Download or read book Mathematical Modelling of Pulsatility in Neuroendocrine Systems written by David Bryan Barrass and published by . This book was released on 1993 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Pulsatility in Neuroendocrine Systems written by Jon E. Levine and published by Academic Press. This book was released on 2013-10-22 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pulsatility is now recognized as a nearly ubiquitous functional feature of neuroendocrine systems. This volume presents a comprehensive guide to the established and emerging technologies being used to study the perplexing phenomenon of pulsatility. Molecular, cellular, physiological, and mathematical approaches are described in detail. - In vitro methods for studying neuroendocrine pulsatility - In vivo sampling and recording procedures for monitoring pulsatility in several species - Improved quantitative and analytical methods for the study of hormone pulsatility
Download or read book Pulsatility in Neuroendocrine Sys written by Gareth Leng and published by Springer. This book was released on 1988 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Mechanisms and Biological Significance of Pulsatile Hormone Secretion written by Derek J. Chadwick and published by John Wiley & Sons. This book was released on 2003-10-31 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: This exciting book brings together an international and interdisciplinary group of experts to discuss the importance of pulsatile signalling in the induction of biological responses. Coverage includes the basic mechanisms involved in hormone pulsatility, the significance of pulsatility in normal and disease conditions, the relevance of circadian rhythms, changes with ageing, and detailed consideration of specific peptide hormone systems. This book includes contributions from professionals working in both basic and clinical research and reveals much new and exciting work in this area and promises new research directions.
Download or read book A Time for Metabolism and Hormones written by Paolo Sassone-Corsi and published by Springer. This book was released on 2016-04-04 with total page 141 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent years have seen spectacular advances in the field of circadian biology. These have attracted the interest of researchers in many fields, including endocrinology, neurosciences, cancer, and behavior. By integrating a circadian view within the fields of endocrinology and metabolism, researchers will be able to reveal many, yet-unsuspected aspects of how organisms cope with changes in the environment and subsequent control of homeostasis. This field is opening new avenues in our understanding of metabolism and endocrinology. A panel of the most distinguished investigators in the field gathered together to discuss the present state and the future of the field. The editors trust that this volume will be of use to those colleagues who will be picking up the challenge to unravel how the circadian clock can be targeted for the future development of specific pharmacological strategies toward a number of pathologies.
Download or read book The New Frontier of Network Physiology From Temporal Dynamics to the Synchronization and Principles of Integration in Networks of Physiological Systems written by Plamen Ch. Ivanov and published by Frontiers Media SA. This book was released on 2022-02-17 with total page 842 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Foundations and Tools for Neural Modeling written by Jose Mira and published by Springer Science & Business Media. This book was released on 1999-05-19 with total page 900 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes, together with its compagnion LNCS 1606, the refereed proceedings of the International Work-Conference on Artificial & Neural Networks, IWANN'99, held in Alicante, Spain in June 1999. The 91 revised papers presented were carefully reviewed & selected for inclusion in the book. This volume is devoted to applications of biologically inspired artificial neural networks in various engineering disciplines. The papers are organized in parts on artificial neural nets simulation & implementation, image processing & engineering applications.
Download or read book Stress and Mental Disorders written by Richard McCarty and published by Oxford University Press, USA. This book was released on 2020 with total page 673 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stress has been recognized as an important factor in the development or recurrence of various mental disorders, from major depressive disorder to bipolar disorder to anxiety disorders. Stressful stimuli also appear to exert their effects by acting upon individuals with susceptible genotypes. Over the past 50 years, animal models have been developed to study these dynamic interactions between stressful stimuli and genetically susceptible individuals during prenatal and postnatal development and into adulthood. Stress and Mental Disorders: Insights from Animal Models begins with a discussion of the history of psychiatric diagnosis and the recent goal of moving toward precision psychiatry, followed by a review of clinical research on connections between stressful stimuli and the development of psychiatric disorders. Chapters are also included on neuroendocrine, immune, and brain systems involved in responses to stress. Additional chapters focus on the development of animal models in psychiatry and the susceptibility of the developing organism to stressful stimuli. Subsequent chapters are devoted to animal models of specific stress-sensitive psychiatric disorders, including schizophrenia, autism spectrum disorders, bipolar disorder, anxiety disorders, depression, and post-traumatic stress disorder. These chapters also focus on identification of promising molecular targets for development of new drug therapies. The section concludes with a chapter on animal models of resilience to stress-induced behavioral alterations as a newer approach to understanding why some animals are susceptible to stress and others are resilient, even though they are essentially genetically identical. The final chapter discusses how these basic laboratory studies are providing promising leads for future breakthroughs in the diagnosis, treatment, and prevention of mental disorders.
Download or read book Neuroendocrinology written by and published by Elsevier. This book was released on 2010-05-24 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroendocrinology is a discipline which originated about 50 years ago as a branch of Endocrinology and that is now strictly linked to neuroscience. Volumes 181 and 182 of Progress in Brain Research provide a rapid view of the major points presently discussed at biological and clinical levels. The chapters have been written by top scientists who are directly involved in basic or clinical research and who use the most sophisticated biotechnological techniques. The volumes cover of the role of genetics in many endocrine-related events, like neuroendocrinological diseases and endocrine depenedent cancers (prostate, breast, etc,). Interesting information is also provided on possibile treatments of neurodegenerative brain diseases (e.g., Alzheimer and similar syndromes). • The best researchers in the field provide their conclusions in the context of the latest experimental results • Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered • Of great value for researchers and experts, but also for students as a background reference
Download or read book Foundations and Tools for Neural Modeling written by Jose Mira and published by Springer. This book was released on 2006-12-08 with total page 890 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes, together with its compagnion LNCS 1607, the refereed proceedings of the International Work-Conference on Artificial and Natural Neural Networks, IWANN'99, held in Alicante, Spain in June 1999. The 89 revised papers presented were carefully reviewed and selected for inclusion in the book. This volume is devoted to foundational issues of neural computation and tools for neural modeling. The papers are organized in parts on neural modeling: biophysical and structural models; plasticity phenomena: maturing, learning, and memory; and artificial intelligence and cognitive neuroscience.
Download or read book Quantitative Neuroendocrinology written by and published by Elsevier. This book was released on 1995-10-16 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this volume contemporary methods designed to provide insights into, mathematical structure for, and predictive inferences about neuroendocrine control mechanisms are presented. - Collates an array of contemporary techniques for analysis of neuroendocrine data - Discusses current problems in and solutions to neurohormone pulse analysis - Identifies relevant software available
Download or read book Biosimulation in Biomedical Research Health Care and Drug Development written by Erik Mosekilde and published by Springer Science & Business Media. This book was released on 2011-11-01 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biosimulation is an approach to biomedical research and the treatment of patients in which computer modeling goes hand in hand with experimental and clinical work. Constructed models are used to interpret experimental results and to accumulate information from experiment to experiment. This book explains the concepts used in the modeling of biological phenomena and goes on to present a series of well-documented models of the regulation of various genetic, cellular and physiological processes. The way how the use of computer models allows optimization of cancer treatment for individual patients is discussed and models of interacting nerve cells that can be used to design new treatments for patients with Parkinson's disease are explained. Furthermore this volume provides an overview on the use of models in industry, and presents the view of regulatory agencies on the topic.
Download or read book Handbook of Neuroendocrinology written by George Fink and published by Academic Press. This book was released on 2012 with total page 895 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroendocrinology underpins fundamental physiological, molecular, biological, and genetic principles such as the regulation of gene transcription and translation. This handbook highlights the experimental and technical foundations of each area's major concepts and principles.
Download or read book An Invitation to Biomathematics written by Raina Robeva and published by Academic Press. This book was released on 2007-08-28 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essential for all biology and biomathematics courses, this textbook provides students with a fresh perspective of quantitative techniques in biology in a field where virtually any advance in the life sciences requires a sophisticated mathematical approach. An Invitation to Biomathematics, expertly written by a team of experienced educators, offers students a solid understanding of solving biological problems with mathematical applications. This text succeeds in enabling students to truly experience advancements made in biology through mathematical models by containing computer-based hands-on laboratory projects with emphasis on model development, model validation, and model refinement. The supplementary work, Laboratory Manual of Biomathematics is available separately ISBN 0123740223, or as a set ISBN: 0123740290) - Provides a complete guide for development of quantification skills crucial for applying mathematical methods to biological problems - Includes well-known examples from across disciplines in the life sciences including modern biomedical research - Explains how to use data sets or dynamical processes to build mathematical models - Offers extensive illustrative materials - Written in clear and easy-to-follow language without assuming a background in math or biology - A laboratory manual is available for hands-on, computer-assisted projects based on material covered in the text
Download or read book Research Grants Index written by National Institutes of Health (U.S.). Division of Research Grants and published by . This book was released on 1966 with total page 1264 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biosimulation in Drug Development written by Martin Bertau and published by John Wiley & Sons. This book was released on 2008-09-08 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first comprehensive survey to cover all pharmaceutically relevant topics provides a comprehensive introduction to this novel and revolutionary tool, presenting both concepts and application examples of biosimulated cells, organs and organisms. Following an introduction to the role of biosimulation in drug development, the authors go on to discuss the simulation of cells and tissues, as well as simulating drug action and effect. A further section is devoted to simulating networks and populations, and the whole is rounded off by a look at the potential for biosimulation in industrial drug development and for regulatory decisions. Part of the authors are members of the BioSim Network of Excellence that encompasses more than 40 academic institutions, pharmaceutical companies and regulatory authorities dealing with drug development; other contributors come from industry, resulting in a cross-disciplinary expert reference.
Download or read book Bursting The Genesis Of Rhythm In The Nervous System written by Steve Coombes and published by World Scientific. This book was released on 2005-10-03 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurons in the brain communicate with each other by transmitting sequences of electrical spikes or action potentials. One of the major challenges in neuroscience is to understand the basic physiological mechanisms underlying the complex spatiotemporal patterns of spiking activity observed during normal brain functioning, and to determine the origins of pathological dynamical states such as epileptic seizures and Parkinsonian tremors. A second major challenge is to understand how the patterns of spiking activity provide a substrate for the encoding and transmission of information, that is, how do neurons compute with spikes? It is likely that an important element of both the dynamical and computational properties of neurons is that they can exhibit bursting, which is a relatively slow rhythmic alternation between an active phase of rapid spiking and a quiescent phase without spiking. This book provides a detailed overview of the current state-of-the-art in the mathematical and computational modeling of bursting, with contributions from many of the leading researchers in the field.
