Download or read book Managing BRCA Mutation Carriers written by Anees B. Chagpar and published by Springer. This book was released on 2017-07-13 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: As there are a number of nuances in terms of how to manage mutation carriers (both with and without a concomitant diagnosis of breast cancer), this text provides a comprehensive, state-of-the art review of this field. It represents a valuable resource for a myriad of clinicians and healthcare personnel who interface with these patients. The text discusses the latest recommendations for genetic counseling and risk assessment, provides a framework for considering reducing risk in mutation carriers who do not present with a concomitant diagnosis of breast cancer, and finally elucidates the many considerations of managing a breast cancer patient with a BRCA mutation. The text presents a multidisciplinary approach gleaning insights from imaging, breast surgery, gynecology, plastic surgery, medical oncology, radiation oncology and psycho-oncology. Managing BRCA Mutation Carriers will be a useful resource for physicians and healthcare providers from a myriad of disciplines who manage BRCA mutation carriers. All chapters are written by experts in their fields and include the most up to date scientific and clinical information.
Download or read book Ovarian and Fallopian Tube Cancer written by John Kavanagh and published by Wiley-Blackwell. This book was released on 1998-11-25 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book derived from the section of the same name from Cancer in Women, represents a concise overview of the current approaches to the diagnosis and management of ovarian cancer. Therapeutic chapters cover surgery and reconstruction, radiotherpay and adjuvant therapy.
Download or read book Mammography and Beyond written by National Research Council and published by National Academies Press. This book was released on 2001-07-23 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each year more than 180,000 new cases of breast cancer are diagnosed in women in the U.S. If cancer is detected when small and local, treatment options are less dangerous, intrusive, and costly-and more likely to lead to a cure. Yet those simple facts belie the complexity of developing and disseminating acceptable techniques for breast cancer diagnosis. Even the most exciting new technologies remain clouded with uncertainty. Mammography and Beyond provides a comprehensive and up-to-date perspective on the state of breast cancer screening and diagnosis and recommends steps for developing the most reliable breast cancer detection methods possible. This book reviews the dramatic expansion of breast cancer awareness and screening, examining the capabilities and limitations of current and emerging technologies for breast cancer detection and their effectiveness at actually reducing deaths. The committee discusses issues including national policy toward breast cancer detection, roles of public and private agencies, problems in determining the success of a technique, availability of detection methods to specific populations of women, women's experience during the detection process, cost-benefit analyses, and more. Examining current practices and specifying research and other needs, Mammography and Beyond will be an indispensable resource to policy makers, public health officials, medical practitioners, researchers, women's health advocates, and concerned women and their families.
Download or read book Clinical Gynecology written by Eric J. Bieber and published by Cambridge University Press. This book was released on 2015-04-23 with total page 1127 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written with the busy practice in mind, this book delivers clinically focused, evidence-based gynecology guidance in a quick-reference format. It explores etiology, screening, tests, diagnosis, and treatment for a full range of gynecologic health issues. The coverage includes the full range of gynecologic malignancies, reproductive endocrinology and infertility, infectious diseases, urogynecologic problems, gynecologic concerns in children and adolescents, and surgical interventions including minimally invasive surgical procedures. Information is easy to find and absorb owing to the extensive use of full-color diagrams, algorithms, and illustrations. The new edition has been expanded to include aspects of gynecology important in international and resource-poor settings.
Download or read book Genome Stability written by Igor Kovalchuk and published by Academic Press. This book was released on 2021-07-17 with total page 762 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genome Stability: From Virus to Human Application, Second Edition, a volume in the Translational Epigenetics series, explores how various species maintain genome stability and genome diversification in response to environmental factors. Here, across thirty-eight chapters, leading researchers provide a deep analysis of genome stability in DNA/RNA viruses, prokaryotes, single cell eukaryotes, lower multicellular eukaryotes, and mammals, examining how epigenetic factors contribute to genome stability and how these species pass memories of encounters to progeny. Topics also include major DNA repair mechanisms, the role of chromatin in genome stability, human diseases associated with genome instability, and genome stability in response to aging. This second edition has been fully revised to address evolving research trends, including CRISPRs/Cas9 genome editing; conventional versus transgenic genome instability; breeding and genetic diseases associated with abnormal DNA repair; RNA and extrachromosomal DNA; cloning, stem cells, and embryo development; programmed genome instability; and conserved and divergent features of repair. This volume is an essential resource for geneticists, epigeneticists, and molecular biologists who are looking to gain a deeper understanding of this rapidly expanding field, and can also be of great use to advanced students who are looking to gain additional expertise in genome stability. - A deep analysis of genome stability research from various kingdoms, including epigenetics and transgenerational effects - Provides comprehensive coverage of mechanisms utilized by different organisms to maintain genomic stability - Contains applications of genome instability research and outcomes for human disease - Features all-new chapters on evolving areas of genome stability research, including CRISPRs/Cas9 genome editing, RNA and extrachromosomal DNA, programmed genome instability, and conserved and divergent features of repair
Download or read book Probably Someday Cancer written by Kim Horner and published by University of North Texas Press. This book was released on 2019-02-15 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt: After learning that she inherited a BRCA2 genetic mutation that put her at high risk for breast and ovarian cancer, Kim Horner’s doctors urged her to consider having a double mastectomy. But how do you decide whether to have a surgery to remove your breasts to reduce your risk for a disease you don’t have and may never get? Horner shares her struggle to answer that question in Probably Someday Cancer. The mother of a one-year-old boy, she wanted to do whatever would give her the best odds of being around for her son and protect her from breast cancer, which killed her grandmother and great-grandmother in their 40s. Which would give her the best chance at a long healthy life: a double mastectomy or frequent screenings to try to catch any cancer early? The answers weren’t that simple. Based on extensive research, interviews, and personal experience, Horner writes about how and why she ultimately opted for a double mastectomy—the same decision actress Angelina Jolie made for a similar genetic mutation—and the surprising diagnosis that followed. The book explores difficult truths that get overshadowed by upbeat messages about early detection and survivorship—the fact that screenings can miss cancers and that even early-stage breast cancers can spread and become fatal. Probably Someday Cancer is about the author’s efforts to push past her fear and anxiety. This book can help anyone facing hereditary risk of breast and ovarian cancer feel less alone and make informed decisions to protect their health and end the devastation that hereditary cancer has caused for generations in so many families.
Download or read book Resurrection Lily written by Amy Byer Shainman and published by Archway Publishing. This book was released on 2018-12-05 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Resurrection Lily shares a story of inheritance and intuition, of what can surface in the body and the spirit when linked by DNA. As Amy Byer Shainman discovers she has inherited a BRCA gene mutation that puts her at high risk of developing certain cancers, she struggles to come to terms with preventively removing her breasts when she does not have a breast cancer diagnosis. Through her experience making decisions about her health, Amy becomes invigorated with purpose and establishes herself as a leading advocate for those with BRCA and other hereditary cancer syndromes, tirelessly working to educate others facing the same daunting reality. Painting a timely and moving portrait of what it feels like to carry a BRCA gene mutation, Resurrection Lily provides firsthand insight into the patient experience. Weaved throughout Amy’s open and vulnerable story is the expertise of her doctors, education from top medical experts in cancer genetics, and whispered lifesaving guidance from her grandmother Lillian.
Download or read book Understanding BRCA written by Clarissa Foster and published by . This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Do you have a close relative who has died from, or is experiencing, aggressive breast, ovarian or prostate cancer? Have they been tested for the BRCA gene mutation? Have you? At the age of 35 and following the death of her mother from ovarian cancer, Clarissa Foster was found to carry a harmful mutation in the BRCA2 gene which drastically increased her risk of developing breast and ovarian cancer. She searched for a book that would help her to understand the full extent of what it meant to carry a harmful mutation, the options available to her to lower her risk and, most importantly, how it would feel to undergo risk-reducing surgery. Finding nothing that answered her needs, she set about reading all the available medical literature and liaising with relevant medical professionals to answer her questions. This book is the result of that research and of the decision she took based on it – to have a bilateral mastectomy and salpingo-oophorectomy. Within the context of her own painful experience of family cancer and of elective surgery, Clarissa explains what the BRCA mutation is, what it signifies, what the individual’s choices are and what the fall out can be in terms of a woman’s body image, identity and sexual functioning."--Publisher's description.
Download or read book Positive Results written by Joi L. Morris and published by Prometheus Books. This book was released on 2010-06-03 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique and important guidebook is a single, comprehensive source of information and advice to help women (and some men) at high risk for breast and for ovarian cancer because of family history and genetic profile. One part memoir, three parts "how to" manual, Positive Results explains in a clear and steady manner the myths and realities of "the breast cancer genes." It lays out all the options in easy-to-follow, compassionate language. It will help women and men decide if they want to pursue genetic testing, guide them in interpreting their test results, and give them a sound basis for making the life-saving decisions required to manage their risks. Authors Joi Morris and Dr. Ora Karp Gordon cover all of the latest medical options, including genetic testing for breast cancer risk, breast cancer surveillance, assessing risk, mastectomy and breast reconstruction techniques, ovarian cancer surveillance, surgery, managing menopause, and cancer risks in men who carry mutations on BRCA genes. Along the way, Joi tells her personal story and that of other women and men who have made the gut-wrenching decisions required to survive in this world of astronomical risk. At the age of forty-two, Joi learned that she has a genetic mutation on a gene known as BRCA2. The test results meant that her risk of getting breast cancer could be as high as 84 percent by age seventy, and that her risk for ovarian cancer was also high. Compounding her risk was the fact that her mother had developed breast cancer in her forties. After much research and consultation, the result of which is this book, Joi made the difficult decision of undergoing prophylactic mastectomies. This straightforward and practical approach combined with the poignant personal experience of a woman at risk facing these challenging decisions will provide readers with the feeling that they have had the benefit of a long conversation with both a trusted physician and a friend who has just gone through the same uncertainties they are facing.
Download or read book Confronting Hereditary Breast and Ovarian Cancer written by Sue Friedman and published by JHU Press. This book was released on 2012-03-01 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Be informed. Be empowered. Be well." If you are concerned that the cancer in your family is hereditary, you face difficult choices. Should you have a blood test that may reveal whether you have a high likelihood of disease? Do you preemptively treat a disease that may never develop? How do you make decisions now that will affect the rest of your life? This helpful, informative guide answers your questions as you confront hereditary breast and ovarian cancer. Developed by Facing Our Risk of Cancer Empowered (FORCE), the nation’s only nonprofit organization dedicated to supporting families affected by hereditary breast and ovarian cancer, this book stands alone among breast and ovarian cancer resources. Equal parts health guide and memoir, it defines complex issues facing previvors and survivors and provides solutions with a fresh, authoritative voice. Written by three passionate advocates for the hereditary cancer community who are themselves breast cancer survivors, Confronting Hereditary Breast and Ovarian Cancer dispels myths and misinformation and presents practical risk-reducing alternatives and decision-making tools. Including information about genetic counseling and testing, preventive surgery, and fertility and family planning, as well as explanations of health insurance coverage and laws protecting genetic privacy, this resource tackles head-on the challenges of living in a high-risk body. Confronting hereditary cancer is a complex, confusing, and highly individual journey. With its unique combination of the latest research, expert advice, and compelling personal stories, this book gives previvors, survivors, and their family members the guidance they need to face the unique challenges of hereditary cancer.
Download or read book Changing Paradigms in the Management of Breast Cancer written by Marissa Howard-McNatt and published by Springer. This book was released on 2017-09-12 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text is designed to present a comprehensive and state-of the-art approach to the management of breast cancer within the fields of surgery, medical oncology, and radiation oncology. Sections address changes in these fields. These areas include breast imaging, management of the axilla, atypical breast lesions, surgical margins, new techniques in breast reconstruction, and nipple sparing and contralateral mastectomies. Subsequent chapters focus on issues in medical oncology including, triple negative breast cancer and metastatic breast disease. New paradigms in radiation oncology are examined. Breast cancer treatment in the elderly and in young women, and genetic risk in breast cancer management is also be discussed. Written by experts in their field, each of these sections addresses advances and changes in the field. A brief review of the existing literature addressing the particular topic follows in each section. The text concludes with chapters on pathological issues and advances in radiation oncology. As access to a comprehensive multidisciplinary resource such as this is currently limited in the literature, Changing Paradigms in the Management of Breast Cancer represents the first single source to provide information on advances and outcomes for the physician caring for breast cancer patients in a multidisciplinary setting.
Download or read book Management of the Patient at High Risk for Breast Cancer written by Nora M. Hansen and published by Springer Science & Business Media. This book was released on 2013-01-08 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: Management of the Patient at High Risk for Breast Cancer provides a state-of-the art review of patients who are at high risk for breast cancer, how to identify them, the tools available for risk assessment and quantification and indications for genetic counseling and testing. The book summarizes the high risk breast imaging options, including newest techniques and schedules. Pathologic evaluation of high risk lesions are featured as well as the management issues surrounding these lesions. The volume also covers the management of concomitant cancer risk and screening strategies. A concise, yet comprehensive overview of the current status of the topic, Management of the Patient at High Risk for Breast Cancer serves as a useful resource for physicians and researchers dealing with and interested in patients at high risk for breast cancer.
Download or read book Management of Breast Diseases written by Ismail Jatoi and published by Springer. This book was released on 2016-11-16 with total page 656 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text is intended as a practical guide for physicians and surgeons who treat diseases of the breast, both benign and malignant. Thus, general surgeons, internists, family practitioners, gynecologists, surgical oncologists, radiation oncologists, and medical oncologists will find this book useful. The management of breast diseases requires a multidisciplinary approach, and this textbook therefore includes the views of a wide range of specialists from throughout the world. Today the treatment of breast diseases is largely predicated on the results of randomized prospective trials. The results of many clinical trials are discussed in detail, and readers will find this book to be a useful guide to the evidence-based treatment of breast diseases. The revised edition provides a comprehensive update of the previous version of the book. Specifically, it contains 2 new chapters: “Molecular Classification of Breast Cancer” and “Breast Cancer Molecular Testing for Prognosis and Prediction”. In addition, since publication of the previous edition, the results of numerous adjuvant systemic therapy and neo-adjuvant systemic therapy trials have been published, and this edition provides a comprehensive overview of these trials and discusses how they have changed the management of breast cancer. Similarly, there have been, in the last few years, important new developments in the local therapy of breast cancer. This edition discusses these new developments and particularly recent developments and controversies concerning the management of the axilla in patients with primary breast cancer. New guidelines with respect to radiotherapy are also reviewed and discussed. Finally, all chapters in the book are thoroughly revised and updated to provide readers with current understanding of the biology and treatment of breast cancer.
Download or read book Surgeon s Role in Multidisciplinary Breast Management An Issue of Surgical Clinics written by George M. Fuhrman and published by Elsevier Health Sciences. This book was released on 2013-04-28 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive and important issue devoted to multidisciplinary breast management! Topics will include neoadjuvant chemotherapy, pathology of invasive breast disease, management of high risk lesions, genetic predisposition syndromes, radiation therapy, surgical management of the breast–mastectomy and breast conservation, management of the axilla, management of ductal carcinoma in situ, breast reconstruction, adjuvant therapy, screening, imaging, and image guided biopsy techniques for breast cancer, benign breast disease, and much more!
Download or read book Advances in Breast Cancer Management written by William J. Gradishar and published by Springer Science & Business Media. This book was released on 2007-11-29 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume highlights many of the important advances that have improved our understanding of the biology and therapeutics of breast cancer. The initial discussion focuses on the evolving understanding of the genetics of breast cancer. In addition to the well known genetic mutations BRCA1 and BRCA2, other mutations that have recently been identified are discussed.
Download or read book Cancer Susceptibility written by Michelle Webb and published by Humana Press. This book was released on 2010-09-02 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past two decades, spectacular advances have been made in our understanding of the molecular genetics of cancer, leading to the pursuit of identifying genes that, when mutated, result in an increased susceptibility to the disease. In Cancer Susceptibility: Methods and Protocols, experts in the field bring together the most recent technological developments for identifying and screening cancer susceptibility genes. Divided into two clear sections, the book begins with gene identification, which updates and informs scientists working at identifying novel cancer susceptibility genes, while the second part deals with mutation screening technologies that aid scientists and clinicians working to translate this knowledge into the clinic. Written in the highly successful Methods in Molecular BiologyTM series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Cancer Susceptibility: Methods and Protocols is a timely collection that seeks to provide researchers with the tools to predict and combat this terrible disease.
Download or read book Management of Benign and Malignant Breast Disease An Issue of Obstetrics and Gynecology Clinics E Book written by Patrice M Weiss and published by Elsevier Health Sciences. This book was released on 2022-02-24 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue of Obstetrics and Gynecology Clinics, guest editors Patrice Weiss and Jessica F. Partin bring their considerable expertise to the topic of Management of Benign and Malignant Breast Disease. - Provides in-depth reviews on the latest in Management of Benign and Malignant Breast Disease. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.
