE), butyrylcholinesterase (BuChE) and related enzymes, as well as studies on the molecular and cellular biology of these enzymes and the genes which encode them. Cholinesterases enjoy a long and storied history in diverse areas. In basic biochemical research, AChE is one of the best studied, though yet enigmatic, of enzymes. The efficient catalytic function of this enzyme presents the biochemist with a fundamental challenge in understanding the relationship between structure and function. AChE and BuChE belong to a family of proteins, the alB hydrolase fold family, whose constituents evolutionarily diverged from a common ancestor. Proteins in this family have a wide range of physiological functions. In commerce, AChE is a prime target for agricultural insect control, and for the development of therapeutic agents for Alzheimer's disease.
Download or read book International Review of Cytology written by and published by Academic Press. This book was released on 2001-09-26 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: International Review of Cytology presents current advances and comprehensive reviews in cell biology--both plant and animal. Articles in this volume include the role and distribution of retinoic acid during CNS development, the role of receptor-associated protein (RAP) as a molecular chaperone for members of the LDL receptor family, the biology of cortical granules, acetylcholinesterase genes in the nematode caenorhabditis elegans, and reciprocal regulation of endothelin-1 and nitric oxide. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research.*The Role and Distribution of Retinoic Acid during CNS Development*The Roles of Receptor-Associated Protein (RAP) as a Molecular Chaperone for Members of the LDL Receptor Family*The Biology of Cortical Granules*Acetylcholinesterase Genes in the Namatode Caenorhabditis elegans*Receprocal Regulation of Endothelin-1 and Nitric Oxide: Relevance in the Physiology and Pathology of the Cardiovascular System
Download or read book Analogue based Drug Discovery written by IUPAC and published by John Wiley & Sons. This book was released on 2006-12-13 with total page 606 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first authoritative overview of past and current strategies for successful drug development by analog generation, this unique resource spans all important drug classes and all major therapeutic fields, including histamine antagonists, ACE inhibitors, beta blockers, opioids, quinolone antibiotics, steroids and anticancer platinum compounds. Of the 19 analog classes presented in detail, 9 are described by the scientists who discoverd them. The book includes a table of the most successful drug analogs as based on the IMS ranking and compares them in terms of chemical structure, mode of action and patentability.
Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1993 with total page 704 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.
Download or read book National Library of Medicine Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1993 with total page 1536 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Comparative Enzymology of Cholinesterases written by Serge N. Moralev and published by Internat'l University Line. This book was released on 2007 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Progress in Alzheimer s and Parkinson s Diseases written by Abraham Fisher and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 846 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book represents the fourth ina series of international conferences related to Alzheimer's (AD) and Parkinson's (PO) diseases. The first one took place in EHat, Israel in 1985; the second in Kyoto, Japan, in 1989; and the third in Chicago, IL, USA in 1993. This book incorporates the proceedings of the Fourth International Conference on Pro gress in Alzheimer's and Parkinson's Diseases, held in EHat, Israel, on May 18-23, 1997. This Conference was the 41st in the series of annual OHOLO Conferences sponsored by the Israel Institute for Biological Research (IIBR). It was also conducted under the aus pices of the Alzheimer's Association Ronald and Nancy Reagan Research Institute, USA. The Conference was attended by 550 participants from 28 countries, representing a broad spectrum of research interests; and included a well-balanced representation from aca demia, clinical institutions and pharmaceutical industry. The four-and-one-half day meeting served as an excellent medium for surveying the current preclinical and clinical develop ments in AD, PO, and other related disorders. The scientific program was divided into 24 oral sessions and daily poster sessions. The conference culminated in a round table discus sion. There were 122 talks and 161 posters. This book incorporates a combination of both.
Download or read book Recent Trends in the Acetylcholinesterase System written by Mahira Parveen and published by IOS Press. This book was released on 2005 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: The enzyme acetylcholinesterase (AChE) has drawn the attention of scientist as it has played a striking role in Alzheimer's disease, Cardiac diseases and other diseases. A good discussion and overview document on AChE enzyme and its various aspects was felt lacking since a long time in the field of enzyme biochemistry as well as enzyme biotechnology and this publication fills this gap. Before this publication there was no data available on AChE enzyme inhibition, its kinetics, its peripheral sites, their role in catalytic and noncholinergic function of enzyme, ACh receptors, AChE and BuChE genes etc. All these topics together form a good basis for researchers and post graduate students in this field of interest. This book is a collection of recent advanced reports and data on AChE enzyme.
Download or read book Exploring the Vertebrate Central Cholinergic Nervous System written by Alexander G. Karczmar and published by Springer Science & Business Media. This book was released on 2007-04-05 with total page 698 pages. Available in PDF, EPUB and Kindle. Book excerpt: Even if the “weapons of mass destruction” (WMD) and, among them, stocks of organoph- phorus (OP) agents (also referred to as war gases and nerve gases) were not found in Iraq following the US-Iraq war, the relative ease with which these substances can be made from harmless precursors and the low cost of their manufacture will continue to fascinate pow- hungry, ruthless dictators, as well as multinational and international terrorists, particularly as the close relationship between the OP agents and useful insecticides makes it easy to disguise the importation and purchase of small amounts of the precursors. Indeed, the use by Saddam Hussein of a nerve gas against the Kurds and his possible employment of the OP agents during his war with Iran, and the Sarin attack in the Tokyo underground by an extremist religious set magnetized the world with respect to the OP drugs. As these drugs exert their toxicity via their cholinergic action on the nervous, particularly central nervous, system, it is no wonder that the research in the cholinergic ? eld attracts, and merits, our intense attention. These considerations underlie the signi? cance of this book, as Alex Karczmar devotes an entire chapter of Exploring the Vertebrate Central Cholinergic Nervous System to anticholinest- ases (antiChEs), and as he is an acknowledged expert in the ? eld of cholinergic toxicity as well as a consultant to the Surgeon General of the U. S. Army.
Download or read book Handbook of Venoms and Toxins of Reptiles written by Stephen P. Mackessy and published by CRC Press. This book was released on 2016-04-19 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Venoms and Toxins of Reptiles offers "one-stop shopping" to all biologists, biochemists, toxicologists, physicians, clinicians, and epidemiologists, and informed laypersons interested in the biology of venomous reptiles, the biochemistry and molecular biology of venoms, and the effects and treatment of human envenomation. This book
Download or read book Animal Toxins written by Hervé Rochat and published by Springer Science & Business Media. This book was released on 2000 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural toxins form a major component of the molecular tools used increasingly frequently by the ever growing number of laboratories of various kinds. Evidence for this is provided not only by the increasing number of firms including such toxins in their catalogues but also by the large number of demands received by those who discover new toxins. Twenty chapters survey important aspects of toxin origin, their structure and molecular mechanism, and their cellular and pathogenic effects. In addition, the text provides comprehensive and specific methodology for the application of these toxins in the research laboratory. This begins with the description of the method of extraction, biochemical and pharmacological characterization, and assessment of purity, and continues with methods for chemical modification, e.g. labelling, and eventually describes applications in pharmacological studies in vivo and/or in vitro. The length of this book has been kept reasonable by concentrating on...
Download or read book Human Cholinesterases and Anticholinesterases written by Hermona Soreq and published by Academic Press. This book was released on 2012-12-02 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human Cholinesterases and Anticholinesterases summarizes the many fundamental concepts of human cholinesterases (ChEs) and their inhibitors. This book is divided into three chapters that represent human cholinesterase research studies from different points of view. Chapter 1 deals with the biochemical and biological background of human ChEs. This chapter also examines the molecular polymorphism, genomic origin, genetic variants, and biological roles of these enzymes. Chapter 2 provides the molecular characterization of human ChE genes and their multileveled regulation, with a special emphasis on butyrylcholinesterase. Chapter 3 discusses the scientific, ecological, and clinical implications of the studies presented in the previous chapters. Protein scientists, engineers, and researchers will find this work invaluable.
Download or read book Modelling of Biomolecular Structures and Mechanisms written by A. Pullman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gathering together a number of the best experts in the world, the 27th Jerusalem Symposium was devoted to the theme of the modelling of biomolecular structures and mechanisms. As a result of recent growth in both importance and audience, the papers contained in this volume present a thorough evaluation of the status of the present knowledge in this field. The main topics covered by this year's Symposium include nucleic acids and their interactions, proteins and their interaction, membranes and their interactions, enzymatic processes and the pharmacological and medical aspects of these subjects. Readers will benefit from the interdisciplinary approach which provides an extensive coverage of both theoretical and experimental advances.
Download or read book Sensing of Deadly Toxic Chemical Warfare Agents Nerve Agent Simulants and their Toxicological Aspects written by Sangita Das and published by Elsevier. This book was released on 2022-09-16 with total page 766 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sensing of Deadly Toxic Chemical Warfare Agents, Nerve Agent Simulants, and their Toxicological Aspects provides a general overview of the development and performance of different novel molecular frameworks as potent vehicles for sensing Chemical Weapons (CWs). The chapters are contributed by leading researchers in the areas of materials science, medical science, chemical science, and nanotechnology from industries, academics, government and private research institutions across the globe. It covers cover topics such as inorganic nanocomposites, hyperbranched polymers, and graphene heterojunctions for effective sensing of CW agents. This book is a highly valuable reference source for graduates, post-graduates, and research scholars primarily in the fields of materials science, medicinal chemistry, organic chemistry, and nanoscience and nanotechnology. In addition, almost all analytical techniques will be discussed, making this a first-rate reference for professors, students, and scientists in many industries. - Provides an efficient, reliable, and highly versatile approach for the synthesis of different molecular systems suitable for diversity-oriented strategies, structure-activity studies and molecular tailoring for the sensing of chemical warfare agents - Goes into depth on new binary organogels, discrete carbon nanomaterials (CNMs) and molecularly imprinted polymers (MIPs) and has endowed electrochemical chemosensors (ECCSs) with high selectivity and sensitivity towards the detection of chemical warfare agent - Highlights in detail the detection of CWs by composite optical waveguide sensors, and describes disposable biofilm biosensors for sensitive detection of biotoxicity in water with treatment of nerve agent poisoning
Download or read book Gestational Diabetes written by Miroslav Radenkovic and published by BoD – Books on Demand. This book was released on 2011-11-02 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gestational diabetes mellitus is defined as hyperglycemia with onset or first recognition during pregnancy. The incidence of gestational diabetes is still increasing and this pathological condition has strong association with adverse pregnancy outcomes. Since gestational diabetes can have long-term pathological consequences for both mother and the child, it is important that it is promptly recognized and adequately managed. Treatment of gestational diabetes is aimed to maintain euglycemia and it should involve regular glucose monitoring, dietary modifications, life style changes, appropriate physical activity, and when necessary, pharmacotherapy. Adequate glycemic control throughout the pregnancy can notably reduce the occurrence of specific adverse perinatal and maternal outcomes. In a long-term prospect, in order to prevent development of diabetes later in life, as well to avoid associated complications, an adequate education on lifestyle modifications should start in pregnancy and continue postpartum.
