Download or read book Managing Discovery in the Life Sciences written by Philip A. Rea and published by Cambridge University Press. This book was released on 2018-02 with total page 557 pages. Available in PDF, EPUB and Kindle. Book excerpt: Addresses in roughly equal measure the science and management behind several recent marketable biomedical innovations.

Download or read book E discovery Creating and Managing an Enterprisewide Program written by Karen A. Schuler and published by Syngress. This book was released on 2011-04-18 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the hottest topics in computer forensics today, electronic discovery (e-discovery) is the process by which parties involved in litigation respond to requests to produce electronically stored information (ESI). According to the 2007 Socha-Gelbmann Electronic Discovery Survey, it is now a $2 billion industry, a 60% increase from 2004, projected to double by 2009. The core reason for the explosion of e-discovery is sheer volume; evidence is digital and 75% of modern day lawsuits entail e-discovery.A recent survey reports that U.S. companies face an average of 305 pending lawsuits internationally. For large U.S. companies ($1 billion or more in revenue)that number has soared to 556 on average, with an average of 50 new disputes emerging each year for nearly half of them. To properly manage the role of digital information in an investigative or legal setting, an enterprise--whether it is a Fortune 500 company, a small accounting firm or a vast government agency--must develop an effective electronic discovery program. Since the amendments to the Federal Rules of Civil Procedure, which took effect in December 2006, it is even more vital that the lifecycle of electronically stored information be understood and properly managed to avoid risks and costly mistakes. This books holds the keys to success for systems administrators, information security and other IT department personnel who are charged with aiding the e-discovery process. - Comprehensive resource for corporate technologists, records managers, consultants, and legal team members to the e-discovery process, with information unavailable anywhere else - Offers a detailed understanding of key industry trends, especially the Federal Rules of Civil Procedure, that are driving the adoption of e-discovery programs - Includes vital project management metrics to help monitor workflow, gauge costs and speed the process

Download or read book Open Source Software in Life Science Research written by Lee Harland and published by Elsevier. This book was released on 2012-10-31 with total page 583 pages. Available in PDF, EPUB and Kindle. Book excerpt: The free/open source approach has grown from a minor activity to become a significant producer of robust, task-orientated software for a wide variety of situations and applications. To life science informatics groups, these systems present an appealing proposition - high quality software at a very attractive price. Open source software in life science research considers how industry and applied research groups have embraced these resources, discussing practical implementations that address real-world business problems.The book is divided into four parts. Part one looks at laboratory data management and chemical informatics, covering software such as Bioclipse, OpenTox, ImageJ and KNIME. In part two, the focus turns to genomics and bioinformatics tools, with chapters examining GenomicsTools and EBI Atlas software, as well as the practicalities of setting up an 'omics' platform and managing large volumes of data. Chapters in part three examine information and knowledge management, covering a range of topics including software for web-based collaboration, open source search and visualisation technologies for scientific business applications, and specific software such as DesignTracker and Utopia Documents. Part four looks at semantic technologies such as Semantic MediaWiki, TripleMap and Chem2Bio2RDF, before part five examines clinical analytics, and validation and regulatory compliance of free/open source software. Finally, the book concludes by looking at future perspectives and the economics and free/open source software in industry. - Discusses a broad range of applications from a variety of sectors - Provides a unique perspective on work normally performed behind closed doors - Highlights the criteria used to compare and assess different approaches to solving problems

Download or read book Biological Collections written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2021-01-29 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological collections are a critical part of the nation's science and innovation infrastructure and a fundamental resource for understanding the natural world. Biological collections underpin basic science discoveries as well as deepen our understanding of many challenges such as global change, biodiversity loss, sustainable food production, ecosystem conservation, and improving human health and security. They are important resources for education, both in formal training for the science and technology workforce, and in informal learning through schools, citizen science programs, and adult learning. However, the sustainability of biological collections is under threat. Without enhanced strategic leadership and investments in their infrastructure and growth many biological collections could be lost. Biological Collections: Ensuring Critical Research and Education for the 21st Century recommends approaches for biological collections to develop long-term financial sustainability, advance digitization, recruit and support a diverse workforce, and upgrade and maintain a robust physical infrastructure in order to continue serving science and society. The aim of the report is to stimulate a national discussion regarding the goals and strategies needed to ensure that U.S. biological collections not only thrive but continue to grow throughout the 21st century and beyond.

Download or read book Managing Scientific Information and Research Data written by Svetla Baykoucheva and published by Chandos Publishing. This book was released on 2015-07-14 with total page 163 pages. Available in PDF, EPUB and Kindle. Book excerpt: Innovative technologies are changing the way research is performed, preserved, and communicated. Managing Scientific Information and Research Data explores how these technologies are used and provides detailed analysis of the approaches and tools developed to manage scientific information and data. Following an introduction, the book is then divided into 15 chapters discussing the changes in scientific communication; new models of publishing and peer review; ethics in scientific communication; preservation of data; discovery tools; discipline-specific practices of researchers for gathering and using scientific information; academic social networks; bibliographic management tools; information literacy and the information needs of students and researchers; the involvement of academic libraries in eScience and the new opportunities it presents to librarians; and interviews with experts in scientific information and publishing. - Promotes innovative technologies for creating, sharing and managing scientific content - Presents new models of scientific publishing, peer review, and dissemination of information - Serves as a practical guide for researchers, students, and librarians on how to discover, filter, and manage scientific information - Advocates for the adoption of unique author identifiers such as ORCID and ResearcherID - Looks into new tools that make scientific information easy to discover and manage - Shows what eScience is and why it is becoming a priority for academic libraries - Demonstrates how Electronic Laboratory Notebooks can be used to record, store, share, and manage research data - Shows how social media and the new area of Altmetrics increase researchers' visibility and measure attention to their research - Directs to sources for datasets - Provides directions on choosing and using bibliographic management tools - Critically examines the metrics used to evaluate research impact - Aids strategic thinking and informs decision making

Download or read book Bioinformatics written by Zoé Lacroix and published by Academic Press. This book was released on 2003-07-18 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: The heart of the book lies in the collaboration efforts of eight distinct bioinformatics teams that describe their own unique approaches to data integration and interoperability. Each system receives its own chapter where the lead contributors provide precious insight into the specific problems being addressed by the system, why the particular architecture was chosen, and details on the system's strengths and weaknesses. In closing, the editors provide important criteria for evaluating these systems that bioinformatics professionals will find valuable. * Provides a clear overview of the state-of-the-art in data integration and interoperability in genomics, highlighting a variety of systems and giving insight into the strengths and weaknesses of their different approaches.-

Download or read book Data Analysis for the Life Sciences with R written by Rafael A. Irizarry and published by CRC Press. This book was released on 2016-10-04 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers several of the statistical concepts and data analytic skills needed to succeed in data-driven life science research. The authors proceed from relatively basic concepts related to computed p-values to advanced topics related to analyzing highthroughput data. They include the R code that performs this analysis and connect the lines of code to the statistical and mathematical concepts explained.

Download or read book Handbook of Research on Computational Grid Technologies for Life Sciences Biomedicine and Healthcare written by Cannataro, Mario and published by IGI Global. This book was released on 2009-05-31 with total page 960 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book provides methodologies and developments of grid technologies applied in different fields of life sciences"--Provided by publisher.

Download or read book A Biotech Manager s Handbook written by M O'Neill and published by Elsevier. This book was released on 2012-05-02 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: A biotech manager's handbook lays out - in a simple, straightforward manner - for the manager or would-be entrepreneur the basic principles of running a biotech company. Most managers in biotechnology companies are working in their first company or in their first managerial role. Their expertise and experience in the scientific part of the work can be taken as a given but there is a whole range of other skills to be learned and areas of expertise to come to terms with. Small companies do not have big budgets to hire people or time to become an expert in so many areas. The book starts by outlining the state of the biopharmaceutical industry and goes on to explain the importance of planning (no matter what the size of the company). Succeeding chapters deal with the basics of intellectual property, perspectives from a university technology transfer office and how to raise some initial funding from an investor and entrepreneur. - No other 'how to' manual exists for this sector - Written by a range of expert professionals in each area, all in one book - Is the only 'bench to bedside' book covering the whole spectrum of development

Download or read book Flow Cytometry written by Alice Longobardi Givan and published by John Wiley & Sons. This book was released on 2013-04-10 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: Flow cytometry continually amazes scientists with its ever-expanding utility. Advances in flow cytometry have opened new directions in theoretical science, clinical diagnosis, and medical practice. The new edition of Flow Cytometry: First Principles provides a thorough update of this now classic text, reflecting innovations in the field while outlining the fundamental elements of instrumentation, sample preparation, and data analysis. Flow Cytometry: First Principles, Second Edition explains the basic principles of flow cytometry, surveying its primary scientific and clinical applications and highlighting state-of-the-art techniques at the frontiers of research. This edition contains extensive revisions of all chapters, including new discussions on fluorochrome and laser options for multicolor analysis, an additionalsection on apoptosis in the chapter on DNA, and new chapters onintracellular protein staining and cell sorting, including high-speed sorting and alternative sorting methods, as well as traditional technology. This essential resource: Assumes no prior knowledge of flow cytometry Progresses with an informal, engaging lecture style from simpleto more complex concepts Offers a clear introduction to new vocabulary, principles of instrumentation, and strategies for data analysis Emphasizes the theory relevant to all flow cytometry, with examples from a variety of clinical and scientific fields Flow Cytometry: First Principles, Second Edition provides scientists, clinicians, technologists, and students with the knowledge necessary for beginning the practice of flow cytometry and for understanding related literature.

Download or read book Managing Biotechnology written by Francoise Simon and published by John Wiley & Sons. This book was released on 2017-10-16 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive overview of the new business context for biopharma companies, featuring numerous case studies and state-of-the-art marketing models Biotechnology has developed into a key innovation driver especially in the field of human healthcare. But as the biopharma industry continues to grow and expand its reach, development costs are colliding with aging demographics and cost-containment policies of private and public payers. Concurrently, the development and increased affordability of sophisticated digital technologies has fundamentally altered many industries including healthcare. The arrival of new information technology (infotech) companies on the healthcare scene presents both opportunities and challenges for the biopharma business model. To capitalize on new digital technologies from R&D through commercialization requires industry leaders to adopt new business models, develop new digital and data capabilities, and partner with innovators and payers worldwide. Written by two experts, both of whom have had decades of experience in the field, this book provides a comprehensive overview of the new business context and marketing models for biotech companies. Informed by extensive input by senior biotech executives and leading consultancies serving the industry, it analyzes the strategies and key success factors for the financing, development, and commercialization of novel therapeutic products, including strategies for engagement with patients, physicians and healthcare payers. Throughout case studies provide researchers, corporate marketers, senior managers, consultants, financial analysts, and other professionals involved in the biotech sector with insights, ideas, and models. JACQUALYN FOUSE, PhD, RETIRED PRESIDENT AND CHIEF OPERATING OFFICER, CELGENE “Biotech companies have long been innovators, using the latest technologies to enable cutting edge science to help patients with serious diseases. This book is essential to help biotech firms understand how they can–and must–apply the newest technologies including disruptive ones, alongside science, to innovate and bring new value to the healthcare system.” BRUCE DARROW, MD, PhD, CHIEF MEDICAL INFORMATION OFFICER, MOUNT SINAI HEALTH SYSTEM “Simon and Giovannetti have written an essential user’s manual explaining the complicated interplay of the patients who deserve cutting-edge medical care, the biotechnology companies (big and small) creating the breakthroughs, and the healthcare organizations and clinicians who bridge those worlds.” EMMANUEL BLIN, FORMER CHIEF STRATEGY OFFICER AND SENIOR VICE PRESIDENT, BRISTOL-MYERS SQUIBB “If you want to know where biopharma is going, read this book! Our industry is facing unprecedented opportunities driven by major scientific breakthroughs, while transforming itself to address accelerated landscape changes driven by digital revolutions and the emergence of value-based healthcare worldwide. In this ever-changing context, we all need to focus everything we do on the patients. They are why we exist as an industry, and this is ultimately what this insightful essay is really about.” JOHN MARAGANORE, PRESIDENT AND CHIEF EXECUTIVE OFFICER, ALNYLAM PHARMACEUTICALS “Since the mapping of the human genome was completed nearly 15 years ago, the biotechnology industry has led the rapid translation of raw science to today’s innovative medicines. However, the work does not stop in the lab. Delivering these novel medicines to patients is a complex and multifaceted process, which is elegantly described in this new book.”

Download or read book Biotechnology Entrepreneurship written by Craig Shimasaki and published by Academic Press. This book was released on 2014-04-08 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: As an authoritative guide to biotechnology enterprise and entrepreneurship, Biotechnology Entrepreneurship and Management supports the international community in training the biotechnology leaders of tomorrow. Outlining fundamental concepts vital to graduate students and practitioners entering the biotech industry in management or in any entrepreneurial capacity, Biotechnology Entrepreneurship and Management provides tested strategies and hard-won lessons from a leading board of educators and practitioners. It provides a 'how-to' for individuals training at any level for the biotech industry, from macro to micro. Coverage ranges from the initial challenge of translating a technology idea into a working business case, through securing angel investment, and in managing all aspects of the result: business valuation, business development, partnering, biological manufacturing, FDA approvals and regulatory requirements. An engaging and user-friendly style is complemented by diverse diagrams, graphics and business flow charts with decision trees to support effective management and decision making. - Provides tested strategies and lessons in an engaging and user-friendly style supplemented by tailored pedagogy, training tips and overview sidebars - Case studies are interspersed throughout each chapter to support key concepts and best practices. - Enhanced by use of numerous detailed graphics, tables and flow charts

Download or read book The Billion Dollar Molecule written by Barry Werth and published by Simon and Schuster. This book was released on 2013-08-20 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: Join journalist Barry Werth as he pulls back the curtain on Vertex, a start-up pharmaceutical company, and witness firsthand the intense drama being played out in the pioneering and hugely profitable field of drug research. Founded by Joshua Boger, a dynamic Harvard- and Merck-trained scientific whiz kid, Vertex is dedicated to designing—atom by atom—both a new life-saving immunosuppressant drug, and a drug to combat the virus that causes AIDS. You will be hooked from start to finish, as you go from the labs, where obsessive, fiercely competitive scientists struggle for a breakthrough, to Wall Street, where the wheeling and dealing takes on a life of its own, as Boger courts investors and finally decides to take Vertex public. Here is a fascinating no-holds-barred account of the business of science, which includes an updated epilogue about the most recent developments in the quest for a drug to cure AIDS.

Download or read book Cycles of Invention and Discovery written by Venkatesh Narayanamurti and published by Harvard University Press. This book was released on 2016-10-24 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cycles of Invention and Discovery offers an in-depth look at the real-world practice of science and engineering. It shows how the standard categories of “basic” and “applied” have become a hindrance to the organization of the U.S. science and technology enterprise. Tracing the history of these problematic categories, Venkatesh Narayanamurti and Toluwalogo Odumosu document how historical views of policy makers and scientists have led to the construction of science as a pure ideal on the one hand and of engineering as a practical (and inherently less prestigious) activity on the other. Even today, this erroneous but still widespread distinction forces these two endeavors into separate silos, misdirects billions of dollars, and thwarts progress in science and engineering research. The authors contrast this outmoded perspective with the lived experiences of researchers at major research laboratories. Using such Nobel Prize–winning examples as magnetic resonance imaging, the transistor, and the laser, they explore the daily micro-practices of research, showing how distinctions between the search for knowledge and creative problem solving break down when one pays attention to the ways in which pathbreaking research actually happens. By studying key contemporary research institutions, the authors highlight the importance of integrated research practices, contrasting these with models of research in the classic but still-influential report Science the Endless Frontier. Narayanamurti and Odumosu’s new model of the research ecosystem underscores that discovery and invention are often two sides of the same coin that moves innovation forward.

Download or read book Pharmaceutical and Biomedical Project Management in a Changing Global Environment written by Scott D. Babler and published by John Wiley & Sons. This book was released on 2011-01-06 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmaceutical and Biomedical Portfolio Management in a Changing Global Environment explores some of the critical forces at work today in the complex endeavour of pharmaceutical and medical product development. Written by experienced professionals, and including real-world approaches and best practice examples, this new title addresses three key areas – small molecules, large molecules, and medical devices - and provides hard-to-find, consolidated information relevant to and needed by pharmaceutical, biotech, and medical device company managers.

Download or read book Analytics in Healthcare and the Life Sciences written by Thomas H. Davenport and published by Pearson Education. This book was released on 2013-11-04 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: Make healthcare analytics work: leverage its powerful opportunities for improving outcomes, cost, and efficiency.This book gives you thepractical frameworks, strategies, tactics, and case studies you need to go beyond talk to action. The contributing healthcare analytics innovators survey the field’s current state, present start-to-finish guidance for planning and implementation, and help decision-makers prepare for tomorrow’s advances. They present in-depth case studies revealing how leading organizations have organized and executed analytic strategies that work, and fully cover the primary applications of analytics in all three sectors of the healthcare ecosystem: Provider, Payer, and Life Sciences. Co-published with the International Institute for Analytics (IIA), this book features the combined expertise of IIA’s team of leading health analytics practitioners and researchers. Each chapter is written by a member of the IIA faculty, and bridges the latest research findings with proven best practices. This book will be valuable to professionals and decision-makers throughout the healthcare ecosystem, including provider organization clinicians and managers; life sciences researchers and practitioners; and informaticists, actuaries, and managers at payer organizations. It will also be valuable in diverse analytics, operations, and IT courses in business, engineering, and healthcare certificate programs.

Download or read book The SAGE Handbook of Contemporary China written by Weiping Wu and published by SAGE. This book was released on 2018-07-09 with total page 1566 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of contemporary China constitutes a fascinating yet challenging area of scholarly inquiry. Recent decades have brought dramatic changes to China′s economy, society and governance. Analyzing such changes in the context of multiple disciplinary perspectives offers opportunites as well as challenges for scholars in the field known as contemporary China Studies. The SAGE Handbook of Contemporary China is a two-volume exploration of the transformations of contemporary China, firmly grounded in the both disciplinary and China-specific contexts. Drawing on a range of scholarly approaches found in the social sciences and history, an international team of contributors engage with the question of what a rapidly changing China means for the broader field of contemporary China studies, and identify areas of promising future research. Part 1: Context: History, Economy, and the Environment Part 2: Economic Transformations Part 3: Politics and Government Part 4: China on the Global Stage Part 5: China′s Foreign Policy Part 6: National and Nested Identities Part 7: Urbanization and Spatial Development Part 8: Poverty and Inequality Part 9: Social Change Part 10: Future Directions for Contemporary China Studies