Download or read book Magnetic Resonance Imaging in Movement Disorders written by Paul Tuite and published by Cambridge University Press. This book was released on 2013-10-10 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetic Resonance Imaging in Movement Disorders is the first book to focus in detail on MRI in a range of movement disorders. Since MRI was first employed in imaging Parkinson's disease, the number of imaging techniques and their application in diagnosis and management has extended widely. The book shows various imaging strategies ranging from functional, structural and chemical methods as they relate to both motor and non-motor aspects of Parkinson's disease and other conditions such as Huntington's disease and dystonia. Chapters on MRI in surgery and using MRI as a potential outcome measure in clinical trials show the clinical relevance of methods. Novel methods including DTI, tractography and resting case studies are described in detail. The book also summarises the relevance of fMRI to various aspects of movement disorders. Magnetic Resonance Imaging in Movement Disorders is essential reading for neurologists, radiologists and movement disorder specialists.
Download or read book Imaging in Movement Disorders Imaging Applications in Non Parkinsonian and Other Movement Disorders written by Marios Politis and published by Academic Press. This book was released on 2018-11-21 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: Imaging in Movement Disorders: Imaging in Other Movement Disorders and Dementia, Volume 143 provides an up-to-date textbook on the use of imaging modalities across the spectrum of movement disorders and dementias. The book brings together lessons learned from neuroimaging tools in the content of movement disorders, including idiopathic and sporadic forms of Parkinson’s disease, Huntington’s disease, Atypical Parkinsonism, Dystonia, Essential Tremor, and more. Specific chapters cover Neuroimaging Applications in Dystonia, Neuroimaging Applications in Essential Tremor, Neuroimaging applications in Restless Leg Syndrome, Neuroimaging Application in Tourette's Syndrome and TIC Disorders, Neuroimaging Applications in Functional Movement Disorders, and Neuroimaging Applications in Cerebellar Disorders. Addition sections cover Molecular Imaging of Parkinson's Disease Cognitive Impairment, Structural MRI in Parkinson's Disease Cognitive Impairment, Functional MRI in Parkinson's Disease Cognitive Impairment, Molecular Imaging of Dementia with Lewy Bodies, Structural and Functional MRI of Dementia with Lewy Bodies, Transcranial Sonography in Movement Disorders, Imaging transplantation in Movement Disorders, Hybrid PET-MRI Applications in Movement Disorders, amongst other topics. Offers a complete review of the application of neuroimaging tools in Dystonia, Essential Tremor, Restless Leg Syndrome, Tourette’s syndrome, and Tic and Movement Disorders Covers the role of neuroimaging research in movement disorder dementias Presents the importance of imaging techniques as biomarkers of disease progression and treatment response in therapeutic trials
Download or read book Magnetic Resonance Imaging in Deep Brain Stimulation written by Alexandre Boutet and published by Springer Nature. This book was released on 2022-11-28 with total page 127 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the roles magnetic resonance imaging (MRI) can play in deep brain stimulation (DBS). DBS therapeutically modulates aberrant neural circuits implicated in a broad range of neurological disorders. Following surgical insertion, an electrode placed into the desired brain target generates constant electricity, analogous to a cardiac pacemaker. Most commonly employed in movement disorders such as Parkinson’s disease, dystonia, and tremor, DBS is also being investigated for use in psychiatric and cognitive disorders, including depression and Alzheimer’s disease. It is estimated that more than 230,000 patients have undergone DBS surgery worldwide. Imaging techniques, specifically MRI, have played key roles in the preoperative and postoperative aspects of DBS. This book focuses on the established as well as the innovative roles of MRI in DBS. MRI and DBS are first introduced from an historical perspective and a review of the clinical aspects of DBS is performed. Then, the preoperative and postoperative applications of MRI in DBS are covered. The crucial aspect of MRI safety in these patients is also discussed. Finally, possible upcoming MRI applications for patients with DBS are discussed in a future directions chapter. Chapters are written by experts from the University of Toronto, a world leader in the field of DBS, alongside international co-authors to ensure a thorough review of the topics. This is an ideal guide for both clinicians (neurosurgeons, neurologists, psychiatrists, and neuroradiologists) and researchers as well as trainees interested in neuroimaging for DBS.
Download or read book Imaging in Movement Disorders Imaging in Atypical Parkinsonism and Familial Movement Disorders written by and published by Academic Press. This book was released on 2018-11-05 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: Imaging in Movement Disorders: Imaging in Atypical Parkinsonism and Familial Movement Disorders, Volume 142, addresses the use of imaging modalities across the spectrum of movement disorders and dementias. Over the last decades, advances in neuroimaging tools have played a pivotal role in expanding our understanding of disease aetiology and pathophysiology, identifying biomarkers to monitor disease progression, aiding differential diagnosis and in the identification of novel targets for therapeutic intervention. This updated volume covers PET Molecular Imaging in Atypical Parkinsonism, SPECT Molecular Imaging in Atypical Parkinsonism, Structural MRI in Atypical Parkinsonism, Functional MRI in Atypical Parkinsonism, and more. Offers a complete review of the applications of neuroimaging tools in Atypical Parkinsonism, familial Parkinson’s disease and Huntington’s disease Discusses the role of neuroimaging modalities, including SPECT, PET, and structural and functional MRI Includes sections on potential clinical applications and future directions
Download or read book Imaging in Movement Disorders written by and published by Academic Press. This book was released on 2018-10-09 with total page 485 pages. Available in PDF, EPUB and Kindle. Book excerpt: Imaging Methodology and Applications in Parkinson's Disease, Volume 141, provides an up-to-date and comprehensive textbook on the use of imaging modalities across the spectrum of movement disorders and dementias. Over the last decades, advances in neuroimaging tools has played a pivotal role in expanding our understanding of disease etiology and pathophysiology, identifying biomarkers to monitor disease progression, aiding differential diagnosis, and in the identification of novel targets for therapeutic intervention. This book brings together lessons learned from neuroimaging tools in movement disorders, including chapters on Advances in PET Methodology, Advances in MRI Methodology, Advances in SPECT Methodology, Hybrid PET/MRI Methodology, and more. Provides an up-to-date and comprehensive textbook addressing all aspects of neuroimaging in movement disorders Offers a complete review of advances in core imaging methodology and the application of neuroimaging tools Represents an indispensable educational and research reference of value to all movement disorder specialists, physicians, researchers and students
Download or read book Neuroimaging of Movement Disorders written by Fatta B. Nahab and published by Springer Science & Business Media. This book was released on 2013-06-03 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the diagnosis and treatment of movement disorders, the use of neuroimaging has expanded widely and has been an exciting, important modality for unlocking the causes of abnormal motor control. With ever improving machinery, data collection techniques and analysis methods, researchers are now being presented with an exponentially increasing amount of data that they must wade through and interpret in the context of existing knowledge about movement disorders. In Neuroimaging in Movement Disorders, the editors have produced a gold-standard resource that brings together an impressive international group of authorities in their respective fields to outline the current state of knowledge. Controversies, such as conflicting findings and methodological limitations, are covered and provide the reader with a comprehensive yet pragmatic understanding of the state of science. The chapters offer both comprehensive reviews of various neuroimaging methods and also more in-depth summaries of the contributions made by neuroimaging in individual movement disorders. Although many of the neuroimaging methods that are discussed have not been routinely used in clinical practice, the authors skillfully provide the reader with adequate detail to understand the requirements for using these methods and in some cases even the starting knowledge to begin local implementation. Neuroimaging in Movement Disorders is an indispensable reference that will be of value to all physicians and researchers involved in the care of patients with movement disorders.
Download or read book Imaging in Movement Disorders Imaging in Movement Disorder Dementias and Rapid Eye Movement Sleep Behavior Disorder written by and published by Academic Press. This book was released on 2019-01-23 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: Imaging in Movement Disorders: Imaging in Movement Disorder Dementias and Rapid Eye Movement Sleep Behavior Disorder, Volume 144 provides an up-to-date textbook on the use of imaging modalities across the spectrum of movement disorders and dementias. The book brings together lessons learned from neuroimaging tools in the content of movement disorders, including chapters on Molecular Imaging of Dementia with Lewy Bodies, Structural and Functional Magnetic Resonance Imaging of Dementia with Lewy Bodies, Network Imaging in Parkinsonian and Other Movement Disorders: Network Dysfunction and Clinical Correlates, Neuroimaging of Rapid Eye Movement Sleep Behavior Disorder, Hybrid PET-MRI Applications in Movement Disorders, and more. Covers the role of neuroimaging research in movement disorder dementias Presents the importance of imaging techniques as biomarkers of disease progression and treatment response in therapeutic trials
Download or read book Imaging in Movement Disorders Imaging in Movement Disorder Dementias and Rapid Eye Movement Sleep Behavior Disorder written by and published by Academic Press. This book was released on 2019-01-16 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Imaging in Movement Disorders: Imaging in Movement Disorder Dementias and Rapid Eye Movement Sleep Behavior Disorder, Volume 144 provides an up-to-date textbook on the use of imaging modalities across the spectrum of movement disorders and dementias. The book brings together lessons learned from neuroimaging tools in the content of movement disorders, including chapters on Molecular Imaging of Dementia with Lewy Bodies, Structural and Functional Magnetic Resonance Imaging of Dementia with Lewy Bodies, Network Imaging in Parkinsonian and Other Movement Disorders: Network Dysfunction and Clinical Correlates, Neuroimaging of Rapid Eye Movement Sleep Behavior Disorder, Hybrid PET-MRI Applications in Movement Disorders, and more.
Download or read book Pathologic Substrates of Quantitative Magnetic Resonance Imaging in Parkinsonisms written by Ernest Weider Wang and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Parkinsonisms -- a set of diseases characterized by motor presentations reminiscent of Parkinson's disease (PD) -- are progressive and debilitating neurodegenerative disorders. Motor signs and symptoms advance from tremors, weakness, and loss of balance, to significant challenges in eating, grooming, and other activities of daily living. Concurrent non-motor symptoms include mood disturbances, hallucinations, and cognitive decline. Presently, pharmaceutic and interventional therapies are available for symptomatic relief, but there are no curative measures. Within the wider class of movement disorders, parkinsonisms -- which include progressive supranuclear palsy, multiple system atrophy, and corticobasal degeneration -- are distinguished by the loss of dopaminergic neurons in the substantia nigra pars compacta (SNc), a midbrain structure that provides dopaminergic input to the striatum to regulate the motor pathways of the basal ganglia. Currently, it is unclear as to why these nigrostriatal neurons are particularly vulnerable. Outside of rare hereditary mutations predisposing individuals to PD, the majority of parkinsonism cases have no definitive etiology. Our best estimation is that they occur as a result of complex interactions between genetic and environmental risk factors. In the past few decades, there has been tremendous effort to develop magnetic resonance imaging (MRI) biomarkers that are sensitive to parkinsonism neuropathologic changes, both for the differential diagnosis of parkinsonisms and for the monitoring of their progression. MRI has the advantage of being a safe and high-resolution medical imaging capability. It currently is used only in ancillary studies investigating parkinsonisms. But researchers have continued to experiment with scanners, sequences, and advanced data processing techniques in the search of novel and robust quantitative MRI metrics. Presently, there are several MRI modalities being studied, but two frequent approaches are susceptibility MRI (sMRI) and diffusion tensor imaging (DTI), which respectively reflect iron-related changes and general alterations in tissue microstructural integrity. Both techniques have detected parkinsonism-related changes in cross-sectional and longitudinal studies of the SNc. But despite these promising findings, there is little known about the exact pathologies they represent. In this work, I discuss in greater depth the issues outlined above and present original research that advances our understanding of the pathologic substrates underling MRI in parkinsonisms. In first chapter, I begin by discussing parkinsonisms as a set of similarly presenting clinical syndromes with unique yet overlapping neuropathologies. In the second chapter, I provide an overview of sMRI and DTI as quantitative MRI biomarkers. I follow this in the third chapter with a demonstration of their ability to capture clinically relevant changes within limbic structures among parkinsonisms. In the fourth chapter I address the issue at hand and examine the pathologic substrates underlying sMRI and DTI signals in the parkinsonism SNc. Then in the fourth and fifth chapters, I respectively study a potential gene-environment interaction using sMRI and DTI of the SNc, and integrate the preceding findings to point to future directions. As a whole, this dissertation is by no means an exhaustive review or study of MRI in parkinsonisms. It addresses, however, key gaps in our current understanding and lays important groundwork for future investigations.
Download or read book Functional Imaging in Movement Disorders written by W. R. Wayne Martin and published by CRC Press. This book was released on 2019-08-15 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1990, this indispensable volume brings together authoritative, up-to-date, critical accounts of the present status of positron emission tomography (PET) in the study of movement disorders both in terms of the basic science relevant to PET and the clinical science related to the study of specific disease processes. For better understanding, it includes a review of the basic principles of PET and tracer kinetics. It also reviews clinical studies concerning Parkinson's and Huntington's disease, as well as some of the less common movement disorders such as progressive supranuclear palsy, olivopontocerebellar atrophy, and dystonia. Throughout the text, it emphasizes PET as a tool for the quantitative measurement of meaningful biochemical and physiological processes. This state-of-the-art work provides a perspective concerning the degree to which PET studies have advanced knowledge and the future role anticipated for PET. All clinical and basic researchers interested in functional imaging with PET and movement disorders will find this book an absolute must.
Download or read book Multimodality Imaging Techniques in PD and Atypical Parkinsonism written by Zachory Wei and published by Frontiers Media SA. This book was released on 2024-02-27 with total page 79 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Quantitative Magnetic Resonance Imaging written by Nicole Seiberlich and published by Academic Press. This book was released on 2020-11-18 with total page 1094 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quantitative Magnetic Resonance Imaging is a ‘go-to’ reference for methods and applications of quantitative magnetic resonance imaging, with specific sections on Relaxometry, Perfusion, and Diffusion. Each section will start with an explanation of the basic techniques for mapping the tissue property in question, including a description of the challenges that arise when using these basic approaches. For properties which can be measured in multiple ways, each of these basic methods will be described in separate chapters. Following the basics, a chapter in each section presents more advanced and recently proposed techniques for quantitative tissue property mapping, with a concluding chapter on clinical applications. The reader will learn: The basic physics behind tissue property mapping How to implement basic pulse sequences for the quantitative measurement of tissue properties The strengths and limitations to the basic and more rapid methods for mapping the magnetic relaxation properties T1, T2, and T2* The pros and cons for different approaches to mapping perfusion The methods of Diffusion-weighted imaging and how this approach can be used to generate diffusion tensor maps and more complex representations of diffusion How flow, magneto-electric tissue property, fat fraction, exchange, elastography, and temperature mapping are performed How fast imaging approaches including parallel imaging, compressed sensing, and Magnetic Resonance Fingerprinting can be used to accelerate or improve tissue property mapping schemes How tissue property mapping is used clinically in different organs Structured to cater for MRI researchers and graduate students with a wide variety of backgrounds Explains basic methods for quantitatively measuring tissue properties with MRI - including T1, T2, perfusion, diffusion, fat and iron fraction, elastography, flow, susceptibility - enabling the implementation of pulse sequences to perform measurements Shows the limitations of the techniques and explains the challenges to the clinical adoption of these traditional methods, presenting the latest research in rapid quantitative imaging which has the possibility to tackle these challenges Each section contains a chapter explaining the basics of novel ideas for quantitative mapping, such as compressed sensing and Magnetic Resonance Fingerprinting-based approaches
Download or read book Functional Magnetic Resonance Imaging Studies of Motion Control in Patients with Movement Disorders written by Cynthia Lily Castillo and published by . This book was released on 1998 with total page 72 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Magnetic Resonance Spectroscopy written by Charlotte Stagg and published by Academic Press. This book was released on 2013-11-11 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetic Resonance Spectroscopy: Tools for Neuroscience Research and Emerging Clinical Applications is the first comprehensive book for non-physicists that addresses the emerging and exciting technique of magnetic resonance spectroscopy. Divided into three sections, this book provides coverage of the key areas of concern for researchers. The first, on how MRS is acquired, provides a comprehensive overview of the techniques, analysis, and pitfalls encountered in MRS; the second, on what can be seen by MRS, provides essential background physiology and biochemistry on the major metabolites studied; the final sections, on why MRS is used, constitutes a detailed guide to the major clinical and scientific uses of MRS, the current state of teh art, and recent innovations. Magnetic Resonance Spectroscopy will become the essential guide for people new to the technique and give those more familiar with MRS a new perspective. Chapters written by world-leading experts in the field Fully illustrated Covers both proton and non-proton MRS Includes the background to novel MRS imaging approaches
Download or read book Neuropathology of Neurodegenerative Diseases written by Gabor G. Kovacs and published by Cambridge University Press. This book was released on 2017-12-13 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical guide to the diagnosis of neurodegenerative diseases discusses modern molecular techniques, morphological classification, fundamentals of clinical symptomology, diagnostic pitfalls and immunostaining protocols. It is based on the proteinopathy concept of neurodegenerative disease, which has influenced classification and provides new strategies for therapy. Numerous high-quality images, including histopathology photomicrographs and neuroradiology scans, accompany the description of morphologic alterations and interpretation of immunoreactivities. Diagnostic methods and criteria are placed within recent developments in neuropathology, including the now widespread application of immunohistochemistry. To aid daily practice, the guide includes diagnostic algorithms and offers personal insights from experienced experts in the field. Special focus is given to the way brain tissue should be handled during diagnosis. This is a must-have reference for medical specialists and specialist medical trainees in the fields of pathology, neuropathology and neurology working with neuropathologic features of neurodegenerative diseases.
Download or read book Movement Disorder Surgery written by Roy AE Bakay and published by Thieme. This book was released on 2011-01-01 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential reference for state-of-the-art techniques in movement disorder surgery Authored by world renowned experts in neurosurgery and neurology, this book is a comprehensive reference for the entire spectrum of surgical treatments for movement disorders, with an emphasis on the use of deep brain stimulation. It provides essential information on the proposed mechanism of action, electrophysiology, preoperative evaluation, surgical techniques, postoperative care, and anticipated outcomes. High-quality images of anatomy and electrophysiology supplement detailed descriptions of each surgical procedure to ensure that clinicians gain a solid understanding of each clinical problem. The text covers the newest techniques, such as frameless functional stereotactic approaches, and provides critical discussion of the efficacy and possible complications of deep brain stimulation. Features: Complete technical details for performing movement disorder surgery with or without microelectrode recording Practical discussion of a simplified electrical basis for programming deep brain stimulators Information about new directions for deep brain stimulation as well as alternative therapies, such as gene therapy and cellular therapy Guidance on how to avoid and manage potential complications Extensive coverage of anesthesia to help clinicians optimize patient care and comfort Recommendations for setting up a multidisciplinary practice More than 150 high-quality illustrations demonstrating key concepts This essential reference will aid clinicians and residents in neurosurgery, neurology, anesthesiology, and neurophysiology in instituting the best practices for movement disorder surgery.
Download or read book Functional Magnetic Resonance Imaging of Repetitive Movement in Healthy Subjects and Patients with Parkinson s Disease written by Tracy Ann Boyd and published by . This book was released on 2002 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt:
