Download or read book Clinical Neurotoxicology E Book written by Michael R. Dobbs and published by Elsevier Health Sciences. This book was released on 2009-07-22 with total page 729 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Neurotoxicology offers accurate, relevant, and comprehensive coverage of a field that has grown tremendously in the last 20 years. You’ll get a current symptomatic approach to treating disorders caused by neurotoxic agents, environmental factors—such as heavy metals and pesticides—and more. Apply discussions of cellular and molecular processes and pathology to clinical neurology. Leading authorities and up-and-coming clinical neurotoxicologists present their expertise on wide-ranging, global subjects and debate controversies in the specialty, including Gulf War Syndrome. Provides a complete listing of neurotoxic agents—from manufactured to environmental—so you get comprehensive, clinical coverage. Covers how toxins manifest themselves according to age and co-morbidity so that you can address the needs of all your patients. Offers broad and in-depth coverage of toxins from all over the world through contributions by leading authorities and up-and-coming clinical neurotoxicologists. Features discussion of controversial and unusual topics such as Gulf War Syndrome, Parkinson’s Disease, motor neuron disease, as well as other issues that are still in question.
Download or read book Medical Toxicology of Drug Abuse written by Donald G. Barceloux and published by John Wiley & Sons. This book was released on 2012-02-03 with total page 1080 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a broad reference covering important drugs of abuse including amphetamines, opiates, and steroids. It also covers psychoactive plants such as caffeine, peyote, and psilocybin. It provides chemical structures, analytical methods, clinical features, and treatments of these drugs of abuse, serving as a highly useful, in-depth supplement to a general medical toxicology book. The style allows for the easy application of the contents to searchable databases and other electronic products, making this an essential resource for practitioners in medical toxicology, industrial hygiene, occupational medicine, pharmaceuticals, environmental organizations, pathology, and related fields.
Download or read book Neurotoxicology written by Louis W. Chang and published by Elsevier. This book was released on 1995-04-20 with total page 875 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurotoxicology: Approaches and Methods provides a unique and comprehensive presentation of the current concepts and state-of-the-art methods for the assessment of neurotoxicity. The book analyzes various techniques available and discusses their strengths and weaknesses. This volume will serve as an excellent desk companion and laboratory guide for all investigators, researchers, clinicians, and students interested in neurotoxicology. The internationally knowngroup of editors divide the book into seven sections: Neuromorphological and Neuropathological Approaches; Neurophysiological Approaches; Neurobehavioral Toxicology; Neurochemical and Biomolecular Approaches; In-Vitro Models; Clinical Neurotoxicology; and Risk Assessment of Neurotoxicity. Each section yields the most up-to-date information by experts in their fields. Meticulously organized and edited, Neurotoxicology: Approaches and Methods is the most authoritative and well-planned neurotoxicology book on the market. - Discusses neurobehavioral testing methods for assessment of neural dysfunctions - Explains state-of-the-art diagnostic methods, such as clinico-neuropsychological and neurophysiological methods, for patients confronted by neurotoxic problems - Discusses In Vitro methods, including aggregating brain cell methods, organotypic cultures, and the use of human neuronal cell lines for the assessment of neurotoxicity - Presents step-by-step procedures for many methods - Provides state-of-the-art neuromorphological and biomolecular methods and approaches for neurotoxicity investigation
Download or read book Experimental and Clinical Neurotoxicology written by Peter S. Spencer and published by Spencer, Experimental and Clin. This book was released on 2000 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Two decades have passed since publication of the first edition of Experimental and Clinical Neurotoxicology pioneered the development of this discipline. Since then no other book has approached the breadth, scholarship, and balance of that landmark volume. For this long-awaited second edition,the original editors have been joined by Albert Ludolf, who brings expertise in biological neurotoxicology, and together with their distinguished contributors they have completely rewritten and reorganized the text.The scientific and clinical foundation is laid in three comprehensive introductory chapters. An overview of the biological basis of neurotoxicity provides the goundwork for discussing the scope of human and veterinary neurotoxic disease.The bulk of the text is devoted to an alphabeticaltreatment of chemicals with neurotoxic potential. This consists of tightly written overviews of the properties, actions, and mechanisms of all manner of substances, whether natural or synthetic. The neurotoxic side effects of experimental agents and of therapeutic as well as abused drugs arecovered extensively. Environmental pollutants, workplace contaminants, personal-use products, food additives, and agents harbored by plants, animals, and humans for use against their respective enemies are discussed. Each substance is rated on a three-point scale for the weight of evidenceindicating a specific neurotoxic effect in humans, animals, or laboratory models. These effects are summarized and cross-referenced in a series of appendices and an extensive index.In summary, the second edition establishes neurotoxicology as a scientific discipline that melds neurobiology, toxicology, and neurology. From this unique vantage point, the book examines in encyclopedic manner several hundred chemicals with the capacity to induce neurological illness in humansand animals. Indispensable for the experimental neuroscientist and toxicologist, as well as for practitioners of human and animal medicine, the book also provides an authoritative, critical, and pithy reference work for specialists in public health and the legal profession.
Download or read book Neurotoxicology written by G. Jean Harry and published by CRC Press. This book was released on 2016-04-19 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new edition presents an integrated approach to neurotoxicology, the study of organisms' responses to changes in their environment and how interruption of the flow of information by chemical exposure causes a wide range of effects - from learning deficits, sensory disturbances in the extremities, and muscle weakness to seizures and signs simila
Download or read book Medical Neurotoxicology written by Peter G. Blain and published by CRC Press. This book was released on 1999-07-30 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: âMedical Neurotoxicologyã is the only up-to-date reference text aimed at the clinician covering both occupational and environmental causes of neurological disease. Although classic occupational poisonings by agents such as heavy metals are now rare in the West, environmental exposure to chemicals such as pesticides or electromagnetic radiation is almost universal - even mild contact can cause subtle psychological or neurological disturbances. One of the unique features of this book is that it provides details of how to examine the patient, how to conduct and interpret epidemiological surveys and how to interpret the signs and symptoms of poisoning - no other text can boast such detailed, step-by-step coverage. The book is aimed at the neurologist and the occupational physician, highlighting topics such as the choice of appropriate tests, differential diagnosis and therapy. However, it will also appeal to clinicians, pharmacists, environmentalists, toxicologists and pharmacologists. With recent cases such as Gulf War Syndrome, and general concern about the effects of chemicals, pesticides and electromagnetic radiation on health, the topic has never been higher in the public consciousness. The effects of exposure to chemical, physical and biological agents, whether at work or in the general environment, are explored in depth. Specific environmental dangers include heavy metals, aluminium, pesticides and solvents. There are also major sections on naturally occurring neuro-toxins, which include poisonous animals and plants, insect-borne diseases and microbiological toxins. Symptoms which the clinician should recognise and ways of assessing a patient are outlined to enable correct diagnosis and management of neurotoxic illnesses.
Download or read book Environmental Neurotoxicology written by National Research Council and published by National Academies Press. This book was released on 1992-02-01 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientists agree that exposure to toxic agents in the environment can cause neurological and psychiatric illnesses ranging from headaches and depression to syndromes resembling parkinsonism. It can even result in death at high exposure levels. The emergence of subclinical neurotoxicity-the concept that long-term impairments can escape clinical detection-makes the need for risk assessment even more critical. This volume paves the way toward definitive solutions, presenting the current consensus on risk assessment and environmental toxicants and offering specific recommendations. The book covers: The biologic basis of neurotoxicity. Progress in the application of biologic markers. Reviews of a wide range of in vitro and in vivo testing techniques. The use of surveillance and epidemiology to identify neurotoxic hazards that escape premarket screening. Research needs. This volume will be an important resource for policymakers, health specialists, researchers, and students.
Download or read book Applied Neurotoxicology An Issue of Neurologic Clinics E Book written by Michael R. Dobbs and published by Elsevier Health Sciences. This book was released on 2020-10-23 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Neurologic Clinics, guest edited by Drs. Michael R. Dobbs and Mam I. Ibraheem, is devoted to Applied Neurotoxicology. This issue is one of four selected each year by the series Consulting Editor, Dr. Randolph W. Evan. Articles in this issue include: Peripheral Neuropathy, Toxin-induced Channelopathies and Neuromuscular Junction Disorders, Myopathy, Acute delirium, Subacute Encephalopathy, Coma and CNS depression, Cerebellar disorders, Parkinsonism, Seizures, Amyotrophic Lateral Sclerosis, Neurobiological Weapons, Women’s and Fetal Issues in Neurotoxicology, and Ethical Dilemmas in Neurotoxicology.
Download or read book Occupational Neurotoxicology written by and published by Academic Press. This book was released on 2022-07-24 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Occupational Neurotoxicology, Volume Seven covers neurotoxicants and exposures to a variety of hazards in the workplace and how they can affect nervous functions in different ways. Metals and organic compounds, both at high level acute exposure and long-term low-level exposure can affect motor functions, cognition, behavior and neurosensory functions. Sections cover Oil leakage in aircraft, aerotoxic syndrome, Organic solvents, WTC neurotoxicities, Environmental intolerance, Pesticides, Carbon monoxide, Mercury Neurotoxicity in Gold Miners, and the Current evolution of neurobehavioral methods. Provides updated information about exposure and neurotoxic outcomes Includes indication on new tools for neurobehavioral assessment Covers practical indications on preventive aspects
Download or read book Neurobehavioral Toxicology Neurological and Neuropsychological Perspectives Volume II written by Stanley Berent and published by Taylor & Francis. This book was released on 2005 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Neurobiology of the Trace Elements written by Ivor E. Dreosti and published by Springer Science & Business Media. This book was released on 1983-10-31 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: F. Macfarlane Burnet I have been an interested onlooker for many years at research on the biology of trace elements, particularly in its bearing on the pas toral and agricultural importance of copper, zinc, cobalt, and mo lybdenum deficiencies in the soil of various parts of Australia. More recently I have developed a rather more specific interest in the role of zinc, particularly in relation to the dominance of zinc metalloenzymes in the processes of DNA replication and repair, and its possible significance for human pathology. One area of special significance is the striking effect of zinc deficiency in the mother in producing congenital abnormalities in the fetus. The fact that several chapters in the present work are concerned with this and other aspects of zinc deficiency is, I fancy, the editors jus tification for inviting me to write this foreword. In reading several of the chpaters before publication, my main impression was of the great potential importance of the topic of trace metal biology in both its negative and positive aspects-the effects of deficiency of essential elements and the toxicity of such pollutants of the modern world as lead or mercury mainly as or ganic compounds.
Download or read book Handbook of Neurotoxicity written by Richard M. Kostrzewa and published by Springer Nature. This book was released on 2023-01-02 with total page 2551 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook is a reference source for identifying, characterizing, instructing on use, and describing outcomes of neurotoxin treatments – to understand mechanisms associated with toxin use; to project outcomes of neurotoxin treatments; to gauge neurotoxins as predictors of events leading to neurodegenerative disorders and as aids to rational use of neurotoxins to model disease entities. Neuroprotection is approached in different manners including those 1) afforded by therapeutic agents – clinical and preclinical; or 2) by non-drug means, such as exercise. The amorphous term ‘neurotoxin’ is discussed in terms of the possible eventuality of a neuroprotectant producing an outcome of excess neuronal survival and a behavioral spectrum that might produce a dysfunction – akin to a neurotoxin’s effect. This new edition significantly expands on the information provided in the first edition, providing the latest research in neurotoxicity and highlighting the relationship between specific neurotoxins and the neurodegenerative disorders they can cause. It also includes new sections on the neurotoxicity of heavy metals, fungi, and snake venom. The Handbook of Neurotoxicity is thus an instructive and valuable guide towards understanding the role of neurotoxins/neurotoxicity in the expansive field of Neuroscience, and is an indispensable tool for laboratory investigators, neuroscientists, and clinical researchers.
Download or read book Experimental Neurotoxicology Methods written by Jordi Llorens and published by Springer Nature. This book was released on 2021-07-23 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores the latest methods that seek to address the vital questions being asked in neurotoxicology research. The chapters in this book cover a variety of available methods from the molecular level to the organism level, and both in vitro and in vivo approaches, including alternative model organisms. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and authoritative, Experimental Neurotoxicology Methods is a valuable resource for both young and experienced researchers who are looking for guidance to implement these methods in their laboratories or for understanding the data generated through these techniques.
Download or read book Neurobehavioral Toxicology Neurological and Neuropsychological Perspectives Volume II written by James W. Albers and published by Taylor & Francis. This book was released on 2005-08-15 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, the second of three volumes, concentrates on peripheral nervous system disorders. Examining the effects of neurotoxicants on nerve, muscle and the neuromuscular junction, it builds on the scientific principles outlined in volume 1 by looking at the application of the methods discussed, particularly in terms of the evaluation and diagnosis of individual patients and the related process of establishing causation. Neurobehavorial Toxicology, Volume 2 will be of interest to practicing neurologists and neuropsychologists, as well as to occupational medicine physicians and medical toxicologists.
Download or read book Cellular and Molecular Neurotoxicology written by Toshio Narahashi and published by Raven Press (ID). This book was released on 1984 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Preserving Brain Health in a Toxic Age written by Arnold R. Eiser and published by Rowman & Littlefield. This book was released on 2021-10-11 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn how to reduce the impact of environmental toxins on brain development, functioning, and health. The human brain is a marvelously complex organ that has evolved great new capabilities over the past 250,000 years. During most of that period, daily life was vastly different from our lives today. Exercise was not optional - one literally had to run for one’s life, livelihood, and sustenance. The Stone Age diet was not a fad, but the only food available. Periods of fasting arose from food scarcity, and hence the earliest keto-diet was commonplace. Life changed greatly with the advent of agriculture and industry. Diseases that were previously unknown or uncommon began to surface as by-products of civilization’s advance. Changes in our ways of living have altered the nature of illness as well as its diagnosis and treatment. From the 1970s to the present, tens of thousands of chemicals with applications in all aspects of our lives have grown more than 40-fold. Exposure to these new substances has impacted many aspects of our health, especially the delicate parts of the brain and nervous system. In parallel with the changes in our environment, we have seen the growth of brain disorders including Alzheimer’s Disease and autism in previously unimaginable ways. Here, Arnold Eiser elucidates some features of diseases affecting the nervous system that are increasing in incidence with a focus on those disorders that appear related to environmental toxins that modern life has introduced. He takes readers behind the scenes of the science itself to discover the human stories involved in the discovery and management of these illnesses. Offering insights from a variety of scientific disciplines, Eiser clearly and succinctly illustrates the impact of toxins on our brains and how we might better protect ourselves from negative outcomes. With interviews from leading authorities in the field of neuroscience, environmental toxicology, integrative medicine, neurology, immunology, geriatrics, and microbiology (re the gut microbiome), this book offers a robust understanding of the complex threats to our brains, and the healthy brain’s dependence upon many other systems within our bodies. This is a voyage of discovery into the science, history, and human struggle regarding disorders challenging the brain as well as their possible prevention.
Download or read book Handbook of Neurotoxicology written by Edward J. Massaro and published by Springer Science & Business Media. This book was released on 2001-11-12 with total page 658 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurotoxicology is a broad and burgeoning field of research. Its growth in recent years can be related, in part, to increased interest in and concern with the fact that a growing number of anthropogenic agents with neurotoxic potential, including pesticides, lead, mercury, and the polytypic bypro ducts of combustion and industrial production, continue to be spewed into and accumulate in the environment. In addition, there is great interest in natural products, including toxins, as sources of therapeutic agents. Indeed, it is well known that many natural toxins of broadly differing structure, produced or accumulated for predatory or defensive purposes, and toxic agents, accumulated incidentally by numerous species, function to perturb nervous tissue. Components of some of these toxins have been shown to be useful therapeutic agents and/or research reagents. Unfor tunately, the environmental accumulation of some neurotoxic ants of anthropogenic ori gin, especially pesticides and metals, has resulted in incidents of human poisoning, some of epidemic proportion, and high levels of morbidity and mortality. Furthermore, an increasing incidence of neurobehavioral disorders, some with baffling symptoms, is confronting clinicians. It is not clear whether this is merely the result of increased vigi lance and/or improved diagnostics or a consequence of improved health care. In any case, the role of exposure to environmental and occupational neurotoxic ants in the etiology of these phenomena, as well as neurodegenerative diseases, is coming under increasing scrutiny and investigation.
