Download or read book Interpretation of MS MS Mass Spectra of Drugs and Pesticides written by Wilfried M. A. Niessen and published by John Wiley & Sons. This book was released on 2017-01-30 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides comprehensive coverage of the interpretation of LC–MS–MS mass spectra of 1300 drugs and pesticides Provides a general discussion on the fragmentation of even-electron ions (protonated and deprotonated molecules) in both positive-ion and negative-ion modes This is the reference book for the interpretation of MS–MS mass spectra of small organic molecules Covers related therapeutic classes of compounds such as drugs for cardiovascular diseases, psychotropic compounds, drugs of abuse and designer drugs, antimicrobials, among many others Covers general fragmentation rule as well as specific fragmentation pathways for many chemical functional groups Gives an introduction to MS technology, mass spectral terminology, information contained in mass spectra, and to the identification strategies used for different types of unknowns
Download or read book Mass Spectra of Flavors and Fragrances of Natural and Synthetic Compounds written by Luigi Mondello and published by John Wiley & Sons. This book was released on 2015-03-09 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advanced Component Identification in Complex Mixtures Essential oils are mixtures consisting of monoterpene andsesquiterpene hydrocarbons, their oxygenated derivatives, andaliphatic oxygenated compounds. The difficulties that arise in theGC-MS peak identification of these complex samples is due to thefact that many terpenes have identical mass spectra. This is aconsequence of similarities both in the initial molecule, or in thefragmentation patterns and rearrangements after ionization. Hence,MS identification of these compounds should always be accompaniedby retention time information that may support the MS librarysearch results. This innovative MS library for natural and synthetic products(essential oils, perfumes, etc.) makes the identification ofunknown compounds in complex mixtures easier, faster and morereliable. The use of chromatographic information, such as LinearRetention Index (LRI), can be used to filter MS results, enablingthe more reliable peak assignment of components in complexmixtures. Mass spectra, relative to standard and well-known simple matrixcomponents, were obtained and recorded through GC-MSseparation/identification. Furthermore, traditional informationrelative to each component (CAS number, common name, CAS name,molecular weight, compound formula, chemical class) plus linearretention index values are entered. Flavors and Fragrances of Natural and Synthetic Compounds,3rd edition contains >3000 mass spectra, LRI retentiondata, calculated Kovats RI, and searchable chemical structures ofcompounds of interest for the flavors and fragrances industry.Prepared by the Prof. Luigi Mondello under rigorous measurementconditions, the mass spectral library contains compounds central toflavor and fragrance research. What's on the disc: 1. FFNSC 3 in MS Search (Agilent, Bruker, Leco, JEOL, , Agilent .L(Chemstation, MassHunter), PerkinElmer Turbomass, Waters MassLynx,ACD ND9, and Cromatoplus 2. 30-Day trial version of Cromatoplus software
Download or read book Direct Analysis in Real Time Mass Spectrometry written by Yiyang Dong and published by John Wiley & Sons. This book was released on 2018-04-09 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clear, comprehensive, and state of the art, the groundbreaking book on the emerging technology of direct analysis in real time mass spectrometry Written by a noted expert in the field, Direct Analysis in Real Time Mass Spectrometry offers a review of the background and the most recent developments in DART-MS. Invented in 2005, DART-MS offers a wide range of applications for solving numerous analytical problems in various environments, including food science, forensics, and clinical analysis. The text presents an introduction to the history of the technology and includes information on the theoretical background, for exampleon the ionization mechanism. Chapters on sampling and coupling to different types of mass spectrometers are followed by a comprehensive discussion of a broad range of applications. Unlike most other ionization methods, DART does not require laborious sample preparation, as ionization takes place directly on the sample surface. This makes the technique especially attractive for applications in forensics and food science. Comprehensive in scope, this vital text: -Sets the standard on an important and emerging ionization technique -Thoroughly discusses all the relevant aspects from instrumentation to applications -Helps in solving numerous analytical problems in various applications, for example food science, forensics, environmental and clinical analysis -Covers mechanisms, coupling to mass spectrometers, and includes information on challenges and disadvantages of the technique Academics, analytical chemists, pharmaceutical chemists, clinical chemists, forensic scientists, and others will find this illuminating text a must-have resource for understanding the most recent developments in the field.
Download or read book Designer Drugs written by Roy Gerona and published by Elsevier. This book was released on 2024-01-26 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Detection and Identification of Designer Drugs, the latest release in the Emerging Issues in Analytical Chemistry series, presents both an overview and a guide to techniques for anyone studying or engaging in designer drug analysis. Proliferation of the synthesis and use of designer drugs is a serious public health problem, with social, economic and legal implications. Whether abuse is studied at the population or individual level, researchers need both background and highly detailed technical information on specific drugs and drug classes in order to combat the proliferation and highly damaging consequences of these substances. Author Brian F. Thomas provides a comprehensive discussion that emphasizes the potential threat to society, presents the ongoing challenges confronting the various laboratory approaches to detection and identification of new chemical entities, and informs on the development of improved analytical solutions for use in legislation, law enforcement and treatment. Summarizes available literature and evaluates the strengths and weaknesses of analytical methods for detecting and identifying designer drugs Offers authoritative information from author Brian F. Thomas, an expert with over 30 years of experience in the field Directs the reader to sources of further reading at the conclusion of each chapter Emphasizes the potential threat to society Presents ongoing challenges confronting various laboratory approaches to detection and identification of new chemical entities
Download or read book Marine Cyanobacteria written by Loïc Charpy and published by Musee Oceanographique. This book was released on 1999 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Mass Spectra of Designer Drugs 2 Volume Set written by Peter Rösner and published by Wiley-VCH. This book was released on 2007-04-09 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on the authors' several decades of professional experience, this unique data collection is tailor-made for criminal and forensic investigators. It contains 8,800 mass spectrum records obtained from 4,379 compounds categorized as either designer or medicinal drugs, chemical warfare agents or explosives. It even covers those substances yet to be recorded by the police, but which are likely to be encountered by crime prevention and investigation authorities, in both the areas of illicit drugs and homeland security. The perfect companion for users of the Roesner database, this print edition features a wealth of additional data not contained in the online version, such as U.S. and U.N. legal category information, chromatographic data and mass spectrum quality and similarity indices.
Download or read book Frontiers of Bioanalytical Chemistry written by Frank-Michael Matysik and published by Springer. This book was released on 2013-01-27 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here, renowned researchers in bioanalysis present in-depth reviews of recent trends in the field. Coverage includes topics such as aptamers, bioelectroanalysis, nanoparticles, quantitative NMR, mass spectrometry, immunosensors and -assays, or chiral electromigration techniques. Originally published in the journal Bioanalytical Reviews, these outstanding contributions are now available in a hardcover print format. This volume benefits in particular those research groups and libraries that have chosen to have only electronic access to the journal. It also provides valuable content for all researchers in bioanalytical science.
Download or read book Holy Fire written by Bruce Sterling and published by Open Road Media. This book was released on 2020-08-11 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: Memory, morality, and immortality merge in this “haunting and lyrical triumph” from the bestselling author of Schismatrix Plus (Time). In the late twenty-first century, technology has lengthened lifespans far beyond what was once medically possible. Existence itself has become relatively easy—if boring. In this futuristic paradise, ninety-four-year-old Mia Ziemann longs for something different and undergoes a radical new treatment that restores both her body and mind to that of a twenty-year-old. After her dramatic transformation, Mia finds herself lost in an avant-garde world of passion, designer drugs, and creative expression . . . “Ideas—big ideas—lurk beneath Mia’s romp through Sterling’s delightfully imagined newly post-human Earth. Art, artifice, the pursuit of immortality, and youth and aging bounce around the story, the characters, and their conversations in imaginative, engaging fashion. . . . In the end, Holy Fire is one of the most interesting, imaginative, and subtly humorous—and relevant for it—novels the cyberpunk/post-human era has produced. . . . Holy Fire may very well be [Sterling’s] best work.” —Speculiction “An intellectual feat, it is also a treat for the spirit and the senses.” —Wired “A patented Sterling extra-special.” —Newsday “The future Sterling traces is plausible and provocative, particularly his consideration of several contrasting cultures, and of the disenfranchised who are unable to become ‘post-human.’ Those interested in serious speculative conversation set within a very strange near-future will find this much to their taste.” —Publishers Weekly
Download or read book Global Synthetic Drugs Assessment 2020 written by United Nations Publications and published by . This book was released on 2021-09-30 with total page 59 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Global Synthetic Drugs Assessment 2020 provides an analysis of the global synthetic drugs market in two parts.
Download or read book Current Analytical Trends in Drug Testing in Clinical and Forensic Toxicology written by Eugenia Gallardo and published by Frontiers Media SA. This book was released on 2021-06-24 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Chemoinformatics and Bioinformatics in the Pharmaceutical Sciences written by Navneet Sharma and published by Academic Press. This book was released on 2021-05-21 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemoinformatics and Bioinformatics in the Pharmaceutical Sciences brings together two very important fields in pharmaceutical sciences that have been mostly seen as diverging from each other: chemoinformatics and bioinformatics. As developing drugs is an expensive and lengthy process, technology can improve the cost, efficiency and speed at which new drugs can be discovered and tested. This book presents some of the growing advancements of technology in the field of drug development and how the computational approaches explained here can reduce the financial and experimental burden of the drug discovery process. This book will be useful to pharmaceutical science researchers and students who need basic knowledge of computational techniques relevant to their projects. Bioscientists, bioinformaticians, computational scientists, and other stakeholders from industry and academia will also find this book helpful. - Provides practical information on how to choose and use appropriate computational tools - Presents the wide, intersecting fields of chemo-bio-informatics in an easily-accessible format - Explores the fundamentals of the emerging field of chemoinformatics and bioinformatics
Download or read book Hair Analysis in Clinical and Forensic Toxicology written by Pascal Kintz and published by Academic Press. This book was released on 2015-06-25 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hair Analysis in Clinical and Forensic Toxicology is an essential reference for toxicologists working with, and researching, hair analysis. The text presents a review of the most up-to-date analytical methods in toxicological hair analysis, along with state-of-the-art developments in the areas of hair physiology, sampling, and pre-treatments, as well as discussions of fundamental issues, applications, and results interpretation. Topics addressed include the diagnosis of chronic excessive alcohol drinking by means of ethyl glucuronide (EtG) and fatty acid ethyl esters (FAEE), the early detection of new psychoactive substances, including designer drugs, the development of novel approaches to screening tests based on mass spectrometry, and the detection of prenatal exposure to psychoactive substances from the analysis of newborn hair. - Unites an international team of leading experts to provide an update on the cutting-edge advances in the toxicological analysis of hair - Demonstrates toxicological techniques relating to a variety of scenarios and exposure types - Ideal resource for the further study of the psychoactive substances, drug-facilitated crimes, ecotoxicology, analytical toxicology, occupational toxicology, toxicity testing, and forensic toxicology - Includes detailed instructions for the collection, preparation, and handling of hair, and how to best interpret results
Download or read book Using Mass Spectrometry for Drug Metabolism Studies written by Walter A. Korfmacher and published by CRC Press. This book was released on 2004-12-17 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mass spectrometry (MS) is fast becoming the premier tool for analyzing various drug metabolism samples in the early phases of drug discovery and research. Introducing the newer, more powerful MS equipment and exploring new applications for using them, this book provides a state-of-the-art look at this promising field. Using Mass Spectrometry
Download or read book The Role of Natural Products in Drug Discovery written by J. Mulzer and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 363 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural Products have been important sources of useful drugs from prehistoric times to the present. This book gives an overview about this field and provides important recent contributions to the discovery of new drugs generated by research on natural products. Total synthesis of natural products with interesting biological activities is paving the way for the preparation of new and improved analogs. The methods of combinatorial chemistry permit the selection of the best drug from a large number of candidates. Beyond synthesis and evaluation of organic molecules a number of new bioorganic methods are coming to the fore and will be discucced in this isue of the ERnst schering Research Foundation workshop proceedings.
Download or read book Urine Testing for Drugs of Abuse written by and published by . This book was released on 1986 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Advances in Forensic Applications of Mass Spectrometry written by Jehuda Yinon and published by CRC Press. This book was released on 2003-12-29 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent developments in analytical instrumentation have had an enormous influence on forensic analysis. The mass spectrometer is now an integral part of every forensic laboratory, resulting in greater analytical accuracy, more reliable identification, and lower detection limits. As the instrumental method of choice among forensic analysts, the mass
Download or read book Mass Spectra of Designer Drugs 2022 written by Peter Rösner and published by . This book was released on 2022 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
