Download or read book Mechanisms of Gastrointestinal Motility and Secretion written by A. Bennett and published by Springer Science & Business Media. This book was released on 2013-03-13 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Colonic Motility written by Sushil K. Sarna and published by Biota Publishing. This book was released on 2010-11-01 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt: Three distinct types of contractions perform colonic motility functions. Rhythmic phasic contractions (RPCs) cause slow net distal propulsion with extensive mixing/turning over. Infrequently occurring giant migrating contractions (GMCs) produce mass movements. Tonic contractions aid RPCs in their motor function. The spatiotemporal patterns of these contractions differ markedly. The amplitude and distance of propagation of a GMC are several-fold larger than those of an RPC. The enteric neurons and smooth muscle cells are the core regulators of all three types of contractions. The regulation of contractions by these mechanisms is modifiable by extrinsic factors: CNS, autonomic neurons, hormones, inflammatory mediators, and stress mediators. Only the GMCs produce descending inhibition, which accommodates the large bolus being propelled without increasing muscle tone. The strong compression of the colon wall generates afferent signals that are below nociceptive threshold in healthy subjects. However, these signals become nociceptive; if the amplitudes of GMCs increase, afferent nerves become hypersensitive, or descending inhibition is impaired. The GMCs also provide the force for rapid propulsion of feces and descending inhibition to relax the internal anal sphincter during defecation. The dysregulation of GMCs is a major factor in colonic motility disorders: irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and diverticular disease (DD). Frequent mass movements by GMCs cause diarrhea in diarrhea predominant IBS, IBD, and DD, while a decrease in the frequency of GMCs causes constipation. The GMCs generate the afferent signals for intermittent short-lived episodes of abdominal cramping in these disorders. Epigenetic dysregulation due to adverse events in early life is one of the major factors in generating the symptoms of IBS in adulthood.
Download or read book Mechanisms of Gastrointestinal Motility and Secretion written by Alan Bennett and published by . This book was released on 1984 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Mechanisms of Gastrointestinal Motility and Secretion written by A. Bennett and published by . This book was released on 2014-09-01 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Introduction to Basics of Pharmacology and Toxicology written by Abialbon Paul and published by Springer Nature. This book was released on 2021-03-13 with total page 1156 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explains the pharmacological relationships between the various systems in the human body. It offers a comprehensive overview of the pharmacology concerning the autonomic, central, and peripheral nervous systems. Presenting up-to-date information on chemical mediators and their significance, it highlights the therapeutic aspects of several diseases affecting the cardiovascular, renal, respiratory, gastrointestinal, endocrinal, and hematopoietic systems. The book also includes drug therapy for microbial and neoplastic diseases. It also comprises sections on immunopharmacology, dermatological, and ocular pharmacology providing valuable insights into these emerging and recent topics. Covering the diverse groups of drugs acting on different systems, the book reviews their actions, clinical uses, adverse effects, interactions, and subcellular mechanisms of action. It is divided into 11 parts, subdivided into several chapters that evaluate the basic pharmacological principles that govern the different types of body systems. This book is intended for academicians, researchers, and clinicians in industry and academic institutions in pharmaceutical, pharmacological sciences, pharmacy, medical sciences, physiology, neurosciences, biochemistry, molecular biology and other allied health sciences.
Download or read book Neural Control of Gastrointestinal Function written by David Grundy and published by Morgan & Claypool Publishers. This book was released on 2011-12 with total page 137 pages. Available in PDF, EPUB and Kindle. Book excerpt: The gastrointestinal tract is a long, muscular tube responsible for the digestion of food, assimilation of nutrients and elimination of waste. This is achieved by secretion of digestive enzymes and absorption from the intestinal lumen, with different regions playing specific roles in the processing of specific nutrients. These regions come into play sequentially as ingested material is moved along the length of the GI tract by contractions of the muscle layers. In some regions like the oesophagus transit it rapid and measured in seconds while in others like the colon transit is measured in hours and even days, commensurate with the relative slow fermentation that takes place in the large bowel. An hierarchy of controls, neural and endocrine, serve to regulate the various cellular targets that exist in the gut wall. These include muscle cells for contraction and epithelial cells for secretion and absorption. However, there are complex interactions between these digestive mechanisms and other mechanisms that regulate blood flow, immune function, endocrine secretion and food intake. These ensure a fine balance between the ostensibly conflicting tasks of digestion and absorption and protection from potentially harmful ingested materials. They match assimilation of nutrients with hunger and satiety and they ensure that regions of the GI tract that are meters apart work together in a coordinated fashion to match these diverse functions to the digestive needs of the individual. This ebook will provide an overview of the neural mechanisms that control gastrointestinal function. Table of Contents: Neural Control of Gastrointestinal Function / Cells and Tissues / Enteric Nervous System / From Gut to CNS: Extrinsic Sensory Innervation / Sympathetic Innervation of the Gut / Parasympathetic Innervation of the Gut / Integration of Function / References
Download or read book The Enteric Nervous System written by John Barton Furness and published by . This book was released on 1987 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Fundamentals of Anaesthesia written by Colin Pinnock and published by Cambridge University Press. This book was released on 2002-12 with total page 990 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of Fundamentals of Anaesthesia builds upon the success of the first edition, and encapsulates the modern practice of anaesthesia in a single volume. Written and edited by a team of expert contributors, it provides a comprehensive but easily readable account of all of the information required by the FRCA Primary examination candidate and has been expanded to include more detail on all topics and to include new topics now covered in the examination. As with the previous edition, presentation of information is clear and concise, with the use of lists, tables, summary boxes and line illustrations where necessary to highlight important information and aid the understanding of complex topics. Great care has been taken to ensure an unrivalled consistency of style and presentation throughout.
Download or read book Oxford Textbook of Critical Care written by Webb and published by Oxford University Press. This book was released on 2020-01-10 with total page 1961 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in paperback, the second edition of the Oxford Textbook of Critical Care is a comprehensive multi-disciplinary text covering all aspects of adult intensive care management. Uniquely this text takes a problem-orientated approach providing a key resource for daily clinical issues in the intensive care unit. The text is organized into short topics allowing readers to rapidly access authoritative information on specific clinical problems. Each topic refers to basic physiological principles and provides up-to-date treatment advice supported by references to the most vital literature. Where international differences exist in clinical practice, authors cover alternative views. Key messages summarise each topic in order to aid quick review and decision making. Edited and written by an international group of recognized experts from many disciplines, the second edition of the Oxford Textbook of Critical Careprovides an up-to-date reference that is relevant for intensive care units and emergency departments globally. This volume is the definitive text for all health care providers, including physicians, nurses, respiratory therapists, and other allied health professionals who take care of critically ill patients.
Download or read book Gastrointestinal Motility written by D. Grundy and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: The basis of this book is a ten-lecture course on the control of gastrointesti nal motility given each year to the final year undergraduate students in Physiology at Sheffield University. A naive thought led me to believe that the conversion of my lecture notes into the present book would be a relatively easy task. I now know differently. As there is no equivalent undergraduate course elsewhere that I know of, it would be dishonest of me to claim this book to be an undergraduate text. The comprehensive way in which I have dealt with the subject, together with the inclusion of the most up-to-date material, make the book more relevant to postgraduate students of physiology, medicine and related sciences who require an introduction to the field of gastrointestinal motility and its control. I have, however, attempted to present the current concepts on the physiological mechanisms regulating motility in a way which under graduates, as well as postgraduates, will find readable, informative and, hopefully, enjoyable.
Download or read book Gastrointestinal Physiology written by Menizibeya Osain Welcome and published by Springer. This book was released on 2018-06-20 with total page 1028 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers one of the most comprehensive reviews in the field of gastrointestinal (GI) physiology, guiding readers on a journey through the complete digestive tract, while also highlighting related organs and glandular systems. It is not solely limited to organ system physiology, and related disciplines like anatomy and histology, but also examines the molecular and cellular processes that keep the digestive system running. As such, the book provides extensive information on the molecular, cellular, tissue, organ, and system levels of functions in the GI system. Chapters on the roles of the gut as an endocrine, exocrine and neural organ, as well as its microbiome functions, broaden readers’ understanding of the multi-organ networks in the human body. To help illustrate the interconnections between the physiological concepts, principles and clinical presentations, it outlines clinical examples such as pathologies that link basic science with clinical practice in special “clinical correlates” sections. Covering both traditional and contemporary topics, it is a valuable resource for biomedical students, as well as healthcare and scientific professionals.
Download or read book Yamada s Textbook of Gastroenterology written by Daniel K. Podolsky and published by John Wiley & Sons. This book was released on 2015-10-22 with total page 16819 pages. Available in PDF, EPUB and Kindle. Book excerpt: Seit 20 Jahren ist Yamada's Textbook of Gastroenterology das umfassendste und weltweit anerkannte Lehrwerk für das Fachgebiet und vereint in Form einer Enzyklopädie die wissenschaftlichen Grundlagen von Magen-Darm- und Lebererkrankungen mit den neuesten klinischen Erkenntnissen, vor allem Entwicklungen in den Bereichen Diagnose und Therapie. Zu dem Herausgeberteam unter der Leitung von Tachi Yamada, einer der weltweit führenden Forscher des Fachgebiets, gehörten schon immer herausragende Namen. Gleiches gilt für die Autoren vieler Beiträge, die zu den Experten ihres Fachbereichs gehören. Mit dem neuen Chefherausgeber Dan Podolsky, Professor für Innere Medizin an dem Southwestern Medical Center der University of Texas, wurde die 6. Auflage dieses führenden Lehrbuchs aktualisiert und in vielerlei Hinsicht verbessert - Jetzt beim Kauf der Printversion mit kostenlosem Zugriff auf die digitale Ausgabe mit umfassenden Suchfunktionen. - Einheitliche Darstellung der einzelnen Themenabschnitte, unterteilt in wissenschaftliche Grundlagen, Krankheiten und deren Symptome, und damit eine Vereinheitlichung in Aufbau, Inhalt und Länge. - Neuer Abschnitt "Principles of Clinical Gastroenterology" mit Schwerpunkt auf klinische Aspekte. In 14 Kapiteln wird auf die jeweiligen Krankheitssymptome eingegangen. Ärzte können so ihre Patienten in der Klinik noch besser beurteilen und behandeln. - Wichtige Themen werden noch ausführlicher erläutert (autoimmune Pankreatitis, fäkale Biomarker, Genetik, chronisch-entzündliche Darmerkrankungen, systemische IgG4-assoziierte Erkrankungen, Morbus Crohn, Colitis ulcerosa und eosinophile Ösophagitis). - Podcasts international führender Experten zu aktuellen Themen. - Stärkerer Schwerpunkt auf klinische Studien/Versuchsreihen, evidenzbasierte Praxis, Richtlinien von Fachverbänden und Regierungsstellen. - Verweise auf Online-Referenzwerke, Hyperlinks zu Pubmed/CrossRef. Die wichtigsten Verweise sind weiterhin in der Printversion enthalten. - Noch internationaler und global: Neben den führenden Experten aus Nordamerika kommen renommierte Fachärzte aus Europa und Asien zu Wort. Yamada's Textbook of Gastroenterology ist das umfassende Standardwerk der Gastroenterologie. Die 6. Auflage orientiert sich noch stärker am Klinikalltag, ist aufgrund der Fülle an Informationen zu wissenschaftlichen Grundlagen nach wie vor Marktführer und gleichzeitig ein herausragendes Referenzwerk zum klinischen Management von Erkrankungen des Magen-Darm-Trakts. Jetzt noch besser: Kostenloser Online-Zugang zu allen Inhalten der Printausgabe mit weitreichenden Suchfunktionen. Genau das Richtige für Gastroenterologen, ob erfahrener Praktiker oder Berufsanfänger.
Download or read book Incretins and Insulin Secretion written by and published by Academic Press. This book was released on 2010-12-16 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology, and enzyme mechanisms. Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists, and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and vitamins will, as always, turn to this series for comprehensive reviews by leading contributors to this and related disciplines. This volume focuses on insulin and IGFs. Longest running series published by Academic Press Contributions by leading international authorities
Download or read book Relationships Among the Brain the Digestive System and Eating Behavior written by Institute of Medicine and published by National Academies Press. This book was released on 2015-02-27 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: On July 9-10, 2014, the Institute of Medicine's Food Forum hosted a public workshop to explore emerging and rapidly developing research on relationships among the brain, the digestive system, and eating behavior. Drawing on expertise from the fields of nutrition and food science, animal and human physiology and behavior, and psychology and psychiatry as well as related fields, the purpose of the workshop was to (1) review current knowledge on the relationship between the brain and eating behavior, explore the interaction between the brain and the digestive system, and consider what is known about the brain's role in eating patterns and consumer choice; (2) evaluate current methods used to determine the impact of food on brain activity and eating behavior; and (3) identify gaps in knowledge and articulate a theoretical framework for future research. Relationships among the Brain, the Digestive System, and Eating Behavior summarizes the presentations and discussion of the workshop.
Download or read book Anatomy and Physiology written by J. Gordon Betts and published by . This book was released on 2013-04-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Basic Physiology for Anaesthetists written by David Chambers and published by Cambridge University Press. This book was released on 2019-07-25 with total page 469 pages. Available in PDF, EPUB and Kindle. Book excerpt: Easily understood, up-to-date and clinically relevant, this book provides junior anaesthetists with an essential physiology resource.
Download or read book Autonomic Neurology written by Eduardo E. Benarroch and published by Oxford University Press. This book was released on 2014-04-03 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this book is to present a focused approach to the pathophysiology, diagnosis, and management of the most common autonomic disorders that may present to the clinical neurologist. Autonomic Neurology is divided into 3 sections. The first section includes 5 chapters reviewing the anatomical and biochemical mechanisms of central and peripheral nervous system control of autonomic function, principles of autonomic pharmacology, and a clinical and laboratory approach to the diagnosis of autonomic disorders. The second section focuses on the pathophysiology and management of orthostatic hypotension, postural tachycardia, baroreflex failure; syncope, disorders of sweating, neurogenic bladder and sexual dysfunction, gastrointestinal dysmotility, and autonomic hyperactivity. The final section is devoted to specific autonomic disorders, including central neurodegenerative disorders; common peripheral neuropathies with prominent autonomic failure; painful small fiber neuropathies; autoimmune autonomic ganglionopathies and neuropathies; focal brain disorders; focal spinal cord disorders; and chronic pain disorders with autonomic manifestations. This book is the product of the extensive experience of its contributors in the evaluation and management of the many patients with autonomic symptoms who are referred for neurologic consultation at Mayo Clinic in Rochester, Minnesota. Autonomic Neurology focuses on clinical scenarios and presentation of clinical cases and includes several figures showing the results of normal and abnormal autonomic testing in typical conditions. Its abundance of tables summarizing the differential diagnosis, testing, and management of autonomic disorders also help set this book apart from other books focused on the autonomic nervous system.
