Download or read book Molecular Neuropharmacology ie written by NESTLER and published by . This book was released on 2020-10-21 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular Neuropharmacology A Foundation for Clinical Neuroscience Fourth Edition written by Eric J. Nestler and published by McGraw-Hill Education / Medical. This book was released on 2020-07-24 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. This popular primer provides a solid understanding of the nervous system, neurologic disorders, and treatments with drugs and other substances Nestler, Hyman, and Malenka’s Molecular Neuropharmacology, Fourth Edition covers everything you need to know about molecular neuroscience. This meticulously detailed guide provides a deep dive into the pathophysiology of neurologic and psychiatric disorders by describing neuropharmacological fundamentals of the nervous system. Packed with tables, diagrams, and figures making the intricacies of neurochemistry easy to understand, it builds a solid understanding of major disease mechanisms by reviewing the effects of drug actions (organized by drug category), and it explains the neuropharmacology of specific neural and psychiatric disorders. Concise overviews of the effects of drugs and neurologically active substances appear before the descriptions of the minute details that lead to these effects—a format designed to boost understanding and knowledge retention of critical concepts.
Download or read book Molecular Neuropharmacology written by Eric J. Nestler and published by McGraw Hill Professional. This book was released on 2008-10-12 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt: Market: Pharmacy and medical students; neuroscientists; neurologists; pharmacologists Updated edition has an attractive full-color design with more illustrations Includes numerous Fact Boxes to help reinforce learning
Download or read book Molecular Neuropharmacology written by Eric J. Nestler and published by . This book was released on 2008 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular Neuropharmacology A Foundation for Clinical Neuroscience Third Edition written by Eric J. Nestler and published by McGraw Hill Professional. This book was released on 2015-03-22 with total page 543 pages. Available in PDF, EPUB and Kindle. Book excerpt: GAIN A COMPLETE UNDERSTANDING OF NERVOUS SYSTEM FUNCTION AND ITS RELATIONSHIP TO HUMAN NEUROLOGIC DISORDERS Molecular Neuropharmacology first reviews the fundamental biochemistry of the functioning nervous system and then describes how nerve cells communicate with one another through numerous types of neurotransmitters involving amino acids, monoamines, neuropeptides, and neurotrophic factors, among several others. The neuropharmacology and neural circuits that underlie complex behaviors as well as major neural disorders are also discussed as are the drugs used to treat those conditions. In the final section, the authors use the concepts presented in the first two sections to explainhow irregularities in the biochemistry of neuronal interactions can lead to a wide array of clinical manifestations. FEATURES NEW chapter on neuroinflammation All chemical structure illustrations have been redrawn and improved Fully updated to reflect the latest breakthroughs and new drugs The most well-written and easily understood work on the subject More than 300 full-color illustrations!
Download or read book Molecular Neuropharmacology written by Arne Schousboe and published by Springer Science & Business Media. This book was released on 2003-12-22 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: A powerful collection of readily reproducible cutting-edge techniques for characterizing the ligand or substrate binding of neurotransmitter receptors and transporters. The procedures cover interdisciplinary interactions for monoamine transporters, amino acid transporters, ionotropic receptors, metabotropic glutamate receptors, GABA receptors, and other G protein-coupled receptors. By illuminating how neurons in the central nervous communicate with other, these techniques can lead to the development of novel therapeutic strategies for neurological diseases.
Download or read book Caffeine for the Sustainment of Mental Task Performance written by Institute of Medicine and published by National Academies Press. This book was released on 2002-01-07 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report from the Committee on Military Nutrition Research reviews the history of caffeine usage, the metabolism of caffeine, and its physiological effects. The effects of caffeine on physical performance, cognitive function and alertness, and alleviation of sleep deprivation impairments are discussed in light of recent scientific literature. The impact of caffeine consumption on various aspects of health, including cardiovascular disease, reproduction, bone mineral density, and fluid homeostasis are reviewed. The behavioral effects of caffeine are also discussed, including the effect of caffeine on reaction to stress, withdrawal effects, and detrimental effects of high intakes. The amounts of caffeine found to enhance vigilance and reaction time consistently are reviewed and recommendations are made with respect to amounts of caffeine appropriate for maintaining alertness of military personnel during field operations. Recommendations are also provided on the need for appropriate labeling of caffeine-containing supplements, and education of military personnel on the use of these supplements. A brief review of some alternatives to caffeine is also provided.
Download or read book Molecular Basis of Neuropharmacology A Foundation for Clinical Neuroscience written by Eric J. Nestler and published by McGraw Hill Professional. This book was released on 2001-03-28 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: * The most up-to-date and comprehensive coverage of the relationship of brain function and neuroactive chemicals * Authors are world-known leaders in the field * Molecular Neuropharmacology is the hot topic in medicine
Download or read book Phytocannabinoids written by A. Douglas Kinghorn and published by Springer. This book was released on 2017-01-24 with total page 137 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book presents the current state of the art on phytocannnabinoid chemistry and pharmacology and will be of much use to those wishing to understand the current landscape of the exciting and intriguing phytocannabinoid science. The focus is on natural product cannabinoids which have been demonstrated to act at specific receptor targets in the CNS.
Download or read book Introduction to Neuropsychopharmacology written by Leslie Iversen and published by Oxford University Press. This book was released on 2009 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: The text ranges from drugs that affect the mood and behavior to hypnotics, narcotics, anticonvulsants, and analgesics, as well as a variety of drugs that affect the autonomic nervous system and psychoactive drugs used for non-medical reasons - nicotine, alcohol, opiates, psychostimulants and cannabis."--BOOK JACKET.
Download or read book Molecular Neuropharmacology written by Eric Jonathan Nestler and published by McGraw-Hill Medical Publishing. This book was released on 2001 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt: * The most up-to-date and comprehensive coverage of the relationship of brain function and neuroactive chemicals * Authors are world-known leaders in the field * Molecular Neuropharmacology is the hot topic in medicine.
Download or read book Principles of Pharmacology written by David E. Golan and published by Lippincott Williams & Wilkins. This book was released on 2011-12-15 with total page 978 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its third edition, Principles of Pharmacology presents content in a conceptual framework that maximizes understanding and retention and minimizes rote memorization. It takes students "beyond the disease" and deep into physiologic, biochemical, and pathophysiologic systems where drugs activate or inhibit these systems by interacting with molecular and cellular targets. This unique approach ensures understanding of the mechanisms of drug actions on the body, and ultimately, in treating the human patient. Ideal for introductory pharmacology courses that emphasize critical thinking, molecular understanding, systems-based integration, and clinical preparation, the text: Features chapter-opening clinical cases and questions to establish a context for the discussion and the answers that follow Presents signature drug summary tables, updated and organized by mechanism of action, with information on clinical applications, adverse effects, contraindications, and therapeutic considerations Incorporates NEW full-color illustrations throughout, suiting the needs of visual learners and more effectively presenting concepts covered in the narrative Integrates timely content, including recently approved drugs as well as current research on drug mechanisms of action Delivers course and review material appropriate for students through a uniquely collaborative authorship consisting of medical students, residents, and faculty
Download or read book Committee on Military Nutrition Research written by Institute of Medicine and published by National Academies Press. This book was released on 1999-08-04 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: The activities of the Food and Nutrition Board's Committee on Military Nutrition Research (CMNR, the committee) have been supported since 1994 by grant DAMD17-94-J-4046 from the U.S. Army Medical Research and Materiel Command (USAMRMC). This report fulfills the final reporting requirement of the grant, and presents a summary of activities for the grant period from December 1, 1994 through May 31, 1999. During this grant period, the CMNR has met from three to six times each year in response to issues that are brought to the committee through the Military Nutrition and Biochemistry Division of the U.S. Army Research Institute of Environmental Medicine at Natick, Massachusetts, and the Military Operational Medicine Program of USAMRMC at Fort Detrick, Maryland. The CMNR has submitted five workshop reports (plus two preliminary reports), including one that is a joint project with the Subcommittee on Body Composition, Nutrition, and Health of Military Women; three letter reports, and one brief report, all with recommendations, to the Commander, U.S. Army Medical Research and Materiel Command, since September 1995 and has a brief report currently in preparation. These reports are summarized in the following activity report with synopses of additional topics for which reports were deferred pending completion of military research in progress. This activity report includes as appendixes the conclusions and recommendations from the nine reports and has been prepared in a fashion to allow rapid access to committee recommendations on the topics covered over the time period.
Download or read book Improving and Accelerating Therapeutic Development for Nervous System Disorders written by Institute of Medicine and published by National Academies Press. This book was released on 2014-02-06 with total page 107 pages. Available in PDF, EPUB and Kindle. Book excerpt: Improving and Accelerating Therapeutic Development for Nervous System Disorders is the summary of a workshop convened by the IOM Forum on Neuroscience and Nervous System Disorders to examine opportunities to accelerate early phases of drug development for nervous system drug discovery. Workshop participants discussed challenges in neuroscience research for enabling faster entry of potential treatments into first-in-human trials, explored how new and emerging tools and technologies may improve the efficiency of research, and considered mechanisms to facilitate a more effective and efficient development pipeline. There are several challenges to the current drug development pipeline for nervous system disorders. The fundamental etiology and pathophysiology of many nervous system disorders are unknown and the brain is inaccessible to study, making it difficult to develop accurate models. Patient heterogeneity is high, disease pathology can occur years to decades before becoming clinically apparent, and diagnostic and treatment biomarkers are lacking. In addition, the lack of validated targets, limitations related to the predictive validity of animal models - the extent to which the model predicts clinical efficacy - and regulatory barriers can also impede translation and drug development for nervous system disorders. Improving and Accelerating Therapeutic Development for Nervous System Disorders identifies avenues for moving directly from cellular models to human trials, minimizing the need for animal models to test efficacy, and discusses the potential benefits and risks of such an approach. This report is a timely discussion of opportunities to improve early drug development with a focus toward preclinical trials.
Download or read book Introduction to Neuropharmacology written by Philip B. Bradley and published by Butterworth-Heinemann. This book was released on 2014-04-24 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction to Neuropharmacology presents the action of drugs as it relates to nervous system. It discusses the purposes into which drugs are use (e.g. as contraceptives and anti-riot agents). It addresses the differences between physiology and pharmacology. Some of the topics covered in the book are the factors affecting responses to drugs; properties of drugs; the kinetics of drug-receptor interactions; dose-response relationship; the principles of synaptic transmission; criteria for synaptic transmitters; somatic motor system; drugs affecting neuromuscular transmission; and drugs which act post-synaptically. The venoms and toxins that affect neuromuscular transmission are covered. The subdivisions of the autonomic nervous system are discussed. The text describes the autonomic ganglion stimulants. A study of the drugs mimicking parasympathetic stimulation is presented. A chapter is devoted to the drugs with antagonist actions on adrenoceptors. Another section focuses on the clinical uses of local anaesthetic drugs and the neurotransmitters in the central nervous system. The book can provide useful information to dentists, doctors, pharmacists, neurologists, students, and researchers.
Download or read book The Biochemical Basis of Neuropharmacology written by Jack R. Cooper and published by Oxford University Press, USA. This book was released on 2003 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aside from the usual updating of material, the major change in this edition is an extensive rewriting of the chapter on memory and learning to emphasize that genes that are involved in behavior are not immutable but their expression can be modified by transcription factors. Thus, with respect to learning, that old question about which is more important, nature or nuture, genetics or environment, should be answered with the question, which leg is more important for walking, the left or the right?
Download or read book Pain Management and the Opioid Epidemic written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-09-28 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.
