Download or read book Molecular Epidemiology of Chronic Diseases written by Chris Wild and published by John Wiley & Sons. This book was released on 2011-09-09 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: "I think this is an excellent book–I recommend it to anyone involved in molecular epidemiology... The 26 chapters are written by topic specialists, in an explanatory, east to read style." –BTS Newsletter, Summer 2009 "This text provides an accessible and useful handbook for the epidemiologist who wants to survey the field, to become better informed, to look at recent developments and get some background on these or simply to appreciate further the relatively rapid changes in informatic and analytical technologies which increasingly will serve and underpin future epidemiological studies. One of the strengths in this book is the extensive array of practical illustrative examples, and it would also in my opinion have useful potential as a teaching text." –American Journal of Human Biology, March 2009 With the sequencing of the human genome and the mapping of millions of single nucleotide polymorphisms, epidemiology has moved into the molecular domain. Scientists can now use molecular markers to track disease-associated genes in populations, enabling them to study complex chronic diseases that might result from the weak interactions of many genes with the environment. Use of these laboratory generated biomarker data and an understanding of disease mechanisms are increasingly important in elucidating disease aetiology. Molecular Epidemiology of Disease crosses the disciplinary boundaries between laboratory scientists, epidemiologists, clinical researchers and biostatisticians and is accessible to all these relevant research communities in focusing on practical issues of application, rather than reviews of current areas of research. Covers categories of biomarkers of exposure, susceptibility and disease Includes chapters on novel technologies: genomics, transcriptomics, proteomics and metabonomics, which are increasingly finding application in population studies Emphasizes new statistical and bioinformatics approaches necessitated by the large data sets generated using these new methodologies Demonstrates the potential applications of laboratory techniques in tackling epidemiological problems while considering their limitations, including the sources of uncertainty and inaccuracy Discusses issues such as reliability (compared to traditional epidemiological methods) and the timing of exposure Explores practical elements of conducting population studies, including biological repositories and ethics Molecular Epidemiology of Disease provides an easy-to-use, clearly presented handbook that allows epidemiologists to understand the specifics of research involving biomarkers, and laboratory scientists to understand the main issues of epidemiological study design and analysis. It also provides a useful tool for courses on molecular epidemiology, using many examples from population studies to illustrate key concepts and principles.
Download or read book Molecular Epidemiology written by Paul A. Schulte and published by Academic Press. This book was released on 2012-12-02 with total page 609 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will serve as a primer for both laboratory and field scientists who are shaping the emerging field of molecular epidemiology. Molecular epidemiology utilizes the same paradigm as traditional epidemiology but uses biological markers to identify exposure, disease or susceptibility. Schulte and Perera present the epidemiologic methods pertinent to biological markers. The book is also designed to enumerate the considerations necessary for valid field research and provide a resource on the salient and subtle features of biological indicators.
Download or read book Molecular Tools and Infectious Disease Epidemiology written by Betsy Foxman and published by Academic Press. This book was released on 2010-12-28 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Tools and Infectious Disease Epidemiology examines the opportunities and methodologic challenges in the application of modern molecular genetic and biologic techniques to infectious disease epidemiology. The application of these techniques dramatically improves the measurement of disease and putative risk factors, increasing our ability to detect and track outbreaks, identify risk factors and detect new infectious agents. However, integration of these techniques into epidemiologic studies also poses new challenges in the design, conduct, and analysis. This book presents the key points of consideration when integrating molecular biology and epidemiology; discusses how using molecular tools in epidemiologic research affects program design and conduct; considers the ethical concerns that arise in molecular epidemiologic studies; and provides a context for understanding and interpreting scientific literature as a foundation for subsequent practical experience in the laboratory and in the field. The book is recommended for graduate and advanced undergraduate students studying infectious disease epidemiology and molecular epidemiology; and for the epidemiologist wishing to integrate molecular techniques into his or her studies. - Presents the key points of consideration when integrating molecular biology and epidemiology - Discusses how using molecular tools in epidemiologic research affects program design and conduct - Considers the ethical concerns that arise in molecular epidemiologic studies - Provides a context for understanding and interpreting scientific literature as a foundation for subsequent practical experience in the laboratory and in the field
Download or read book The Infectious Etiology of Chronic Diseases written by Institute of Medicine and published by National Academies Press. This book was released on 2004-06-16 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, a number of chronic diseases have been linked, in some cases definitively, to an infectious etiology: peptic ulcer disease with Helicobacter pylori, cervical cancer with several human papillomaviruses, Lyme arthritis and neuroborreliosis with Borrelia burgdorferi, AIDS with the human immunodeficiency virus, liver cancer and cirrhosis with hepatitis B and C viruses, to name a few. The proven and suspected roles of microbes does not stop with physical ailments; infections are increasingly being examined as associated causes of or possible contributors to a variety of serious, chronic neuropsychiatric disorders and to developmental problems, especially in children. The Infectious Etiology of Chronic Diseases: Defining the Relationship, Enhancing the Research, and Mitigating the Effects, summarizes a two-day workshop held by the Institute of Medicine's Forum on Microbial Threats to address this rapidly evolving field. Participants explored factors driving infectious etiologies of chronic diseases of prominence, identified difficulties in linking infectious agents with chronic outcomes, and discussed broad-based strategies and research programs to advance the field.
Download or read book A Life Course Approach to Chronic Disease Epidemiology written by Diana Kuh and published by Oxford University Press. This book was released on 2004-04 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: From reviews of the previous edition:'We still have much to learn if disease patterns are to be explained by taking a life course approach... this book provides strong arguments for this approach... the book is a highly qualified starting point for the debate... it will remain a useful summary of pioneer research of huge potential importance for public health.' -Epidemiology'This is not just another epidemiology textbook. It is essential reading for anyone with an active mind who is interested in public health.' -Journal of Public Health Medicine'A truly exciting and extremely informative endeavour for anyone interested in the determinants of human health and disease. This discussion is at the core of current public health issues.' -European Journal of Public Health'The conclusion is of major importance to public health policy. It reinforces the need for a life course strategy, with attention being paid to the mother, baby, child adolescent, and elderly person.' -BMJ'Provokes thought about the origins of chronic diseases, suggests new approaches to identifying particular susceptible individuals and encourages the identification of optimal points in the life course for possible preventive interventions.' -Chronic Diseases in CanadaThe first edition in 1997 of A life course approach to chronic disease epidemiology became a classic text for epidemiological and public health researchers interested in the childhood origins of adult chronic disease. Since then the new field of life course epidemiology has expanded rapidly, attracting the interest not only of academics across the health and social sciences but also policy makers, funding bodies, and the general public. Its purpose is to study how biological and social factors during gestation, childhood, adolescence and earlier adult life independently, cumulatively and interactively influence later life health and disease.Contributors to this fully revised second edition capture the excitement of the developing field and assess the latest evidence regarding sources of risk to health across the life course and across generations. The original chapters on life course influences on cardiovascular disease, diabetes, blood pressure, respiratory disease and cancer have been updated and extended. New chapters on life course influences on obesity, biological ageing and neuropsychiatric disorders have been added. Life course explanations for disease trends and for socioeconomic differentials in disease risk are given more attention in this new edition, reflecting recent developments in the field. The section on policy implications has been expanded, assessing the role of interventions to improve childhood social circumstances, as well as interventions to improve early growth. Emerging new research themes and the theoretical and methodological challenges facing life course epidemiology are highlighted.Readership: Epidemiologists, public health researchers, public health policy makers for developed and developing countries, sociologists and biologists, psychiatrists and social and chronic disease epidemiologists
Download or read book Molecular Epidemiology of Infectious Diseases written by Lee W. Riley and published by . This book was released on 2004 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designed as both a textbook and a reference, this book outlines the principles, methods, and application of this new discipline of public health. Techniques used in the field of molecular biology have been recognized as critical tools in solving infectious disease problems. This introductory volume, distinguishing molecular epidemiology from taxonomy and phylogeny, will familiarize epidemiologists with molecular biology and molecular biologists with epidemiology, and presents vocabulary and concepts of both fields to infectious disease clinicians.
Download or read book Concepts of Epidemiology written by Raj S. Bhopal and published by Oxford University Press. This book was released on 2016 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: First edition published in 2002. Second edition published in 2008.
Download or read book Oxford Textbook of Medical Mycology written by Christopher C. Kibbler and published by Oxford University Press. This book was released on 2017-12-14 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Oxford Textbook of Medical Mycology is a comprehensive reference text which brings together the science and medicine of human fungal disease. Written by a leading group of international authors to bring a global expertise, it is divided into sections that deal with the principles of mycology, the organisms, a systems based approach to management, fungal disease in specific patient groups, diagnosis, and treatment. The detailed clinical chapters take account of recent international guidelines on the management of fungal disease. With chapters covering recent developments in taxonomy, fungal genetics and other 'omics', epidemiology, pathogenesis, and immunology, this textbook is well suited to aid both scientists and clinicians. The extensive illustrations, tables, and in-depth coverage of topics, including discussion of the non-infective aspects of allergic and toxin mediated fungal disease, are designed to aid the understanding of mechanisms and pathology, and extend the usual approach to fungal disease. This textbook is essential reading for microbiologists, research scientists, infectious diseases clinicians, respiratory physicians, and those managing immunocompromised patients. Part of the Oxford Textbook in Infectious Disease and Microbiology series, it is also a useful companion text for students and trainees looking to supplement mycology courses and microbiology training.
Download or read book Guiding Principles for Developing Dietary Reference Intakes Based on Chronic Disease written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-12-21 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since 1938 and 1941, nutrient intake recommendations have been issued to the public in Canada and the United States, respectively. Currently defined as the Dietary Reference Intakes (DRIs), these values are a set of standards established by consensus committees under the National Academies of Sciences, Engineering, and Medicine and used for planning and assessing diets of apparently healthy individuals and groups. In 2015, a multidisciplinary working group sponsored by the Canadian and U.S. government DRI steering committees convened to identify key scientific challenges encountered in the use of chronic disease endpoints to establish DRI values. Their report, Options for Basing Dietary Reference Intakes (DRIs) on Chronic Disease: Report from a Joint US-/Canadian-Sponsored Working Group, outlined and proposed ways to address conceptual and methodological challenges related to the work of future DRI Committees. This report assesses the options presented in the previous report and determines guiding principles for including chronic disease endpoints for food substances that will be used by future National Academies committees in establishing DRIs.
Download or read book Oxford Textbook of Global Public Health written by Roger Detels and published by Oxford University Press. This book was released on 2017 with total page 1717 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sixth edition of the hugely successful, internationally recognised textbook on global public health and epidemiology, with 3 volumes comprehensively covering the scope, methods, and practice of the discipline
Download or read book Health Without Borders written by Paolo Vineis and published by Springer. This book was released on 2017-06-02 with total page 115 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses globalization and its impact on human health. The population of the world grew from 1 billion in 1800 to 7 billion in 2012, and over the past 50 years the mean temperature has risen faster than ever before. Both factors continue to rise, as well as health inequalities. Our environment is changing rapidly, with tremendous consequences for our health. These changes produce complex and constantly varying interactions between the biosphere, economy, climate and human health, forcing us to approach future global health trends from a new perspective. Preventive actions to improve health, especially in low-income countries, are essential if our future is going to be a sustainable one. After a period of undeniable improvement in the health of the world’s population, this improvement is likely to slow down and we will experience– at least locally – crises of the same magnitude as have been observed in financial markets since 2009. There is instability in health systems, which will worsen if preventive and buffering mechanisms do not take on a central role. We cannot exclude the possibility that the allied forces of poverty, social inequalities, climate change, industrial food and lack of governance will lead to a deterioration in the health of large sectors of the population. In low-income countries, while many of the traditional causes of death (infectious diseases) are still highly prevalent, other threats typical of affluent societies (obesity, diabetes, cardiovascular diseases) are increasing. Africa is not only affected by malaria, TB and HIV, but also by skyrocketing rates of cancer. The book argues that the current situation requires effective and coordinated multinational interventions guided by the principle of health as a common good. An entirely competition-driven economy cannot – by its very nature – address global challenges that require full international cooperation. A communal global leadership is called for. Paolo Vineis is Chair of Environmental Epidemiology at Imperial College. His current research activities focus on examining biomarkers of disease risk as well as studying the effects of climate change on non-communicable diseases. “From morality to molecules, environment to equity, climate change to cancer, and politics to pathology, this is a wonderful tour of global health – consistently presented in a clear, readable format. Really, an important contribution.” Professor Sir Michael Marmot Director, Institute of Health Equity University College London Author of “The Health Gap” “This book is a salutary and soundly argued reminder that the ‘common good’ is not simply what remains after individuals and groups have appropriated the majority of societal resources: it is in fact the foundation on which any society rests and without which it collapses.” Rodolfo Saracci, International Agency for Research on Cancer, Lyon, France
Download or read book Principles of Psychiatric Genetics written by John I. Nurnberger and published by Cambridge University Press. This book was released on 2012-09-13 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive, up-to-date resource providing information about genetic influences on disorders of behavior.
Download or read book Chronic Inflammation written by Sashwati Roy and published by CRC Press. This book was released on 2012-09-17 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although acute inflammation is a healthy physiological response indicative of wound healing, chronic inflammation has been directly implicated in a wide range of degenerative human health disorders encompassing almost all present day non-communicable diseases including autoimmune diseases, obesity, diabetes and atherosclerosis. Chronic Inflammation
Download or read book Chronic Pain Epidemiology written by Peter Croft and published by Oxford University Press, USA. This book was released on 2010-09-30 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an invaluable framework and basis for thinking about chronic pain and the potential for its prevention in public health terms.
Download or read book Clinical Epidemiology written by Patrick S. Parfrey and published by Humana. This book was released on 2016-10-08 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on improving the diagnosis, prognosis, and management of human disease, this book takes on the issues of research design, measurement, and evaluation which are critical to clinical epidemiology. This second edition of Clinical Epidemiology: Practice and Methods opens with how best to frame a clinical research question, the ethics associated with doing a research project in humans, and the definition of various biases that occur in clinical research. From there, it continues by examining issues of design, measurement, and analysis associated with various research designs, including determination of risk in longitudinal studies, assessment of therapy in randomized controlled clinical trials, and evaluation of diagnostic tests, and then delves into the more specialized area of clinical genetic research, before concluding with basic methods used in evidence-based decision making including critical appraisal, aggregation of multiple studies using meta-analysis, health technology assessment, clinical practice guidelines, development of health policy, translational research, how to utilize administrative databases, and knowledge translation. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detail and practical advice to ensure real world success. Comprehensive and authoritative, Clinical Epidemiology: Practice and Methods, Second Edition is intended to educate researchers on how to undertake clinical research and should be helpful not only to medical practitioners but also to basic scientists who want to extend their work to humans, to allied health professionals interested in scientific evaluation, and to trainees in clinical epidemiology.
Download or read book Microbial Forensics written by Bruce Budowle and published by Academic Press. This book was released on 2010-10-27 with total page 753 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbial Forensics is a rapidly evolving scientific discipline. In the last decade, and particularly due to the anthrax letter attacks in the United States, microbial forensics has become more formalized and has played an increasingly greater role in crime investigations. This has brought renewed interest, development and application of new technologies, and new rules of forensic and policy engagement. It has many applications ranging from biodefense, criminal investigations, providing intelligence information, making society more secure, and helping protect precious resources, particularly human life. A combination of diverse areas is investigated, including the major disciplines of biology, microbiology, medicine, chemistry, physics, statistics, population genetics, and computer science. Microbial Forensics, Second Edition is fully revised and updated and serves as a complete reference of the discipline. It describes the advances, as well as the challenges and opportunities ahead, and will be integral in applying science to help solve future biocrimes. - A collection of microbiology, virology, toxicology and mycology as it relates to forensics, in one reference - New and expanded content to include statistical analysis of forensic data and legal admissibility and the standards of evidence, to name a few - Includes research information and application of that research to crime scene analysis, which will allow practitioners to understand and apply the knowledge to their practice with ease
