Download or read book The Development Of Dictyostelium Discoideum written by William Loomis and published by Elsevier. This book was released on 2012-12-02 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Development of Dictyostelium discoideum consists of 11 chapters representing the 11 major aspects at which continuous progress are made in the study of Dictyostelium discoideum. This book begins with the discovery, classification, ecology, and development of Dictyostelium discoideum. It then outlines the advances in genetic manipulation and mutant isolation of the organism. Much of the advances in cell biology have been related to a better understanding of the composition and function of the cell membrane. Hence, analyses of Dictyostelium plasma membranes are collated. This reference material also describes the role of chemoattractants in organizing cell movements and the intracellular events triggered by occupancy of chemoreceptors. It also explains the understanding of the macromolecular components of the chemosensory system of Dictyostelium discoideum. It further discusses the cell motility, cell adhesion, morphogenetic signaling, cytodifferentiation, and gene expression in the species. Finally, the phenomenon of cell-type specification and regulation in this organism is addressed. This book will be valuable for those already familiar with the general outlines of Dictyostelium biology.
Download or read book The Dictyostelids written by Kenneth Bryan Raper and published by Princeton University Press. This book was released on 2014-07-14 with total page 467 pages. Available in PDF, EPUB and Kindle. Book excerpt: Kenneth Raper tells how dictyostelids are isolated, cultivated, and conserved in the laboratory; how myxamoebae aggregate to form multicellular pseudoplasmodia; how fructifications arise by transformation of amoeboid cells into stalk cells and spores; and how similar cells can, under certain conditions, enter a sexual phase. For each known dictyostelid Professor Raper includes a complete description and photographic illustrations; one new species is described. Originally published in 1984. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.
Download or read book Handbook of the Protists written by John M. Archibald and published by Springer. This book was released on 2017-08-16 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Published in a modern, user-friendly format this fully revised and updated edition of The Handbook of Protoctista (1990) is the resource for those interested in the biology, diversity and evolution of eukaryotic microorganisms and their descendants, exclusive of animals, plants and fungi. With chapters written by leading researchers in the field, the content reflects the present state of knowledge of the cell and genome biology, evolutionary relationships and ecological/medical/economic importance each major group of protists, organized according to current protist systematics as informed by molecular phylogenetics and genomics.
Download or read book Dictyostelium discoideum Protocols written by Ludwig Eichinger and published by Springer Science & Business Media. This book was released on 2008-02-02 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dictyostelium discoideum is a simple but fascinating eukaryotic microorg- ism, whose natural habitat is deciduous forest soil and decaying leaves, where the amoebae feed on bacteria and grow as independent single cells. Exhaustion of the bacterial food source triggers a developmental program, in which up to 100,000 cells aggregate by chemotaxis towards cAMP. Morphogenesis and cell different- tion then culminate in the production of spores enabling the organism to survive unfavorable conditions. Dictyostelium offers unique advantages for studying f- damental cellular processes with the aid of powerful molecular genetic, bioche- cal, and cell biological tools. These processes include signal transduction, chemotaxis, cell motility, cytokinesis, phagocytosis, and aspects of development such as cell sorting, pattern formation and cell type differentiation. Recently, D- tyostelium was also described as a suitable host for pathogenic bacteria in which one can conveniently study the process of infection. In addition, Dictyostelium has many of the experimental conveniences of Saccharomyces cerevisiae and is pr- ably the best experimentally manipulatable protozoan, providing insight into this diverse group of organisms, which includes some of the most dangerous human parasites. The recent completion of the Dictyostelium genome sequencing project strengthens the position of D. discoideum as a model organism. The completed genome sequence and other valuable community resources constitute the source for basic biological and biomedical research and for genome-wide analyses.
Download or read book The Molecular Biology of Arrestins written by and published by Academic Press. This book was released on 2013-06-10 with total page 545 pages. Available in PDF, EPUB and Kindle. Book excerpt: This special volume of Progress in Molecular Biology and Translational Science focuses on the molecular biology of arrestins, with contributions from leaders in the field. Arrestins have emerged as central players in the regulation of many facets of G protein-coupled receptor signaling. This volume covers a variety of topics with reviews written by experts in the field. - Contributions from leading authorities - Informs and updates on all the latest developments in the field
Download or read book Fluorescent and Luminescent Probes for Biological Activity written by W. T. Mason and published by Elsevier. This book was released on 1999-04-16 with total page 697 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of fluorescent and luminescent probes to measure biological function has increased dramatically since publication of the First Edition due to their improved speed, safety, and power of analytical approach. This eagerly awaited Second Edition, also edited by Bill Mason, contains 19 new chapters and over two thirds new material, and is a must for all life scientists using optical probes.The contents include discussion of new optical methodologies for detection of proteins, DNA and other molecules, as well as probes for ions, receptors, cellular components, and gene expression. Emerging and advanced technologies for probe detection such as confocal laser scanning microscopy are also covered. This book will be essential for those embarking on work in the field or using new methods to enhance their research.TOPICS COVERED:* Single and multiphoton confocal microscopy* Applications of green fluorescent protein and chemiluminescent reporters to gene expression studies* Applications of new optical probes for imaging proteins in gels * Probes and detection technologies for imaging membrane potential in live cells* Use of optical probes to detect microorganisms* Raman and confocal raman microspectroscopy* Fluorescence lifetime imaging microscopy* Digital CCD cameras and their application in biological microscopy
Download or read book Glycoproteins II written by J. Montreuil and published by Elsevier Science. This book was released on 1997-12-22 with total page 651 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part II of this excellent work covers proteoglycans and mucins and deals with many more examples of glycoprotein function. It also covers glycoproteins from four more species (slime mold, snails, fish, batracians). The content of the volume is very comprehensive in that most contributors are focussed on discussing, in depth, the wealth of most recent advances in their field, referring to previous reviews of older work for background information. This method effectively produces a very wide subject coverage in a smaller number of chapters/volumes. The volume is an important information source for all glycobiologist researchers (senior investigators, post-doctoral fellows and graduate students), and as a good, comprehensive, reference text for scientists working in the life sciences.
Download or read book Physical Biology of the Cell written by Rob Phillips and published by Garland Science. This book was released on 2012-10-29 with total page 1089 pages. Available in PDF, EPUB and Kindle. Book excerpt: Physical Biology of the Cell is a textbook for a first course in physical biology or biophysics for undergraduate or graduate students. It maps the huge and complex landscape of cell and molecular biology from the distinct perspective of physical biology. As a key organizing principle, the proximity of topics is based on the physical concepts that
Download or read book Microtubules in vivo written by and published by Academic Press. This book was released on 2010-09-24 with total page 549 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microtubules: in vivo includes chapters by experts around the world on many aspects of microtubule imaging in living and fixed cells; assays to study microtubule function in a wide array of model organisms and cultured cells; high resolution approaches to study of the cytoskeleton. The authors share their years of experience, outlining potential pitfalls and critical factors to consider in experimental design, experimental implementation and data interpretation. - Includes chapters by experts around the world on many aspects of microtubule imaging in living and fixed cells; assays to study microtubule function in a wide array of model organisms and cultured cells; high resolution approaches to study of the cytoskeleton - The authors share their years of experience, outlining potential pitfalls and critical factors to consider in experimental design, experimental implementation and data interpretation
Download or read book The Social Biology of Microbial Communities written by Institute of Medicine and published by National Academies Press. This book was released on 2013-01-10 with total page 633 pages. Available in PDF, EPUB and Kindle. Book excerpt: Beginning with the germ theory of disease in the 19th century and extending through most of the 20th century, microbes were believed to live their lives as solitary, unicellular, disease-causing organisms . This perception stemmed from the focus of most investigators on organisms that could be grown in the laboratory as cellular monocultures, often dispersed in liquid, and under ambient conditions of temperature, lighting, and humidity. Most such inquiries were designed to identify microbial pathogens by satisfying Koch's postulates.3 This pathogen-centric approach to the study of microorganisms produced a metaphorical "war" against these microbial invaders waged with antibiotic therapies, while simultaneously obscuring the dynamic relationships that exist among and between host organisms and their associated microorganisms-only a tiny fraction of which act as pathogens. Despite their obvious importance, very little is actually known about the processes and factors that influence the assembly, function, and stability of microbial communities. Gaining this knowledge will require a seismic shift away from the study of individual microbes in isolation to inquiries into the nature of diverse and often complex microbial communities, the forces that shape them, and their relationships with other communities and organisms, including their multicellular hosts. On March 6 and 7, 2012, the Institute of Medicine's (IOM's) Forum on Microbial Threats hosted a public workshop to explore the emerging science of the "social biology" of microbial communities. Workshop presentations and discussions embraced a wide spectrum of topics, experimental systems, and theoretical perspectives representative of the current, multifaceted exploration of the microbial frontier. Participants discussed ecological, evolutionary, and genetic factors contributing to the assembly, function, and stability of microbial communities; how microbial communities adapt and respond to environmental stimuli; theoretical and experimental approaches to advance this nascent field; and potential applications of knowledge gained from the study of microbial communities for the improvement of human, animal, plant, and ecosystem health and toward a deeper understanding of microbial diversity and evolution. The Social Biology of Microbial Communities: Workshop Summary further explains the happenings of the workshop.
Download or read book International Review of Cytology written by and published by Academic Press. This book was released on 1997-12-10 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: International Review of Cytology presents current advances and comprehensive reviews in cell biology-both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. - The Cellular Basis of Tumor Progression - Molecules Involved in Mammalian Serm-Egg Interaction - Coordinated Nuclear and Chloroplast Gene Expression in Plants - Signaling in Unicellular Eukaryotes - Metabolic Detoxificiation of So2 in plants
Download or read book Progress in Molecular and Subcellular Biology written by Philippe Jeanteur and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological functions are almost exclusively attributed to macromolecules, i.e. nucleic acids, proteins and polysaccharides. To gain their complete functional activities these biomolecules have to associate with the nuclear matrix, the cytoskeleton and the cell/plasma membranes. It is the aim of this series to discuss actual aspects in the field of structure-associated genetic and epigenetic functional processes. This series of survey reviews fills the gap in structure-associated information flow, and is a vital reference work for scientists in molecular and cell biology.
Download or read book Dictyostelids written by Maria Romeralo and published by Springer Science & Business Media. This book was released on 2013-07-16 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since their discovery in 1869, the dictyostelids have attracted the attention of scientists in a wide variety of fields. This interest has stemmed from their peculiar lifestyle and developmental properties, which were shaped by the evolutionary forces that generated multicellularity during eukaryotic evolution. More recently, the dictyostelids have gained attention due to the striking similarities found at the genomic, cellular and biochemical levels with human cells, which has propelled the species Dictyostelium discoideum to become a model system for biology and medicine in many laboratories. This book covers the latest advances in our knowledge of these extraordinary organisms with topics spanning from their evolutionary history, ecology and diversity to the recent discoveries regarding their cellular and molecular biology.
Download or read book Cell to Cell Signalling written by A. Goldbeter and published by Academic Press. This book was released on 2014-06-28 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell to Cell Signalling: From Experiments to Theoretical Models is a collection of papers from a NATO Workshop conducted in Belgium in September 1988. The book discusses nerve cells and neural networks involved in signal transfers. The works of Hodgkin and Huxley presents a prototypic combination between experimental and theoretical approaches. The book discusses the coupling process found between secretory cells that modify their behavior. The text also analyzes morphogenesis and development, and then emphasizes the pattern formation found in Drosophila and in the amphibian embryo. The text also cite examples of immunological modeling that is related to the dynamics of immune networks based on idiotypic regulation. One paper analyzes the immune dynamism of HIV infection. The text notes that hormone signaling can be attributed as responsible for intercellular communication. Another paper examines how the dominant follicle in the ovarian cycle is selected, as well as the effectiveness of hormone secretion responsible for encoding the frequency of occurrence of periodic signals. The book also discusses heart signal sources such as cardiac dynamics and the response of periodically excited cardiac cells. The text can prove valuable for practioners in the field of neurology and cardiovascular medicine, and for researchers in molecular biology and molecular chemistry.
Download or read book Evolution of Extracellular Matrix written by Fred W. Keeley and published by Springer Science & Business Media. This book was released on 2013-03-15 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: The evolution of single cells into multicellular organisms was mediated, in large part, by the extracellular matrix. The proteins and glycoconjugates that make up the extracellular matrix provide structural support to cellular complexes, facilitate cell adhesion and migration, and impart mechanical properties that are important for tissue function. Each class of ECM macromolecule has evolved to incorporate distinctive properties that are defined by conserved modules that are mixed together to achieve appropriate function. This volume provides a comprehensive analysis of how the major ECM components evolved over time in order to fill their specific roles found in modern organisms. The major focus is on the structural matrix proteins, matricellular proteins, and more complex ECM structures such as basement membranes. Adhesive proteins and their receptors are also discussed.
Download or read book Randomness in Evolution written by John Tyler Bonner and published by Princeton University Press. This book was released on 2013-03-24 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: John Tyler Bonner here challenges a central tenet of evolutionary biology.
Download or read book Pharmacoepigenetics written by Ramón Cacabelos and published by Academic Press. This book was released on 2019-06-04 with total page 986 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmacoepigenetics provides a comprehensive volume on the role of epigenetics and epigenomics in drug discovery and development, providing a detailed, but accessible, view of the field, from basic principles, to applications in disease therapeutics. Leading international researchers from across academia, clinical settings and the pharmaceutical industry discuss the influence of epigenetics and epigenomics in human pathology, epigenetic biomarkers for disease prediction, diagnosis, and treatment, current epigenetic drugs, and the application of epigenetic procedures in drug development. Throughout the book, chapter authors offer a balanced and objective discussion of the future of pharmacoepigenetics and its crucial contribution to the growth of precision and personalized medicine. - Fully examines the influence of epigenetics and epigenomics in human pathology, epigenetic biomarkers for disease prediction, diagnosis, treatment, current epigenetic drugs and the application of epigenetic procedures in drug development - Features chapter contributions from leading international researchers in academia, clinical settings and the pharmaceutical industry - Instructs researchers, students and clinicians on how to better interpret and employ pharmacoepigenetics in drug development, efficiency and safety - Provides a balanced and objective discussion of the future of pharmacoepigenetics and its crucial role in precision medicine
