Download or read book Mechanisms of Vascular Disease written by Robert Fitridge and published by University of Adelaide Press. This book was released on 2011 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.
Download or read book Pain Management and the Opioid Epidemic written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-09-28 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.
Download or read book Pain Modulation written by Howard L. Fields and published by Elsevier Publishing Company. This book was released on 1988-01-01 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume represents edited material that was presented at a conference on brainstem modulation of spinal nociception held in Beaune, France during July, 1987. Pain Modulation, Volume 77 in the series Progress in Brain Research reviews, analyses and suggests new research strategies on several relevant topics including: the endogenous opioid peptides; sites of action of opiates; the role of biogenic animes and non-opioid peptides in analgesia; dorsal horn circuitry; behavioural factors in the activation of pain modulating networks and clinical studies of nociceptive modulation.
Download or read book Pain and Disability written by Institute of Medicine and published by National Academies Press. This book was released on 1987-01-01 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: Painâ€"it is the most common complaint presented to physicians. Yet pain is subjectiveâ€"it cannot be measured directly and is difficult to validate. Evaluating claims based on pain poses major problems for the Social Security Administration (SSA) and other disability insurers. This volume covers the epidemiology and physiology of pain; psychosocial contributions to pain and illness behavior; promising ways of assessing and measuring chronic pain and dysfunction; clinical aspects of prevention, diagnosis, treatment, and rehabilitation; and how the SSA's benefit structure and administrative procedures may affect pain complaints.
Download or read book Mechanism and Control of Pain written by Louis Irving Grossman and published by . This book was released on 1979 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Magnesium in the Central Nervous System written by Robert Vink and published by University of Adelaide Press. This book was released on 2011 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.
Download or read book Sickle Cell Pain written by Samir K. Ballas and published by Lippincott Williams & Wilkins. This book was released on 2015-06-01 with total page 1004 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sickle Cell Pain is a panoramic, in-depth exploration of every scientific, human, and social dimension of this cruel disease. This comprehensive, definitive work is unique in that it is the only book devoted to sickle cell pain, as opposed to general aspects of the disease. The 752-page book links sickle cell pain to basic, clinical, and translational research, addressing various aspects of sickle pain from molecular biology to the psychosocial aspects of the disease. Supplemented with patient narratives, case studies, and visual art, Sickle Cell Pain’s scientific rigor extends through its discussion of analgesic pharmacology, including abuse-deterrent formulations. The book also addresses in great detail inequities in access to care, stereotyping and stigmatization of patients, the implications of rapidly evolving models of care, and recent legislation and litigation and their consequences.
Download or read book Psychological Mechanisms of Pain and Analgesia written by Donald D. Price and published by Progress in Pain Research and. This book was released on 1999 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Pain Mechanisms and Management written by S. N. Ayapetian and published by IOS Press. This book was released on 1998 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: The overall themes of this book are recent advances in mechanisms of pain and the application of those in clinics. Specific attention is paid to developing countries where practice of pain management seriously lags behind current scientific understanding. Both the local traditions for curing pain and the substances used are presented in this book.
Download or read book Acute Pain Management written by Raymond S. Sinatra and published by Cambridge University Press. This book was released on 2009-04-27 with total page 729 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook provides an overview of pain management useful to specialists as well as non-specialists, surgeons, and nursing staff.
Download or read book The Oxford Handbook of the Neurobiology of Pain written by John N. Wood and published by Oxford University Press, USA. This book was released on 2020 with total page 939 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook is currently in development, with individual articles publishing online in advance of print publication. At this time, we cannot add information about unpublished articles in this handbook, however the table of contents will continue to grow as additional articles pass through the review process and are added to the site. Please note that the online publication date for this handbook is the date that the first article in the title was published online.
Download or read book Recognition and Alleviation of Pain and Distress in Laboratory Animals written by National Research Council and published by National Academies Press. This book was released on 1992-01-01 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clear guidelines on the proper care and use of laboratory animals are being sought by researchers and members of the many committees formed to oversee animal care at universities as well as the general public. This book provides a comprehensive overview of what we know about behavior, pain, and distress in laboratory animals. The volume explores: Stressors in the laboratory and the animal behaviors they cause, including in-depth discussions of the physiology of pain and distress and the animal's ecological relationship to the laboratory as an environment. A review of euthanasia of lab animals-exploring the decision, the methods, and the emotional effects on technicians. Also included is a highly practical, extensive listing, by species, of dosages and side effects of anesthetics, analgesics, and tranquilizers.
Download or read book Fundamentals of Anaesthesia written by Colin Pinnock and published by Cambridge University Press. This book was released on 2002-12 with total page 990 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of Fundamentals of Anaesthesia builds upon the success of the first edition, and encapsulates the modern practice of anaesthesia in a single volume. Written and edited by a team of expert contributors, it provides a comprehensive but easily readable account of all of the information required by the FRCA Primary examination candidate and has been expanded to include more detail on all topics and to include new topics now covered in the examination. As with the previous edition, presentation of information is clear and concise, with the use of lists, tables, summary boxes and line illustrations where necessary to highlight important information and aid the understanding of complex topics. Great care has been taken to ensure an unrivalled consistency of style and presentation throughout.
Download or read book The Management of Pain in Older People written by Patricia Schofield, PhD, RGN and published by John Wiley & Sons. This book was released on 2007-04-04 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will enable readers to understand the principles underpinning the management of pain which a particular emphasis upon the care of the older adult. The chapters will explore concepts that are recognised to be involved in the pain experience but each author will then add their own unique perspective by applying the principles to their specialist area of practice and the care of the older adult. It is structured to include the aims and outcomes of the chapter at the beginning so that readers can track their progress, and provides chapter outlines and further reading suggestions foir this unique topic area.
Download or read book Behavioral and Psychopharmacologic Pain Management written by Michael H. Ebert and published by Cambridge University Press. This book was released on 2010-11-25 with total page 507 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pain is the most common symptom bringing a patient to a physician's attention. Physicians training in pain medicine may originate from different disciplines and approach the field with varying backgrounds and experience. This book captures the theory and evidence-based practice of behavioral, psychotherapeutic and psychopharmacological treatments in modern pain medicine. The book's contributors span the fields of psychiatry, psychology, anesthesia, neurology, physical medicine and rehabilitation, and nursing. Thus the structure and content of the book convey the interdisciplinary approach that is the current standard for the successful practice of pain management. The book is designed to be used as a text for training fellowships in pain medicine, as well as graduate courses in psychology, nursing, and other health professions.
Download or read book Mechanisms and New Targets for the Treatment of Chronic Pain written by Milica S. Prostran and published by Frontiers Media SA. This book was released on 2020-12-03 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acute pain has a physiological protective role in preventing tissue damage. However, pain can become chronic due to a multitude of pathophysiological states, such as: trauma, inflammation, neural injury, viral infection, cancer, autoimmune diseases and vascular and metabolic disorders. These pathological states can trigger alterations of the pain pathways that can lead to hypersensitivity, and in such circumstances, pain loses its protective role and instead, becomes persistent and debilitating affecting seriously to the quality of life of patients. Chronic pain is one of the most important health problems worldwide. It has been estimated that 10% of adults are diagnosed with chronic pain each year. However, despite the high prevalence of chronic pain, its management is still no fully satisfactory probably due to the variety of chronic pain conditions with different etiologies (neuropathic, visceral and musculoskeletal pain), and because their pathophysiological mechanisms are only partially known. Therefore, there is a huge need for new effective therapies for the control and/or prevention of the different types of chronic pain. Chronic pain is associated with plastic changes in pain circuits of the peripheral and central nervous system, including changes in the expression of ion channels, neurotransmitters and receptors. In addition, there is growing consensus on non-neuronal mechanisms that can amplify or resolve chronic pain, and cells traditionally thought to act just as coordinators of the inflammatory response (such as immune and glial cells) are now accepted as real modulators of pain signaling. In this regard, animal models of persistent pain, such as models of neuropathic and visceral pain and models of arthritis, are helping to elucidate our understanding of the pathogenesis of chronic pain and make it possible to test experimental treatments.
Download or read book Immune Mechanisms of Pain and Analgesia written by Halina Machelska and published by Springer Science & Business Media. This book was released on 2003-01-31 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immune Mechanisms of Pain and Analgesia is the first volume to discuss a new concept of immune-neural interplays leading to pain or analgesia. It argues the classical view that pain and its control are restricted to the nervous system, offering a comprehensive overview of the emerging area of immune mechanisms in pain and its control. It challenges the traditional view that pain sensation or suppression is attributed exclusively to the nervous system and presents a critical analysis of this new concept. The book is written by an internationally recognized group of researchers and discusses complex and controversial issues such as cytokines and their pain-exacerbating but also analgesic effects, the production of opioids by immune cells, peripheral analgesic and anti-inflammatory actions of opioids, immunomodulatory effects of opiates, and immunosuppressive effects of pain.
