Download or read book Microbiology and Aging written by Steven L. Percival and published by Springer Science & Business Media. This book was released on 2008-12-11 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited volume contains a collection of reviews that highlight the significance of, and the crucial role, that microorganisms play in the human life cycle and considers the microbiology of the host in different regions of the body during the aging process.
Download or read book Aging of Organisms written by H.D. Osiewacz and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological aging as the time-depending general decline of biological systems associated with a progressively increasing mortality risk is a general phenomenom of great significance. The underlying processes are very complex and depending on genetic and environment factors. These factors encode or affect a network of interconnected cellular pathways. In no system this network has been deciphered in greater detail. However, the strategy of studying various biological systems has let to the identification of pathways and specific modules and makes it obvious that aging is the result of different overlapping mechanisms and pathways. Some of these appear to be conserved ("public") among species, others are specific or "private" and only of significance in one or a few organisms. This volume in the series on "Biology of aging and its modulation" specifically focuses on organismic aging. The book covers research on organisms from lower to higher complexity representing examples from very diverse taxa like photosynthetic plants, fungi, sponges, nematodes, flies, birds and mammals. Such a broad treatise of this complex topic provides a comprehensive "flavor" about the current issues dealt with in this rapidly growing scientific discipline.
Download or read book Aging of the Organs and Systems written by Richard Aspinall and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last 40 years, the study of the biological basis of aging has progressed tremendously, and it has now become an independent and respectable field of study and research. This volume on "Aging of Organs and Systems", is an attempt to bring understanding to both the aging process and the disease processes of old age. Bringing together contributions from an international team of authors, it will be of interest to graduates and postgraduates in the fields of medicine and nursing, researchers of different aspects of biogerontology and those in the pharmaceutical, cosmeceutical, nutriceutical and health-care industry.
Download or read book Gut Microbiota in Aging and Chronic Diseases written by Francesco Marotta and published by Springer Nature. This book was released on 2023-01-01 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited volume studies gut microbiota peculiarities in elderly, in senescence-related and environmental-related alterations of gut microbiota in chronic diseases. Aging, as a physiological process mediated through several regulatory pathways and transcription factors, is generally speaking associated to a relentless functional decline and increasing risk of chronic diseases. Growing data on gut microbiota quali-quantitative changes in aging gut, and the opportunity to study by advanced NGS and metabolomic technologies, now offers novel horizons to link such changes to disease risks and to theoretically the weapons for gut microbiota intervention as an effective therapeutic tool. Chapters are divided into clear sections, starting with the aging perspective, then moving from chronic diseases to neurodegenerative diseases and cancer. The final parts focusses on interventions. Contributors are well-reputed and dedicated scientists in clinics and experimental medicine from 4 different continents who have provided their contribution keeping the polar star on aging as a guide while investigating their gut microbiota in occurrence and progression of disease together with proposed preventing, monitoring and therapeutic interventions. In the wide offer of books on gut microbiota, this age-thematic volume will be a valuable source of updated information for a wide group of readership including gerontologists, geriatricians, medical specialists of several fields, PhDs, basic scientists and public/private research entities focused on potential intervention in and through gut ecosystem. This book will stimulate a large number of basic scientists and clinicians to review their once organ (or cellular line)-specific knowledge and widen either their pathophysiological mechanisms understanding while providing novel ways to prevent, monitor and treat diseases from eyes to bones.
Download or read book Handbook of the Biology of Aging written by Nicolas Musi and published by Academic Press. This book was released on 2015-08-20 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of the Biology of Aging, Eighth Edition, provides readers with an update on the rapid progress in the research of aging. It is a comprehensive synthesis and review of the latest and most important advances and themes in modern biogerontology, and focuses on the trend of ‘big data’ approaches in the biological sciences, presenting new strategies to analyze, interpret, and understand the enormous amounts of information being generated through DNA sequencing, transcriptomic, proteomic, and the metabolomics methodologies applied to aging related problems. The book includes discussions on longevity pathways and interventions that modulate aging, innovative new tools that facilitate systems-level approaches to aging research, the mTOR pathway and its importance in age-related phenotypes, new strategies to pharmacologically modulate the mTOR pathway to delay aging, the importance of sirtuins and the hypoxic response in aging, and how various pathways interact within the context of aging as a complex genetic trait, amongst others. Covers the key areas in biological gerontology research in one volume, with an 80% update from the previous edition Edited by Matt Kaeberlein and George Martin, highly respected voices and researchers within the biology of aging discipline Assists basic researchers in keeping abreast of research and clinical findings outside their subdiscipline Presents information that will help medical, behavioral, and social gerontologists in understanding what basic scientists and clinicians are discovering New chapters on genetics, evolutionary biology, bone aging, and epigenetic control Provides a close examination of the diverse research being conducted today in the study of the biology of aging, detailing recent breakthroughs and potential new directions
Download or read book Aging Research in Yeast written by Michael Breitenbach and published by Springer. This book was released on 2014-01-28 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume includes contributions by the leading experts in the field of yeast aging. Budding yeast (Saccharomyces cerevisiae) and other fungal organisms provide models for aging research that are relevant to organismic aging and to the aging processes occurring in the human body. Replicative aging, in which only the mother cell ages while the daughter cell resets the clock to zero is a model for the aging of stem cell populations in humans, while chronological aging (measured by survival in stationary phase) is a model for the aging processes in postmitotic cells (for instance, neurons of the brain). Most mechanisms of aging are studied in yeast. Among them, this book discusses: mitochondrial theories of aging, emphasizing oxidative stress and retrograde responses; the role of autophagy and mitophagy; the relationship of apoptosis to aging processes; the role of asymmetric segregation of damage in replicative aging; the role of replication stress; and the role of the cytoskeleton in aging. Modern methods of yeast genetics and genomics are described that can be used to search for aging-specific functions in a genome-wide unbiased fashion. The similarities in the pathology of senescence (studied in yeast) and of cancer cells, including genome instability, are examined.
Download or read book Modulating Aging and Longevity written by S.I. Rattan and published by Springer. This book was released on 2010-12-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: After decades of systematic collection of data describing age-related changes in organisms, organs, tissues, cells and macromolecules, biogerontologists are now in a position to construct general principles of ageing and explore various possibilities of intervention using rational approaches. While not giving serious consideration to the claims made by charlatans, it cannot be ignored that several researchers are making genuine attempts to test and develop various means of intervention for the prevention and treatment of age-related diseases, for regaining the functional abilities and for prolonging the lifespan of experimental organisms. This book provides the most up-to-date information and a critical evaluation of a variety of approaches being tried for modulating aging and longevity, including dietary supplementation with antioxidants, vitamins and hormones, genetic engineering, life-style alterations, and hormesis through mild stress. The goal of research on ageing is not to increase human longevity regardless of the consequences, but to increase active longevity free from disability and functional dependence.
Download or read book Aging at the Molecular Level written by Thomas von Zglinicki and published by Springer. This book was released on 2012-03-14 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last 40 years, the study of the biological basis of aging has progressed tremendously, and it has now become an independent and respectable field of study and research. The essential cause of aging is molecular damage that slowly overwhelms cellular and organismic defense, repair and maintenance systems. In recent years, a wealth of highly sophisticated research has transformed this idea from a credible hypothesis not only to a major theory, but essentially to accepted knowledge. Aging at the Molecular Level examines the key elements in this transformation. Bringing together contributions from an international team of authors, this volume will be of interest to graduates and postgraduates in the fields of medicine and nursing, researchers of different aspects of biogerontology and those in the pharmaceutical, cosmeceutical, nutraceutical and health-care industry.
Download or read book Biological Aging written by Trygve O. Tollefsbol and published by Humana Press. This book was released on 2013-08-09 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of Biological Aging: Methods and Protocols expands upon the previous edition with current, detailed, useful and promising methods currently available to study aging. With new chapters on protocols that detail aging cell culture as well as many more contemporary approaches such as nuclear transfer, microarray and proteomics technologies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Biological Aging: Methods and Protocols, Second Edition details the most recent breakthroughs in technology that have served to advance the study of aging.
Download or read book The Gerontological Imagination written by Kenneth F. Ferraro and published by Oxford University Press. This book was released on 2018 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: The power of the gerontological imagination -- Causality -- Life course analysis -- Multifaceted change -- Heterogeneity -- Accumulation process -- Ageism -- The gerontological imagination at work in scientific communities
Download or read book Aging and Human Longevity written by Marie-Francoise Schulz-Aellen and published by Birkhäuser. This book was released on 1997 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The proportion of elderly people continues to increase in the western world-nearly a quarter of the population will be over 65 years by the year 2050. Since aging is accompanied by an increase in diseases and by a deterioration in well-being, finding solutions to these social, medical and psychological problems is necessarily a major goal for society. Scientists and medical practitioners are therefore faced with the urgent task of increasing basic knowledge of the biological processes that cause aging. More resources must be put into this research in order to achieve better understanding of the cellular mechanisms that underlie the differences in life span between species and to answer the difficult questions of why some individuals age more quickly than others, and why some develop liver problems, some have heart problems, and others brain problems. The results of such a wide program of research will provide important information about the causes of many life-threatening and/ or debilitating diseases of old age; it will help find ways to prevent some of the ailments that result from aging, and it may well lead to discoveries enabling the prolongation of human life.
Download or read book Handbook of Aging and the Social Sciences written by Linda George and published by Academic Press. This book was released on 2010-11-26 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Aging and the Social Sciences, Seventh Edition, provides extensive reviews and critical evaluations of research on the social aspects of aging. It also makes available major references and identifies high-priority topics for future research. The book is organized into four parts. Part 1 reviews developments in the field of age and the life course (ALC) studies and presents guidelines on conducting cohort analysis. Part 2 covers the demographic aspects of aging; longevity trends; disability and aging; and stratification and inequality research. Part 3 includes chapters that examine socioeconomic position and racial/ethnic disparities in health at older ages; the role of social factors in the distribution, antecedents, and consequences of depression; and aspects of private wealth transfers and the changing nature of family gift-giving. Part 4 deals with pension reform in Europe; the political activities of older Americans; the future of retirement security; and gender differences in old age. The Handbook is intended for researchers, professional practitioners, and students in the field of aging. It can also serve as a basic reference tool for scholars, professionals, and others who are not presently engaged in research and practice directly focused on aging and the aged. Contains all the main areas of social science gerontological research in one volume Begins with a section on theory and methods Edited by one of the fathers of gerontology (Binstock) and contributors represent top scholars in gerontology
Download or read book Aging written by Paulo J. Oliveira and published by Elsevier. This book was released on 2022-09-15 with total page 820 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aging: From Fundamental Biology to Societal Impact examines the interconnection of the cellular and molecular basis of aging and societal-based challenges and innovative interventions. Sections take a societal-based angle on aging, describing several flagship initiatives for healthy living and active aging in different regions, cover the biology of aging which includes the hallmarks of aging, explain the pathophysiology of aging, describing different comorbidities associated with aging and possible interventions to decrease the impact of aging, and envision future and innovative measures to tackle aging-related morbidities. Contributions from an interdisciplinary panel of experts cover such topics as the biology of aging to physical activity, nutrition, psychology, pharmacology, health care, social care and urban planning. Provides a cross-disciplinary approach to aging at both the biological and societal level Highlights frontline scientific knowledge in the biology of aging and its translation into societal interventions Offers insights on the value of aging research and its future impact from a fundamental and translation point-of-view
Download or read book Aging Technology and Health written by Richard Pak and published by Academic Press. This book was released on 2018-03-15 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aging, Health and Technology takes a problem-centered approach to examine how older adults use technology for health. It examines the many ways in which technology is being used by older adults, focusing on challenges, solutions and perspectives of the older user. Using aging-health technology as a lens, the book examines issues of technology adoption, basic human factors, cognitive aging, mental health, aging and usability, privacy, trust and automation. Each chapter takes a case study approach to summarize lessons learned from unique examples that can be applied to similar projects, while also providing general information about older adults and technology. Discusses human factors design challenges specific to older adults Covers the wide range of health-related uses for technology—from fitness to leading a more engaged life Utilizes a case study approach for practical application Envisions what the future will hold for technology and older adults Employs a roster of interdisciplinary contributors
Download or read book Textbook of Aging Skin written by Miranda A. Farage and published by Springer Science & Business Media. This book was released on 2009-12-02 with total page 1255 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive ‘Major Reference Book’ compiles all current and latest information on aging skin in a two-volume set. Highly structured with a reader-friendly format, it covers a wide range of areas such as basic sciences, the different diseases and conditions which occur with aging (from malignant to non-malignant), the latest techniques and methods being used such as bioengineering methods and biometrics as well as toxicological and safety considerations for the elderly population. It also illustrates the global consumers’ sociological and psychological implications, ethnicity and gender differences and includes marketing considerations for this elderly group. This unique and comprehensive guide will become the main reference textbook on this topic.
Download or read book HANDBOOK OF CELL BIOLOGY OF AGING written by Vincent J. Cristofalo and published by Springer. This book was released on 1985-12-30 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Model Systems in Aging written by Thomas Nyström and published by Springer. This book was released on 2010-10-22 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aging is the progressive decline in biological functions over time. This decline targets macromolecules, cells, tissues and, as a consequence, whole organisms. Despite considerable progress in the development of testable hypothesis concerning aging in an evolutionary context, a unifying theory of the molecular/physiological mechanistic causes of aging has not been reached. In fact, is it not clear to what extent aging is a programmed or stochastic process. This book takes the reader from unicellular bacterial deterioration via senescence in yeast and worms to aging in rodents and humans, allowing a comparative view on similarities and differences in different genetic model systems. The different model systems are scrutinized in the light of contemporary aging hypothesis, such as the free radical and genomic instability theories.
