Download or read book Metabolic Responses of Dairy Cows with Fatty Liver to Treatment with Glucagon written by Arnold Ray Hippen and published by . This book was released on 1997 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: To test the hypothesis that glucagon will decrease the severity of fatty liver and prevent ketosis, glucagon was continuously infused via intravenous jugular catheters into dairy cattle in several physiological states. In preliminary dosage response studies, glucagon was infused into eight spayed Holstein heifers, four midlactation Holstein cows, and four early-lactation Brown Swiss cows in cross-over design trials at dosages of 20 mg/d or less for 48 h. Plasma glucose concentrations were increased by glucagon in a dose-dependent manner. Plasma nonesterified fatty acid and ketone body concentrations were not increased by glucagon at 5 mg/d or less, were increased in heifers at 10 mg/d, and increased in cows at 20 mg/d compared with preinfusion concentrations. Glucagon at 10 mg/d was the largest dosage tested in lactating cows that did not elicit a lipolytic or ketogenic response. Glucagon at 10 mg/d or vehicle then was infused for 14 d during a protocol to induce ketosis in 20 early-lactation Holstein cows already having fatty livers.
Download or read book Metabolic Responses of Lactating Dairy Cows to Exogenous Glucagon written by Gerd Bobe and published by . This book was released on 2002 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fatty liver is a major metabolic disorder of dairy cows in early lactation that compromises their health status and reproductive performance and in clinical cases decreases milk production and feed intake. Fatty liver can be treated with 14-d continuous, intravenous infusions of 10 mg/d of glucagon. The objective of the current study was to test whether treatment of fatty liver with 14-d subcutaneous injections of glucagon at 7.5 or 15 mg/d, which is more practical than infusion, would cause similar metabolic responses and improve health status and reproductive performance of dairy cows in early lactation. In the main study, multiparous Holstein cows (n=32) were grouped on the basis of their liver triacylglycerol concentration at d 8 postpartum into "Normal" (n=8; triacylglycerol 1% liver wet wt) and "Susceptible" (n=24; triacylglycerol 1% liver wet wt) cows. "Susceptible" cows were assigned randomly to three groups and beginning at d 8 postpartum received 0 (same for "Normal" cows), 2.5, or 5 mg of glucagon in 60 ml 0.15 M NaCl by subcutaneous injections every 8 h for 14 d. Subcutaneous injections of 15 mg/d of glucagon consistently increased concentrations of plasma glucose and insulin for 4 h, decreased concentrations of liver triacylglycerol in cows older than 3.5 years, and tended to decrease concentrations of plasma NEFA and BHBA. The effects of 15 mg/d of glucagon were not limited to the treatment period, because glucagon decreased the incidence of mastitis and days to first ovarian activity after the injection period. These results document that subcutaneous injections of 15 mg/d or glucagon improve metabolic status throughout the injection period and have the potential to treat fatty liver in older cows. The improved metabolic status in cows treated with 15 mg/d of glucagon in early lactation has long-term beneficial effects by improving health status and reproductive performance during the entire lactation.
Download or read book Acute and Chronic Metabolic Responses of Transition Dairy Cows with Fatty Liver Disease to Subcutaneous Glucagon Injections Oral Glycerol Or Both written by Mohamed Abdulraheem Osman and published by . This book was released on 2007 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Metabolic Diseases of Ruminants An Issue of Veterinary Clinics Food Animal Practice written by Thomas Herdt and published by Elsevier Health Sciences. This book was released on 2013-07-28 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: A current, comprehensive issue on metabolic diseases for the food animal practitioner. Topics include obesity and insulin resistance in dairy cows, ketosis therapy, use of serum NEFA and BHBA concentrations in herd-level assessment, mineral nutrition in transition diets, protein, fat, and energy in dairy transition diets, prophylactic calcium therapy in peripartum dairy cows, metabolic regulators of feed intake, assessing and managing body condition score for the prevention of metabolic disease, and more!
Download or read book Prevention of Fatty Liver in Transition Dairy Cows by Subcutaneous Glucagon Injections written by Rafael Albertovich Nafikov and published by . This book was released on 2004 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: The main objective of this study was to test the extent to which subcutaneous glucagon injects for 14 days beginning at d 2 postpartum would prevent fatty liver development in transition dairy cows. Twenty-four multiparous Holstein cows were fed 6 kg of cracked corn in addition to dry cow ration during the last 30 d of a dry period to induce fatty liver development postpartum. Subcutaneous glucagon injections at either 7.5 or 15 mg/d dosages or saline as a control were given 3 times per day for 14 d beginning at d 2 postpartum. Glucagon administration at a dosage of 15 mg/d prevented liver triacylglycerol accumulation and, consequently, fatty liver development in transition dairy cows postpartum. Glucagon administration at 7.5 mg/d dosage showed a potential for fatty liver prevention. Glucagon administration increased plasma glucose and insulin concentrations and decreased plasma nonesterified fatty acid concentration. There were no significant effects of glucagon administration on plasma [beta]-hydroxybutyrate (BHBA) concentration. Cows treated with the 15 mg/d dosage of glucagon, however, tended to show an increase in plasma BHBA concentration around d 9 postpartum. Glucagon had no effects on feed intake and milk production of dairy cows. Moreover, milk consumption was not altered by subcutaneous glucagon injections. Milk urea concentration decreased, and plasma urea concentration tended to decrease during glucagon administration, which indicates that treatment with glucagon may improve protein utilization. Liver glycogen concentration was not affected by glucagon administration. There were no significant differences in body condition scores between cows from different treatment groups throughout the study. Our results show that subcutaneous glucagon injections can be used for fatty liver prevention in transition dairy cows.
Download or read book Ruminant Physiology written by Pierre Cronjé and published by CABI. This book was released on 2000 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: The International Symposium on Ruminant Physiology (ISRP) is the premier forum for presentation and discussion of advances in knowledge of the physiology of ruminant animals. This book brings together edited versions of the keynote review papers presented at the symposium.
Download or read book Metabolic Modifiers written by National Research Council and published by National Academies. This book was released on 1994-02-01 with total page 94 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past decade, animal scientists have learned that administering recombinantly derived somatotropin (growth hormone) to cows improves milk production and that giving beta-adrenergic agonists to meat animals improves productivity and leanness. In order for these metabolic modifiers to yield benefits, however, sound management of the animals' nutrition is necessary. This volume reports on how these substances work in the animals' metabolism, what effects they might have on nutrient requirements of domestic livestock, and what information should be developed further by investigators. The book explores the current understanding of the biology, structure, mechanisms of action, and treatment effects of somatotropin, beta-adrenergic agonists, and anabolic steroids. A companion volume to the Nutrient Requirements of Domestic Animals series, this authoritative volume will be required reading for animal scientists, researchers, veterinarians, livestock farmers, and faculty and students in university animal veterinary science programs.
Download or read book Environmental Physiology of Livestock written by R. J. Collier and published by John Wiley & Sons. This book was released on 2012-02-07 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Environmental stress is one of the most significant factors affecting livestock performance and health, and it is only expected to increase with effects of global warming. Environmental Physiology of Livestock brings together the latest research on environmental physiology, summarizing progress in the field and providing directions for future research. Recent developments in estimating heat stress loads are discussed, as well as key studies in metabolism, reproduction, and genetic expressions. Environmental Physiology of Livestock begins with a survey of current heat indexing tools, highlighting recent discoveries in animal physiology, changes in productivity levels, and new technologies available to better estimate stress response. Using this synopsis as a point of orientation, later chapters hone in on major effects of heat stress, including changing metabolic pathways and nutrient requirements, endocrine regulation of acclimation to environmental stress, and reduced reproductive performance. The text concludes with a thorough discussion of environmental effects on gene expressions, providing important insight for future breeding practices. Environmental Physiology of Livestock is a globally contributed volume and a key resource for animal science researchers, geneticists, and breeders.
Download or read book Fat Detection written by Jean-Pierre Montmayeur and published by CRC Press. This book was released on 2009-09-14 with total page 646 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents the State-of-the-Art in Fat Taste TransductionA bite of cheese, a few potato chips, a delectable piece of bacon - a small taste of high-fat foods often draws you back for more. But why are fatty foods so appealing? Why do we crave them? Fat Detection: Taste, Texture, and Post Ingestive Effects covers the many factors responsible for the se
Download or read book Free Fatty Acid Receptors written by Graeme Milligan and published by Springer. This book was released on 2017-02-08 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the important role free fatty acids (FFA) play as potential drug targets. While FFA have long been considered byproducts of cell metabolism, they are now recognized as ligands that regulate cell and tissue function via G-protein-coupled receptors. At least three receptors have been identified for which FFA appear to be the endogenous ligands.
Download or read book B Group Vitamins written by Jean Guy LeBlanc and published by BoD – Books on Demand. This book was released on 2018-09-26 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: B-group vitamins are involved in numerous metabolic reactions and their widespread deficiency can cause a large series of health problems. The aim of this book is to provide an update on the current use and perspectives of B-group vitamins. Novel methods to detect folates in pregnant women, the use and role of folate dentistry, the use of genotype notification to modify food intake behavior, thiamin metabolism in Archaea and its role in plants and in crop improvement, the use of riboflavin in blood safety and niacin in metabolic stress and resistance in dairy cows are some of the subjects that are described in this multitopic book written by authors from seven different countries.
Download or read book The Role of Chromium in Animal Nutrition written by National Research Council and published by National Academies Press. This book was released on 1997-11-17 with total page 93 pages. Available in PDF, EPUB and Kindle. Book excerpt: The American feed industry manufactures tons of dietary supplements and additives each year for inclusion in the diets of food-producing animals. Some scientists have suggested that chromium should be a key ingredient in nutritional supplements. Controversy exists, however, over whether chromium sources should be approved as feed additives and whether enough data exist to establish dietary requirements. Chromium use has been suggested to have positive impacts on farm profitability, and many animal health benefits have been attributed to chromium supplementation, including increased longevity; enhanced reproduction; decreased incidence of metabolic disorders, stress effects, and disease; reduced need for antibiotic usage; improved immune response; and lean carcass quality. This book addresses recent research on chromium in animal diets; metabolic interactions between chromium and other nutrients; assessments of form and species interactions; supplementation effects; bioavailability of chromium forms and sources; and effects of diet composition, stressors, and animal physiological status on chromium utilization. It also provides recommendations on the essentiality of dietary chromium in domestic animal species and guidelines for use of dietary chromium.
Download or read book Diabetes Mellitus in Children written by Mark A. Sperling and published by . This book was released on 2005 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Farm Animal Metabolism and Nutrition written by J. P. Felix D'Mello and published by CABI. This book was released on 2000 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents specially commissioned reviews of key topics in farm animal metabolism and nutrition, such as repartitioning agents, near infrared reflectance spectroscopy and digestibility and metabolisable energy assays, where major advances have recently been made or which continue to represent issues of significance for students and researchers. Authors include leading researchers from Europe, North America and Australia.
Download or read book Aspirin and Related Drugs written by Kim D. Rainsford and published by CRC Press. This book was released on 2004-10-28 with total page 801 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reviewing over a century of aspirin research and use, Aspirin and Related Drugs provides a comprehensive source of information on the history, chemistry, absorption in the body, therapeutic effects, toxicology, elimination, and future uses of aspirin. Highlighting the historical evolution of the salicylates and the commercial development of
Download or read book Dissertation Abstracts International written by and published by . This book was released on 2004 with total page 854 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Feed efficiency in swine written by John F. Patience and published by Springer Science & Business Media. This book was released on 2012-10-15 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'Feed efficiency in swine' has been prepared as a comprehensive treatise on the current state of our understanding of this topic which is so important to the pork industry. Each chapter is written by international authorities who understand both the science and application of their topic area. The book provides detailed insight into the many factors affecting feed efficiency, ranging from diet processing to herd health, from nutrition to physiology and from day-to-day barn management to the adoption of advanced technologies. The authors explain such practical aspects as the challenge of interpreting feed efficiency information obtained on farm or the role of liquid feeding. The authors also delve into more scientific topics such as amino acid or energy metabolism or animal physiology. This book is written for people who have a technical interest in pork production, including nutritionists, geneticists, farm management specialists, veterinarians, other academics and, of course, pork producers.
