Download or read book Managing Health in the Genomic Era written by Vincent Henrich and published by Academic Press. This book was released on 2020-06-27 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Managing Health in the Genomic Era: A Guide to Family Health History and Disease Risk, Drs. Vincent C. Henrich, Lori A. Orlando, and Brian H. Shirts discuss the practical considerations surrounding the use of genomic and genetic tests to manage patient health, to provide adult disease risk assessment, to improve diagnosis, and to support effective interventions and treatment. In 10 chapters, evidence-based information and case studies are described and examine the central place of family health history (FHH) in genomic medicine, tools and strategies for compiling and analyzing family health history, how to identify existing and novel genetic markers, how to identify lineage specific (or rare) variants within families, and how to find effective interventions based on genetic testing results and FHH. Factors that influence clinical practice, including gene-environment interactions, FHH social networking, direct to consumer (DTC) genetic testing and data sharing, algorithms for analyzing genetic data, and patient counseling are discussed from the standpoint of clinical practice. Here, frontline healthcare providers will discover succinct commentary and key examples to assist with their local needs. Relevant principles of genetic biology and inheritance are explored and guidance on available support networks and online resources is also provided. - 2021 PROSE Awards - Winner: Category: Clinical Medicine: Association of American Publishers - Presents a practical, accessible resource for primary care providers, allied health professionals, pharmacologists, public health professionals, students and clinical researchers - Addresses genetic and genomic approaches in managing patient health, conducting and analyzing family health histories, and assessing adult disease risk - Features an expert author team with direct experience integrating genetics and genomics in primary care and family medicine settings - Examines the attributes and limitations of family health history, genetic testing, and genomic testing in clinical practice - Includes detailed explanations following practice-based examples
Download or read book Health in the Genomic Era written by PHG Foundation and published by . This book was released on 2014 with total page 2 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Nursing Care in the Genomic Era written by Jean F. Jenkins and published by Jones & Bartlett Learning. This book was released on 2005 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Increasingly, genomic-based approaches and resources are redefining our categorization of disease, leading to new approaches to prevention and therapy. As nurses traditionally practice patient-oriented care, they will undoubtedly play a key role in both developing and applying the aspects of genomic health care. Nursing Care in the Genomic Era: A Case Based Approach is designed to provide nurses with up-to-date and accessible information on this powerful new approach to understanding, preventing, and treating disease.
Download or read book Medical and Health Genomics written by Dhavendra Kumar and published by Academic Press. This book was released on 2016-06-04 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical and Health Genomics provides concise and evidence-based technical and practical information on the applied and translational aspects of genome sciences and the technologies related to non-clinical medicine and public health. Coverage is based on evolving paradigms of genomic medicine—in particular, the relation to public and population health genomics now being rapidly incorporated in health management and administration, with further implications for clinical population and disease management. - Provides extensive coverage of the emergent field of health genomics and its huge relevance to healthcare management - Presents user-friendly language accompanied by explanatory diagrams, figures, and many references for further study - Covers the applied, but non-clinical, sciences across disease discovery, genetic analysis, genetic screening, and prevention and management - Details the impact of clinical genomics across a diverse array of public and community health issues, and within a variety of global healthcare systems
Download or read book Plant Disease Management in the Post Genomic Era from Functional Genomics to Genome Editing written by Sabrina Sarrocco and published by . This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Crop plants are continuously under attack by pathogens, both during pre and post-harvest stages, often causing economically important food losses. Chemical treatments can pose a serious treat to human health and the environment. Furthermore, there is an increasing market, especially in OECD countries for organic produce, for which most pesticides and inorganic fertilisers are unacceptable. There is therefore a pressing need to develop more effective, sustainable and environmentally friendly tools for disease control. The use of beneficial microorganisms for the control of plant pathogens is very attractive, and the availability of novel molecular techniques and a plethora of genomic information open unexplored avenues for plant protection approaches. Genome-enabled integration of research became a major strategy in the era of the 2000's (the post-genomic era) and set the basis for a different way to understand interactions in plant-pathogen-beneficial microorganisms systems. In recent decades we have moved from the sequencing of single genomes, to the comparison of different genomes, their expression (from single organism to communities) and, more recently, we can apply novel techniques to edit a genome in a precise manner. Together with the complete sequencing of plant genomes, the genome sequences of plant pathogens as well as that of some beneficial organisms (bacteria, fungi, viruses), and the furnished information on their virulence, gave support to relatively new strategies such as transcriptome, proteome, metabolome and secretome analysis. Analyses of avirulence and resistance genes, their products and the cross-talking mechanisms, as well as proteins and metabolites - at an "omics" level - in highly performing beneficial microorganisms/pathogens interactions, represents a major contribution to plant protection, providing information at an unprecedented level of resolution. While single genomes are explored to infer the range of biological activities accomplished by a single organism or species, and comparative genomics allows evaluating the diversity and evolution of biochemical pathways adopted by individual species to perform a common function, information is being obtained about processes carried out by a diverse set of organisms interacting with each other. Environmental genomics, popularized by the metagenome concept, can generate billions of DNA sequences from a given environment furnishing a comparative assessment of a community in situ. Metagenomics (sequence-based approaches applied across genomes in an environment) provides information about functional capabilities and responses of organism (plant, pathogen and beneficial agent) assemblages in different niches, giving a different perspective in the management of plant diseases at a multitrophic level. Advances in functional genomics and genome editing approaches have recently provided new tools to manage the plant-pathogen-beneficial microorganism system, for preventing or controlling disease. The use of RNA-based technologies is extremely appealing, and these include artificial micro-RNA and transacting small interfering RNA, which are currently being used for generating plant virus-resistant plants, thus fostering plant virus control researches. Finally, targeted genome editing strategies - exemplified by, but not limited to, the CRISPR-Cas technique - are among the most modern ways for inducing targeted deletions, insertions and precise changes in the genome of host plants or pathogens, as well as in the genomes of beneficial microorganisms. The aim of the present Research Topic is to give an exhaustive and up to date overview of examples of genomic techniques (genome sequencing, genome comparison, transcriptomics, metagenomics, RNA based technologies and genome editing strategies) applied to plants, pathogens or beneficial microorganisms to promote the exploitation of these modern tools as a new frontier in plant disease management.
Download or read book Microbial Diversity in the Genomic Era written by Surajit Das and published by Academic Press. This book was released on 2018-09-20 with total page 715 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbial Diversity in the Genomic Era presents insights on the techniques used for microbial taxonomy and phylogeny, along with their applications and respective pros and cons. Though many advanced techniques for the identification of any unknown bacterium are available in the genomics era, a far fewer number of the total microbial species have been discovered and identified to date. The assessment of microbial taxonomy and biosystematics techniques discovered and practiced in the current genomics era with suitable recommendations is the prime focus of this book. - Discusses the techniques used for microbial taxonomy and phylogeny with their applications and respective pros and cons - Reviews the evolving field of bacterial typing and the genomic technologies that enable comparative analysis of multiple genomes and the metagenomes of complex microbial environments - Provides a uniform, standard methodology for species designation
Download or read book Renaissance Of Sickle Cell Disease Research In The Genome Era written by Betty Pace and published by World Scientific. This book was released on 2007-01-24 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Human Genome Project has spawned a Renaissance of research faced with the daunting expectation of personalized medicine for individuals with sickle cell disease in the Genome Era. This book offers a comprehensive and timeless account of emerging concepts in clinical and basic science research, and community concerns of health disparity to educate professionals, students and the general public about meeting this challenging expectation. Contributions from physicians, research scientists, scientific administrators and community workers make Renaissance of Sickle Cell Disease Research in the Genome Era unique among the catalogue of books on this genetic disorder.Part 1 offers detailed review of the National Heart Lung and Blood Institute's leadership role in funding sickle cell research, as well as developing progressive research initiatives and the predicted impact of the Human Genome Project. Part 2 gives an account of several clinical research perspectives based on the Cooperative Study of Sickle Cell Disease. These include recommendations for newborn screening, pain management, stroke, transfusion therapy and pediatric and adult healthcare. Part 3 offers novel insights into basic science research progress and the impact of the Human Genome Project on the direction of hemoglobinopathy research, including hemoglobin switching, bone marrow transplantation and gene therapy. Part 4 engages the reader in a culture-based discussion of the stigma attached to sickle cell disease in the African American community and the apprehensions about genetic research in this community. It concludes with a global perspective on sickle cell disease from African, European and American experiences. For readers seeking a definitive account of sickle cell disease appropriate for students, researchers and community workers, this collaborative effort is an ideal textbook./a
Download or read book Provider Led Population Health Management written by Richard Hodach and published by John Wiley & Sons. This book was released on 2016-09-15 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provider-Led Population Health Management: Key Healthcare Strategies in the Cognitive Era, Second Edition draws connections among the new care-delivery models, the components of population health management, and the types of health IT that are required to support those components. The key concept that ties all of this together is that PHM requires a high degree of automation to reach everyone in a population, engage those patients in self-care, and maximize the chance that they will receive the proper preventive, chronic, and acute care. While this book is intended for healthcare executives and policy experts, anyone who is interested in health care can learn something from its exploration of the major issues that are stirring health care today. In the end, the momentous changes going on in health care will affect us all.
Download or read book Preventive and Predictive Genetics Towards Personalised Medicine written by Godfrey Grech and published by Springer. This book was released on 2016-10-17 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmacogenomics supports personalized medicine by translating genome-based knowledge into clinical practice, offering enhanced benefit for patients and health-care systems at large. Current routine practice for diagnosing and treating patients is conducted by correlating parameters such as age, gender and weight with risks and expected treatment outcomes. In the new era of personalized medicine the healthcare provider is equipped with improved ability to prevent, diagnose, treat and predict outcomes on the basis of complex information sources, including genetic and genomic data. Targeted therapy and reliable prediction of expected outcomes offer patients access to better healthcare management, by way of identifying the therapies effective for the relevant patient group, avoiding prescription of unnecessary treatment and reducing the likelihood of developing adverse drug reactions.
Download or read book Plant Biotechnology Progress in Genomic Era written by S. M. Paul Khurana and published by Springer Nature. This book was released on 2019-11-14 with total page 670 pages. Available in PDF, EPUB and Kindle. Book excerpt: Refinement in sequencing technologies and potential of genomic research resulted in meteoric growth of biological information such as sequences of DNA, RNA and protein requiring databases for efficient storage, management and retrieval of the biological information. Also, computational algorithms for analysis of these colossal data became a vital aspect of biological sciences. The work aims to show the process of turning bioscience innovation into companies and products, covering the basic science, the translation of science into technology. Due to rapid developments, there seems to be no basic difference between the pharmaceutical industry and the biotechnological industry. However, approved products in the pipeline and renewed public confidence make it one of the most promising areas of economic growth in the near future. India offers a huge market for the products as well as cheap manufacturing base for export. The book is a sincere work of compilation of new and recent advances in the topic of concern through various innovative researches and scientific opinion therefrom. The book is dedicated to the readers who will definitely find it interesting and knowledgeable in carrying out their respective researches in different aspects of applied microbiology and biotechnology.
Download or read book Plant Disease Management in the Post Genomic Era From Functional Genomics to Genome Editing written by Sabrina Sarrocco and published by Frontiers Media SA. This book was released on 2020-03-16 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Handbook of Pharmaceutical Biotechnology written by Shayne Cox Gad and published by John Wiley & Sons. This book was released on 2007-05-23 with total page 1681 pages. Available in PDF, EPUB and Kindle. Book excerpt: A practical overview of a full rangeof approaches to discovering, selecting, and producing biotechnology-derived drugs The Handbook of Pharmaceutical Biotechnology helps pharmaceutical scientists develop biotech drugs through a comprehensive framework that spans the process from discovery, development, and manufacturing through validation and registration. With chapters written by leading practitioners in their specialty areas, this reference: Provides an overview of biotechnology used in the drug development process Covers extensive applications, plus regulations and validation methods Features fifty chapters covering all the major approaches to the challenge of identifying, producing, and formulating new biologically derived therapeutics With its unparalleled breadth of topics and approaches, this handbook is a core reference for pharmaceutical scientists, including development researchers, toxicologists, biochemists, molecular biologists, cell biologists, immunologists, and formulation chemists. It is also a great resource for quality assurance/assessment/control managers, biotechnology technicians, and others in the biotech industry.
Download or read book Principles of Gender Specific Medicine written by Marianne Legato J and published by Academic Press. This book was released on 2017-05-15 with total page 794 pages. Available in PDF, EPUB and Kindle. Book excerpt: The announcement that we had decoded the human genome in 2000 ushered in a new and unique era in biomedical research and clinical medicine. This Third Edition of Principles of Gender-Specific Medicine focuses, as in the past two editions, on the essentials of sexual dimorphism in human physiology and pathophysiology, but emphasizes the latest information about molecular biology and genomic science in a variety of disciplines. Thus, this edition is a departure from the previous two; the editor solicited individual manuscripts from innovative scientists in a variety of fields rather than the traditional arrangement of sections devoted to the various subspecialties of medicine edited by section chiefs. Wherever it was available, these authors incorporated the latest information about the impact of the genome and the elements that modify its expression on human physiology and illness. All chapters progress translationally from basic science to the clinical applications of gender-specific therapy and suggest the most important topics for future investigation. This book is essential reading for all biomedical investigators and medical educators involved in gender-specific medicine. It will also be useful for primary care practitioners who need information about the importance of sex and gender in the prevention, diagnosis and treatment of illness. Winner of the 2018 PROSE Award in Clinical Medicine from the Association of American Publishers! 2018 PROSE Awards - Winner, Award for Clinical Medicine: Association of American Publishers Outlines sex-specific differences in normal human function and explains the impact of age, hormones, and environment on the incidence and outcome of illness Reflects the latest information about the molecular basis of the sexual dimorphism in human physiology and the experience of disease Reviews the implications of our ever-improving ability to describe the genetic basis of vulnerability to disease and our capacity to alter the genome itself Illustrates the importance of new NIH guidelines that urge the inclusion of sex as a variable in research protocols
Download or read book Digital Twin for Healthcare written by Abdulmotaleb El Saddik and published by Elsevier. This book was released on 2022-11-21 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: Digital Twins for Healthcare: Design, Challenges and Solutions establishes the state-of-art in the specification, design, creation, deployment and exploitation of digital twins' technologies for healthcare and wellbeing. A digital twin is a digital replication of a living or non-living physical entity. When data is transmitted seamlessly, it bridges the physical and virtual worlds, thus allowing the virtual entity to exist simultaneously with the physical entity. A digital twin facilitates the means to understand, monitor, and optimize the functions of the physical entity and provide continuous feedback. It can be used to improve citizens' quality of life and wellbeing in smart cities and the virtualization of industrial processes. Presents the fundamentals of digital twin technology in healthcare Facilitates new approaches for healthcare industry Explores different use cases of digital twins in healthcare
Download or read book The DNA Mystique written by Dorothy Nelkin and published by University of Michigan Press. This book was released on 2010-02-01 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The DNA Mystique is a wake-up call to all who would dismiss America's love affair with 'the gene' as a merely eccentric obsession." --In These Times "Nelkin and Lindee are to be warmly congratulated for opening up this intriguing field [of genetics in popular culture] to further study." --Nature The DNA Mystique suggests that the gene in popular culture draws on scientific ideas but is not constrained by the technical definition of the gene as a section of DNA that codes for a protein. In highlighting DNA as it appears in soap operas, comic books, advertising, and other expressions of mass culture, the authors propose that these domains provide critical insights into science itself. With a new introduction and conclusion, this edition will continue to be an engaging, accessible, and provocative text for the sociology, anthropology, and bioethics classroom, as well as stimulating reading for those generally interested in science and culture.
Download or read book Legionellosis Diagnosis and Control in the Genomic Era written by Rachel E Gibbs and published by . This book was released on 2020-07-09 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Bioinformatics in the Post genomic Era written by Jeffrey Augen and published by Addison-Wesley Professional. This book was released on 2005 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive treatment of the role of bioinformatics in the emerging world of molecular medicine, for anyone involved in this new field
