Download or read book Microwave induced thermoacoustic imaging photoacoustic imaging written by Huan Qin and published by Frontiers Media SA. This book was released on 2023-02-13 with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Experimental Study of Microwave induced Thermoacoustic Imaging written by Ryan T. Jacobs and published by . This book was released on 2016 with total page 54 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Design of Compact Microwave induced Thermoacoustic Imaging Systems for Medical Screening Applications written by Hao Nan and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical imaging can create visual representations of the internal structure of a body for clinical analysis and therapeutic intervention. It has been successful in reducing the mortality rate of most diseases. However, the access to advanced imaging tools is limited to hospitals due to size, cost, and other constraints, which limits the screening frequency and widespread use, leading to missing some fast-growing and often fatal types of diseases. For example, the screening interval of mammography is limited by a desire to restrict the ionizing radiation due to X-ray, as well as secondary concerns of screening cost and the false positive rate. From a sampling point of view, a Nyquist screening is required to enable continuous monitoring and provide meaningful information for diagnosis. It needs significant innovations to scale the system into a compact dimension with low cost, to enable portable and even handheld operation without ionization radiation. The medical imaging community has long been in pursuit of such a suitable handheld imaging system which provides high contrast and resolution for point-of-care frequent screening and diagnostics. One such promising candidate is microwave-induced thermoacoustic (TA) imaging. As a multi-physics hybrid modality, TA imaging provides dielectric/conductivity contrast and ultrasound resolution at the same time. Ultrasound signals generated from thermal expansion differentials in soft tissue (the thermo-elastic response) are detected by a scanning single-element transducer or an ultrasonic array to form images. Combining microwave and acoustics provides the extra benefit of enabling a handheld and portable form factor, due to the integration potential of both modalities. This dissertation describes beamforming and coherent processing in TA imaging for improved signal generation and detection to enable handheld operations with low power and a small form factor. In TA beamforming, we increase the deposited radio frequency (RF) power to the target volume at depth and avoid excessive heating of the skin or surface by transmitting RF power from multiple locations instead of a single high-power element. With a phased array, we steer and control the RF focal point across the target region by tuning the phase of each channel. Spatial power combining can significantly improve TA signal generation at depth due to the coherent summation of E fields from excitation elements. In another direction, I perform coherent processing in TA imaging by exciting the target with the microwave of longer duration and much lower peak power compared to conventional pulse approaches. With matched-filter processing, we can reconstruct the target pulse response as well as achieving significant signal-to-noise ratio improvement by exploiting the amplitude and phase in the frequency domain. The coherent processing further reduces the requirements of the RF power source and enables fully solid-state implementation of TA imaging. The dissertation also presents a programmable integrated wideband RF transmitter for TA imaging based on the ST 55~nm BiCMOS technology. With the designed chip, the TA imaging system is scaled to a small form factor, while it can operate in both coherent mode and conventional pulse mode as well as simultaneous imaging and spectroscopy capability. By exploiting the different responses of tissues across microwave excitation frequency, TA spectroscopy provides another degree of freedom to enhance contrast, differentiate materials and help diagnosis. In addition, this dissertation demonstrates non-invasive temperature monitoring with TA imaging by exploiting temperature-dependent behavior, achieving degree accuracy in real time. The reconstruction algorithms in TA imaging are also discussed, including a proposed forward reconstruction algorithm which bypasses the ill-posed inverse problem by correlating the measured signals with pre-calculated point spread functions in an iterative manner.
Download or read book Photoacoustic Imaging and Spectroscopy written by Lihong V. Wang and published by CRC Press. This book was released on 2017-12-19 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: Photoacoustics promises to revolutionize medical imaging and may well make as dramatic a contribution to modern medicine as the discovery of the x-ray itself once did. Combining electromagnetic and ultrasonic waves synergistically, photoacoustics can provide deep speckle-free imaging with high electromagnetic contrast at high ultrasonic resolution and without any health risk. While photoacoustic imaging is probably the fastest growing biomedical imaging technology, this book is the first comprehensive volume in this emerging field covering both the physics and the remarkable noninvasive applications that are changing diagnostic medicine. Bringing together the leading pioneers in this field to write about their own work, Photoacoustic Imaging and Spectroscopy is the first to provide a full account of the latest research and developing applications in the area of biomedical photoacoustics. Photoacoustics can provide functional sensing of physiological parameters such as the oxygen saturation of hemoglobin. It can also provide high-contrast functional imaging of angiogenesis and hypermetabolism in tumors in vivo. Discussing these remarkable noninvasive applications and so much more, this reference is essential reading for all researchers in medical imaging and those clinicians working at the cutting-edge of modern biotechnology to develop diagnostic techniques that can save many lives and just as importantly do no harm.
Download or read book Photoacoustic and Thermoacoustic Tomography written by Geng Ku and published by . This book was released on 2006 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Photoacoustic tomography (PAT), as well as thermoacoustic tomography (TAT), utilize electromagnetic radiation in its visible, near infrared, microwave, and radiofrequency forms, respectively, to induce acoustic waves in biological tissues for imaging purposes. Combining the advantages of both the high image contrast that results from electromagnetic absorption and the high resolution of ultrasound imaging, these new imaging modalities could be the next successful imaging techniques in biomedical applications. Basic research on PAT and TAT, and the relevant physics, is presented in Chapter I. In Chapter II, we investigate the imaging mechanisms of TAT in terms of signal generation, propagation and detection. We present a theoretical analysis as well as simulations of such imaging characteristics as contrast and resolution, accompanied by experimental results from phantom and tissue samples. In Chapter III, we discuss the further application of TAT to the imaging of biological tissues. The microwave absorption difference in normal and cancerous breast tissues, as well as its influence on thermoacoustic wave generation and the resulting transducer response, is investigated over a wide range of electromagnetic frequencies and depths of tumor locations. In Chapter IV, we describe the mechanism of PAT and the algorithm used for image reconstruction. Because of the broad bandwidth of the laser-induced ultrasonic waves and the limited bandwidth of the single transducer, multiple ultrasonic transducers, each with a different central frequency, are employed for simultaneous detection. Chapter V further demonstrates PAT's ability to image vascular structures in biological tissue based on blood's strong light absorption capability. The photoacoustic images of rat brain tumors in this study clearly reveal the angiogenesis that is associated with tumors. In ChapterVI, we report on further developing PAT to image deeply embedded optical heterogeneity in biological tissues. The improved imaging ability is attributed to better penetration by NIR light, the use of the optical contrast agent ICG (indocyanine green) and a new detection scheme of a circular scanning configuration. Deep penetrating PAT, which is based on a tissue's intrinsic contrast using laser light of 532um [mu] green light and1.06 um [mu] near infrared light, is also presented.
Download or read book Handbook of Mathematical Methods in Imaging written by Otmar Scherzer and published by Springer Science & Business Media. This book was released on 2010-11-23 with total page 1626 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Mathematical Methods in Imaging provides a comprehensive treatment of the mathematical techniques used in imaging science. The material is grouped into two central themes, namely, Inverse Problems (Algorithmic Reconstruction) and Signal and Image Processing. Each section within the themes covers applications (modeling), mathematics, numerical methods (using a case example) and open questions. Written by experts in the area, the presentation is mathematically rigorous. The entries are cross-referenced for easy navigation through connected topics. Available in both print and electronic forms, the handbook is enhanced by more than 150 illustrations and an extended bibliography. It will benefit students, scientists and researchers in applied mathematics. Engineers and computer scientists working in imaging will also find this handbook useful.
Download or read book Scanning Microwave Induced Acoustic Tomography written by and published by . This book was released on 2001 with total page 39 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the previous report in 2002, we have published five peer-reviewed journal articles and delivered 12 invited talks. For the invited plenary talk given at UK, all travel related expenses were covered by the conference host. The combination of ultrasound and microwave has provided us a unique opportunity for early-cancer imaging with high resolution and high contrast. A good imaging modality should have both high contrast and high spatial resolution. Our imaging technology combines synergistically radiofrequency waves and ultrasonic waves, where the former provides high contrast and the latter provides high spatial resolution. Only non-ionizing radiation is used. No painful breast compression is' required. In addition, our images are free of speckle artifacts, which are prevalent in conventional ultrasound images. Our ultimate goal is to detect early breast cancer.
Download or read book Multi wave Electromagnetic Acoustic Sensing and Imaging written by Fei Gao and published by Springer. This book was released on 2017-02-01 with total page 169 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis covers a broad range of interdisciplinary topics concerning electromagnetic-acoustic (EM-Acoustic) sensing and imaging, mainly addressing three aspects: fundamental physics, critical biomedical applications, and sensing/imaging system design. From the fundamental physics perspective, it introduces several highly interesting EM-Acoustic sensing and imaging methods, which can potentially provide higher sensitivity, multi-contrast capability, and better imaging performance with less distortion. From the biomedical applications perspective, the thesis introduces useful techniques specifically designed to address selected challenging biomedical applications, delivering rich contrast, higher sensitivity and finer spatial resolution. Both phantom and ex vivo experiments are presented, and in vivo validations are progressing towards real clinical application scenarios. From the sensing and imaging system design perspective, the book proposes several promising sensing/imaging prototypes. Further, it offers concrete suggestions that could bring these systems closer to becoming “real” products and commercialization, such as replacing costly lasers with portable laser diodes, or integrating transmitting and data recording on a single board.
Download or read book Biomedical Optics written by Lihong V. Wang and published by John Wiley & Sons. This book was released on 2012-09-26 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: This entry-level textbook, covering the area of tissue optics, is based on the lecture notes for a graduate course (Bio-optical Imaging) that has been taught six times by the authors at Texas A&M University. After the fundamentals of photon transport in biological tissues are established, various optical imaging techniques for biological tissues are covered. The imaging modalities include ballistic imaging, quasi-ballistic imaging (optical coherence tomography), diffusion imaging, and ultrasound-aided hybrid imaging. The basic physics and engineering of each imaging technique are emphasized. A solutions manual is available for instructors; to obtain a copy please email the editorial department at [email protected].
Download or read book Molecular Imaging written by Ralph Weissleder and published by PMPH-USA. This book was released on 2010 with total page 1384 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of molecular imaging of living subjects have evolved considerably and have seen spectacular advances in chemistry, engineering and biomedical applications. This textbook was designed to fill the need for an authoritative source for this multi-disciplinary field. We have been fortunate to recruit over 80 leading authors contributing 75 individual chapters. Given the multidisciplinary nature of the field, the book is broken into six different sections: "Molecular Imaging technologies", "Chemistry", "Molecular Imaging in Cell and Molecular Biology", "Applications of Molecular Imaging", "Molecular Imaging in Drug Evaluation" with the final section comprised of chapters on computation, bioinformatics and modeling. The organization of this large amount of information is logical and strives to avoid redundancies among chapters. It encourages the use of figures to illustrate concepts and to provide numerous molecular imaging examples.
Download or read book Photoacoustic Tomography PAT written by Xueding Wang and published by MDPI. This book was released on 2021-02-17 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt: Photoacoustic (or optoacoustic) imaging, including photoacoustic tomography (PAT) and photoacoustic microscopy (PAM), is an emerging imaging modality with great clinical potential. PAI’s deep tissue penetration and fine spatial resolution also hold great promise for visualizing physiology and pathology at the molecular level. PAI combines optical contrast with ultrasonic resolution, and is capable of imaging at depths of up to 7 cm with a real-time scalable spatial resolution of 10 to 500 µm. PAI has demonstrated applications in brain imaging and cancer imaging, such as breast cancer, prostate cancer, ovarian cancer etc. This Special Issue focuses on the novel technological developments and pre-clinical and clinical biomedical applications of PAI. Topics include but are not limited to: brain imaging; cancer imaging; image reconstruction; quantitative imaging; light source and delivery for PAI; photoacoustic detectors; nanoparticles designed for PAI; photoacoustic molecular imaging; photoacoustic spectroscopy.
Download or read book Transpathology written by Mei Tian and published by Elsevier. This book was released on 2024-06-25 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transpathology: Molecular Imaging-Based Pathology is a multidisciplinary reference on molecular imaging and pathology. The book is intended for professionals in the fields of molecular imaging, nuclear medicine, radiology, and pathology as well as students and clinical residents. The book describes the importance of non-invasive diagnosis-based precision medicine and presents a detailed description of current transpathological approaches in different aspects essential for the future development of precision medicine. It's molecular imaging approach to experimental research and clinical practice will drive the field forward and improve research outcomes. - Introduces a new concept of molecular imaging-guided precise biopsy - Links in vivo and ex vivo information at various scales by using multi-modality imaging technologies - Integrates future technologies for the non-invasive cross-validation of underlying mechanisms
Download or read book Photoacoustic Tomography written by Minghua Xu and published by CRC PressI Llc. This book was released on 2014-09-30 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Photoenergy and Thin Film Materials written by Xiao-Yu Yang and published by John Wiley & Sons. This book was released on 2019-03-19 with total page 650 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the latest research & developments and future trends in photoenergy and thin film materials—two important areas that have the potential to spearhead the future of the industry. Photoenergy materials are expected to be a next generation class of materials to provide secure, safe, sustainable and affordable energy. Photoenergy devices are known to convert the sunlight into electricity. These types of devices are simple in design with a major advantage as they are stand-alone systems able to provide megawatts of power. They have been applied as a power source for solar home systems, remote buildings, water pumping, megawatt scale power plants, satellites, communications, and space vehicles. With such a list of enormous applications, the demand for photoenergy devices is growing every year. On the other hand, thin films coating, which can be defined as the barriers of surface science, the fields of materials science and applied physics are progressing as a unified discipline of scientific industry. A thin film can be termed as a very fine, or thin layer of material coated on a particular surface, that can be in the range of a nanometer in thickness to several micrometers in size. Thin films are applied in numerous areas ranging from protection purposes to electronic semiconductor devices. The 16 chapters in this volume, all written by subject matter experts, demonstrate the claim that both photoenergy and thin film materials have the potential to be the future of industry.
Download or read book Bioinformatics and Biomedical Engineering New Advances written by James Chou and published by CRC Press. This book was released on 2015-10-29 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 9th International Conference on Bioinformatics and Biomedical Engineering (iCBBE 2015) was held on September 18-20, 2015, Shanghai, China. This proceedings volume assembles papers from various professionals engaged in the fields of Biomedical Engineering, Bioinformatics and Computational Biology. The conference had special sessio
Download or read book Advances in Molecular Biophotonics written by Yong Deng and published by Walter de Gruyter GmbH & Co KG. This book was released on 2017-04-24 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Being the most active field in modern physics, Optical Physics has developed many new branches and interdisciplinary fields overlapping with various classical disciplines. This series summarizes the advancements of optical physics in the past twenty years in the following fields: High Field Laser Physics, Precision Laser Spectroscopy, Nonlinear Optics, Nanophotonics, Quantum Optics, Ultrafast Optics, Condensed Matter Optics, and Molecular Biophotonics.
Download or read book Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation written by Gerard Socie and published by Academic Press. This book was released on 2018-11-22 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation: Models in Discovery and Translation, Second Edition once again provides clinical and scientific researchers with a deep understanding of the current research in this field and the implications for translational practice. By providing an overview of the immune biology of HSCT, an explanation of immune rejection, and detail on antigens and their role in HSCT success, this book embraces biologists and clinicians who need a broad view of the deeply complex processes involved. It then moves on to discuss the immunobiology mechanisms that influence graft-versus-host disease (GVHD), graft-versus-leukemia effect, and transplantation success. Using illustrative figures, highlighting key issues, describing recent successes, and discussing unanswered questions, this book sums up the current state of HSCT to enhance the prospects for the future. The second edition is fully revised and includes new chapters on microbiome, metabolism, kinase targets, micro-RNA and mRNA regulatory mechanisms, signaling pathways in GVHD, innate lymphoid system development, recovery and function in GVHD, genetically engineered T-cell therapies, immune system engagers for GVHD and graft-versus-tumor, and hematopoietic cell transplant for tolerance induction in solid organ grafts. - Brings together perspectives from leading laboratories and clinical research groups to highlight advances from bench to the bedside - Guides readers through the caveats that must be considered when drawing conclusions from studies with animal models before correlating to clinical allogeneic hematopoietic stem cell transplantation (HSCT) scenarios - Categorizes the published advances in various aspects of immune biology of allogeneic HSCT to illustrate opportunities for clinical applications
