Download or read book Management of Dysregulated Immune Response in the Critically Ill written by Zsolt Molnar and published by Springer Nature. This book was released on 2023-03-11 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, part of the European Society of Intensive Care Medicine (ESICM) textbook series, deals with dysregulated host response a relatively new term introduced by the Sepsis-3 definitions in 2016. In contrast to systemic inflammatory response syndrome (SIRS) that has been used for nearly 30 years, this is a fundamentally new concept, which requires some sort of a paradigm shift in the way of thinking of critical care physicians. This change obviously requires time and after 5 years, time is ripe to summarize the knowledge in the form of a comprehensive book. The book is split in 4 sections. In the first one, the host immune response is explained in 11 chapters, followed by the next part, summarizing the possible tools for assessment at the bedside. The third and the fourth parts focus on the effects of dysregulated immune response on vital organ function and on the possible ways of immunomodulation. Written by internationally acclaimed experts of the field, the book is of value for all those intensivists and allied professionals working in ICUs.
Download or read book Immune Response in the Critically Ill written by John C. Marshall and published by Springer Science & Business Media. This book was released on 2002-01-21 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings together basic scientists or clinicians from a variety of different backgrounds - immunology, infectious diseases or critical care - who share a common interest in understanding the changes that occur in immune responses in sepsis. It provides an up-to-date and unrivalled synthesis of current research in this rapidly developing field.
Download or read book Stress Challenges and Immunity in Space written by Alexander Choukèr and published by Springer. This book was released on 2020-12-03 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explains how stress – either psychological or physical – can activate and/or paralyse human innate or adaptive immunity. Adequate immunity is crucial for maintaining health, both on Earth and in space. During space flight, human physiology is specifically challenged by complex environmental stressors, which are most pronounced during lunar or interplanetary missions. Adopting an interdisciplinary approach, the book identifies the impact of these stressors – the space exposome – on immunity as a result of (dys-)functions of specific cells, organs and organ networks. These conditions (e.g. gravitation changes, radiation, isolation/confinement) affect immunity, but at the same time provide insights that may help to prevent, diagnose and address immune-related health alterations. Written by experts from academia, space agencies and industry, the book is a valuable resource for professionals, researchers and students in the field of medicine, biology and technology. The chapters “The Impact of Everyday Stressors on the Immune System and Health”, “Stress and Radiation Responsiveness” and “Assessment of Radiosensitivity and Biomonitoring of Exposure to Space adiation” are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Download or read book Post Intensive Care Syndrome written by Jean-Charles Preiser and published by Springer Nature. This book was released on 2019-08-31 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, part of the European Society of Intensive Care Medicine textbook series, provides detailed up-to-date information on the physical, cognitive, and psychological impairments that are frequently present following a stay in an intensive care unit and examines in depth the available preventive and therapeutic strategies, including adapted rehabilitation programs. Beyond acquainting readers with the multiple facets of post-intensive care syndrome (PICS), the book aims to promote the effective follow-up of patients, thereby enhancing their ability to work and their functional autonomy, and to identify risk factors for the development of PICS as a stimulus to beneficial organizational changes in intensive care departments. The background to the book is the realization by healthcare providers that the quality of life of patients who have required a stay in an intensive care unit can be severely impaired or even become unacceptable. All too often, the diverse sequelae are overlooked by specialists of other disciplines. Moreover, families and caregivers are also at high risk of post-traumatic stress disorder and depression. The European Society of Intensive Care Medicine has developed the Lessons from the ICU series with the vision of providing focused and state-of-the-art overviews of central topics in Intensive Care and optimal resources for clinicians working in Intensive Care. This book, written by renowned experts in the field, will facilitate the transmission of key knowledge with significant clinical and financial benefits.
Download or read book Sepsis Management in Resource limited Settings written by Arjen M. Dondorp and published by Springer. This book was released on 2019-02-08 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is open access under a CC BY 4.0 license. It constitutes a unique source of knowledge and guidance for all healthcare workers who care for patients with sepsis and septic shock in resource-limited settings. More than eighty percent of the worldwide deaths related to sepsis occur in resource-limited settings in low and middle-income countries. Current international sepsis guidelines cannot be implemented without adaptations towards these settings, mainly because of the difference in local resources and a different spectrum of infectious diseases causing sepsis. This prompted members of the Global Intensive Care working group of the European Society of Intensive Care Medicine (ESICM) and the Mahidol-Oxford Tropical Medicine Research Unit (MORU, Bangkok, Thailand) - among which the Editors – to develop with an international group of experts a comprehensive set of recommendations for the management of sepsis in resource-limited settings. Recommendations are based on both current scientific evidence and clinical experience of clinicians working in resource-limited settings. The book includes an overview chapter outlining the current challenges and future directions of sepsis management as well as general recommendations on the structure and organization of intensive care services in resource-limited settings. Specific recommendations on the recognition and management of patients with sepsis and septic shock in these settings are grouped into seven chapters. The book provides evidence-based practical guidance for doctors in low and middle income countries treating patients with sepsis, and highlights areas for further research and discussion.
Download or read book Medical Immunology written by Gabriel Virella and published by CRC Press. This book was released on 2007-03-28 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: With an abundance of illustrations, diagrams, and algorithms, this sixth edition of Medical Immunology provides a reader-friendly review of critical material on the current diagnostic and clinical applications of immunology. Organized into four sections that describe clinical applications, methodological advances, immunological diseases, and innova
Download or read book Covid 19 Airway Management and Ventilation Strategy for Critically Ill Older Patients written by Nicola Vargas and published by Springer Nature. This book was released on 2020-08-25 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the issues and challenges that clinicians encountered in the management of older critically ill patients during the Covid-19 pandemic, and offers practical information on how to manage them. Older adults are more susceptible to complications such as acute respiratory distress syndrome (ARDS) as a result of viral pneumonia. In addition, they often have multiple comorbidities and are commonly frail, which means their various organs and systems, such as the respiratory system, have reduced functional reserves. As such, older adults are less able to react to acute stressors. During the current Covid-19 pandemic, older adult patients' mortality is increased. Further, the infection and death rates of elderly people in nursing homes and health care institutions are high. Management of older adults with Covid is complicated. The reduced availability of beds may limit their access to ICU. Moreover, the prognosis may be poor, and airway management and ventilation strategies have to take into account various clinical and physiological characteristics specific to older patients. This book is addressed to all allied professionals involved in the management of older critically ill patients and presents information collected and practical lessons learned from the clinical daily management of this population during the pandemic.
Download or read book The Washington Manual of Critical Care written by Marin Kollef and published by Lippincott Williams & Wilkins. This book was released on 2024-06-30 with total page 989 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part of the popular Washington Manual® handbook series, The Washington Manual® of Critical Care provides concise, high-yield content that reflects today’s fast-changing advances in the field. Edited by Drs. Marin H. Kollef, Vladimir N. Despotovic, Bryan D. Kraft, Rachel K. McDonald, and Nguyet Nguyen, and written by teams of Washington University residents and faculty, the fourth edition focuses on the essential information you need to know, using a brief, bulleted format, along with numerous figures, tables, algorithms, and images throughout. In one convenient, portable resource, you’ll find complete coverage of bedside diagnosis and management of the most frequently encountered illnesses and problems seen in the ICU—all at your fingertips for quick review and reference.
Download or read book New Strategies for Treatment of Sepsis written by Antonio Mirijello and published by Mdpi AG. This book was released on 2021-12-27 with total page 146 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book represents a collection of paper from different specialists involved in the management of septic patients, aimed to disseminate the knowledge in the field of sepsis, particularly to non-intensivists physicians.
Download or read book Mechanisms of Vascular Disease written by Robert Fitridge and published by University of Adelaide Press. This book was released on 2011 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.
Download or read book Continuous Renal Replacement Therapy written by John A. Kellum and published by Oxford University Press. This book was released on 2016 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: Continuous Renal Replacement Therapy provides concise, evidence-based, bedside guidance for the management of critically ill patients with acute renal failure, offering quick reference answers to clinicians' questions about treatments and situations encountered in daily practice.
Download or read book Annual Update in Intensive Care and Emergency Medicine 2021 written by Jean-Louis Vincent and published by Springer Nature. This book was released on 2021-09-03 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Annual Update compiles reviews of the most recent developments in experimental and clinical intensive care and emergency medicine research and practice in one comprehensive book. The chapters are written by well recognized experts in these fields. The book is addressed to everyone involved in internal medicine, anesthesia, surgery, pediatrics, intensive care and emergency medicine.
Download or read book Handbook of Sepsis written by W. Joost Wiersinga and published by Springer. This book was released on 2018-04-13 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practically oriented book provides an up-to-date overview of all significant aspects of the pathogenesis of sepsis and its management, including within the intensive care unit. Readers will find information on the involvement of the coagulation and endocrine systems during sepsis and on the use of biomarkers to diagnose sepsis and allow early intervention. International clinical practice guidelines for the management of sepsis are presented, and individual chapters focus on aspects such as fluid resuscitation, vasopressor therapy, response to multiorgan failure, antimicrobial therapy, and adjunctive immunotherapy. The closing section looks forward to the coming decade, discussing novel trial designs, sepsis in low- and middle-income countries, and emerging management approaches. The book is internatio nal in scope, with contributions from leading experts worldwide. It will be of value to residents and professionals/practitioners in the fields of infectious diseases and internal medicine, as well as to GPs and medical students.
Download or read book Coronavirus Disease COVID 19 Pathophysiology Epidemiology Clinical Management and Public Health Response volume I C written by Zisis Kozlakidis and published by Frontiers Media SA. This book was released on 2023-04-25 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume I.C An outbreak of a respiratory disease first reported in Wuhan, China in December 2019 and the causative agent was discovered in January 2020 to be a novel betacoronovirus of the same subgenus as SARS-CoV and named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Coronavirus disease 2019 (COVID-19) has rapidly disseminated worldwide, with clinical manifestations ranging from mild respiratory symptoms to severe pneumonia and a fatality rate estimated around 2%. Person to person transmission is occurring both in the community and healthcare settings. The World Health Organization (WHO) has recently declared the COVID-19 epidemic a public health emergency of international concern. The ongoing outbreak presents many clinical and public health management challenges due to limited understanding of viral pathogenesis, risk factors for infection, natural history of disease including clinical presentation and outcomes, prognostic factors for severe illness, period of infectivity, modes and extent of virus inter-human transmission, as well as effective preventive measures and public health response and containment interventions. There are no antiviral treatment nor vaccine available but fast track research and development efforts including clinical therapeutic trials are ongoing across the world. Managing this serious epidemic requires the appropriate deployment of limited human resources across all cadres of health care and public health staff, including clinical, laboratory, managerial and epidemiological data analysis and risk assessment experts. It presents challenges around public communication and messaging around risk, with the potential for misinformation and disinformation. Therefore, integrated operational research and intervention, learning from experiences across different fields and settings should contribute towards better understanding and managing COVID-19. This Research Topic aims to highlight interdisciplinary research approaches deployed during the COVID-19 epidemic, addressing knowledge gaps and generating evidence for its improved management and control. It will incorporate critical, theoretically informed and empirically grounded original research contributions using diverse approaches, experimental, observational and intervention studies, conceptual framing, expert opinions and reviews from across the world. The Research Topic proposes a multi-dimensional approach to improving the management of COVID-19 with scientific contributions from all areas of virology, immunology, clinical microbiology, epidemiology, therapeutics, communications as well as infection prevention and public health risk assessment and management studies.
Download or read book SARS MERS and other Viral Lung Infections written by David S. Hui and published by European Respiratory Society. This book was released on 2016-06-01 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: Viral respiratory tract infections are important and common causes of morbidity and mortality worldwide. In the past two decades, several novel viral respiratory infections have emerged with epidemic potential that threaten global health security. This Monograph aims to provide an up-to-date and comprehensive overview of severe acute respiratory syndrome, Middle East respiratory syndrome and other viral respiratory infections, including seasonal influenza, avian influenza, respiratory syncytial virus and human rhinovirus, through six chapters written by authoritative experts from around the globe.
Download or read book Textbook of Polytrauma Management written by Hans-Christoph Pape and published by Springer Nature. This book was released on 2022-05-31 with total page 661 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook is a fully updated and revised third edition of a highly successful practical guide to the care of the polytrauma patient. Broadening its readership to students, this new edition comprehensively describes the clinical course of multiple and severe injuries, from the accident scene to rehabilitation. It provides essential practical information on the care of patients both with blunt and penetrating trauma to multiple body regions, and discusses the management of truncal injuries (head, chest, abdomen) as well as fractures of the extremities, pelvis and spine. Further, the book highlights associated injuries that may alter decisions concerning patients with polytrauma. This new, revised edition takes full account of recent developments, including the increasing economic pressure on health care systems, prehospital treatment, changes in trauma systems and related education, and the improved survival of polytrauma patients. Also covering improved monitoring options along with issues in late patient outcomes and rehabilitation this work will greatly assist students, emergency personnel, trauma surgeons, orthopaedic traumatologists, and anesthesiologists.
Download or read book ISCCM Manual of RRT and ECMO in ICU written by Rajesh Chandra Mishra and published by Jaypee Brothers Medical Publishers. This book was released on 2020-02-29 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt:
