Download or read book Manganese in Metabolism and Enzyme Function written by Vern L. Schramm and published by Elsevier. This book was released on 2012-12-02 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: Manganese in Metabolism and Enzyme Function provides an understanding of the various biological roles of the trace levels of manganese found in mammalian systems. This text discusses the nutritional aspects of manganese in mammals. This book is organized into three sections encompassing 19 chapters. Section I discusses the effects of manganese deficiency, including abnormal pancreatic action and reduced pancreatic manganese in humans and laboratory animals. This text considers the criteria for adding manganese to infant formulas that are commercially available. Section II explores the effects of Mn(II) in protein kinases, protein phosphatases, and other enzymes. The reader is introduced to the electron paramagnetic resonance spectroscopic probes of manganese function. Other chapters discuss the extrinsic tag technique used to study the bioavailability of trace elements, such as iron and zinc. Finally, Section III examines the biophysical, biochemical, and physiological properties and uses of manganese. Nutritionists, toxicologists, scientists, and researchers will find this book extremely useful.
Download or read book Manganese Redox Enzymes written by Vincent L. Pecoraro and published by Wiley-VCH. This book was released on 1992 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Metal Ions in Biological Systems written by Helmut Sigel and published by CRC Press. This book was released on 2000-01-27 with total page 814 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Highlights the availability of magnesium to organisms, its uptake and transport in microorganisms and plants as well as its role in health and disease of animals and humans including its toxicology."
Download or read book Metal Ions in Biological Systems written by Helmut Sigel and published by CRC Press. This book was released on 2000-01-27 with total page 810 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Highlights the availability of magnesium to organisms, its uptake and transport in microorganisms and plants as well as its role in health and disease of animals and humans including its toxicology."
Download or read book Manganese in Health and Disease written by Lucio G Costa and published by Royal Society of Chemistry. This book was released on 2014-11-27 with total page 655 pages. Available in PDF, EPUB and Kindle. Book excerpt: Manganese in the diet is nutritionally essential for normal physiologic functioning. However, excessive exposure to manganese has been associated with developmental, neurodegenerative and other disorders. The book comprehensively covers the toxicology of manganese. Leading investigators provide perspectives from toxicology, neuroscience, nutrition, molecular biology and risk assessment disciplines and chapters cover the toxicokinetics, toxicodynamic interactions and health effects of manganese, as well as its potential role in neurodegenerative diseases. A large section devoted to health effects presents the latest research that associates manganese exposure to potential human diseases. Any scientists, health professional or regulator involved with metal exposure and toxicology should find this volume essential reading. Students and researchers in neurotoxicology will also find this book a useful reference.
Download or read book Essential Metals in Medicine Therapeutic Use and Toxicity of Metal Ions in the Clinic written by Peggy L. Carver and published by Walter de Gruyter GmbH & Co KG. This book was released on 2019-01-14 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 19, entitled Essential Metals in Medicine: Therapeutic Use and Toxicity of Metal Ions in the Clinic of the series Metal Ions in Life Sciences centers on the role of metal ions in clinical medicine. Metal ions are tightly regulated in human health: while essential to life, they can be toxic as well. Following an introductory chapter briefly discussing several important metal-related drugs and diseases and a chapter about drug development, the focus is fi rst on iron: its essentiality for pathogens and humans as well as its toxicity. Chelation therapy is addressed in the context of thalassemia, its relationship to neurodegenerative diseases and also the risks connected with iron administration are pointed out. A subject of intense debate is the essentiality of chromium and vanadium. For example, chromium(III) compounds are taken as a nutritional supplement by athletes and bodybuilders; in contrast, chromate, Cr(VI), is toxic and a carcinogen for humans. The benefi cial and toxic effects of manganese, cobalt, and copper on humans are discussed. The need for antiparasitic agents is emphasized as well as the clinical aspects of metal-containing antidotes for cyanide poisoning. In addition to the essential and possibly essential ones, also other metal ions play important roles in human health, causing harm (like the metalloid arsenic, lead or cadmium) or being used in diagnosis or treatment of human diseases, like gadolinium, gallium, lithium, gold, silver or platinum. The impact of this vibrant research area on metals in the clinic is provided in 14 stimulating chapters, written by internationally recognized experts from the Americas, Europe and China, and is manifested by approximately 2000 references, and about 90 illustrations and tables. Essential Metals in Medicine: Therapeutic Use and Toxicity of Metal Ions in the Clinic is an essential resource for scientists working in the wide range from pharmacology, enzymology, material sciences, analytical, organic, and inorganic biochemistry all the way through to medicine ... not forgetting that it also provides excellent information for teaching.
Download or read book Nutritional Bioavailability of Iron written by Constance Kies and published by . This book was released on 1982 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract: Research results concerning aspects of iron (Fe) bioavailability from various foods and interactions of Fe with other nutrients are reported by experts for nutritionists and food and agricultural chemists. Several areas address the determination of available Fe in foods, changes in Fe availability caused by food processing, physiochemical food properties affecting Fe chemstry, and food additives that either enhance or inhibit Fe intake. Therelationship of ascorbic acid in aiding Fe absorption is discussed, as is the inhibitory action of dietary fiber. Twoimportant human nutrition aspects cover Fe availability in human milk, and the differences in Fe utilization between vegetarians and omnivores. When careful choice is made of food combinations, food additives, and proper processing methods, humans can utilize a greater portion of the Fe in low-energy foods. (wz).
Download or read book Modeling of Manganese Redox Enzymes written by Bijan Ahvazi and published by . This book was released on 1995 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Manganese written by Heather Hasan and published by The Rosen Publishing Group, Inc. This book was released on 2008-01-15 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explains the characteristics of manganese, where it is found, how it is used by humans, and its relationship to other elements found in the periodic table.
Download or read book Models of Iron and Manganese containing Enzymes written by Anne Nielsen and published by . This book was released on 2010 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Manganese in Health and Disease written by Lucio G Costa and published by Royal Society of Chemistry. This book was released on 2014-12-05 with total page 654 pages. Available in PDF, EPUB and Kindle. Book excerpt: Manganese in the diet is nutritionally essential for normal physiologic functioning. However, excessive exposure to manganese has been associated with developmental, neurodegenerative and other disorders. The book comprehensively covers the toxicology of manganese. Leading investigators provide perspectives from toxicology, neuroscience, nutrition, molecular biology and risk assessment disciplines and chapters cover the toxicokinetics, toxicodynamic interactions and health effects of manganese, as well as its potential role in neurodegenerative diseases. A large section devoted to health effects presents the latest research that associates manganese exposure to potential human diseases. Any scientists, health professional or regulator involved with metal exposure and toxicology should find this volume essential reading. Students and researchers in neurotoxicology will also find this book a useful reference.
Download or read book Encyclopedia of Metalloproteins written by Robert H. Kretsinger and published by Springer. This book was released on 2013-05-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In biochemistry, a metalloprotein is a generic term for a protein that contains a metal cofactor. The metal may be an isolated ion or may be coordinated with a nonprotein organic compound, such as the porphyrin found in hemoproteins. In some cases, the metal is co-coordinated with a side chain of the protein and an inorganic nonmetallic ion. This kind of protein-metal-nonmetal structure is seen in iron-sulfur clusters Metalloproteins deals with all aspects related to the intracellular and extracellular metal-binding proteins, including their structures, properties and functions. The biological roles of metal cations and metal-binding proteins are endless. They are involved in all crucial cellular activities. Many pathological conditions are related to the problematic metal metabolism. Research in metalloprotein-related topics is therefore rapidly growing, and different aspects of metal-binding proteins progressively enter curricula at Universities and even at the High School level on occasion. However, no key resource providing basic, but comprehensible knowledge on this rapidly expanding field exists. The Encyclopedia of Metalloproteins aims to bridge this gap, and will attempt to cover various aspects of metalloprotein/metalloproteomics and will deal with the different issues related to the intracellular and extracellular metal-binding proteins, including their structures, properties and functions. The goal is to cover exhaustively all catalytically and biologically crucial metal ions and to find at least one interacting protein for other metal ions. The Encyclopedia of Metalloproteins will provide a key resource for advanced undergraduate and graduate students, researchers, instructors, and professors interested in protein science, biochemistry, cell biology, and genetics.
Download or read book Manganese in Soils and Plants written by R.D. Graham and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sixty years ago at the Waite Agricultural Research Institute, G. Samuel, a plant pathologist, and C. S. Piper, a chemist, published their conclusion that the cause of roadside take-all, a disease of oats, was manganese deficiency. This report, together with the concurrent and independent studies of W. M. Carne in Western Australia were the first records of manganese deficiency in Australia and came only six years after McHargue's paper which is generally accepted as the final proof of the essentiality of this element. There must have been a few doubts for some people at the time, however, as the CAB publication, 'The Minor Elements of the Soil' (1940) expressed the view that further evidence to this effect was provided by Samuel and Piper. Their historic contributions are recognised by the International Symposium on Manganese in Soils and Plants as it meets on the site of their early labours to celebrate the 60th anniversary. This year Australians also acknowledge 200 years of European settlement in this country and so the Symposium is both a Bicentennial and a diamond jubilee event which recognises the impact of trace elements on agricultural development in Australia. In a broader sense, a symposium such as this celebrates, as it reviews, the efforts of all who over the ages have contributed to our knowledge of manganese in soils and plants.
Download or read book Handbook of Minerals as Nutritional Supplements written by Robert A. DiSilvestro and published by CRC Press. This book was released on 2004-09-29 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mineral supplements are receiving a great deal of attention and experiencing a tremendous period of growth. Despite their popularity, questions continue to arise regarding the research behind their claims, the efficacy of different forms, and their overall safety. It is critical for the health care community and the general public to have an unbias
Download or read book Metal Carbon Bonds in Enzymes and Cofactors written by Astrid Sigel and published by Royal Society of Chemistry. This book was released on 2009-03-09 with total page 539 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chapter 10 focuses on the interaction of CN- with enzymes containing vanadium, manganese, non-heme iron, and zinc, and the inhibiting properties of this ligand, allowing its use as a probe. The reaction mechanism of the molybdenum hydroxylase xanthine oxidoreductase is revisited in Chapter 11; previously a molybdenum-carbon bond was postulated but now proof is presented against its formation. The terminating Chapter 12 reviews briefly the most popular computational approaches employed in theoretical studies of bioorganometallic species by providing detailed examples.
Download or read book Manganese in Health and Disease written by Dorothy Klimis-Zacas and published by CRC Press. This book was released on 1993-11-23 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: Manganese in Health and Disease discusses recent advances of the role of manganese on different human pathologies. The book presents research discussing the possible role of manganese in the development of some degenerative diseases such as diabetes, osteoporosis, and atherosclerosis. The role of manganese in individuals with epilepsy and congenital malformations is also discussed. This comprehensive book will interest basic researchers and clinicians including research scientists, physicians, nutritionists, dietitians, nurses, and educators.
Download or read book Toxicological Profile for Manganese written by and published by . This book was released on 1997 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt:
