Download or read book Molecular Nanomachines of the Presynaptic Terminal written by Silvio O. Rizzoli and published by Frontiers Media SA. This book was released on 2016-10-18 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synaptic transmission is the basis of neuronal communication and is thus the most important element in brain functions, ranging from sensory input to information processing. Changes in synaptic transmission can result in the formation or dissolution of memories, and can equally lead to neurological and psychiatric disorders. The proteins composing the synapse, and their respective functions, are getting increasingly known. One aspect that has become evident in the last years is that most synaptic functions are performed not by single proteins, but by highly organized multi-protein machineries, which interact dynamically to provide responses optimally suited to the needs of the neuronal network. To decipher synaptic and neuronal function, it is essential to understand the organisational, morphological and functional aspects of the molecular nanomachines that operate at the synapse. We discuss these aspects in 11 different chapters, focusing on the structure and function of the active zone, on the functional anatomy of the synaptic vesicle, and on some of the best known soluble protein complexes from the synapse, including those involved in endocytosis and vesicle recycling.
Download or read book Molecular Nanomachines of the Presynaptic Terminal Volume II written by Silvio O. Rizzoli and published by Frontiers Media SA. This book was released on 2022-06-30 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular Nanomachines of the Presynaptic Terminal written by and published by . This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synaptic transmission is the basis of neuronal communication and is thus the most important element in brain functions, ranging from sensory input to information processing. Changes in synaptic transmission can result in the formation or dissolution of memories, and can equally lead to neurological and psychiatric disorders. The proteins composing the synapse, and their respective functions, are getting increasingly known. One aspect that has become evident in the last years is that most synaptic functions are performed not by single proteins, but by highly organized multi-protein machineries, which interact dynamically to provide responses optimally suited to the needs of the neuronal network. To decipher synaptic and neuronal function, it is essential to understand the organisational, morphological and functional aspects of the molecular nanomachines that operate at the synapse. We discuss these aspects in 11 different chapters, focusing on the structure and function of the active zone, on the functional anatomy of the synaptic vesicle, and on some of the best known soluble protein complexes from the synapse, including those involved in endocytosis and vesicle recycling.
Download or read book The Road from Nanomedicine to Precision Medicine written by Shaker. A Mousa and published by CRC Press. This book was released on 2020-01-06 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: The enormous advances in nanomedicine and precision medicine in the past two decades necessitated this comprehensive reference, which can be relied upon by researchers, clinicians, pharmaceutical scientists, regulators, policymakers, and lawyers alike. This standalone, full-color resource broadly surveys innovative technologies and advances pertaining to nanomedicine and precision medicine. In addition, it addresses often-neglected yet crucial areas such as translational medicine, intellectual property law, ethics, policy, FDA regulatory issues, nano-nomenclature, and artificial nano-machines—all accomplished in a user-friendly, broad yet interconnected format. The book is essential reading for the novice and the expert alike in diverse fields such as medicine, law, pharmacy, genomics, biomedical sciences, ethics, and regulatory science. The book’s multidisciplinary approach will attract a global audience and serve as a valuable reference resource for industry, academia, and government.
Download or read book Cellular Nanomachines written by Bhanu P. Jena and published by Springer Nature. This book was released on 2020-04-29 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, the major paradigm-shifting discoveries made in the past century on key cellular nanomachines are described in great detail: their complex yet precise and elegant design and function, as well as the diseases linked to their dysfunction and the therapeutic approaches to overcome them. The major focus of this book is the “porosome” nanomachine, the universal secretory portal in cells. This is an ideal book for students, researchers, and professionals in the fields of nanoscience and nanotechnology.
Download or read book Cellular and Molecular Neurophysiology written by Constance Hammond and published by Elsevier. This book was released on 2024-05-30 with total page 602 pages. Available in PDF, EPUB and Kindle. Book excerpt: Unveiling the latest research in neurophysiology, Cellular and Molecular Neurophysiology, Fifth Edition continues to stand as the only resource in the field. This book remains the standard for those who seek to explore the intricate molecular and cellular physiology of neurons and synapses. Notably, this new edition delves even deeper into the molecular properties and functions of excitable cells, offering unparalleled insights. In this edition, there are two groundbreaking chapters. The first reviews metabotropic receptors for olfactory transduction, while the second presents cutting-edge techniques for neuroscience research. Hypothesis-driven rather than a dry presentation of facts, the content firmly based on numerous experiments performed by top experts in the field, teaches students how to build and conduct intelligent research experiments. This book promotes a true understanding of nerve cell function and will be a useful resource for practicing neurophysiologists, neurobiologists, neurologists, and students in a graduate-level course on the topic alike. - Authoritative foundational coverage of basic cellular and molecular neurophysiology - Includes new chapters on metabotropic olfactory receptors for sensory transduction and experimental techniques used by neurophysiologists
Download or read book Introduction to Nanoscience and Nanotechnology written by Gabor L. Hornyak and published by CRC Press. This book was released on 2008-12-22 with total page 1791 pages. Available in PDF, EPUB and Kindle. Book excerpt: The maturation of nanotechnology has revealed it to be a unique and distinct discipline rather than a specialization within a larger field. Its textbook cannot afford to be a chemistry, physics, or engineering text focused on nano. It must be an integrated, multidisciplinary, and specifically nano textbook. The archetype of the modern nano textbook
Download or read book Journal of Biomedical Nanotechnology written by and published by . This book was released on 2005 with total page 668 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Nanotechnology for the Regeneration of Hard and Soft Tissues written by Thomas J. Webster and published by World Scientific. This book was released on 2007 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology is an emerging and exciting area in the field of implants. Numerous promising developments have been elucidated regarding the use of nanotechnology to regenerate tissues. This important book highlights the potential of nanophase materials to improve hard and soft tissue applications. In all cases, increased tissue regeneration has been observed for bone, cartilage, vascular, bladder, and central/peripheral nervous system tissues.
Download or read book Protein Trafficking in Neurons written by Andrew J. Bean and published by Elsevier. This book was released on 2006-10-27 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: The efficient delivery of cellular constituents to their proper location is of fundamental importance for all cells and is of particular interest to neuroscientists, because of the unique functions and complex architecture of neurons. Protein Trafficking in Neurons examines mechanisms of protein trafficking and the role of trafficking in neuronal functioning from development to plasticity to disease. The book is divided into seven sections that review mechanisms of protein transport, the role of protein trafficking in synapse formation, exo- and endocytosis, transport of receptors, trafficking of ion channels and transporters, comparison of trafficking mechanisms in neuronal vs. non-neuronal cell types, and the relationship between trafficking and neuronal diseases such as Alzheimer's, Huntington's and Prion Diseases. - Provides a comprehensive examination of membrane/protein movement in neuronal function - Sections on synapse development, synaptic transmission, and the role of trafficking in neurological disease - Includes a focus on Molecular Mechanisms - Illustrated with color summary pictures - The only book examining protein trafficking and its functional implications, written by leaders in the field
Download or read book Lectures in Neuroscience written by Rafael Yuste and published by Columbia University Press. This book was released on 2023-08-15 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: The human brain is perhaps the most intricate and fascinating object in the known universe. Through a mysterious process, the activity of billions of neurons within a few pounds of matter generates the unfathomable complexity of the mind. This book is a conversational and accessible introduction to the brain. Beginning from basic elements of neuroscience, the acclaimed scientist Rafael Yuste guides readers through increasingly sophisticated topics, developing a unified framework for how the brain functions. He describes how the brain is organized and how it develops, how neurons operate and form neural circuits, and how these circuits function as neural networks to generate behavior and mental states. Yuste challenges the traditional view that the brain is an input-output machine that reacts reflexively to sensory stimuli. Instead, he argues, the purpose of the brain is to make a predictive model of the world in order to anticipate the future and choose successful courses of action. He gives readers insight into the workings of sensory and motor systems and the neurobiological basis of our perceptions, thoughts, emotions, memories, and consciousness. Peppered with anecdotes and illustrated with elegant drawings and diagrams, this succinct and cohesive book is accessible to readers without previous background in the subject. It is written for anyone seeking to grasp the core principles of neuroscience or looking for a fresh and clear perspective on how the brain works.
Download or read book Ultimate Computing written by S.R. Hameroff and published by Elsevier. This book was released on 2014-04-11 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: The possibility of direct interfacing between biological and technological information devices could result in a merger of mind and machine - Ultimate Computing. This book, a thorough consideration of this idea, involves a number of disciplines, including biochemistry, cognitive science, computer science, engineering, mathematics, microbiology, molecular biology, pharmacology, philosophy, physics, physiology, and psychology.
Download or read book BIOTECHNOLOGY Volume XI written by Horst W. Doelle and published by EOLSS Publications. This book was released on 2009-11-16 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Encyclopedia of Biotechnology is a component of the global Encyclopedia of Life Support Systems (EOLSS), which is an integrated compendium of twenty one Encyclopedias. Biotechnology draws on the pure biological sciences (genetics, animal cell culture, molecular biology, microbiology, biochemistry, embryology, cell biology) and in many instances is also dependent on knowledge and methods from outside the sphere of biology (chemical engineering, bioprocess engineering, information technology, biorobotics). This 15-volume set contains several chapters, each of size 5000-30000 words, with perspectives, applications and extensive illustrations. It carries state-of-the-art knowledge in the field and is aimed, by virtue of the several applications, at the following five major target audiences: University and College Students, Educators, Professional Practitioners, Research Personnel and Policy Analysts, Managers, and Decision Makers and NGOs.
Download or read book The Synapse written by Virginia M. Pickel and published by Elsevier. This book was released on 2013-11-16 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Synapse summarizes recent advances in cellular and molecular mechanisms of synaptic transmission and provides new insights into neuronal plasticity and the cellular basis of neurological diseases. - Part 1 provides an in-depth look at structural differences and distribution of various pre- and post-synaptic proteins found at glutamatergic synapses. - Part 2 is dedicated to dendritic spines and their associated perisynaptic glia, which together constitute the tripartite synapse. The spines are portrayed as major sites for calcium sequestration and local protein synthesis. - Part 3 highlights the important regional and cellular differences between glutamatergic transmission and that of neurotransmitters such as dopamine and acetylcholine that are commonly found in axon terminals without synaptic membrane specializations. - Part 4 provides an overview of the synapse from the time of formation to degeneration under the powerful influence of aging or hormonal decline that leads to severe deficits in cognitive function. Each chapter is illustrated with drawings and images derived from calcium imaging, electron microscopic immunolabeling, or electrophysiology. This book is a valuable reference for neuroscientists and clinical neurologists in both research and clinical settings. - A comprehensive reference focused on the structure and function of the synapse - Covers the links between the synapse and neural plasticity and the cellular basis of neurologic disease - Detailed coverage of dendritic spines and associated perisynaptic glia—the tripartite synapse - Includes in-depth coverage of synapse degeneration due to aging or hormonal decline related to severe cognitive impairment
Download or read book Neuromuscular Junctions in Drosophila written by and published by Academic Press. This book was released on 1999-04-29 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuromuscular Junctions in Drosophila gathers the main contributions that research using the fruit fly Drosophila melanogaster has made in the area of synapse development, synapse physiology, and excitability of muscles and nerve cells. The chapters in this book represent a synthesis of major advances in our understanding of neuronal development and synaptic physiology, which have been obtained using the above approach.This book is directed to the general neuroscience audience: researchers, instructors, graduate students, and advanced undergraduates who are interested in the mechanisms of synapse development and physiology. However, the book will also be a valuable resource for those that use the fruit fly as a model system in their laboratories.Key Features* Synthesizes the genetic approaches used to study synaptic development and function at the neuromuscular junction, using flies as a model system* Covers major recent advances in muscle development, pathfinding, synapse maturation and plasticity, exo- and endocytosis, and ion channel function* Written in clear language that is easily understandable to readers not already familiar with fruit fly research* Includes numerous diagrams and extensive reference lists
Download or read book The Neuron written by Irwin B. Levitan and published by Oxford University Press, USA. This book was released on 2002 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intended for use by advanced undergraduate, graduate and medical students, this book presents a study of the unique biochemical and physiological properties of neurons, emphasising the molecular mechanisms that generate and regulate their activity.
Download or read book Index Medicus written by and published by . This book was released on 2001 with total page 1932 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
