Download or read book Mg2 and Excitable Membranes written by Piergiorgio Strata and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 153 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents the most recent research findings on the key role played by Mg2+ in the regulation of ion channels in excitable tissue. Contributions describe the multiple actions exerted by Mg2+ on the different types on ion channels controlling nerve and cardiac cell activity. Recent developments in the detection of single ion channel activity provide important insights into the mechanisms of action of Mg2+ at the channel level.
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Calcium Entry Channels in Non Excitable Cells written by Juliusz Ashot Kozak and published by CRC Press. This book was released on 2017-07-14 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: Calcium Entry Channels in Non-Excitable Cells focuses on methods of investigating the structure and function of non-voltage gated calcium channels. Each chapter presents important discoveries in calcium entry pathways, specifically dealing with the molecular identification of store-operated calcium channels which were reviewed by earlier volumes in the Methods in Signal Transduction series. Crystallographic and pharmacological approaches to the study of calcium channels of epithelial cells are also discussed. Calcium ion is a messenger in most cell types. Whereas voltage gated calcium channels have been studied extensively, the non-voltage gated calcium entry channel genes have only been identified relatively recently. The book will fill this important niche.
Download or read book Magnesium in the Central Nervous System written by Robert Vink and published by University of Adelaide Press. This book was released on 2011 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.
Download or read book From Molecules to Networks written by Ruth Heidelberger and published by Academic Press. This book was released on 2009-01-27 with total page 654 pages. Available in PDF, EPUB and Kindle. Book excerpt: An understanding of the nervous system at virtually any level of analysis requires an understanding of its basic building block, the neuron. From Molecules to Networks provides the solid foundation of the morphologic, biochemical, and biophysical properties of nerve cells. All chapters have been thoroughly revised for this second edition to reflect the significant advances of the past 5 years. The new edition expands on the network aspects of cellular neurobiology by adding a new chapter, Information Processing in Neural Networks, and on the relation of cell biological processes to various neurological diseases. The new concluding chapter illustrates how the great strides in understanding the biochemical and biophysical properties of nerve cells have led to fundamental insights into important aspects of neurodegenerative disease. - Written and edited by leading experts in the field, the second edition completely and comprehensively updates all chapters of this unique textbook - Discusses emerging new understanding of non-classical molecules that affect neuronal signaling - Full colour, professional graphics throughout - Includes two new chapters: Information Processing in Neural Networks - describes the principles of operation of neural networks and the key circuit motifs that are common to many networks in the nervous system. Molecular and Cellular Mechanisms of Neurodegenerative Disease - introduces the progress made in the last 20 years in elucidating the cellular and molecular mechanisms underlying brain disorders, including Amyotrophic Lateral Sclerosis (ALS), Parkinson disease, and Alzheimer's disease
Download or read book Medical Surgical Nursing E Book written by Donna D. Ignatavicius and published by Elsevier Health Sciences. This book was released on 2013-12-27 with total page 1905 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using a uniquely collaborative and reader-friendly approach, expert authors Donna D. Ignatavicius and M. Linda Workman cover all the latest trends, evidence-based treatment guidelines, and additional updated information needed for safe clinical practice in medical-surgical nursing. This seventh edition features an expanded emphasis on patient safety and NCLEX® Examination preparation, new ties to the QSEN priorities for patient safety, and a greater alignment with the language and focus of clinical practice. A new chapter on evidence-based practice and a wealth of effective online learning tools help solidify your mastery of medical-surgical nursing. UNIQUE! Collaborative approach presents all medical, surgical, nursing, and other interventions through the lens of the nursing process. Reader-friendly, direct writing style makes this one of the most readable medical-surgical nursing textbooks available. UNIQUE! Cutting-edge focus on the latest trends in nursing practice and nursing education prepares you for both today and tomorrow’s nursing practice. UNIQUE! Integrated tools for NCLEX preparation get you ready for your licensure examination. Chapter-opening Learning Outcomes are linked to Self-Assessment Questions for the NCLEX Examination on the Evolve website. Unique chapter-ending Get Ready for the NCLEX Examination! sections include Key Points organized by NCLEX Client Needs Categories. UNIQUE! Focus on nursing concepts helps bridge the gap between the concepts learned in Nursing Fundamentals, and disorders content learned in the medical-surgical nursing course. UNIQUE! Emphasis on clinical decision-making teaches you to apply concepts to true-to-life clinical situations. UNIQUE! Concentration on the core body of knowledge for the RN level of medical-surgical nursing practice focuses your attention on "need-to-know" content to pass the NCLEX Examination and practice safely as a beginning nurse. Rich array of effective learning aids includes: Best Practice for Patient Safety & Quality Care Best Practice for Emergency Care Patient and Family Education: Preparing for Self-Management Nursing Focus on the Older Adult Home Care Assessment Focused Assessment Common Examples of Drug Therapy Evidence-Based Practice Concept Maps Laboratory Profiles Assessment Using Gordon’s Functional Health Patterns
Download or read book Introduction to Epilepsy written by Gonzalo Alarcón and published by Cambridge University Press. This book was released on 2012-04-26 with total page 641 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covers all aspects of epilepsy, from basic mechanisms to diagnosis and management, as well as legal and social considerations.
Download or read book Cardiac Electrophysiology Methods and Models written by Daniel C. Sigg and published by Springer Science & Business Media. This book was released on 2010-09-11 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiovascular disease is the major cause of mortality and morbidity in the Western Hemisphere. While significant progress has been made in treating a major sub-category of cardiac disease, arrhythmias, significant unmet needs remain. In particular, every day, thousands of patients die because of arrhythmias in the US alone, and atrial fibrillation is the most common arrhythmia affecting millions of patients in the US alone at a given time. Therefore, there is a public need to continue to develop new and better therapies for arrhythmias. Accordingly, an ever increasing number of biomedical, pharmaceutical, and medical personnel is interested in studying various aspects of arrhythmias at a basic, translational, and applied level, both in industry (ie Biotech, Pharmaceutical and device), and in academia. Not only has our overall understanding of molecular bases of disease dramatically increased, but so has the number of available and emerging molecular, pharmacological or device treatment based therapies. This practical, state-of-the art handbook will summarize and review key research methods and protocols, their advantages and pitfalls, with a focus on practical implementation, and collaborative cross-functional research. The volume will include visual and easy-to-use graphics, bulleted summaries, boxed summary paragraphs, links to reference websites, equipment manufacturers where appropriate, photographs of typical experimental setups and so forth, to keep this book very focused on practical methods and implementation, and yet, provide enough theory that the principles are clearly understood and can be easily applied.
Download or read book Biochemistry written by David E. Metzler and published by Elsevier. This book was released on 2001-04-25 with total page 968 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most comprehensive textbook/reference ever to cover the chemical basis of life, the "Green Bible of Biochemistry" has been a well-respected contribution to the field for more than twenty years. The complex structures that make up cells are described in detail, along with the forces that hold them together, and the chemical reactions that allow for recognition, signaling and movement. There is ample information on the human body, its genome, and the action of muscles, eyes, and the brain. The complete set deals with the natural world, treating the metabolism of bacteria, toxins, antibiotics, specialized compounds made by plants, photosynthesis, luminescence of fireflies, among many other topics.* The most comprehensive biochemistry text reference available on the market* Organized into two volumes, comprising 32 chapters and containing the latest research in the field* Biological content is emphasized: for example, macromolecular structures and enzyme action are discussed
Download or read book Central Nervous System Trauma written by S. Tsuyoshi Ohnishi and published by CRC Press. This book was released on 1995-07-27 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: Central nervous system trauma, which encompasses stroke, subarachnoid hemorrhage, head injury, and spinal cord injury, is a leading cause of death in developed countries. In the search for underlying mechanisms, membrane involvement has been the common link. This fourth volume in the Membrane-Linked Diseases series is therefore dedicated to research on CNS trauma. Focusing on the mechanism of membrane damage, Central Nervous System Trauma: Research Techniques presents a variety of experimental techniques to study the mechanism of CNS trauma. Animal and tissue culture models provide the bulk of the research findings in this area. Possible pharmacological interventions are analyzed. This volume offers numerous illustrative examples, including full color figures. This book serves as a valuable resource for students and researchers, assisting in the comprehension of current trends in CNS trauma and helping to stimulate the discovery of new research areas.
Download or read book Cellular and Molecular Neurophysiology written by Constance Hammond and published by Academic Press. This book was released on 2014-12-30 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cellular and Molecular Neurophysiology, Fourth Edition, is the only up-to-date textbook on the market that focuses on the molecular and cellular physiology of neurons and synapses. Hypothesis-driven rather than a dry presentation of the facts, the book promotes a real understanding of the function of nerve cells that is useful for practicing neurophysiologists and students in a graduate-level course on the topic alike. This new edition explains the molecular properties and functions of excitable cells in detail and teaches students how to construct and conduct intelligent research experiments. The content is firmly based on numerous experiments performed by top experts in the field This book will be a useful resource for neurophysiologists, neurobiologists, neurologists, and students taking graduate-level courses on neurophysiology. - 70% new or updated material in full color throughout, with more than 350 carefully selected and constructed illustrations - Fifteen appendices describing neurobiological techniques are interspersed in the text
Download or read book Medical Surgical Nursing written by Donna D. Ignatavicius and published by Elsevier Health Sciences. This book was released on 2015-02-09 with total page 1735 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using a unique collaborative care approach to adult health nursing, Medical-Surgical Nursing: Patient-Centered Collaborative Care, 8th Edition covers the essential knowledge you need to succeed at the RN level of practice. Easy-to-read content includes evidence-based treatment guidelines, an enhanced focus on QSEN competencies, and an emphasis on developing clinical judgment skills. This edition continues the book's trendsetting tradition with increased LGBTQ content and a new Care of Transgender Patients chapter. Written by nursing education experts Donna Ignatavicius and M. Linda Workman, this bestselling text also features NCLEX® Exam-style challenge questions to prepare you for success on the NCLEX Exam. Cutting-edge coverage of the latest trends in nursing practice and nursing education prepares you not just for today's nursing practice but also for tomorrow's. UNIQUE! Collaborative care approach organizes all medical, surgical, nursing, and other interventions within the framework of the nursing process, mirroring the nurse's role in the coordination/management of care in the real world of medical-surgical nursing. UNIQUE! A focus on nursing concepts relates concepts learned in Nursing Fundamentals with the disorders you will study in Medical-Surgical Nursing. Easy to read, direct-address writing style makes this one of the most readable medical-surgical nursing textbooks available. UNIQUE! A focus on QSEN emphasizes patient safety and evidence-based practice with Nursing Safety Priority boxes including Drug Alerts, Critical Rescues, and Action Alerts. UNIQUE! Emphasis on clinical judgment teaches you to develop skills in clinical reasoning and clinical decision-making when applying concepts to clinical situations, with Clinical Judgment Challenge questions throughout the chapters. An emphasis on prioritization stresses the most important patient problems and nursing interventions, with patient problems presented in a single prioritized list of nursing diagnoses and collaborative problems. UNIQUE! NCLEX preparation tools include chapter-opening Learning Outcomes and chapter-ending Get Ready for the NCLEX Examination! sections organized by NCLEX® Client Needs Categories, plus NCLEX Examination Challenge questions, with an answer key in the back of the book and on the Evolve companion website. Practical learning aids include NCLEX Examination Challenges, Clinical Judgment Challenges, Best Practice for Patient Safety & Quality Care charts, common examples of drug therapy, concept maps, laboratory profiles, and more. A clear alignment with the language of clinical practice reflects the real world of nursing practice with NANDA diagnostic labels where they make sense, and non-NANDA diagnostic labels when these are more common descriptions of patient problems. Student Resources on an Evolve companion website help you prepare for class, clinicals, or lab with video and audio clips, animations, case studies, a concept map creator, NCLEX exam-style review questions, and more. UNIQUE! Concentration on essential knowledge for the RN level of medical-surgical nursing practice focuses your attention on need-to-know content to pass the NCLEX Examination and practice safety as a beginning nurse. NEW! Enhanced focus on QSEN (Quality and Safety Education for Nurses) competencies includes new icons identifying QSEN competency material and new Quality Improvement boxes describing projects that made a dramatic difference in patient outcomes. UPDATED learning features include an expanded emphasis on developing clinical judgment skills; on prioritization, delegation, and supervision skills; on long-term care issues; and on preparation for the NCLEX® Examination and consistency with the 2013 NCLEX-RN® Test Plan. NEW! UNIQUE! Care of Transgender Patients chapter discusses the unique health care needs and issues specific to the transgender community. Improved delineation of NANDA-I nursing diagnoses clearly differentiate NANDA diagnoses from collaborative problems. NEW photos and drawings show patient care skills as well as the latest in nursing education and practice.
Download or read book Smith s Anesthesia for Infants and Children E Book written by Peter J. Davis and published by Elsevier Health Sciences. This book was released on 2016-10-15 with total page 1829 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now thoroughly up to date with new chapters, Smith’s Anesthesia for Infants and Children, 9th Edition, by Drs. Peter Davis and Franklyn Cladis, covers the information you need to provide effective perioperative care for any type of pediatric surgery. Leading experts in pediatric anesthesia bring you up to date with every aspect of both basic science and clinical practice, helping you incorporate the latest clinical guidelines and innovations in your practice. Quick-reference appendices: drug dosages, growth curves, normal values for pulmonary function tests, and a listing of common and uncommon syndromes. Outstanding visual guidance in full color throughout the book. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. More than 100 video demonstrations, including new regional anesthesia videos, echocardiograms of congenital heart lesions, anatomic dissections of various congenital heart specimens with audio explanations, various pediatric surgical operative procedures, airway management, and much more. Table of Contents has been reorganized and new chapters added on statistics, sedation, pediatric obesity, and cardiac critical care pediatrics. A new chapter on regional anesthesia for pediatrics, including video and ultrasound demonstrations online. A new chapter on dermatology, specifically for the anesthesiologist, with more than 100 photos. A new chapter on medical missions to third-world countries, including what you should know before you go. A new Questions chapter provides opportunities for self-assessment. New coverage includes cardiac anesthesia for congenital heart disease, anesthesia outside the operating room, and a new neonatology primer for the pediatric anesthesiologist.
Download or read book Ciliary and Flagellar Membranes written by R.A. Bloodgood and published by Springer Science & Business Media. This book was released on 2013-03-07 with total page 443 pages. Available in PDF, EPUB and Kindle. Book excerpt: A volume entirely devoted to the nonaxonemal structures and functions of eukaryotic cilia and flagella. The fifteen chapters cover a wide spectrum of organisms (from protozoa and algae to birds and mammals) and an equally wide spectrum of topics (from sexual interactions in the algae to the binding
Download or read book Smith s Anesthesia for Infants and Children E Book written by Etsuro K. Motoyama and published by Elsevier Health Sciences. This book was released on 2010-12-09 with total page 1447 pages. Available in PDF, EPUB and Kindle. Book excerpt: Smith’s Anesthesia for Infants and Children, 8th Edition, edited by Drs. Peter J. Davis, Franklyn P. Cladis, and Etsuro K. Motoyama, delivers all the state-of-the-art guidance you need to provide optimal perioperative care for any type of pediatric surgery. Now in full color throughout, it also features online access to an image and video library, including ultrasound-guided pediatric regional blocks, review-style questions, plus the complete fully-searchable text at expertconsult.com. Get expert guidance from leading experts covering both basic science and clinical practice for every aspect of pediatric anesthesia. Incorporate the latest clinical guidelines and innovations in your practice. Find key facts fast with quick-reference appendices: drug dosages, growth curves, normal values for pulmonary function tests, and a listing of common and uncommon syndromes. Access the complete contents and illustrations online at expertconsult.com – fully searchable! Watch online video demonstrations of ultrasound-guided and conventional pediatric regional blocks, airway management, cardiac anesthesia, single-lung ventilation, neonatal surgery, and fetal surgery. Gain new insight into today’s hottest topics, including sleep-disordered breathing, cuffed endotracheal tubes, premedication, emergence agitation, postoperative vomiting, and new airway devices. Stay current with new chapters on ICU management, conjoined twins, and basic neonatal physiology, plus new coverage of pharmacology and monitoring techniques. Get outstanding visual guidance with full-color illustrations throughout the book.
Download or read book Heart Physiology and Pathophysiology written by Yoshihisa Kurachi and published by Elsevier. This book was released on 2000-10-09 with total page 1286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heart Physiology and Pathophysiology, 4E, provides the foundation for the scientific understanding of heart function and dysfunction, and bridges the gap between basic cardiovascular science and clinical cardiology. This comprehensive text covers all the important aspects of the heart and vascular system. The most important and relevant disorders are presented, with emphasis on the mechanisms involved. The first three editions of this book developed a reputation as the leading reference in cardiovascular science for researchers and academic cardiologists. This recent edition has been updated, expanded, and includes a number of new contributors. It has also been remodeled to expand its usage as a text reference for cardiology residents, practicing cardiologists, and graduate students.Key Features* The most comprehensive book available on this topic* Clear, concise, and complete coverage of all important aspects of cardiovascular physiology/pathophysiology* Completely updated version of the foremost reference on cardiovascular science, including new information on pathophysiology and electrophysiology* Useful tool in bridging the gap between basic science, pathophysiology, and clinical cardiology
Download or read book Electrophysiology Measurements for Studying Neural Interfaces written by Mohammad M. Aria and published by Academic Press. This book was released on 2020-05-15 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Electrophysiology Measurements for Studying Neural Interfaces helps readers to choose a proper cell line and set-up for studying different bio-electronic interfaces before delving into the electrophysiology techniques available. Therefore, this book details the materials and devices needed for different types of neural stimulation such as photoelectrical and photothermal stimulations. Also, modern techniques like optical electrophysiology and calcium imaging in this book provides readers with more available approaches to monitor neural activities in addition to whole-cell patch-clamp technology. - Details steps of an electrophysiology project from start to finish for graduate students employing the technique in their research - Includes sample electrophysiological studies with multiple cell lines (PC12, N2a, NG108, SHSY, and embryonic stem cell lines) to facilitate research - Features data analysis of electrophysiology results from various relevant experiments and cell culture tips
