Download or read book Fmoc Solid Phase Peptide Synthesis written by W. Chan and published by OUP Oxford. This book was released on 1999-12-16 with total page 371 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the publication of Atherton and Sheppard's volume, the technique of Fmoc solid-phase peptide synthesis has matured considerably and is now the standard approach for the routine production of peptides. The focus of this new volume is much broader, and covers the essential procedures.
Download or read book The Chemistry of Amides written by Jacob Zabicky and published by . This book was released on 1970 with total page 927 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Principles of Peptide Synthesis written by Miklos Bodanszky and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Peptide Synthesis is a very successful book by one of the pioneers of contemporary bioorganic synthesis. Its first edition proved a valuable source that is kept close to the work bench for frequent consulting. Any researcher planning the formation of the peptide bond, be it for the synthesis of a peptide chain or a cyclic peptide, benefits from the author's experience. The concise and critical treatment of the steps involved: protection, activation and bond formation require careful planning to avoid racemization and undesired side reactions. The second edition has been completely revised and updated. New procedures that have been developed since the first edition was published and that did not fit into the original are added in a separate chapter. This separation of old and new make it possible to assess new ideas and discern novel trends.
Download or read book Isocyanide based Multicomponent Reactions written by Jonathan G. Rudick and published by Frontiers Media SA. This book was released on 2020-02-20 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Download or read book The World of Peptides written by Theodor Wieland and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: Almost two centuries ago proteins were recognized as the primary materials (proteios = primary) oflife, but the significance and wide role of peptides (from pepsis = digestion) in practically all life pro cesses has only become apparent in the last few decades. Biologi cally active peptides are now being discovered at rapid intervals in the brain and in other organs including the heart, in the skin of amphibians and many other tissues. Peptides and peptide-like compounds are found among toxins and antibiotics. It is unlikely that this process, an almost explosive broadening of the field, will come to a sudden halt. By now it is obvious that Nature has used the combination of a small to moderate number of amino acids to generate a great variety of agonists with specific and often highly sophisticated functions. Thus, peptide chemistry must be regarded as a discipline in its own right, a major branch of biochemistry, fairly separate from the chemistry of proteins. Because of the important role played by synthesis both in the study and in the practical preparation of peptides, their area can be considered as belonging to bio-organic chemistry as well. The already overwhelming and still increasing body of know ledge renders an account of the history of peptide chemistry more and more difficult. It appears therefore timely to look back, to take stock and to recall the important stages in the development of a new discipline.
Download or read book Total Synthesis of Natural Products written by Jie Jack Li and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'Total Synthesis of Natural Products' is written and edited by some of today's leaders in organic chemistry. Eleven chapters cover a range of natural products, from steroids to alkaloids. Each chapter contains an introduction to the natural product in question, descriptions of its biological and pharmacological properties and outlines of total synthesis procedures already carried out. Particular emphasis is placed on novel methodologies developed by the respective authors and their research groups. This text is ideal for graduate and advanced undergraduate students, as well as organic chemists in academia and industry.
Download or read book Synthesis of Biaryls written by Ivica Cepanec and published by Elsevier. This book was released on 2010-07-07 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organic chemistry is one of the most rapidly growing sciences. There is a wide variety of applications of organic compounds, for instance, pharmaceutically active substances, agrochemicals, optoelectronics, etc. Within this group there are hundereds and thousands of new compounds synthesized or isolated from natural sources. Such important organic chemistry developments are accompanied by the profound break-through of new reactions, increasingly efficient methodologies, reagents and catalysts. The chemistry of biaryls is one of the most interesting fields in organic chemistry, this book looks at these reactions both new and old. Synthesis of Biaryls presents the description of a given method for the synthesis of biaryls: short introduction, reaction mechanism, application, representative synthetic procedures, conclusion and literature references. This book will be of interest to organic chemists in industry and academia. - A topic of growing importance in organic synthesis - The FIRST book to cover all reactions for the synthesis of biaryls, including the most recent - The book provides detailed applications of each method described
Download or read book Arene Chemistry written by Jacques Mortier and published by John Wiley & Sons. This book was released on 2015-11-30 with total page 992 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organized to enable students and synthetic chemists to understand and expand on aromatic reactions covered in foundation courses, the book offers a thorough and accessible mechanistic explanation of aromatic reactions involving arene compounds. • Surveys methods used for preparing arene compounds and their transformations • Connects reactivity and methodology with mechanism • Helps readers apply aromatic reactions in a practical context by designing syntheses • Provides essential information about techniques used to determine reaction mechanisms
Download or read book Handbook of Metathesis 3 Volume Set written by Robert H. Grubbs and published by John Wiley & Sons. This book was released on 2015-05-26 with total page 1639 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering the complete breadth of the olefin metathesis reaction. The second edition of the ultimate reference in this field is completely updated and features more than 80% new content, with the focus on new developments in the field, especially in industrial applications. No other book covers the topic in such a comprehensive manner and in such high quality, and this new edition retains the three-volume format: Catalyst Development, Applications in Organic Synthesis and Polymer Synthesis. Edited by a Nobel laureate in the field, and with a list of contributors that reads like a "Who's-Who" of metathesis, this is an indispensable one-stop reference for organic, polymer and industrial chemists, as well as chemists working with organometallics. Individual volumes also available separately to purchase Volume 1: Catalyst Development - http://www.wiley.com/WileyCDA/WileyTitle/productCd-3527339485.html Volume 2: Applications in Organic Synthesis - http://www.wiley.com/WileyCDA/WileyTitle/productCd-3527339493.html Volume 3: Polymer Synthesis - http://www.wiley.com/WileyCDA/WileyTitle/productCd-3527339507.html
Download or read book Acids and Bases written by Brian G. Cox and published by OUP Oxford. This book was released on 2013-01-31 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acids and bases are ubiquitous in chemistry. Our understanding of them, however, is dominated by their behaviour in water. Transfer to non-aqueous solvents leads to profound changes in acid-base strengths and to the rates and equilibria of many processes: for example, synthetic reactions involving acids, bases and nucleophiles; isolation of pharmaceutical actives through salt formation; formation of zwitter- ions in amino acids; and chromatographic separation of substrates. This book seeks to enhance our understanding of acids and bases by reviewing and analysing their behaviour in non-aqueous solvents. The behaviour is related where possible to that in water, but correlations and contrasts between solvents are also presented. Fundamental background material is provided in the initial chapters: quantitative aspects of acid-base equilibria, including definitions and relationships between solution pH and species distribution; the influence of molecular structure on acid strengths; and acidity in aqueous solution. Solvent properties are reviewed, along with the magnitude of the interaction energies of solvent molecules with (especially) ions; the ability of solvents to participate in hydrogen bonding and to accept or donate electron pairs is seen to be crucial. Experimental methods for determining dissociation constants are described in detail. In the remaining chapters, dissociation constants of a wide range of acids in three distinct classes of solvents are discussed: protic solvents, such as alcohols, which are strong hydrogen-bond donors; basic, polar aprotic solvents, such as dimethylformamide; and low-basicity and low polarity solvents, such as acetonitrile and tetrahydrofuran. Dissociation constants of individual acids vary over more than 20 orders of magnitude among the solvents, and there is a strong differentiation between the response of neutral and charged acids to solvent change. Ion-pairing and hydrogen-bonding equilibria, such as between phenol and phenoxide ions, play an increasingly important role as the solvent polarity decreases, and their influence on acid-base equilibria and salt formation is described.
Download or read book Frontiers in Chemical Engineering written by National Research Council and published by National Academies Press. This book was released on 1988-02-01 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the next 10 to 15 years, chemical engineers have the potential to affect every aspect of American life and promote the scientific and industrial leadership of the United States. Frontiers in Chemical Engineering explores the opportunities available and gives a blueprint for turning a multitude of promising visions into realities. It also examines the likely changes in how chemical engineers will be educated and take their place in the profession, and presents new research opportunities.
Download or read book Peptide Analysis Protocols written by Ben M. Dunn and published by Humana. This book was released on 2013-12-06 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the technology base for the preparation of increasingly c- plex peptides has improved, the methods for their purification and ana- sis have also been improved and supplemented. Peptide science routinely utilizes tools and techniques that are common to organic chemistry, p- tein chemistry, biophysical chemistry, enzymology, pharmacology, and molecular biology. A fundamental understanding of each of these areas is essential for interpreting all of the data that a peptide scientist may see. The purpose of Peptide Analysis Protocols is to provide the novice with sufficient practical information necessary to begin developing useful analysis and separation skills. Understanding and developing these skills will ultimately yield a scientist with broadened knowledge and good problem-solving abilities. Although numerous books that address d- ferent specialties, such as HPLC, FAB-MS, CE, and NMR, have been written, until now no single volume has reviewed all of these techniques with a focus on "getting started" in separation and analysis of peptides. This volume will also provide those who already possess practical knowledge of the more advanced aspects of peptide science with detailed applications for each of these protocols. Because the chapters have been written by researchers active in each of the fields that they discuss, a great deal of information on and insight into solution of real problems that they have encountered is presented. Examplary results are clearly demonstrated and discussed. For more advanced investi- tions, supplementary experiments are often suggested.
Download or read book Polyurethanes written by Mark F. Sonnenschein and published by John Wiley & Sons. This book was released on 2020-12-29 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, cohesively written by an expert author with supreme breadth and depth of perspective on polyurethanes, provides a comprehensive overview of all aspects of the science and technology on one of the most commonly produced plastics. Covers the applications, manufacture, and markets for polyurethanes, and discusses analytical methods, reaction mechanisms, morphology, and synthetic routes Provides an up-to-date view of the current markets and trend analysis based on patent activity and updates chapters to include new research Includes two new chapters on PU recycling and PU hybrids, covering the opportunities and challenges in both
Download or read book Nanostructures for Novel Therapy written by Denisa Ficai and published by Elsevier. This book was released on 2017-02-25 with total page 908 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanostructures for Novel Therapy: Synthesis, Characterization and Applications focuses on the fabrication and characterization of therapeutic nanostructures, in particular, synthesis, design, and in vitro and in vivo therapeutic evaluation. The chapters provide a cogent overview of recent therapeutic applications of nanostructured materials that includes applications of nanostructured materials for wound healing in plastic surgery and stem cell therapy. The book explores the promise for more effective therapy through the use of nanostructured materials, while also assessing the challenges their use might pose from both an economic and medicinal point of view. This innovative look at how nanostructured materials are used in therapeutics will be of great benefit to researchers, providing a greater understanding of the different ways nanomaterials could improve medical treatment, along with a discussion of the obstacles that need to be overcome in order to guarantee widespread availability. - Outlines how the characteristics of nanostructures made from different materials gives particular properties that can be successfully used in therapeutics - Compares the properties of different nanostructures, allowing medicinal chemists and engineers to select which are most appropriate for their needs - Highlights new uses of nanostructures within the therapeutic field, enabling the discovery of new, more effective drugs
Download or read book Supramolecular Chemistry in the 3rd Millennium written by Catherine E. Housecroft and published by MDPI. This book was released on 2021-08-18 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Special Issue is one of the first for the new MDPI flagship journal Chemistry (ISSN 2624-8549) which has a broad remit for publishing original research in all areas of chemistry. The theme of this issue is Supramolecular Chemistry in the 3rd Millennium and I am sure that this topic will attract many exciting contributions. We chose this topic because it encompasses the unity of contemporary pluridisciplinary science, in which organic, inorganic, physical and theoretical chemists work together with molecular biologists and physicists to develop a systems-level understanding of molecular interactions. The description of supramolecular chemistry as 'chemistry beyond the molecule' (Jean-Marie Lehn, Nobel Lecture and Gautam R. Desiraju, Nature, 2001, 412, 397) addresses the wide variety of weak, non-covalent interactions that are the basis for the assembly of supramolecular architectures, molecular receptors and molecular recognition, programed molecular systems, dynamic combinatorial libraries, coordination networks and functional supramolecular materials. We welcome submissions from all disciplines involved in this exciting and evolving area of science.
Download or read book ACS Style Guide written by Anne M. Coghill and published by American Chemical Society. This book was released on 2006 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the time since the second edition of The ACS Style Guide was published, the rapid growth of electronic communication has dramatically changed the scientific, technical, and medical (STM) publication world. This dynamic mode of dissemination is enabling scientists, engineers, and medicalpractitioners all over the world to obtain and transmit information quickly and easily. An essential constant in this changing environment is the requirement that information remain accurate, clear, unambiguous, and ethically sound.This extensive revision of The ACS Style Guide thoroughly examines electronic tools now available to assist STM writers in preparing manuscripts and communicating with publishers. Valuable updates include discussions of markup languages, citation of electronic sources, online submission ofmanuscripts, and preparation of figures, tables, and structures. In keeping current with the changing environment, this edition also contains references to many resources on the internet.With this wealth of new information, The ACS Style Guide's Third Edition continues its long tradition of providing invaluable insight on ethics in scientific communication, the editorial process, copyright, conventions in chemistry, grammar, punctuation, spelling, and writing style for any STMauthor, reviewer, or editor. The Third Edition is the definitive source for all information needed to write, review, submit, and edit scholarly and scientific manuscripts.
Download or read book Superelectrophiles and Their Chemistry written by George A. Olah and published by John Wiley & Sons. This book was released on 2008-01-03 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Superelectrophiles and Their Chemistry contains, for the first-time, a discussion of the basics of this emerging field of organic chemistry, alongside tools to help the reader apply the chemistry. Specific tools include an evaluation of the ways to increase the strength of electrophiles, the classification of superelectrophiles, the solvation issues, a review of methods for studying superelectrophilicity, with details of the superelectrophiles that have been identified and studied. Additional information includes substituent effects in activation of superelectrophiles, and solvation in chemical reactions, as well as an insightful look into future applications.
