Download or read book Microbicides for Prevention of HIV Infection written by Jeremy Nuttall and published by Springer. This book was released on 2014-09-06 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the most promising new approaches for the prevention of HIV transmission, particularly for developing countries, involves topical, self-administered products known as microbicides. The development of microbicides is a long and complicated process, and this volume provides an overview of all the critical areas, from the selection of appropriate candidate molecules and their formulation, preclinical and clinical testing for safety and efficacy, strategies for product registration and finally, issues associated with product launch, distribution and access. The book will prove valuable to both those working in the field and all others who are interested in learning more about this product class, which has the potential to significantly impact the future of this devastating epidemic.

Download or read book Drug Delivery and Development of Anti HIV Microbicides written by Jose das Neves and published by CRC Press. This book was released on 2014-10-16 with total page 679 pages. Available in PDF, EPUB and Kindle. Book excerpt: The worldwide impact of HIV/AIDS is well recognized. This book provides for the first time a thorough and critical overview of current aspects, recent developments, and trends in the formulation and drug delivery concerning anti-HIV microbicides by leading scientists in the field. Additionally, pertinent regulatory aspects and socioeconomical issue

Download or read book The Development of Microbicides written by Christopher J. Elias and published by . This book was released on 1993 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book HIV Prevention written by Kenneth H. Mayer and published by Academic Press. This book was released on 2009-03-13 with total page 692 pages. Available in PDF, EPUB and Kindle. Book excerpt: HIV/AIDS continues to be the pandemic of our times and there has not been a comprehensive medically based AIDS prevention book published in the last 5 years. It is estimated that 36 to 45 million people including 2-3 million children already are infected worldwide and an additional 4-7 million more are infected each year. There are about 6,000 new infections daily and about 12 million AIDS orphans. People receiving AIDS treatments feel well and have no detectable viral load, but still can infect others. And even when a vaccine is found, it will take many years before it can be administered across the developing world. - Discusses all aspects of AIDS prevention, from epidemiology, molecular immunology and virology to the principles of broad-based public health prevention interventions - Special focus on the array of interventions that have been proven effective through rigorous study - Identifies new trends in HIV/AID epidemiology and their impact on creating and implementing prevention interventions - Incorporates virology, biology, infectious diseases, vaccinology, microbicides and research methodologies into AIDS prevention

Download or read book Microbicides for HIV prevention written by Joint United Nations Programme on HIV/AIDS. and published by . This book was released on 1998 with total page 7 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book No Time to Lose written by Institute of Medicine and published by National Academies Press. This book was released on 2001-03-02 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: The United States has spent two productive decades implementing a variety of prevention programs. While these efforts have slowed the rate of infection, challenges remain. The United States must refocus its efforts to contain the spread of HIV and AIDS in a way that would prevent as many new HIV infections as possible. No Time to Lose presents the Institute of Medicine's framework for a national prevention strategy.

Download or read book Biomedical Advances in HIV Prevention written by Lisa A. Eaton and published by Springer Science & Business Media. This book was released on 2013-10-08 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomedical Advances in HIV Prevention: Social and Behavioral Perspectives Lisa A. Eaton and Seth C. Kalichman, editors Three decades into the epidemic, a great deal is known about HIV and its transmission, more people are living with the disease, and the virus is no longer seen as a death sentence. But new people continue to be infected with HIV each year, making prevention strategies that are medically effective and behaviorally engaging as urgent a priority as ever. Biomedical Advances in HIV Prevention: Social and Behavioral Perspectives assembles the latest improvements, barriers to implementation, and possibilities for--and challenges to--future progress. Innovations such as pre-exposure prophylaxis (antiretroviral regimens for the high-risk uninfected) and treatment as prevention (early use of ART to reduce infectiousness of new patients) are examined, as are current findings on ongoing prevention and treatment concerns. Contributors illuminate the complex realities entailing adherence, pointing out technological, behavioral, and cultural roadblocks as well as opportunities to significantly reduce infection rates. Detailed up-to-the-minute coverage includes: Prevention services for persons living with HIV Adherence to HIV treatment as prevention and pre-exposure prophylaxis Advocating for rectal microbicides and safe lubricants Mental health and substance use in the scale-up of HIV prevention Risk compensation in response to HIV prevention Implementing biomedical HIV prevention advances: reports from South Africa, Uganda, Australia, Thailand, United States, Ecuador, and Peru Researchers, practitioners, and policy makers working in the fields of HIV/AIDS and public health will look toward Biomedical Advances in HIV Prevention: Social and Behavioral Perspectives as both a means for developing and assessing current programs and a blueprint for the next generation of prevention efforts.

Download or read book Bioethical Challenges in New Hiv Prevention Technologies written by Calvin Gwandure and published by Xlibris Corporation. This book was released on 2018-05-23 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ruth Gwandure earned her master of science degree in medicine (bioethics and law) from the University of the Witwatersrand, South Africa. Her research and consulting fields include bioethics, health law, environmental bioethics, research ethics, HIV and AIDS, ethics and law, clinical ethics, and HIV counselling and testing in schools. Calvin Gwandure has a PhD in psychology. He graduated from Nelson Mandela University, South Africa. His research and consulting fields include HIV and AIDS prevention, new HIV prevention technologies, HIV risk behavior, and group behavior. Clinical trials on HIV and AIDS prevention face challenges associated with infection of participants with HIV and sexually transmitted infections. Participants also experience adverse events associated with voluntary medical male circumcision and the use of microbicides and vaccines in clinical trials. The results obtained from clinical trials investigating the efficacy of microbicides and vaccines in preventing HIV infection are disappointing, but there is hope that one day a breakthrough could be made. Clinical trials on voluntary medical male circumcision and preexposure prophylaxis have shown positive results that warranted approval by the US Food and Drug Administration (FDA) and the World Health Organization (WHO). The major challenge experienced in new HIV prevention clinical trials that are underway and in approved interventions that are being scaled up apparently relates to HIV incidence that threatens the social value and scientific validity of the interventions. Paradoxically, the clinical trials and scale-up interventions have become the new sources of HIV infection although the hypothesized benefit to be realized in the end is conceptualized as outweighing the current risks involved.

Download or read book HIV written by Frederic Bushman and published by Cold Spring Harbor Perspective. This book was released on 2012 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The basic biology of the HIV virus provides a model for a more general understanding of retroviruses, and the worldwide epidemic of AIDS makes research into the disease process and potential therapies among the most critical in biomedical science. This book explores work on the molecular biology of HIV, host-virus interactions, host immune responses, HIV transmission, and more.

Download or read book Trends in Basic and Therapeutic Options in HIV Infection written by Bartholomew Ibeh and published by BoD – Books on Demand. This book was released on 2015-09-02 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: The past decade has seen several changes in HIV prevention, transmission and therapeutic interventions to end the scourge. This book is a collection of expert assays on various aspects of HIV prevention, bioresource deployment, microbicides, host antiviral proteins, antiviral drug responses and novel treatment strategies for which there is evident need for scientific focus and review of the current trend. A visible objective of the book is to provide a wider readership of scientist, clinicians, social workers/HIV caregivers, immunologist, postgraduate students, trainers and vaccine developers an informative and multidisciplinary approach to HIV treatment and intervention strategy by presenting current trends in the development of therapeutic options and its attendant challenges. Practical and informative, the book provides state-of-the-art information on dynamics of HIV distribution, transmission, therapeutic measures and functional cure.

Download or read book Disease Control Priorities Third Edition Volume 6 written by King K. Holmes and published by World Bank Publications. This book was released on 2017-11-06 with total page 1027 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

Download or read book Women Initiated Solutions for HIV Prevention WISH Study written by Sonia M. Kandathil and published by . This book was released on 2010 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: With women comprising nearly 50% of HIV/AIDS infections globally, the development of new woman-initiated HIV prevention methods has become a public health imperative. To date, the female condom and the diaphragm are the only woman-initiated prevention methods available on the consumer market. Recent research has focused on two HIV/AIDS prevention technologies undergoing clinical trials: microbicides and tenofovir (PrEP). Both are being touted as female-initiated HIV/AIDS prevention technologies that women can use covertly, without a partner's knowledge, to improve their odds in protecting themselves against HIV. Use of these new technologies will not only depend on their effectiveness, but on women's willingness to use these products. This cross-sectional study used an integrative conceptual model that included both intrapersonal and interpersonal constructs to explore factors associated with women's intentions to use. Three hundred and forty-eight high-risk women in Toronto, Canada completed self-administered questionnaires (SAQs). Results were remarkably consistent across relationship types and prevention methods examined in the study, with 60% of the women intending to use microbicides and tenofovir. Women who perceived themselves to be at greater risk for STIs, had greater microbicide self-efficacy, and more positive perceptions of microbicides were more likely to intend to use microbicides. Women with

Download or read book Microbicides 2000 written by and published by . This book was released on 2001 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book HIV AIDS Global Frontiers in Prevention Intervention written by Cynthia Pope and published by Routledge. This book was released on 2014-06-11 with total page 778 pages. Available in PDF, EPUB and Kindle. Book excerpt: HIV/AIDS: Global Frontiers in Prevention/Intervention provides a comprehensive overview of the global HIV/AIDS epidemic. The unique anthology addresses cutting-edge issues in HIV/AIDS research, policymaking, and advocacy. Key features include: · Nine original essays from leading scholars in public health, epidemiology, and social and behavioral sciences · Comprehensive information for individuals with varying degrees of knowledge, particularly regarding methodological and theoretical perspectives · A look into the future progression of HIV transmission and scholarly research HIV/AIDS: Global Frontiers in Prevention/Intervention is will serve as a precious resource as a textbook and reference for the university classroom, libraries, and researchers

Download or read book Women and Health written by Marlene B. Goldman and published by Academic Press. This book was released on 2012-12-31 with total page 1616 pages. Available in PDF, EPUB and Kindle. Book excerpt: Women and Health is a comprehensive reference that addresses health issues affecting women of all ages — from adolescence through maturity. It goes far beyond other books on this topic, which concentrate only on reproductive health, and has a truly international perspective. It covers key issues ranging from osteoporosis to breast cancer and other cancers, domestic violence, sexually transmitted diseases, occupational hazards, eating disorders, heart disease and other chronic illnesses, substance abuse, and societal and behavioral influences on health. In this second edition of Women and Health, chapters thoughtfully explore the current state of women's health and health care, including the influences of sex and gender on the occurrence of a wide variety of diseases and conditions. All chapters have been extensively updated and emphasize the epidemiology of the condition — the etiology, occurrence, primary and secondary prevention (screening), risk factors, surveillance, changing trends over time, and critical analysis of the diagnostic and treatment options and controversies. Treatment sections in each chapter have been expanded to create a stronger dialogue between epidemiologists and women's health practitioners. - Saves researchers and clinicians time in quickly accessing the very latest details on a broad range of women's health issues, as opposed to searching through thousands of journal articles - Provides a common language for epidemiologists, public health practitioners, and women's health specialists to discuss the behavioral, cultural, and biological determinants of women's health - Researchers and medical specialists will learn how the gender-specific risks and features of one organ system's diseases affect the health of other organ systems - For example: Hormone replacement therapy used to treat imbalance within the endocrine system is also being used to prevent and treat cardiovascular disease; Drugs developed for type 2 diabetes are now being used in chemoprevention - Orients the non-gerontologist about the importance of considering the entire life cycle of women within research designs and treatment plans - Professors teaching courses in women's health will use slides and additional materials to structure lectures/courses; students will use slides as a unique resource to study for exams

Download or read book Microbicides for HIV Prevention written by Kimberley Lufkin and published by . This book was released on 2013 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis examines how advocates and funders in the U.S. global health and international development community conceptualize vaginal microbicides, or products such as gels, films, rings and sponges that women could apply vaginally for HIV prevention. An interdisciplinary approach was employed, combining anthropological and feminist theoretical frameworks and research methods, such as semistructured interviews, participant observation and a focus group discussion. This thesis finds that U.S. microbicide advocates and supporters see these products as a tool to maintain prevailing gender identities that assign men sexual decision-making authority and prestige. At the same time, U.S. microbicide advocates resist gender identities that define men as powerful and women as passive. In these situations, they view vaginal microbicides as a tool that women can use to wrestle sexual decision-making powers from men. From science and technology studies, this thesis employs the concept of non-human agency to argue that microbicide advocates assign to these products a noteworthy amount of power and capacity. Also from science and technology studies, the theory of situated knowledge helps analyze claims made by microbicide advocates, particularly the political implications of claiming to speak from the position of African women. Politics and power are also central themes when examining how vaginal microbicides are entangled with broader U.S. health and development objectives in Africa, and this thesis argues that the rhetoric circulating in the U.S. microbicide advocacy community echoes historical paradigms about health and sexuality in Africa. This thesis also demonstrates that vaginal microbicides do a significant amount of political work, as U.S. microbicide advocates and supporters endow these vaginal products with a distinct level of power to achieve broader U.S. international development goals, such as improving gender relations and empowering women in Africa.

Download or read book Models of Protection Against HIV SIV written by Gianfranco Pancino and published by Academic Press. This book was released on 2011-12-02 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: A successful vaccine for the prevention and/or immunotherapy against HIV/AIDS is one of the prominent challenges of the 21st century. To date, all human vaccine trials against this virus/disease have resulted in failure, or at best have shown very low efficacy. The scientific community dealing with HIV/AIDS has unanimously proposed a focus on basic science, with the intention of identifying correlates of protection that can serve as guides in developing and evaluating vaccine preparation. However, Nature seems to have already found several ways of dealing with infections by HIV and related primate lentiviruses, either by resisting infection or, once infected, avoiding immune damage and immunodeficiency. Models of Protection Against HIV/SIV will allow for an in-depth reflection on the perspectives for vaccine and therapy research derived from important recent studies. It will be authored by some of the most well known specialists in the field of HIV resistance/protection: including F. Barré-Sinoussi (2008 Nobel Prize for Medicine winner), B. Walker, S. Rowland-Jones, A. Telenti, M. Lederman and F. Plummer. This book is structured in a unique way, looking at three models of resistance/protection separately and then comparing the models against one another to provide its readership with a detailed examination of the research that is most predominant in the search for a vaccine. This structure presents the information in an easy-to-understand format and gives the book a cross-discipline appeal -- an important reference for those in the scientific community, medical care, public health and academia alike. Provides extensive descriptions and comparisons on the different models of protection agains HIV/AIDS Comprehensive writing and illustrations Contributors are among the most eminent specialists in the field