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Book Mechanisms and Novel Therapies in Graves    Orbitopathy  Current Update

Download or read book Mechanisms and Novel Therapies in Graves Orbitopathy Current Update written by Kelvin Kam-Lung Chong and published by Frontiers Media SA. This book was released on 2022-05-24 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Graves  Orbitopathy

    Book Details:
  • Author : W.M. Wiersinga
  • Publisher : Karger Medical and Scientific Publishers
  • Release : 2010-08-17
  • ISBN : 3805595328
  • Pages : 300 pages

Download or read book Graves Orbitopathy written by W.M. Wiersinga and published by Karger Medical and Scientific Publishers. This book was released on 2010-08-17 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: The significant progress in the understanding of the pathogenesis and the treatment of Graves’ orbitopathy (GO) has warranted a second edition of this book within three years of the first. Now also fully incorporated is the EUGOGO consensus statement on management of GO, which since has been accepted worldwide as a useful guideline. Furthermore all chapters have been thoroughly updated. Subjects covered include the pathology of GO and the controversial views on its pathogenesis; assessment of changes using reliable measuring techniques; medical management of GO including established and alternative treatment options; technical explanations and illustrations of various surgical procedures and finally, the molecular, immunologic, and clinical aspects of this complex disorder. Two new chapters have been added: one describing the socioeconomic impact of the disease and the other outlining the Amsterdam Declaration on Graves’ Orbitopathy. The successful question-and-answer format facilitates its use as a reference guide for medical practitioners and surgeons working in the fields of ophthalmology, internal medicine, endocrinology, pediatrics, immunology, as well as otorhinolaryngology.

Book Thyroid Autoimmunity

    Book Details:
  • Author : A. Pinchera
  • Publisher : Springer Science & Business Media
  • Release : 2012-12-06
  • ISBN : 146130945X
  • Pages : 579 pages

Download or read book Thyroid Autoimmunity written by A. Pinchera and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 579 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1956, three groups independently reported evidence that some thyroid disease appearing spontaneously in humans or experimentally induced in animals are related to autoimmune processes. The interval between these landmark discoveries and the present has witnessed a remarkable and continuing growth of both knowledge and concepts concerning the mechanisms of immune regulation, the pathogenesis of autoimmune thyroid diseases, and their clinical and laboratory manifestations. More importantly knowledge of thyroid autoimmunity has, in many respects, comprised the vanguard of an ever increasing appreciation and understanding of autoimmune diseases in general. On November 24-26 1986, an International Symposium on Thyroid Autoimmunity was held in Pisa. Its purpose was to commemorate the birth of thyroid autoimmunity as a scientific discipline, to summarize current knowledge and concepts in this area, and where possible, to anticipate areas of opportunity for the future - hence the theme of the Symposium, Memories and Perspectives. To open the meeting, the Magnifico Rettore (Chancellor) of the University of Pisa granted special Awards to Dr. Deborah Doniach, Dr. Ivan Roitt, and Dr. Noel R. Rose, who published the first fundamental studies in the field of thyroid autoimmunity, and to Dr. Duncan G. Adams, whose discovery of the long-acting thyroid stimulator (LATS) opened the door to our current understanding of the pathogenesis of Graves' disease. During the meeting thirty plenary lectures were presented.

Book Graves  Orbitopathy

    Book Details:
  • Author : Wilmar M. Wiersinga
  • Publisher : Karger Medical and Scientific Publishers
  • Release : 2007
  • ISBN : 3805583427
  • Pages : 275 pages

Download or read book Graves Orbitopathy written by Wilmar M. Wiersinga and published by Karger Medical and Scientific Publishers. This book was released on 2007 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, close interdisciplinary cooperation of numerous international experts, both clinicians and basic scientists, within the European Group of Graves' orbitopathy (EUGOGO) has yielded much valuable progress and new information, which this publication brings together. Subjects covered include the pathology of Graves' orbitopathy (GO) and the controversial views on its pathogenesis; assessment of changes using reliable measuring techniques; medical management of GO including established and alternative treatment options; technical explanations and illustrations of various surgical procedures and finally, the molecular, immunologic, and clinical aspects of this complex disorder. Stressing the current management of thyroid eye disease, this book offers medical practitioners a thorough overview of associated changes in the eyes of patients with GO. Therefore, this publication is an essential resource for ophthalmologists, internists, endocrinologists, pediatricians, immunologists, specialists in nuclear medicine, neuroradiologists and radiotherapists, specialists in laboratory medicine and pathology, otorhinolaryngologists, orbital and neurosurgeons as well as oral and maxillofacial surgeons.

Book Encyclopedia of Molecular Pharmacology

Download or read book Encyclopedia of Molecular Pharmacology written by Stefan Offermanns and published by Springer Science & Business Media. This book was released on 2008-08-14 with total page 1515 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential text, this is a fully updated second edition of a classic, now in two volumes. It provides rapid access to information on molecular pharmacology for research scientists, clinicians and advanced students. With the A-Z format of over 2,000 entries, around 350 authors provide a complete reference to the area of molecular pharmacology. The book combines the knowledge of classic pharmacology with the more recent approach of the precise analysis of the molecular mechanisms by which drugs exert their effects. Short keyword entries define common acronyms, terms and phrases. In addition, detailed essays provide in-depth information on drugs, cellular processes, molecular targets, techniques, molecular mechanisms, and general principles.

Book Oxford Textbook of Endocrinology and Diabetes

Download or read book Oxford Textbook of Endocrinology and Diabetes written by John A.H. Wass and published by Oxford University Press, USA. This book was released on 2011-07-28 with total page 2158 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its second edition, the Oxford Textbook of Endocrinology and Diabetes is a fully comprehensive, evidence-based, and highly-valued reference work combining basic science with clinical guidance, and providing first rate advice on diagnosis and treatment.

Book Immune Checkpoint Inhibitors in Cancer

Download or read book Immune Checkpoint Inhibitors in Cancer written by Fumito Ito and published by Elsevier Health Sciences. This book was released on 2018-09-03 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Get a quick, expert overview of the latest clinical information and guidelines for cancer checkpoint inhibitors and their implications for specific types of cancers. This practical title by Drs. Fumito Ito and Marc Ernstoff synthesizes the most up-to-date research and clinical guidance available on immune checkpoint inhibitors and presents this information in a compact, easy-to-digest resource. It’s an ideal concise reference for trainee and practicing medical oncologists, as well as those in research. Discusses the current understanding of how to best harness the immune system against different types of cancer at various stages. Helps you translate current research and literature into practical information for daily practice. Presents information logically organized by disease site. Covers tumor immunology and biology; toxicities associated with immune checkpoint inhibitors; and future outlooks. Consolidates today’s available information on this timely topic into one convenient resource.

Book The Thyroid and Its Diseases

Download or read book The Thyroid and Its Diseases written by Markus Luster and published by Springer. This book was released on 2019-01-08 with total page 770 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an up-to-date and comprehensive guide to all the common thyroid disorders that may be seen by internists, endocrinologists, nuclear medicine physicians, and endocrine surgeons. While the fundamentals of thyroid hormone function and regulation in health and disease are well covered, the primary focus is on the clinical approach to thyroid disease, with detailed coverage of both initial diagnosis and management and the role of imaging. Because most endocrine diseases are chronic and lifelong, special emphasis is placed on long-term management and the common pitfalls that may be encountered by the clinician. The editors are internationally acknowledged leaders in the field of thyroid disease and have gathered an outstanding team of authors, all of whom are also highly expert in their respective areas, but who, equally importantly, write in a clear and lucid style. The numerous isotope scan and ultrasonographic images ensure that the book will serve as a valuable reference atlas to which the physician will return again and again.

Book Transition of Care

    Book Details:
  • Author : M. Polak
  • Publisher : Karger Medical and Scientific Publishers
  • Release : 2018-06-11
  • ISBN : 3318061433
  • Pages : 170 pages

Download or read book Transition of Care written by M. Polak and published by Karger Medical and Scientific Publishers. This book was released on 2018-06-11 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pediatricians face many questions and challenges during patients’ transition from childhood to adulthood. Chronic diseases justify long-term medical, psychological, educational, and social management. The establishment of networks with adult endocrinologists is, therefore, very important to achieving optimal conditions for a successful transition period. In this book, leading experts discuss major public health issues such as diabetes and obesity. They also review genetic diseases, including Turner syndrome and congenital adrenal hyperplasia. All clinical cases are presented in a focused way to highlight any issues which might be discussed by the doctor with patients and family. Psychological approaches are debated as are proposals for defining specific tools to encourage autonomy during this life period. This book is a valuable tool and will be helpful in answering many questions for endocrinologists, adult and pediatric, dedicated to the long-term management of patients with chronic diseases.

Book Goiter

    Book Details:
  • Author : N.K. Agrawal
  • Publisher : BoD – Books on Demand
  • Release : 2020-04-08
  • ISBN : 1789859638
  • Pages : 146 pages

Download or read book Goiter written by N.K. Agrawal and published by BoD – Books on Demand. This book was released on 2020-04-08 with total page 146 pages. Available in PDF, EPUB and Kindle. Book excerpt: The thyroid gland is a commonly diseased endocrine organ of human body. The disorders affecting the thyroid gland are varied but are very much amenable to treatment. The enlargement of the thyroid is termed goiter. It can affect the whole gland or only part of it. The disease is perplexing but in-depth knowledge of the pathophysiology helps in elucidating causes and thereby treating the disease. In this book, the diffuse and nodular goiter has been addressed as well as the functional abnormalities of the gland and its implications on the body are discussed in various chapters. The relevant updated information is included. To address a few of these current issues and recent updated information, authors have put in a lot of effort to organize the book.

Book Encyclopedia of the Neurological Sciences

Download or read book Encyclopedia of the Neurological Sciences written by and published by Academic Press. This book was released on 2014-04-29 with total page 4744 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Encyclopedia of the Neurological Sciences, Second Edition, Four Volume Set develops from the first edition, covering all areas of neurological sciences through over 1000 entries focused on a wide variety of topics in neurology, neurosurgery, psychiatry and other related areas of neuroscience. The contributing authors represent all aspects of neurology from many viewpoints and disciplines to provide a complete overview of the field. Entries are designed to be understandable without detailed background knowledge in the subject matter, and cross-referencing and suggested further reading lead the reader from a basic knowledge of the subject to more advanced understanding. The easy-to-use 'encyclopedic-dictionary' format of the Encyclopedia of the Neurological Sciences, Second Edition features alphabetic entries, extensive cross-referencing, and a thorough index for quick reference. The wealth of information provided by these four volumes makes this reference work a trusted source of valuable information for a wide range of researchers, from undergraduate students to academic researchers. Provides comprehensive coverage of the field of neurological science in over 1,000 entries in 4 volumes "Encyclopedic-dictionary" format provides for concise, readable entries and easy searching Presents complete, up-to-date information on 32 separate areas of neurology Entries are supplemented with extensive cross-referencing, useful references to primary research articles, and an extensive index

Book Thyroid Diseases

    Book Details:
  • Author : Paolo Vitti
  • Publisher : Springer
  • Release : 2018-09-09
  • ISBN : 9783319450124
  • Pages : 770 pages

Download or read book Thyroid Diseases written by Paolo Vitti and published by Springer. This book was released on 2018-09-09 with total page 770 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the latest advances in knowledge of the pathogenesis of thyroid diseases and describes the state of the art in their diagnosis and treatment, including newly emerging management approaches. After an opening section that addresses thyroid physiology and laboratory evaluation, each of the major thyroid diseases and their subtypes is discussed, covering goiter and thyroid nodule, thyroiditis, hypothyroidism, hyperthyroidism and thyrotoxicosis, and thyroid carcinoma. Other conditions that affect thyroid function or induce thyroid dysfunction are also considered, e.g., pregnancy, non-thyroidal disorders, and medication use. The book is designed to assist practitioners to achieve optimal outcomes in clinical routine by providing clear guidance on clinical examination, the use of diagnostic tests, first- and second-line therapies, and follow-up. Chapter have been written by recognized experts in the field.

Book Controversies in Neuro Ophthalmic Management

Download or read book Controversies in Neuro Ophthalmic Management written by Amanda D. Henderson and published by Springer Nature. This book was released on 2021-06-25 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book functions as a resource for providers who treat patients with neuro-ophthalmic conditions. Using an evidence-based approach to controversial management decisions, the material is presented in a digestible, case-based format. Divided into six sections, the book begins with an introduction to its framework, format, and purpose. Following this, sections two, three, and four discuss various optic neuropathies, ocular motility disorders, and transient visual symptoms. The concluding sections then address neuro-ophthalmic manifestations of pain, including migraine and post-concussive syndrome, and systemic diseases, such as giant cell arteritis. Each chapter focuses on cases that are historically complex, or which have undergone a recent shift in traditional management due to new scientific discoveries or newly available therapies. Controversies in Neuro-Ophthalmic Management presents essential, thorough information on management options and the data for their use to provide the best care for patients.

Book The Parathyroids

    Book Details:
  • Author : John P. Bilezikian
  • Publisher : Elsevier
  • Release : 2001-07-21
  • ISBN : 0080525776
  • Pages : 921 pages

Download or read book The Parathyroids written by John P. Bilezikian and published by Elsevier. This book was released on 2001-07-21 with total page 921 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by world experts, this books follows upon the monumental success of the first edition of The Parathyroids, which was universally acclaimed as the best text on the subject. An authoritative reference that spans the basic science of parathyroid hormone treatment to major clinical disorders in a superb, single compendium, The Parathyroids offers an objective and authoritative view on controversial clinical issues in this rapidly changing field. Every medical school library and virtually every major hospital library will need this book as a reference for students and clinicians. Key Features * Offers objective and authoritative reviews on controversial clinical issues * Written by world experts on parathyroid hormone and its disorders * Superb, state-of-the-art compendium in one convenient volume * Bridges basic science of parathyroid hormone to major clinical disorders * Practical information on clinical management of parathyroid hormone disorders

Book Emergencies of the Orbit and Adnexa

Download or read book Emergencies of the Orbit and Adnexa written by Bipasha Mukherjee and published by Springer. This book was released on 2016-12-15 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook on orbital, lacrimal and eyelid emergencies deals with such situations in a practical manner guiding the ophthalmologists in accurate handling and making them more proficient and confident in managing vision and life-threatening emergencies. With 51 chapters and more than 350 images, this book covers all the eye emergencies that generalist and specialist ophthalmologists can expect to come across in their day to day practices. It can be argued that the orbit can no more be called ‘Pandora’s Box’ because of the unpredictable nature of its contents. This perception has changed over the years due to the advent of improved diagnostic, in particular, imaging techniques. However, since medical residency provides very little exposure to orbital and adnexal disorders, most clinicians are inexperienced and unsure about their management. Facing an emergency situation where improper management can rapidly worsen the condition leading to blindness or even death of the patient is every ophthalmologist’s nightmare. The emergent nature of these conditions does not always provide for a leeway to refer these patients to an orbit and oculoplasty specialist, who are few and far between. By the time the patient reaches his destination, his vision maybe irrevocably lost. The legal implications of such mismanagement can be significant too. This book is a quick and essential resource to manage and refer eye emergencies with confidence.

Book Graves  Orbitopathy

    Book Details:
  • Author : W.M. Wiersinga
  • Publisher : Karger Medical and Scientific Publishers
  • Release : 2017-08-21
  • ISBN : 3318060852
  • Pages : 378 pages

Download or read book Graves Orbitopathy written by W.M. Wiersinga and published by Karger Medical and Scientific Publishers. This book was released on 2017-08-21 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ten years ago, the first edition of Graves’ Orbitopathy: A Multidisciplinary Approach was published. Since then, the book has become very popular and much has happened in the field to warrant a third edition. What has not changed is the successful and attractive question-and-answer format of the book. In the 3rd, revised and expanded edition, new chapters have been added on co-morbidity, local treatment modalities, novel immunosuppressive therapy, detailed protocols, and questions frequently asked by patients. All chapters of the previous edition have been thoroughly updated. Subjects covered then include the pathology of Graves’ Orbitopathy (GO) and the controversial views on its pathogenesis; assessment of changes using reliable measuring techniques; medical management of GO including established and alternative treatment options; technical explanations and illustrations of various surgical procedures; and finally, the molecular, immunologic, and clinical aspects of this complex disorder. Additionally, ample consideration is given to the new 2016 ETA/EUGOGO guidelines on the management of GO.

Book Graves    Disease

    Book Details:
  • Author : Basil Rapoport
  • Publisher : Springer Science & Business Media
  • Release : 2012-12-06
  • ISBN : 1461544076
  • Pages : 328 pages

Download or read book Graves Disease written by Basil Rapoport and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: From the perspective of the investigator, Graves' disease is a fascinating disorder with unique features and opportunities for study. The discovery in 1956 that Graves' disease was caused by a humoral factor, later shown to be an antibody to the TSH receptor, was a triumph for modern investigative medicine. Rapid progress is now being made in (i) understanding the molecular interaction between autoantibodies and the TSH receptor, (ii) identifying the genes that contribute to the predisposition to disease, (iii) developing an animal model of Graves' disease, and (iv) identifying the long-sought orbital antigen in ophthalmopathy. From the clinical standpoint, although Graves' disease is eminently treatable, there is no definitive cure. None of the therapeutic options are ideal. It is hoped that rapid progress in understanding the pathogenesis of the disease will lead to the ultimate goal of some form of immunotherapy that will make antithyroid drugs, radioiodine and thyroidectomy obsolete. The chapters in Graves' Disease: Pathogenesis and Treatment represent the viewpoints of many prominent clinicians and investigators working in the field. The editors are grateful for their contributions which cover an unusually comprehensive compendium of subjects relating to the disease.