Download or read book Biological Clocks Rhythms and Oscillations written by Daniel B. Forger and published by MIT Press. This book was released on 2024-08-06 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: An introduction to the mathematical, computational, and analytical techniques used for modeling biological rhythms, presenting tools from many disciplines and example applications. All areas of biology and medicine contain rhythms, and these behaviors are best understood through mathematical tools and techniques. This book offers a survey of mathematical, computational, and analytical techniques used for modeling biological rhythms, gathering these methods for the first time in one volume. Drawing on material from such disciplines as mathematical biology, nonlinear dynamics, physics, statistics, and engineering, it presents practical advice and techniques for studying biological rhythms, with a common language. The chapters proceed with increasing mathematical abstraction. Part I, on models, highlights the implicit assumptions and common pitfalls of modeling, and is accessible to readers with basic knowledge of differential equations and linear algebra. Part II, on behaviors, focuses on simpler models, describing common properties of biological rhythms that range from the firing properties of squid giant axon to human circadian rhythms. Part III, on mathematical techniques, guides readers who have specific models or goals in mind. Sections on “frontiers” present the latest research; “theory” sections present interesting mathematical results using more accessible approaches than can be found elsewhere. Each chapter offers exercises. Commented MATLAB code is provided to help readers get practical experience. The book, by an expert in the field, can be used as a textbook for undergraduate courses in mathematical biology or graduate courses in modeling biological rhythms and as a reference for researchers.

Download or read book Simulation and Verification of Electronic and Biological Systems written by Peng Li and published by Springer Science & Business Media. This book was released on 2011-01-12 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: Simulation and Verification of Electronic and Biological Systems provides a showcase for the Circuit and Multi-Domain Simulation Workshop held in San Jose, California, USA, on November 5, 2009. The nine chapters are contributed by experts in the field and provide a broad discussion of recent developments on simulation, modeling and verification of integrated circuits and biological systems. Specific topics include large scale parallel circuit simulation, industrial practice of fast SPICE simulation, structure-preserving model order reduction of interconnects, advanced simulation techniques for oscillator networks, dynamic stability of static memories and biological systems as well as verification of analog integrated circuits. Simulation and verification are fundamental enablers for understanding, analyzing and designing an extremely broad range of engineering and biological circuits and systems. The design of nanometer integrated electronic systems and emerging biomedical applications have stimulated the development of novel simulation and verification techniques and methodologies. Simulation and Verification of Electronic and Biological Systems provides a broad discussion of recent advances on simulation, modeling and verification of integrated circuits and biological systems and offers a basis for stimulating new innovations.

Download or read book A First Guide to Computational Modelling in Physics written by Pawel Scharoch and published by Cambridge University Press. This book was released on 2024-01-31 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt: Early-stage physics and engineering students will take an innovative, project-based approach, teaching them to apply numerical methods.

Download or read book From Clocks to Chaos written by Leon Glass and published by Princeton University Press. This book was released on 2020-11-10 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: In an important new contribution to the literature of chaos, two distinguished researchers in the field of physiology probe central theoretical questions about physiological rhythms. Topics discussed include: How are rhythms generated? How do they start and stop? What are the effects of perturbation of the rhythms? How are oscillations organized in space? Leon Glass and Michael Mackey address an audience of biological scientists, physicians, physical scientists, and mathematicians, but the work assumes no knowledge of advanced mathematics. Variation of rhythms outside normal limits, or appearance of new rhythms where none existed previously, are associated with disease. One of the most interesting features of the book is that it makes a start at explaining "dynamical diseases" that are not the result of infection by pathogens but that stem from abnormalities in the timing of essential functions. From Clocks to Chaos provides a firm foundation for understanding dynamic processes in physiology.

Download or read book Modeling Life written by Alan Garfinkel and published by Springer. This book was released on 2017-09-06 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book develops the mathematical tools essential for students in the life sciences to describe interacting systems and predict their behavior. From predator-prey populations in an ecosystem, to hormone regulation within the body, the natural world abounds in dynamical systems that affect us profoundly. Complex feedback relations and counter-intuitive responses are common in nature; this book develops the quantitative skills needed to explore these interactions. Differential equations are the natural mathematical tool for quantifying change, and are the driving force throughout this book. The use of Euler’s method makes nonlinear examples tractable and accessible to a broad spectrum of early-stage undergraduates, thus providing a practical alternative to the procedural approach of a traditional Calculus curriculum. Tools are developed within numerous, relevant examples, with an emphasis on the construction, evaluation, and interpretation of mathematical models throughout. Encountering these concepts in context, students learn not only quantitative techniques, but how to bridge between biological and mathematical ways of thinking. Examples range broadly, exploring the dynamics of neurons and the immune system, through to population dynamics and the Google PageRank algorithm. Each scenario relies only on an interest in the natural world; no biological expertise is assumed of student or instructor. Building on a single prerequisite of Precalculus, the book suits a two-quarter sequence for first or second year undergraduates, and meets the mathematical requirements of medical school entry. The later material provides opportunities for more advanced students in both mathematics and life sciences to revisit theoretical knowledge in a rich, real-world framework. In all cases, the focus is clear: how does the math help us understand the science?

Download or read book Dynamic Systems Biology Modeling and Simulation written by Joseph DiStefano III and published by Academic Press. This book was released on 2015-01-10 with total page 886 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dynamic Systems Biology Modeling and Simuation consolidates and unifies classical and contemporary multiscale methodologies for mathematical modeling and computer simulation of dynamic biological systems – from molecular/cellular, organ-system, on up to population levels. The book pedagogy is developed as a well-annotated, systematic tutorial – with clearly spelled-out and unified nomenclature – derived from the author's own modeling efforts, publications and teaching over half a century. Ambiguities in some concepts and tools are clarified and others are rendered more accessible and practical. The latter include novel qualitative theory and methodologies for recognizing dynamical signatures in data using structural (multicompartmental and network) models and graph theory; and analyzing structural and measurement (data) models for quantification feasibility. The level is basic-to-intermediate, with much emphasis on biomodeling from real biodata, for use in real applications. - Introductory coverage of core mathematical concepts such as linear and nonlinear differential and difference equations, Laplace transforms, linear algebra, probability, statistics and stochastics topics - The pertinent biology, biochemistry, biophysics or pharmacology for modeling are provided, to support understanding the amalgam of "math modeling with life sciences - Strong emphasis on quantifying as well as building and analyzing biomodels: includes methodology and computational tools for parameter identifiability and sensitivity analysis; parameter estimation from real data; model distinguishability and simplification; and practical bioexperiment design and optimization - Companion website provides solutions and program code for examples and exercises using Matlab, Simulink, VisSim, SimBiology, SAAMII, AMIGO, Copasi and SBML-coded models - A full set of PowerPoint slides are available from the author for teaching from his textbook. He uses them to teach a 10 week quarter upper division course at UCLA, which meets twice a week, so there are 20 lectures. They can easily be augmented or stretched for a 15 week semester course - Importantly, the slides are editable, so they can be readily adapted to a lecturer's personal style and course content needs. The lectures are based on excerpts from 12 of the first 13 chapters of DSBMS. They are designed to highlight the key course material, as a study guide and structure for students following the full text content - The complete PowerPoint slide package (~25 MB) can be obtained by instructors (or prospective instructors) by emailing the author directly, at: [email protected]

Download or read book Computational Methods in Systems Biology written by Corrado Priami and published by Springer Science & Business Media. This book was released on 2003-02-07 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rovereto,December2002 CorradoPriami ProgrammeCommitteeofCMSB 2003 CorradoPriami(Chair),UniversityofTrento(Italy), CharlesAu?ray,CNRS,Villejuif(France), CosimaBaldari,Universit`adiSiena(Italy), AlexanderBockmayr,Universit ́eHenriPoincar ́e(France), LucaCardelli,MicrosoftResearchCambridge(UK), VincentDanos,Universit ́eParisVII(France), PierpaoloDegano,Universitad ` iPisa(Italy), Francois ̧ Fages,INRIA,Rocquencourt(France), DrabløsFinn,NorwegianUniversityofScienceandTechnology,Trondheim(N- way), MonikaHeiner,BrandenburgUniversityofTechnologyatCottbus(Germany), InaKoch,UniversityofAppliedSciencesBerlin,(Germany), JohnE.

Download or read book Mathematical Approaches to Biological Systems written by Toru Ohira and published by Springer. This book was released on 2015-03-18 with total page 171 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the most recent mathematical approaches to the growing research area of networks, oscillations, and collective motions in the context of biological systems. Bringing together the results of multiple studies of different biological systems, this book sheds light on the relations among these research themes. Included in this book are the following topics: feedback systems with time delay and threshold of sensing (dead zone), robustness of biological networks from the point of view of dynamical systems, the hardware-oriented neuron modeling approach, a universal mechanism governing the entrainment limit under weak forcing, the robustness mechanism of open complex systems, situation-dependent switching of the cues primarily relied on by foraging ants, and group chase and escape. Research on different biological systems is presented together, not separated by specializations or by model systems. Therefore, the book provides diverse perspectives at the forefront of current mathematical research on biological systems, especially focused on networks, oscillations, and collective motions. This work is aimed at advanced undergraduate, graduate, and postdoctoral students, as well as scientists and engineers. It will also be of great use for professionals in industries and service sectors owing to the applicability of topics such as networks and synchronizations.

Download or read book Quantum Mechanical Simulation Methods for Studying Biological Systems written by Dominique Bicout and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is now generally agreed that a deeper understanding of biological processes requires a multi-disciplinary approach employing the tools of biology, chemistry, and physics. Such understanding involves study of biomacromolecules and their functions, which includes how they interact, their reactions, and how information is transmitted between them. This volume is devoted to quantum mechanical simulation techniques, which have developed rapidly in recent years. It covers quantum mechanical calculations of large systems, molecular dynamics combining quantum and classical algorithms, quantum dynamical simulations, and electron and proton transfer processes in proteins and in solutions.

Download or read book Modelling and Control in Biomedical Systems 1997 including Biological Systems written by D. A. Linkens and published by Pergamon. This book was released on 1997 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: Paperback. This volume contains the 90 papers presented at the 3rd IFAC Symposium on Modelling and Control in Biomedical Systems held in Warwick, UK from 23-26 March 1997. Significant work in the field of biomedical systems analysis and design is taking place throughout the world and the opportunities for technological interchanges offered by symposia like this one are extremely valuable for the progress and stability of effort and vision in this important human-centred field.The symposium was multi- and inter-disciplinary in nature with the choice of topics solicited covering the major systems' components and functions of complex physiology. The remit was also extended, on this occasion, beyond mammalian physiology to that of biological systems. Therefore, a special session was devoted to the modelling and control of botanical systems with the aim of providing an exchange of ideas with biomathematicians.

Download or read book Mathematical Biology written by James D. Murray and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 783 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mathematics has always benefited from its involvement with developing sciences. Each successive interaction revitalises and enhances the field. Biomedical science is clearly the premier science of the foreseeable future. For the continuing health of their subject mathematicians must become involved with biology. With the example of how mathematics has benefited from and influenced physics, it is clear that if mathematicians do not become involved in the biosciences they will simply not be a part of what are likely to be the most important and exciting scientific discoveries of all time. Mathematical biology is a fast growing, well recognised, albeit not clearly defined, subject and is, to my mind, the most exciting modern application of mathematics. The increasing use of mathematics in biology is inevitable as biol ogy becomes more quantitative. The complexity of the biological sciences makes interdisciplinary involvement essential. For the mathematician, biology opens up new and exciting branches while for the biologist mathematical modelling offers another research tool commmensurate with a new powerful laboratory technique but only if used appropriately and its limitations recognised. However, the use of esoteric mathematics arrogantly applied to biological problems by mathemati cians who know little about the real biology, together with unsubstantiated claims as to how important such theories are, does little to promote the interdisciplinary involvement which is so essential. Mathematical biology research, to be useful and interesting, must be relevant biologically.

Download or read book Formal Modeling and Analysis of Timed Systems written by Nathalie Bertrand and published by Springer Nature. This book was released on 2020-08-25 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 18th International Conference on Formal Modeling and Analysis of Timed Systems, FORMATS 2020, held in Vienna, Austria, in September 2020. The 16 full papers and 2 short papers presented in this volume were carefully reviewed and selected from 42 submissions. The papers focus on topics such as foundations and semantics, methods and tools, techniques, algorithms, data structures, and software tools for analyzing timed systems and resolving temporal constraints. Due to the Corona pandemic this conference was held as a virtual event.

Download or read book Modeling Simulation and Optimization written by Shkelzen Cakaj and published by BoD – Books on Demand. This book was released on 2010-03-01 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book presents a collection of chapters dealing with a wide selection of topics concerning different applications of modeling. It includes modeling, simulation and optimization applications in the areas of medical care systems, genetics, business, ethics and linguistics, applying very sophisticated methods. Algorithms, 3-D modeling, virtual reality, multi objective optimization, finite element methods, multi agent model simulation, system dynamics simulation, hierarchical Petri Net model and two level formalism modeling are tools and methods employed in these papers.

Download or read book Musical Communication written by Dorothy Miell and published by Oxford University Press, USA. This book was released on 2005 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Bringing together leading researchers from a variety of academic and applied backgrounds, this book examines how music can be used to communicate, as well as the biological, cognitive, social, and cultural processes which underlie such communication."--BOOK JACKET.

Download or read book Coupled Oscillator Based Active Array Antennas written by Ronald J. Pogorzelski and published by John Wiley & Sons. This book was released on 2012-07-18 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Describing an innovative approach to phased-array control in antenna design This book explores in detail phased-array antennas that use coupled-oscillator arrays, an arrangement featuring a remarkably simple beam steering control system and a major reduction in complexity compared with traditional methods of phased-array control. It brings together in one convenient, self-contained volume the many salient research results obtained over the past ten to fifteen years in laboratories around the world, including the California Institute of Technology's Jet Propulsion Laboratory. The authors examine the underlying theoretical framework of coupled-oscillator systems, clearly explaining the linear and nonlinear formalisms used in the development of coupled-oscillator arrays, while introducing a variety of state-of-the-art methodologies, design solutions, and tools for applying this control scheme. Readers will find: Numerous implementation examples of coupled-oscillator array prototypes A continuum model that permits application of diffusion theory to the analysis of phase dynamics A demonstration of the array behavior through experimental results that validate the linearized theory Examples of how incorporating coupling delay restores causality, including the latest published results Guidance on how to accurately analyze and optimize coupled-oscillator arrays using modern simulation tools A review of current developments, including the design of compact couple-oscillator array antennas Complete with 150 diagrams and photographs, Coupled-Oscillator Based Active-Array Antennas is a highly useful tutorial for antenna designers and a valuable reference for researchers and engineers wishing to learn about this cutting-edge technology.

Download or read book Advances in Biologically Inspired Information Systems written by Falko Dressler and published by Springer Science & Business Media. This book was released on 2007-07-09 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Technology is taking us to a world where myriads of networked devices interact with the physical world in multiple ways and at multiple scales. This book presents a comprehensive overview of the most promising research directions in the area of bio-inspired computing. According to the broad spectrum addressed by the different chapters, a rich variety of biological principles and their application to ICT systems are presented.

Download or read book Topics In Nonlinear Dynamics Applications To Physics Biology And Economic Systems written by Erik Mosekilde and published by World Scientific. This book was released on 1997-01-04 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: Through a series of examples from physics, engineering, biology and economics, this book illustrates the enormous potential for application of ideas and concepts from nonlinear dynamics and chaos theory. The overlap with examples published in other books is virtually equal to zero. The book takes the reader from detailed studies of bifurcation structures of relativity simple models to pattern formation in spatially extended systems. The book also discusses the different perspectives that nonlinear dynamics brings to different fields of science.