Download or read book Monte Carlo Based Treatment Planning for Modulated Electron Radiotherapy Using a Photon Multileaf Collimator written by Dominik Henzen and published by . This book was released on 2014 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Application of Monte Carlo Simulations to the Development of Energy and Intensity modulated Electron Beam Radiation Therapy written by Michael C. Lee and published by . This book was released on 2002 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Monte Carlo Treatment Planning with Modulated Electron Radiotherapy written by Andrew William Alexander and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Within the field of medical physics, Monte Carlo radiation transport simulations are considered to be the most accurate method for the determination of dose distributions in patients. The McGill Monte Carlo treatment planning system (MMCTP), provides a flexible software environment to integrate Monte Carlo simulations with current and new treatment modalities. A developing treatment modality called energy and intensity modulated electron radiotherapy (MERT) is a promising modality, which has the fundamental capabilities to enhance the dosimetry of superficial targets. An objective of this work is to advance the research and development of MERT with the end goal of clinical use. To this end, we present the MMCTP system with an integrated toolkit for MERT planning and delivery of MERT fields. Delivery is achieved using an automated "few leaf electron collimator" (FLEC) and a controller. Aside from the MERT planning toolkit, the MMCTP system required numerous...
Download or read book Monte Carlo Characterisation of Electron Beams Transported Through a Photon Multi leaf Collimator for Use in Modulated Electron Radiation Therapy written by Omer A. Ali and published by . This book was released on 2009 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Penthorum Its Chromosomes written by J. T. Baldwin (Jr.) and published by . This book was released on 1951 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Mixed Electron photon Radiation Therapy Treatment Planning and Delivery written by Marc-André Renaud and published by . This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: "In linac-based radiation therapy, the bulk of recent innovations have involved delivering photon radiation over an ever-growing range of beam delivery angles around the patient, rather than incorporating more particle types into the treatment planning process.Mixed beam radiation therapy (MBRT) is the concept of creating and delivering treatment plans involving multiple modalities, such as multiple photon and electron energies. Combined electron-photon treatment plans can reduce the dose to normal tissue compared to photon-only treatments for patients with a superficial tumour due to the limited range of electrons in matter. However, MBRT has yet to be implemented widely in a clinical environment due to primitive optimisation models and the cumbersome collimation devices typically used in electron delivery. In this work, the components necessary for the creation and validation of mixed electron-photon radiation therapy plans delivered with a photon multi-leaf collimator (pMLC) as the sole collimation device were developed, characterised and validated.As neither MBRT nor pMLC-collimated electron deliveries are part of routine clinical practice, it was necessary to first create an academic treatment planning system (TPS) capable of visualising patient images and dose distributions and coordinating the creation of the beamlet dose distributions necessary for treatment plan optimisation. A collapsed cone convolution superposition dose calculation engine was implemented to generate photon beamlet dose distributions. Electron beamlet dose distributions were created using the DOSXYZnrc Monte Carlo dose calculation engine coupled to a validated electron beam model. The TPS was programmed to interface with the two dose calculation engines in order to facilitate the beamlet generation process.Secondly, a column generation-based (CG) direct aperture optimisation model for MBRT planning was derived and subsequently implemented. Using beamlets created for each modality, the algorithm iteratively creates a treatment plan by producing candidate electron and photon apertures at each iteration, and selecting the apertures most likely to improve the cost function. A study of the algorithm showed that it could successfully produce MBRT plans with a better cost function compared to photon-only and electron-only plans. Next, the robustness of MBRT dose distributions to patient positioning uncertainties was studied. The CG-based MBRT model was extended to explicitly ensure that clinical target volume (CTV) coverage is preserved under a series of setup error scenarios. The study showed that traditional PTV-based optimisation is inadequate for MBRT planning, whereas robust CTV-based optimisation was able to produce plans which maintained adequate coverage under all setup error scenarios considered.Finally, two MBRT plans were delivered on a solid water slab phantom and an acrylic cylinder, respectively. The accuracy of the deliveries was assessed using film dosimetry and by measuring the dose on the central axis of the acrylic cylinder using an ionisation chamber. The solid water slab film agreed with the simulated dose distribution with a 96.4 % pass rate for a 2 %/2 mm gamma criteria. On the cylindrical acrylic phantom, the measured dose for the combined MBRT delivery agreed within 0.2 %. Broken down by modality, the agreement between measured and simulated dose in the ionisation chamber varied between -0.8 % and +2.7 %. We conclude that our beam models can accurately simulate MBRT dose distributions, however, further investigation is needed to confirm that the deliveries are sufficiently robust to positioning uncertainties.This body of work demonstrates that a mixed electron-photon treatment planning algorithm based on the column generation method can produce realistic, deliverable and verifiable treatment plans which offer superior normal tissue sparing compared to current state-of-the-art single-modality photon or electron plans." --
Download or read book A Monte Carlo Model of Quality Assurance of Intensity Modulated Radiotherapy written by Randi Fogg Aaronson and published by . This book was released on 2003 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Monte Carlo Dose Calculations for Clinical Electron and Intensity Modulated Photon Beams in Radiotherapy written by Ajay Kapur and published by . This book was released on 1999 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Use of Computers in Radiation Therapy written by Wolfgang Schlegel and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 630 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computers have had and will continue to have a tremendous impact on professional activity in almost all areas. This applies to radiological medicine and in particular to radiation therapy. This book compiles the most recent developments and results of the application of computers and computer science as presented at the XIIIth International Conference on the Use of Computers in Radiation Therapy in Heidelberg, Germany. The text of both oral presentations and posters is included. The book is intended for computer sientists, medical physicists, engineers and physicians in the field of radiation therapy and provides a comprehensive survey of the entire field.
Download or read book Monte Carlo Treatment Planning for Molecular Targeted Radiotherapy Within the MINERVA System written by D. Nigg and published by . This book was released on 2004 with total page 28 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this project is to extend accurate and patient-specific treatment planning to new treatment modalities, such as molecular targeted radiation therapy, incorporating previously crafted and proven Monte Carlo and deterministic computation methods. A flexible software environment is being created that allows planning radiation treatment for these new modalities and combining different forms of radiation treatment with consideration of biological effects. The system uses common input interfaces, medical image sets for definition of patient geometry, and dose reporting protocols. Previously, the Idaho National Engineering and Environmental Laboratory (INEEL), Montana State University (MSU), and Lawrence Livermore National Laboratory (LLNL) had accrued experience in the development and application of Monte Carlo-based, three-dimensional, computational dosimetry and treatment planning tools for radiotherapy in several specialized areas. In particular, INEEL and MSU have developed computational dosimetry systems for neutron radiotherapy and neutron capture therapy, while LLNL has developed the PEREGRINE computational system for external beam photon-electron therapy. Building on that experience, the INEEL and MSU are developing the MINERVA (Modality Inclusive Environment for Radiotherapeutic Variable Analysis) software system as a general framework for computational dosimetry and treatment planning for a variety of emerging forms of radiotherapy. In collaboration with this development, LLNL has extended its PEREGRINE code to accommodate internal sources for molecular targeted radiotherapy (MTR), and has interfaced it with the plug-in architecture of MINERVA. Results from the extended PEREGRINE code have been compared to published data from other codes, and found to be in general agreement (EGS4 - 2%, MCNP - 10%)(Descalle et al. 2003). The code is currently being benchmarked against experimental data. The interpatient variability of the drug pharmacokinetics in MTR can only be properly accounted for by image-based, patient-specific treatment planning as has been common in external beam radiation therapy for many years. MINERVA offers 3D Monte Carlo based MTR treatment planning as its first integrated operational capability. The new MINERVA system will ultimately incorporate capabilities for a comprehensive list of radiation therapies. In progress are modules for external beam photon-electron therapy and Boron Neutron Capture Therapy (BNCT). Brachytherapy and Protontherapy are planned. Through the open Application Programming Interface (API) other groups can add their own modules and share them with the community.
Download or read book Intensity modulated Radiation Therapy written by American Association of Physicists in Medicine. Summer School and published by Medical Physics Publishing Corporation. This book was released on 2003 with total page 912 pages. Available in PDF, EPUB and Kindle. Book excerpt: IMRT represents a new paradigm in the radiation therapy process that requires knowledge of multimodality imaging, setup uncertainties and internal organ motion, tumor control probabilities, normal tissue complication probabilities, three-dimensional dose calculation and optimization and dynamic beam delivery of non-uniform beam intensities. Written by contributors who are among the foremost in the field, this book presents a snapshot of the current IMRT planning and delivery technology. It discusses issues that confront safe implementation of IMRT and encourages reflection on its future. The result is a "handbook" that will aid both experienced radiation oncology physicists and newcomers to the field in understanding the nuances of IMRT and its safe implementation in the clinics. The level of presentation is designed for practicing medical physicists who are not specialists in IMRT. Some issues such as imaging and target delineation, quality assurance and its frequency, and achievable accuracy are discussed in multiple chapters and from differing points of view, reflecting the diversity of opinions in this rapidly evolving field.
Download or read book The VCM Code System Monte Carlo Simulation of Electron and Photon Transport for Application in Radiation Treatment Planning written by I. Kawrakow and published by . This book was released on 2000 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book A Photon Phase Space Source Model Incorporating Efficient Sampling Algorithms for Clinical Radiotherapy Treatment Planning Using the Monte Carlo Method written by Indrin Chetty and published by . This book was released on 1999 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Adaptive Intensity Modulated Radiotherapy for Advanced Prostate Cancer written by Erica Marie Ludlum and published by . This book was released on 2008 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Modern Technology of Radiation Oncology written by Jake Van Dyk and published by Medical Physics Publishing Corporation. This book was released on 1999 with total page 1106 pages. Available in PDF, EPUB and Kindle. Book excerpt: Details technology associated with radiation oncology, emphasizing design of all equipment allied with radiation treatment. Describes procedures required to implement equipment in clinical service, covering needs assessment, purchase, acceptance, and commissioning, and explains quality assurance issues. Also addresses less common and evolving technologies. For medical physicists and radiation oncologists, as well as radiation therapists, dosimetrists, and engineering technologists. Includes bandw medical images and photos of equipment. Paper edition (unseen), $145.95. Annotation copyrighted by Book News, Inc., Portland, OR
Download or read book Monte Carlo Techniques in Radiation Therapy written by Frank Verhaegen and published by CRC Press. This book was released on 2021-11-29 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: About ten years after the first edition comes this second edition of Monte Carlo Techniques in Radiation Therapy: Introduction, Source Modelling, and Patient Dose Calculations, thoroughly updated and extended with the latest topics, edited by Frank Verhaegen and Joao Seco. This book aims to provide a brief introduction to the history and basics of Monte Carlo simulation, but again has a strong focus on applications in radiotherapy. Since the first edition, Monte Carlo simulation has found many new applications, which are included in detail. The applications sections in this book cover the following: Modelling transport of photons, electrons, protons, and ions Modelling radiation sources for external beam radiotherapy Modelling radiation sources for brachytherapy Design of radiation sources Modelling dynamic beam delivery Patient dose calculations in external beam radiotherapy Patient dose calculations in brachytherapy Use of artificial intelligence in Monte Carlo simulations This book is intended for both students and professionals, both novice and experienced, in medical radiotherapy physics. It combines overviews of development, methods, and references to facilitate Monte Carlo studies.
Download or read book Monte Carlo Calculations and Measurement of Photon Beams Shaped by Multileaf Collimators in Radiation Therapy written by Nikolas L. Marinos and published by . This book was released on 1999 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
