Download or read book M thodes neuronales dans l analyse de survie written by Quoc Anh Trinh and published by . This book was released on 2007 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: Les réseaux de neurones artificiels sont un outil statistique utile à la prédiction de la survie en médecine clinique qui connaît un certain succès comme en témoigne le numéro spécial de la revue Cancer du 15 avril 2001.Ce travail propose une généralisation des modèles classiques de survie où les variables prédictives linéaires sont remplacées par des variables prédictives non linéaires modélisées par des perceptrons multicouches non récurrents. Cette modélisation dont l'objectif est de prédire un temps de survie prend en compte les effets dépendant du temps et les interactions entre variables. Le modèle des réseaux de neurones permet de s'affranchir des restrictions du modèle de Cox car il peut estimer les effets dépendant du temps ainsi que des interactions éventuelles. En outre, la présence de données censurées, la particularité de l'analyse de survie, donne envie de prendre en compte toutes les connaissances disponibles sur les données pour l'apprentissage des modèles neuronaux afin d'avoir un meilleur modèle prédictif. L'approche bayésienne est donc une approche appropriée car elle permet une meilleure généralisation des réseaux pendant la phase d' apprentissage en évitant le sur-ajustement qui peut se produire au cours de l'apprentissage avec l'algorithme de rétro-propagation. De plus, un apprentissage bayésien hiérarchise des réseaux de neurones convient parfaitement à une sélection de variables pertinentes qui permet une meilleure explication des effets dépendant du temps et des interactions entre variables. La performance des approches à base d'apprentissage de réseaux de neurones dans l'analyse de survie dépend notamment de la taille de l'ensemble des données d'apprentissage et du taux de censure de données. En particulier, pour les données de génomes pour lesquelles les variables sont beaucoup plus nombreuses que les observations, une sélection des variables importantes peut être effectuée par des réseaux de neurones après une sélection automatique des variables pertinentes pour diminuer la dimension de l'espace des données. Une estimation plus précise du temps de survie permet une meilleure connaissance physiopathologique de la maladie et une meilleure stratégie thérapeutique. Celle-ci est obtenue grâce à la méthode de ré-échantillonnage de données et à l'adaptativité du modèle neuronal. La construction d'un arbre de décision sur des estimations du réseau permet une meilleure définition des groupes pronostiques de survie
Download or read book Evolution of the Forebrain written by R.G. Hassler and published by Springer. This book was released on 2013-12-11 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book New Strategies in Locust Control written by S. Krall and published by Birkhäuser. This book was released on 2012-12-06 with total page 487 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the late eighties large-scale control operations were carried out to control a major desert locust upsurge in Africa. For the first time since the banning of organochlorine pesticides these operations relied mainly on non-persistent pesticides such as organophosphates and pyrethroids. The amount of pesticides sprayed and the area covered were probably the highest in the history of locust control and raised criticism with respect to efficacy, economic viability and environmental impact. As a consequence, applied research into the problem was intensified, both at the national and the international level, with the goal of finding new and environmentally sound approaches and solutions to locust and grasshopper control. Emphasis was laid on developing new control agents and techniques.
Download or read book Statistical Inference for Ergodic Diffusion Processes written by Yury A. Kutoyants and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 493 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first book in inference for stochastic processes from a statistical, rather than a probabilistic, perspective. It provides a systematic exposition of theoretical results from over ten years of mathematical literature and presents, for the first time in book form, many new techniques and approaches.
Download or read book Semiparametric Theory and Missing Data written by Anastasios Tsiatis and published by Springer Science & Business Media. This book was released on 2007-01-15 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes current knowledge regarding the theory of estimation for semiparametric models with missing data, in an organized and comprehensive manner. It starts with the study of semiparametric methods when there are no missing data. The description of the theory of estimation for semiparametric models is both rigorous and intuitive, relying on geometric ideas to reinforce the intuition and understanding of the theory. These methods are then applied to problems with missing, censored, and coarsened data with the goal of deriving estimators that are as robust and efficient as possible.
Download or read book Your Mindful Compass written by Andrea Maloney Schara and published by . This book was released on 2013-12-01 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Your Mindful Compass" takes us behind the emotional curtain to see the mechanisms regulating individuals in social systems. There is great comfort and wisdom in knowing we can increase our awareness to manage the swift and ancient mechanisms of social control. We can gain greater flexibility by seeing how social controls work in systems from ants to humans. To be less controlled by others, we learn how emotional systems influence our relationship-oriented brain. People want to know what goes on in families that give rise to amazing leaders and/or terrorists. For the first time in history we can understand the systems in which we live. The social sciences have been accumulating knowledge since the early fifties as to how we are regulated by others. S. Milgram, S. Ashe, P. Zimbardo and J. Calhoun, detail the vulnerability to being duped and deceived and the difficulty of cooperating when values differ. Murray Bowen, M.D., the first researcher to observe several live-in families, for up to three years, at the National Institute of Mental Health. Describing how family members overly influence one another and distribute stress unevenly, Bowen described both how symptoms and family leaders emerge in highly stressed families. Our brain is not organized to automatically perceive that each family has an emotional system, fine-tuned by evolution and "valuing" its survival as a whole, as much as the survival of any individual. It is easier to see this emotional system function in ants or mice but not in humans. The emotional system is organized to snooker us humans: encouraging us to take sides, run away from others, to pressure others, to get sick, to blame others, and to have great difficulty in seeing our part in problems. It is hard to see that we become anxious, stressed out and even that we are difficult to deal with. But "thinking systems" can open the doors of perception, allowing us to experience the world in a different way. This book offers both coaching ideas and stories from leaders as to strategies to break out from social control by de-triangling, using paradoxes, reversals and other types of interruptions of highly linked emotional processes. Time is needed to think clearly about the automatic nature of the two against one triangle. Time and experience is required as we learn strategies to put two people together and get self outside the control of the system. In addition, it takes time to clarify and define one's principles, to know what "I" will or will not do and to be able to take a stand with others with whom we are very involved. The good news is that systems' thinking is possible for anyone. It is always possible for an individual to understand feelings and to integrate them with their more rational brains. In so doing, an individual increases his or her ability to communicate despite misunderstandings or even rejection from important others. The effort involved in creating your Mindful Compass enables us to perceive the relationship system without experiencing it's threats. The four points on the Mindful Compass are: 1) Action for Self, 2) Resistance to Forward Progress, 3) Knowledge of Social Systems and the 4) The Ability to Stand Alone. Each gives us a view of the process one enters when making an effort to define a self and build an emotional backbone. It is not easy to find our way through the social jungle. The ability to know emotional systems well enough to take a position for self and to become more differentiated is part of the natural way humans cope with pressure. Now people can use available knowledge to build an emotional backbone, by thoughtfully altering their part in the relationship system. No one knows how far one can go by making an effort to be more of a self-defined individual in relationships to others. Through increasing emotional maturity, we can find greater individual freedom at the same time that we increase our ability to cooperate and to be close to others.
Download or read book Animal Camouflage written by Martin Stevens and published by Cambridge University Press. This book was released on 2011-07-07 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last decade, research on the previously dormant field of camouflage has advanced rapidly, with numerous studies challenging traditional concepts, investigating previously untested theories and incorporating a greater appreciation of the visual and cognitive systems of the observer. Using studies of both real animals and artificial systems, this book synthesises the current state of play in camouflage research and understanding. It introduces the different types of camouflage and how they work, including background matching, disruptive coloration and obliterative shading. It also demonstrates the methodologies used to study them and discusses how camouflage relates to other subjects, particularly with regard to what it can tell us about visual perception. The mixture of primary research and reviews shows students and researchers where the field currently stands and where exciting and important problems remain to be solved, illustrating how the study of camouflage is likely to progress in the future.
Download or read book Medical Image Computing and Computer Assisted Intervention MICCAI 2012 written by Nicholas Ayache and published by Springer. This book was released on 2012-08-28 with total page 645 pages. Available in PDF, EPUB and Kindle. Book excerpt: The three-volume set LNCS 7510, 7511, and 7512 constitutes the refereed proceedings of the 15th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2012, held in Nice, France, in October 2012. Based on rigorous peer reviews, the program committee carefully selected 252 revised papers from 781 submissions for presentation in three volumes. The third volume includes 79 papers organized in topical sections on diffusion imaging: from acquisition to tractography; image acquisition, segmentation and recognition; image registration; neuroimage analysis; analysis of microscopic and optical images; image segmentation; diffusion weighted imaging; computer-aided diagnosis and planning; and microscopic image analysis.
Download or read book The Neganthropocene written by Daniel Ross and published by Saint Philip Street Press. This book was released on 2020-10-09 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the essays and lectures here titled Neganthropocene, Stiegler opens an entirely new front moving beyond the dead-end "banality" of the Anthropocene. Stiegler stakes out a battleplan to proceed beyond, indeed shrugging off, the fulfillment of nihilism that the era of climate chaos ushers in. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.
Download or read book Brain Mind and Developmental Psychopathology in Childhood written by M. Elena Garralda and published by Jason Aronson. This book was released on 2012 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain, Mind, and Developmental Psychopathology in Childhood, part of the International Association of Child and Adolescent Psychiatry and Allied Professions' book series "Working with Children & Adolescents" edited by Elena Garralda and Jean-Philippe Raynaud, aims to help advance knowledge on the connections between brain, mind, and development psychopathology in children and young people, an area of high relevance across different contexts around the world. It outlines brain mechanisms underlying children's ability to regulate behavior, emotions, interactions with others, responses to stress, and child psychiatric disorders. The book contains expert views supported by empirical evidence, and there is an emphasis on drawing out the clinical implications. It brings together knowledge from a variety of disciplines on bodily and brain processes that underlie developmental and psychiatric disorders in children and young people. Chapters include conceptual and empirical discussion of the biological and psychological influences on developmental psychopathology in childhood, clinical updates focusing on the biological underpinnings of individual child neuropsychiatric disorders as well as integrating biological and psychological therapies in child mental health. The book also discusses broader psychological/social problems, with chapters on the effects of child maltreatment in the developing brain, an update on understanding and management of self-harm, and advocacy papers on learning disorders and child and adolescent mental health.
Download or read book Oogenesis written by Marie-Helene Verlhac and published by John Wiley & Sons. This book was released on 2010-03-04 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oogenesis - the process by which female germ cells develop into mature eggs, or ova - is a complex process involving many important elements of developmental and cellular biology: from cell-cell interactions, complex signalling cascades, specialized cell cycles and cytoskeleton organization. Oocytes from various species (including clam, starfish, xenopus and mouse) are excellent model systems to study the biochemistry of cell division with important implications for basic and clinical research. This book describes the entire process of oogenesis in chronological order with contributions from leading international researchers and chapters covering medical and ethical considerations in oogenic biology. Topics include sex determination and gonadal development, control of meiotic chromosome pairing and homologous recombination, control of meiotic divisions and the remodelling of the oocyte into a totipotent zygote as well as medically-assisted reproduction. This volume is an essential resource for all students, researchers and clinicians in developmental and reproductive biology. Key features: Reaches beyond the study of simply meiosis to cover all aspects of oogenesis Synthesizes recent advances in the field, drawing on studies from different model species Chapter sequence designed to follow the time line in vivo Written by an international panel of expert researchers
Download or read book Handbook of GC MS written by Hans-Joachim Hubschmann and published by John Wiley & Sons. This book was released on 2015-07-27 with total page 884 pages. Available in PDF, EPUB and Kindle. Book excerpt: The only comprehensive reference on this popular and rapidly developing technique provides a detailed overview, ranging from fundamentals to applications, including a section on the evaluation of GC-MS analyses. As such, it covers all aspects, including the theory and principles, as well as a broad range of real-life examples taken from laboratories in environmental, food, pharmaceutical and clinical analysis. It also features a glossary of approximately 300 terms and a substance index that facilitates finding a specific application. The first two editions were very well received, making this handbook a must-have in all analytical laboratories using GC-MS.
Download or read book Philosophy in a Time of Terror written by Giovanna Borradori and published by University of Chicago Press. This book was released on 2013-05-28 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: The idea for Philosophy in a Time of Terror was born hours after the attacks on 9/11 and was realized just weeks later when Giovanna Borradori sat down with Jürgen Habermas and Jacques Derrida in New York City, in separate interviews, to evaluate the significance of the most destructive terrorist act ever perpetrated. This book marks an unprecedented encounter between two of the most influential thinkers of our age as here, for the first time, Habermas and Derrida overcome their mutual antagonism and agree to appear side by side. As the two philosophers disassemble and reassemble what we think we know about terrorism, they break from the familiar social and political rhetoric increasingly polarized between good and evil. In this process, we watch two of the greatest intellects of the century at work.
Download or read book Pandex Current Index to Scientific and Technical Literature written by and published by . This book was released on 1971 with total page 1104 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Psychoanalysis and Neuroscience written by Mauro Mancia and published by Springer Science & Business Media. This book was released on 2007-04-29 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent scientific studies have brought significant advances in the understanding of basic mental functions such as memory, dreams, identification, repression, which constitute the basis of the psychoanalytical theory. This book focuses on the possibility of interactions between psychoanalysis and neuroscience: emotions and the right hemisphere, serotonin and depression. It is a unique tool for professionals and students in these fields, and for operators of allied disciplines, such as psychology and psychotherapy.
Download or read book Homo Symbolicus written by Christopher S. Henshilwood and published by John Benjamins Publishing. This book was released on 2011-11-16 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: The emergence of symbolic culture, classically identified with the European cave paintings of the Ice Age, is now seen, in the light of recent groundbreaking discoveries, as a complex nonlinear process taking root in a remote past and in different regions of the planet. In this book the archaeologists responsible for some of these new discoveries, flanked by ethologists interested in primate cognition and cultural transmission, evolutionary psychologists modelling the emergence of metarepresentations, as well as biologists, philosophers, neuro-scientists and an astronomer combine their research findings. Their results call into question our very conception of human nature and animal behaviour, and they create epistemological bridges between disciplines that build the foundations for a novel vision of our lineage's cultural trajectory and the processes that have led to the emergence of human societies as we know them.
Download or read book Environmental Hygiene II written by Norbert H. Seemayer and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: Environmental Hygiene II deals with the evaluation of environmental pollutants and their relevance to human health. Main topics include mutagenic and carcinogenic activity of environmental chemicals, specific effects of heavy metals, special biological indicators for screening environmental contaminants and monitoring of indoor/outdoor air pollutants. Furthermore, assessment of exposure to environmental and occupational chemicals in man are presented as well as epidemiological studies on the health effects by environmental pollution, studies of inhalation toxicology and strategies and policy of environmental control.
