Download or read book Modern Medical Statistics written by Brian S. Everitt and published by Wiley. This book was released on 2010-06-28 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Statistical science plays an increasingly important role in medical research. Over the last few decades, many new statistical methods have been developed which have particular relevance for medical researchers and, with the appropriate software now easily available, these techniques can be used almost routinely to great effect. These innovative methods include survival analysis, generalized additive models and Bayesian methods. Modern Medical Statistics covers these essential new techniques at an accessible technical level, its main focus being not on the theory but on the effective practical application of these methods in medical research. Modern Medical Statistics is an indispensable practical guide for medical researchers and medical statisticians as well as an ideal text for advanced courses in medical statistics and public health.
Download or read book Statistics at Square Two written by Michael J. Campbell and published by John Wiley & Sons. This book was released on 2013-07-03 with total page 1 pages. Available in PDF, EPUB and Kindle. Book excerpt: Updated companion volume to the ever popular Statistics at Square One (SS1) Statistics at Square Two, Second Edition, helps you evaluate the many statistical methods in current use. Going beyond the basics of SS1, it covers sophisticated methods and highlights misunderstandings. Easy to read, it includes annotated computer outputs and keeps formulas to a minimum. Worked examples of methods such as multiple and logical regression reinforce the text. Each chapter concludes with exercises to stimulate learning. All those who need to understand statistics in clinical research papers and apply them in their own research will value this compact and coherent guide.
Download or read book Modern Statistics for the Life Sciences written by Alan Grafen and published by Oxford University Press. This book was released on 2002-03-21 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Model formulae represent a powerful methodology for describing, discussing, understanding, and performing that large part of statistical tests known as linear statistics. The book aims to put this methodology firmly within the grasp of undergraduates.
Download or read book Modern Applied U Statistics written by Jeanne Kowalski and published by John Wiley & Sons. This book was released on 2008-01-28 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: A timely and applied approach to the newly discovered methods and applications of U-statistics Built on years of collaborative research and academic experience, Modern Applied U-Statistics successfully presents a thorough introduction to the theory of U-statistics using in-depth examples and applications that address contemporary areas of study including biomedical and psychosocial research. Utilizing a "learn by example" approach, this book provides an accessible, yet in-depth, treatment of U-statistics, as well as addresses key concepts in asymptotic theory by integrating translational and cross-disciplinary research. The authors begin with an introduction of the essential and theoretical foundations of U-statistics such as the notion of convergence in probability and distribution, basic convergence results, stochastic Os, inference theory, generalized estimating equations, as well as the definition and asymptotic properties of U-statistics. With an emphasis on nonparametric applications when and where applicable, the authors then build upon this established foundation in order to equip readers with the knowledge needed to understand the modern-day extensions of U-statistics that are explored in subsequent chapters. Additional topical coverage includes: Longitudinal data modeling with missing data Parametric and distribution-free mixed-effect and structural equation models A new multi-response based regression framework for non-parametric statistics such as the product moment correlation, Kendall's tau, and Mann-Whitney-Wilcoxon rank tests A new class of U-statistic-based estimating equations (UBEE) for dependent responses Motivating examples, in-depth illustrations of statistical and model-building concepts, and an extensive discussion of longitudinal study designs strengthen the real-world utility and comprehension of this book. An accompanying Web site features SAS? and S-Plus? program codes, software applications, and additional study data. Modern Applied U-Statistics accommodates second- and third-year students of biostatistics at the graduate level and also serves as an excellent self-study for practitioners in the fields of bioinformatics and psychosocial research.
Download or read book Modern Statistics for Modern Biology written by SUSAN. HUBER HOLMES (WOLFGANG.) and published by Cambridge University Press. This book was released on 2018 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Medical Statistics written by Jennifer Peat and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Holistic approach to understanding medical statistics This hands-on guide is much more than a basic medical statistics introduction. It equips you with the statistical tools required for evidence-based clinical research. Each chapter provides a clear step-by-step guide to each statistical test with practical instructions on how to generate and interpret the numbers, and present the results as scientific tables or graphs. Showing you how to: analyse data with the help of data set examples (Click here to download datasets) select the correct statistics and report results for publication or presentation understand and critically appraise results reported in the literature Each statistical test is linked to the research question and the type of study design used. There are also checklists for critically appraising the literature and web links to useful internet sites. Clear and concise explanations, combined with plenty of examples and tabulated explanations are based on the authors’ popular medical statistics courses. Critical appraisal guidelines at the end of each chapter help the reader evaluate the statistical data in their particular contexts.
Download or read book The Rise and Fall of Modern Medicine written by James Le Fanu and published by Carroll & Graf Pub. This book was released on 2000 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: Argues that the pace of medical discoveries has slowed in the last twenty-five years due to excessive emphasis on the social and political aspects of health care, and to controversies caused by ethical issues.
Download or read book Clinical Prediction Models written by Ewout W. Steyerberg and published by Springer. This book was released on 2019-07-22 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of this volume provides insight and practical illustrations on how modern statistical concepts and regression methods can be applied in medical prediction problems, including diagnostic and prognostic outcomes. Many advances have been made in statistical approaches towards outcome prediction, but a sensible strategy is needed for model development, validation, and updating, such that prediction models can better support medical practice. There is an increasing need for personalized evidence-based medicine that uses an individualized approach to medical decision-making. In this Big Data era, there is expanded access to large volumes of routinely collected data and an increased number of applications for prediction models, such as targeted early detection of disease and individualized approaches to diagnostic testing and treatment. Clinical Prediction Models presents a practical checklist that needs to be considered for development of a valid prediction model. Steps include preliminary considerations such as dealing with missing values; coding of predictors; selection of main effects and interactions for a multivariable model; estimation of model parameters with shrinkage methods and incorporation of external data; evaluation of performance and usefulness; internal validation; and presentation formatting. The text also addresses common issues that make prediction models suboptimal, such as small sample sizes, exaggerated claims, and poor generalizability. The text is primarily intended for clinical epidemiologists and biostatisticians. Including many case studies and publicly available R code and data sets, the book is also appropriate as a textbook for a graduate course on predictive modeling in diagnosis and prognosis. While practical in nature, the book also provides a philosophical perspective on data analysis in medicine that goes beyond predictive modeling. Updates to this new and expanded edition include: • A discussion of Big Data and its implications for the design of prediction models • Machine learning issues • More simulations with missing ‘y’ values • Extended discussion on between-cohort heterogeneity • Description of ShinyApp • Updated LASSO illustration • New case studies
Download or read book The Fundamentals of Modern Statistical Genetics written by Nan M. Laird and published by Springer Science & Business Media. This book was released on 2010-12-13 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the statistical models and methods that are used to understand human genetics, following the historical and recent developments of human genetics. Starting with Mendel’s first experiments to genome-wide association studies, the book describes how genetic information can be incorporated into statistical models to discover disease genes. All commonly used approaches in statistical genetics (e.g. aggregation analysis, segregation, linkage analysis, etc), are used, but the focus of the book is modern approaches to association analysis. Numerous examples illustrate key points throughout the text, both of Mendelian and complex genetic disorders. The intended audience is statisticians, biostatisticians, epidemiologists and quantitatively- oriented geneticists and health scientists wanting to learn about statistical methods for genetic analysis, whether to better analyze genetic data, or to pursue research in methodology. A background in intermediate level statistical methods is required. The authors include few mathematical derivations, and the exercises provide problems for students with a broad range of skill levels. No background in genetics is assumed.
Download or read book Modern Directional Statistics written by Christophe Ley and published by CRC Press. This book was released on 2017-08-03 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern Directional Statistics collects important advances in methodology and theory for directional statistics over the last two decades. It provides a detailed overview and analysis of recent results that can help both researchers and practitioners. Knowledge of multivariate statistics eases the reading but is not mandatory. The field of directional statistics has received a lot of attention over the past two decades, due to new demands from domains such as life sciences or machine learning, to the availability of massive data sets requiring adapted statistical techniques, and to technological advances. This book covers important progresses in distribution theory,high-dimensional statistics, kernel density estimation, efficient inference on directional supports, and computational and graphical methods. Christophe Ley is professor of mathematical statistics at Ghent University. His research interests include semi-parametrically efficient inference, flexible modeling, directional statistics and the study of asymptotic approximations via Stein’s Method. His achievements include the Marie-Jeanne Laurent-Duhamel prize of the Société Française de Statistique and an elected membership at the International Statistical Institute. He is associate editor for the journals Computational Statistics & Data Analysis and Econometrics and Statistics. Thomas Verdebout is professor of mathematical statistics at Université libre de Bruxelles (ULB). His main research interests are semi-parametric statistics, high- dimensional statistics, directional statistics and rank-based procedures. He has won an annual prize of the Belgian Academy of Sciences and is an elected member of the International Statistical Institute. He is associate editor for the journals Statistics and Probability Letters and Journal of Multivariate Analysis.
Download or read book Medical Uses of Statistics Second Edition written by Bailar/Mostelle and published by CRC Press. This book was released on 1992-03-01 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explains the purpose of statistical methods in medical studies & analyzes the statistical techniques used by clinical investigators, with special emphasis on studies published in The New England Journal of Medicine. Clarifies fundamental concepts of statistical design & analysis & facilitates the understanding of research results.
Download or read book Evidence Based Medicine and the Changing Nature of Health Care written by Institute of Medicine and published by National Academies Press. This book was released on 2008-09-06 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drawing on the work of the Roundtable on Evidence-Based Medicine, the 2007 IOM Annual Meeting assessed some of the rapidly occurring changes in health care related to new diagnostic and treatment tools, emerging genetic insights, the developments in information technology, and healthcare costs, and discussed the need for a stronger focus on evidence to ensure that the promise of scientific discovery and technological innovation is efficiently captured to provide the right care for the right patient at the right time. As new discoveries continue to expand the universe of medical interventions, treatments, and methods of care, the need for a more systematic approach to evidence development and application becomes increasingly critical. Without better information about the effectiveness of different treatment options, the resulting uncertainty can lead to the delivery of services that may be unnecessary, unproven, or even harmful. Improving the evidence-base for medicine holds great potential to increase the quality and efficiency of medical care. The Annual Meeting, held on October 8, 2007, brought together many of the nation's leading authorities on various aspects of the issues - both challenges and opportunities - to present their perspectives and engage in discussion with the IOM membership.
Download or read book Principles of Medical Statistics written by Austin Bradford Hill and published by . This book was released on 1949 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Happy Accidents written by Morton A. Meyers and published by Skyhorse Publishing Inc.. This book was released on 2011-09 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: Afascinating and highly accessible look at the surprising role serendipity has played in some of the most important medical discoveries in the twentieth...
Download or read book Modern Statistical Methods for Spatial and Multivariate Data written by Norou Diawara and published by Springer. This book was released on 2019-06-29 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: This contributed volume features invited papers on current models and statistical methods for spatial and multivariate data. With a focus on recent advances in statistics, topics include spatio-temporal aspects, classification techniques, the multivariate outcomes with zero and doubly-inflated data, discrete choice modelling, copula distributions, and feasible algorithmic solutions. Special emphasis is placed on applications such as the use of spatial and spatio-temporal models for rainfall in South Carolina and the multivariate sparse areal mixed model for the Census dataset for the state of Iowa. Articles use simulated and aggregated data examples to show the flexibility and wide applications of proposed techniques. Carefully peer-reviewed and pedagogically presented for a broad readership, this volume is suitable for graduate and postdoctoral students interested in interdisciplinary research. Researchers in applied statistics and sciences will find this book an important resource on the latest developments in the field. In keeping with the STEAM-H series, the editors hope to inspire interdisciplinary understanding and collaboration.
Download or read book OpenIntro Statistics written by David Diez and published by . This book was released on 2015-07-02 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The OpenIntro project was founded in 2009 to improve the quality and availability of education by producing exceptional books and teaching tools that are free to use and easy to modify. We feature real data whenever possible, and files for the entire textbook are freely available at openintro.org. Visit our website, openintro.org. We provide free videos, statistical software labs, lecture slides, course management tools, and many other helpful resources.
Download or read book Modern Medical Guide written by Harold Shryock and published by . This book was released on 1990 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt: