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Book Modeling Sensorineural Hearing Loss

Download or read book Modeling Sensorineural Hearing Loss written by Walt Jesteadt and published by Routledge. This book was released on 2019-01-04 with total page 731 pages. Available in PDF, EPUB and Kindle. Book excerpt: A recent study indicates that 20 million people in the United States have significant sensorineural hearing loss. Approximately 95% of those people have partial losses, with varying degrees of residual hearing. These percentages are similar in other developed countries. What changes in the function of the cochlea or inner ear cause such losses? What does the world sound like to the 19 million people with residual hearing? How should we transform sounds to correct for the hearing loss and maximize restoration of normal hearing? Answers to such questions require detailed models of the way that sounds are processed by the nervous system, both for listeners with normal hearing and for those with sensorineural hearing loss. This book contains chapters describing the work of 25 different research groups. A great deal of research in recent years has been aimed at obtaining a better physiological description of the altered processes that cause sensorineural hearing loss and a better understanding of transformations that occur in the perception of those sounds that are sufficiently intense that they can still be heard. Efforts to understand these changes in function have lead to a better understanding of normal function as well. This research has been based on rigorous mathematical models, computer simulations of mechanical and physiological processes, and signal processing simulations of the altered perceptual experience of listeners with sensorineural hearing loss. This book provides examples of all these approaches to modeling sensorineural hearing loss and a summary of the latest research in the field.

Book Psychoacoustics

    Book Details:
  • Author : Jennifer J. Lentz
  • Publisher : Plural Publishing
  • Release : 2023-11-27
  • ISBN : 1635504392
  • Pages : 305 pages

Download or read book Psychoacoustics written by Jennifer J. Lentz and published by Plural Publishing. This book was released on 2023-11-27 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: Psychoacoustics: Auditory Perception of Listeners with Normal Hearing and Hearing Loss, Second Edition provides an overview of the field of psychoacoustics, with a primary focus on auditory perception. The book retains its focus on applications of psychoacoustics to clinical audiology, and its modular organization, with each chapter including relevant information around a specific topic. Within each chapter, acoustics, physiology, and perception by adult listeners with normal hearing and those with hearing loss, as they relate to that topic, are presented. The influence of hearing loss on these general auditory abilities is discussed in every chapter. Components of the book also include the role of psychoacoustics in audiological assessment and treatment. The text is ideal for audiology students who intend on having a clinical career and need an understanding of both normal and impaired auditory perception. It is intended to give students sufficient information to understand how the ear achieves auditory perception, what the capabilities of the ear are, and how hearing loss influences that perception. It also provides students with a foundation for further study in the area and to apply psychoacoustic principles to diagnostic audiology and audiological rehabilitation. New to the Second Edition: * 70 new figures to clarify some points and facilitate students’ understanding of the material * New chapter that focuses exclusively on the perception by individuals wearing hearing aids and cochlear implants * New section on the perceptual consequences of sensorineural hearing loss on everyday listening added to each chapter * Revamped chapter on Psychoacoustics and Advanced Clinical Auditory Assessment now solely addresses elements within diagnostic audiology that are based on psychoacoustics, with added content on tinnitus assessment, automated (Békésy) audiometry, retrocochlear and pseudohypacusis evaluation, and the identification of dead regions * Enhanced focus on inclusivity, such as alternative versions of some demonstrations designed to be more accessible to individuals with hearing loss, and a new section on the contributions of women and BIPOC scientists to the field of psychoacoustics Key Features: * Learning objectives and summaries begin and end each chapter to convey the goals of the text and review student comprehension * Each chapter contains exercises designed to develop critical thinking about psychoacoustics * Chapters include the following: introduction, relevant acoustics, important physiological studies, perception by normal-hearing listeners, and perception by listeners who have sensorineural hearing loss * Emphasis on applied learning for more effective and efficient learning of the material Disclaimer: Please note that ancillary content such as lab exercises are not included as published in the original print version of this book.

Book Modeling Sensorineural Hearing Loss

Download or read book Modeling Sensorineural Hearing Loss written by Walt Jesteadt and published by Routledge. This book was released on 2019-01-04 with total page 515 pages. Available in PDF, EPUB and Kindle. Book excerpt: A recent study indicates that 20 million people in the United States have significant sensorineural hearing loss. Approximately 95% of those people have partial losses, with varying degrees of residual hearing. These percentages are similar in other developed countries. What changes in the function of the cochlea or inner ear cause such losses? What does the world sound like to the 19 million people with residual hearing? How should we transform sounds to correct for the hearing loss and maximize restoration of normal hearing? Answers to such questions require detailed models of the way that sounds are processed by the nervous system, both for listeners with normal hearing and for those with sensorineural hearing loss. This book contains chapters describing the work of 25 different research groups. A great deal of research in recent years has been aimed at obtaining a better physiological description of the altered processes that cause sensorineural hearing loss and a better understanding of transformations that occur in the perception of those sounds that are sufficiently intense that they can still be heard. Efforts to understand these changes in function have lead to a better understanding of normal function as well. This research has been based on rigorous mathematical models, computer simulations of mechanical and physiological processes, and signal processing simulations of the altered perceptual experience of listeners with sensorineural hearing loss. This book provides examples of all these approaches to modeling sensorineural hearing loss and a summary of the latest research in the field.

Book Sourcebook of Models for Biomedical Research

Download or read book Sourcebook of Models for Biomedical Research written by P. Michael Conn and published by Springer Science & Business Media. This book was released on 2008 with total page 756 pages. Available in PDF, EPUB and Kindle. Book excerpt: The collection of systems represented in Sourcebook of genomic programs, although this work is certainly well Models for Biomedical Research is an effort to re?ect the represented and indexed. diversity and utility of models that are used in biomedicine. Some models have been omitted due to page limitations That utility is based on the consideration that observations and we have encouraged the authors to use tables and made in particular organisms will provide insight into the ? gures to make comparisons of models so that observations workings of other, more complex, systems. Even the cell not available in primary publications can become useful to cycle in the simple yeast cell has similarities to that in the reader. humans and regulation with similar proteins occurs. We thank Richard Lansing and the staff at Humana for Some models have the advantage that the reproductive, guidance through the publication process. mitotic, development or aging cycles are rapid compared As this book was entering production, we learned of the with those in humans; others are utilized because individual loss of Tom Lanigan, Sr. Tom was a leader and innovator proteins may be studied in an advantageous way and that in scienti?c publishing and a good friend and colleague to have human homologs. Other organisms are facile to grow all in the exploratory enterprise. We dedicate this book to in laboratory settings or lend themselves to convenient analy- his memory. We will miss him greatly.

Book Hearing Loss

    Book Details:
  • Author : National Research Council
  • Publisher : National Academies Press
  • Release : 2004-12-17
  • ISBN : 0309092965
  • Pages : 321 pages

Download or read book Hearing Loss written by National Research Council and published by National Academies Press. This book was released on 2004-12-17 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: Millions of Americans experience some degree of hearing loss. The Social Security Administration (SSA) operates programs that provide cash disability benefits to people with permanent impairments like hearing loss, if they can show that their impairments meet stringent SSA criteria and their earnings are below an SSA threshold. The National Research Council convened an expert committee at the request of the SSA to study the issues related to disability determination for people with hearing loss. This volume is the product of that study. Hearing Loss: Determining Eligibility for Social Security Benefits reviews current knowledge about hearing loss and its measurement and treatment, and provides an evaluation of the strengths and weaknesses of the current processes and criteria. It recommends changes to strengthen the disability determination process and ensure its reliability and fairness. The book addresses criteria for selection of pure tone and speech tests, guidelines for test administration, testing of hearing in noise, special issues related to testing children, and the difficulty of predicting work capacity from clinical hearing test results. It should be useful to audiologists, otolaryngologists, disability advocates, and others who are concerned with people who have hearing loss.

Book The Micro Vasculature of the Cochlea

Download or read book The Micro Vasculature of the Cochlea written by Mattia Carraro and published by . This book was released on 2016 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis concerns the role of cochlear microvasculature in normal hearing function and in pathological conditions that result in hearing loss. In animal models we have investigated two major types of sensorineural hearing loss where degeneration of the stria vascularis has been implicated, namely presbyacusis and hearing loss associated with cytomegalovirus (CMV) infection. The former eventual affects all aging humans; the latter is a common etiology for congenital hearing loss in infants. The focus of experimental work is on the capillary networks of the cochlea. We chose to use corrosion cast techniques to visualize and quantify capillary vessel parameters. For the small and delicate cochleas of our mouse models, this required extensive technical improvements to corrosion casting methodology. These innovations proved successful. Three experimental animal model studies were made. The first involved analysis, and modeling of strial feeding arterioles in normal subject. The hypothesis posed was that the highly convoluted structure of these vessels acts to dampen cardiovascular pulsations within the cochlea and thereby prevent self-stimulation by such biological noise. The results from this study support the hypothesis. In our murine models of presbyacusis and of CMV infection we correlated loss of auditory thresholds measured with ABR methods, with degenerative changes to cochlear microvasculature. In mice with age-related, high frequency hearing loss, we report significant vascular degeneration of stria vascularis in basal (high frequency) cochlear areas compared to more apical regions. After CMV infection in newborn mice, we observed at 6 weeks a wide range of auditory threshold changes. At 8 weeks post-infection, the cochleas had suffered a wide range of vascular damage. The most vulnerable structure was stria vascularis in the mid-apical cochlear turn. Our novel finding that vascular damage is the primary lesion after CMV infection is consistent with some clinical characteristics of this hearing loss type in infants.

Book Computational Models of the Auditory System

Download or read book Computational Models of the Auditory System written by Ray Meddis and published by Springer Science & Business Media. This book was released on 2010-06-16 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Springer Handbook of Auditory Research presents a series of comprehensive and synthetic reviews of the fundamental topics in modern auditory research. The v- umes are aimed at all individuals with interests in hearing research including advanced graduate students, post-doctoral researchers, and clinical investigators. The volumes are intended to introduce new investigators to important aspects of hearing science and to help established investigators to better understand the fundamental theories and data in fields of hearing that they may not normally follow closely. Each volume presents a particular topic comprehensively, and each serves as a synthetic overview and guide to the literature. As such, the chapters present neither exhaustive data reviews nor original research that has not yet appeared in pe- reviewed journals. The volumes focus on topics that have developed a solid data and conceptual foundation rather than on those for which a literature is only beg- ning to develop. New research areas will be covered on a timely basis in the series as they begin to mature.

Book Magnesium in the Central Nervous System

Download or read book Magnesium in the Central Nervous System written by Robert Vink and published by University of Adelaide Press. This book was released on 2011 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.

Book Scientific Foundations of Audiology

Download or read book Scientific Foundations of Audiology written by Anthony T. Cacace and published by Plural Publishing. This book was released on 2016-04-15 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: With advancements across various scientific and medical fields, professionals in audiology are in a unique position to integrate cutting-edge technology with real-world situations. Scientific Foundations of Audiology provides a strong basis and philosophical framework for understanding various domains of hearing science in the context of contemporary developments in genetics, gene expression, bioengineering, neuroimaging, neurochemistry, cochlear and mid-brain implants, associated speech processing and understanding, molecular biology, physics, modeling, medicine, and clinical practice. Key features of this text include: Highly technical information presented in a cohesive and understandable manner (i.e., concepts without complex equations)Discussion of integrating newly developed technology within the clinical practice of audiologyState-of-the-art contributions from a stellar array of international, world-class experts Scientific Foundations of Audiology is geared toward doctoral students in audiology, physics, and engineering; residents in otolaryngology, neurology, neurosurgery, and pediatrics; and those intermediaries between innovation and clinical reality.

Book Psychophysics  Physiology and Models of Hearing

Download or read book Psychophysics Physiology and Models of Hearing written by Torsten Dau and published by World Scientific. This book was released on 1999 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in auditory neuroscience are characterized by a close interaction between neurophysiological findings, psychophysical effects and integrative models that attempt to bridge the gap between neuroscience and psychophysics. This volume introduces the latest developments in this quickly evolving interdisciplinary area. Tutorials by leading international scientists as well as more focused contributions by active researchers providing an invaluable summary of our current knowledge of psychophysics and auditory physiology and the main lines of research in this field. The book will be of interest to anyone involved in hearing research, including neuroscientists, behavioral scientists, acousticians and biophysicists.

Book Molecular Mechanisms of Sensorineural Hearing Loss and Development of Inner Ear Therapeutics

Download or read book Molecular Mechanisms of Sensorineural Hearing Loss and Development of Inner Ear Therapeutics written by Srdjan M Vlajkovic and published by . This book was released on 2021-10-25 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: The sense of hearing is vulnerable to environmental challenges, such as exposure to noise. More than 1.5 billion people experience some decline in hearing ability during their lifetime, of whom at least 430 million will be affected by disabling hearing loss. If not identified and addressed in a timely way, hearing loss can severely reduce the quality of life at various stages. Some causes of hearing loss can be prevented, for example from occupational or leisure noise. The World Health Organization estimates that more than 1 billion young people put themselves at risk of permanent hearing loss by listening to loud music over long periods of time. Mitigating such risks through public health action is essential to reduce the impact of hearing loss in the community. The etiology of sensorineural hearing loss is complex and multifactorial, arising from congenital and acquired causes. This book highlights the diverse range of approaches to sensorineural hearing loss, from designing new animal models of age-related hearing loss, to the use of microRNAs as biomarkers of cochlear injury and drug repurposing for the therapy of agerelated and noise-induced hearing loss. Further investigation into the underlying molecular mechanisms of sensorineural hearing loss and the integration of the novel drug, cell, and gene therapy strategies into controlled clinical studies will permit significant advances in a field where there are currently many unmet needs.

Book Occupational Noise Exposure

Download or read book Occupational Noise Exposure written by Department of Health and Human Services and published by Createspace Independent Publishing Platform. This book was released on 2014-02-19 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the Occupational Safety and Health Act of 1970, Congress declared that its purpose was to assure, so far as possible, safe and healthful working conditions for every working man and woman and to preserve our human resources. In this Act, the National Institute for Occupational Safety and Health (NIOSH) is charged with recommending occupational safety and health standards and describing exposure concentrations that are safe for various periods of employment-including but not limited to concentrations at which no worker will suffer diminished health, functional capacity, or life expectancy as a result of his or her work experience. By means of criteria documents, NIOSH communicates these recommended standards to regulatory agencies (including the Occupational Safety and Health Administration [OSHA]) and to others in the occupational safety and health community. Criteria documents provide the scientific basis for new occupational safety and health standards. These documents generally contain a critical review of the scientific and technical information available on the prevalence of hazards, the existence of safety and health risks, and the adequacy of control methods. In addition to transmitting these documents to the Department of Labor, NIOSH also distributes them to health professionals in academic institutions, industry, organized labor, public interest groups, and other government agencies. In 1972, NIOSH published Criteria for a Recommended Standard: Occupational Exposure to Noise, which provided the basis for a recommended standard to reduce the risk of developing permanent hearing loss as a result of occupational noise exposure [NIOSH 1972]. NIOSH has now evaluated the latest scientific information and has revised some of its previous recommendations. The 1998 recommendations go beyond attempting to conserve hearing by focusing on preventing occupational noise-induced hearing loss (NIHL). This criteria document reevaluates and reaffirms the recommended exposure limit (REL) for occupational noise exposure established by the National Institute for Occupational Safety and Health (NIOSH) in 1972. The REL is 85 decibels, A-weighted, as an 8-hr time-weighted average (85 dBA as an 8-hr TWA). Exposures at or above this level are hazardous. By incorporating the 4000-Hz audiometric frequency into the definition of hearing impairment in the risk assessment, NIOSH has found an 8% excess risk of developing occupational noise-induced hearing loss (NIHL) during a 40-year lifetime exposure at the 85-dBA REL. NIOSH has also found that scientific evidence supports the use of a 3-dB exchange rate for the calculation of TWA exposures to noise. The recommendations in this document go beyond attempts to conserve hearing by focusing on prevention of occupational NIHL. For workers whose noise exposures equal or exceed 85 dBA, NIOSH recommends a hearing loss prevention program (HLPP) that includes exposure assessment, engineering and administrative controls, proper use of hearing protectors, audiometric evaluation, education and motivation, recordkeeping, and program audits and evaluations. Audiometric evaluation is an important component of an HLPP. To provide early identification of workers with increasing hearing loss, NIOSH has revised the criterion for significant threshold shift to an increase of 15 dB in the hearing threshold level (HTL) at 500, 1000, 2000, 3000, 4000, or 6000 Hz in either ear, as determined by two consecutive tests. To permit timely intervention and prevent further hearing losses in workers whose HTLs have increased because of occupational noise exposure, NIOSH no longer recommends age correction on individual audiograms.

Book Update On Hearing Loss

    Book Details:
  • Author : Fayez Bahmad
  • Publisher : BoD – Books on Demand
  • Release : 2015-12-02
  • ISBN : 9535121952
  • Pages : 208 pages

Download or read book Update On Hearing Loss written by Fayez Bahmad and published by BoD – Books on Demand. This book was released on 2015-12-02 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: Update on Hearing Loss encompasses both the theoretical background on the different forms of hearing loss and a detailed knowledge on state-of-the-art treatment for hearing loss, written for clinicians by specialists and researchers. Realizing the complexity of hearing loss has highlighted the importance of interdisciplinary research. Therefore, all the authors contributing to this book were chosen from many different specialties of medicine, including surgery, psychology, and neuroscience, and came from diverse areas of expertise, such as neurology, otolaryngology, psychiatry, and clinical and experimental audiology.

Book Auditory Trauma  Protection  and Repair

Download or read book Auditory Trauma Protection and Repair written by Jochen Schacht and published by Springer Science & Business Media. This book was released on 2008-02-10 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: The past decade has brought great advances in our understanding of the mechanisms underlying auditory pathologies. This volume presents recent developments in research and their potential translation to the clinical setting. It brings together the basic and clinical sciences very nicely in that while most chapters are written by basic scientists, each topic has a pretty direct clinical application or implication.

Book Hearing Health Care for Adults

    Book Details:
  • Author : National Academies of Sciences, Engineering, and Medicine
  • Publisher : National Academies Press
  • Release : 2016-10-06
  • ISBN : 0309439264
  • Pages : 325 pages

Download or read book Hearing Health Care for Adults written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-10-06 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: The loss of hearing - be it gradual or acute, mild or severe, present since birth or acquired in older age - can have significant effects on one's communication abilities, quality of life, social participation, and health. Despite this, many people with hearing loss do not seek or receive hearing health care. The reasons are numerous, complex, and often interconnected. For some, hearing health care is not affordable. For others, the appropriate services are difficult to access, or individuals do not know how or where to access them. Others may not want to deal with the stigma that they and society may associate with needing hearing health care and obtaining that care. Still others do not recognize they need hearing health care, as hearing loss is an invisible health condition that often worsens gradually over time. In the United States, an estimated 30 million individuals (12.7 percent of Americans ages 12 years or older) have hearing loss. Globally, hearing loss has been identified as the fifth leading cause of years lived with disability. Successful hearing health care enables individuals with hearing loss to have the freedom to communicate in their environments in ways that are culturally appropriate and that preserve their dignity and function. Hearing Health Care for Adults focuses on improving the accessibility and affordability of hearing health care for adults of all ages. This study examines the hearing health care system, with a focus on non-surgical technologies and services, and offers recommendations for improving access to, the affordability of, and the quality of hearing health care for adults of all ages.

Book Cochlear Hearing Loss

    Book Details:
  • Author : Brian C. J. Moore
  • Publisher : John Wiley & Sons
  • Release : 2007-09-27
  • ISBN : 9780470518182
  • Pages : 344 pages

Download or read book Cochlear Hearing Loss written by Brian C. J. Moore and published by John Wiley & Sons. This book was released on 2007-09-27 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the first edition was published in 1998, considerable advances have been made in the fields of pitch perception and speech perception. In addition, there have been major changes in the way that hearing aids work, and the features they offer. This book will provide an understanding of the changes in perception that take place when a person has cochlear hearing loss so the reader understands not only what does happen, but why it happens. It interrelates physiological and perceptual data and presents both this and basic concepts in an integrated manner. The goal is to convey an understanding of the perceptual changes associated with cochlear hearing loss, of the difficulties faced by the hearing-impaired person, and the limitations of current hearing aids.