Download or read book na written by Andreas Reichenbach and published by Springer Science & Business Media. This book was released on 2011-02-18 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: Müller cells make up just 0.005% of the cells in our central nervous system. They do not belong to the more esteemed family of neuronal cells but to the glia, a family of cells that until recently were seen as mere filling material between the neurons. Now, however, all that has changed. Sharing the insights of more than a quarter century of research into Müller cells, Drs. Andreas Reichenbach and Andreas Bringmann of Leipzig University make a compelling case for the central role Müller cells play. Everyone agrees that the eye is a very special and versatile sense organ, yet it has turned out in recent years that Müller cells are peculiar and multipotent glial cells. In the retina of most vertebrates and even of many mammals, Müller cells are the only type of (macro- ) glial cells; thus, they are responsible for a wealth of neuron-supportive functions that, in the brain, rely upon a division of labour among astrocytes, oligodendrocytes, and ependymal cells. Even beyond such a role in the central nervous system as "model glia", Müller cells are adapted to several exciting roles in support of vision. They deliver the light stimuli to the photoreceptor cells in the inverted vertebrate retina, aid the processing of visual information, and are responsible for the homeostatic maintenance of the retinal extracellular milieu. In Müller Cells in the Healthy and Diseased Retina, aimed not just at neurobiologists but at anyone concerned with retinal degeneration, every angle of Müller cells is covered, from an introduction to their basic properties, through their roles as 'light cables' and 'shock absorbers', to the part they play in diseases and disorders of the eye. Once these have all been covered in detail, the authors move on to discuss the future direction of research into these small but potent cellular phenomena. About the Authors Dr. Andreas Reichenbach was born in 1950 in Leipzig, Germany. He studied medicine and specialized as a physiologist, working on the mammalian retina. Since 1984, he has focused his efforts - and those of a growing number of fellows in his team - on Müller cell research. He has held a professorship at Leipzig University since 1994. After studying biology, Dr. Andreas Bringmann (* 1960) worked in the field of systemic neurophysiology until he was inspired in 1996 by Andreas Reichenbach to research the most interesting cell, the Müller cell. He is now in the Department of Ophthalmology of the University of Leipzig where he is the head of the Basic Research Laboratory
Download or read book M ller Cells in the Healthy and Diseased Retina written by Andreas Reichenbach and published by Springer. This book was released on 2010-03-18 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: Müller cells may be used in the future for novel therapeutic strategies to protect neurons against apoptosis (for example, somatic gene therapy), or to differentiate retinal neurons from Müller/stem cells. Meanwhile, a proper understanding of the gliotic responses of Müller cells in the diseased retina, and of their protective vs. detrimental effects, is essential for the development of efficient therapeutic strategies that use and stimulate the neuron-supportive/-protective - and prevent the destructive - mechanisms of gliosis.
Download or read book The Retinal M ller Cell written by Vijay Sarthy and published by Springer Science & Business Media. This book was released on 2001-04-30 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph examines the role of the Müller cell, the main glial element of the retina, in the development, organization, and function of the vertebrate retina. These cells may also play a role in the control of eye growth and in determining the processing of information by surrounding neurons.
Download or read book The Retina in Health and Disease written by Maurice Ptito and published by Mdpi AG. This book was released on 2021-12-27 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vision is the most important sense in higher mammals. The retina is the first step in visual processing and the window to the brain. It is not surprising that problems arising in the retina lead to moderate to severe visual impairments. We offer here a collection of reviews as well as original papers dealing with various aspects of retinal function as well as dysfunction. New approaches in retinal research are described, such as the expression and localization of the endocannabinoid system in the normal retina and the role of cannabinoid receptors that could offer new avenues of research in the development of potential treatments for retinal diseases. Moreover, new insights are offered in advancing knowledge towards the prevention and cure of visual pathologies, mainly AMD, RP, and diabetic retinopathy.
Download or read book Collagens and Retinal M ller Cells in Healthy and Diseased Vitreoretinal Interface written by Rijksuniversiteit Groningen and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Retinal Muller Cell written by Vijay Sarthy and published by . This book was released on 2014-09-01 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Webvision written by Helga Kolb and published by . This book was released on 2007 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Fovea written by Andreas Bringmann and published by Academic Press. This book was released on 2021-08-28 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Fovea: Structure, Function, Development, and Disease summarizes the current biological knowledge regarding the two types of the vertebrate fovea (and its main structural elements, the Müller cells). This information is then used to explain different aspects of human vision, foveal development, and macular disorders. Sections give an overview of the retinal structure and the different types of retinal glia, survey the structure and function of the primate and non-mammalian fovea types, discuss foveal development—with a focus on the human fovea, cover the roles of Müller cells and astrocytes in the pathogenesis and regeneration of various human macular disorders are described. Using a translational approach, this reference is a valuable text for scientists, clinicians and physicians interested in the fovea. Readers will gain a new understanding of the cellular basics of the fovea, which is the most important part of the eye. Adopts a translational approach, summarizing the biological knowledge regarding the structure and function of the fovea, the roles of Müller cells in mediating the structural integrity, and function of the fovea Provides overviews of both basic types of the vertebrate fovea, countering the popular belief that there is only one type of the vertebrate fovea, the human fovea Thoroughly shows the mechanisms involved in the development of the fovea that explain the rapid improvement of visual acuity in newborns Explains pathological changes in the foveal structure and function with evaluation pointing toward possible prevention and/or cure
Download or read book Textbook of Vascular Medicine written by Rhian M. Touyz and published by Springer. This book was released on 2019-08-02 with total page 503 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook focuses on the vascular biology and physiology that underlie vascular disorders in clinical medicine. Vascular biomedicine is a rapidly growing field as new molecular mechanisms of vascular health and disease are unraveled. Many of the major cardiovascular diseases including coronary artery disease, heart failure, stroke and vascular dementia are diseases of the vasculature. In addition vascular injury underpins conditions like kidney failure and cardiovascular complications of diabetes. This field is truly multidisciplinary involving scientists in many domains such as molecular and vascular biology, cardiovascular physiology and pharmacology and immunology and inflammation. Clinically, specialists across multiple disciplines are involved in the management of patients with vascular disorders, including cardiologists, nephrologists, endocrinologists, neurologists and vascular surgeons. This book covers a wide range of topics and provides an overview of the discipline of vascular biomedicine without aiming at in-depth reviews, but rather offering up-to-date knowledge organized in concise and structured chapters, with key points and pertinent references. The structure of the content provides an integrative and translational approach from basic science (e.g. stem cells) to clinical medicine (e.g. cardiovascular disease). The content of this book is targeted to those who are new in the field of vascular biology and vascular medicine and is ideal for medical students, graduate and postgraduate students, clinical fellows and academic clinicians with an interest in the vascular biology and physiology of cardiovascular disease and related pathologies.
Download or read book Vitreous written by J. Sebag and published by Springer. This book was released on 2014-10-01 with total page 917 pages. Available in PDF, EPUB and Kindle. Book excerpt: The vitreous body long has been the most mysterious of all ocular structures, owing perhaps to its seeming simplicity. There have been few concerted, sustained efforts to unravel the mysteries of how vitreous is composed and what role it plays in normal physiology as well as pathology. Over the years, however, many studies have produced important findings concerning vitreous biochemistry, structure, physiology, and pathobiology. Published on the 25th anniversary of Sebag's first book on Vitreous, this second installment is nearly five times longer than its predecessor, reflecting how much has been learned in the past quarter century. This well-constructed compendium not only addresses the most current scientific knowledge, but also reviews clinical perspectives in a manner that lends richness to the scope of the book. Written by 90 authors, this book has 56 chapters organized into 7 sections: Biochemistry; Anatomy, Development, and Aging; Pathology/Pathobiology; Physiology and Phamacotherapy; Posterior Vitreo-Retinal Surgery; Peripheral Vitreo-Retinal Surgery; and Pharmacologic Vitreolysis. With a foreword by Coleman & Lincoff and an introduction by Wallace Foulds, Sebag's latest tome on vitreous is destined to be the authoritative text for years to come.
Download or read book Cell Based Therapy for Degenerative Retinal Disease written by Marco A. Zarbin and published by Springer. This book was released on 2019-03-01 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses why specific diseases are being targeted for cell-based retinal therapy, what evidence exists that justifies optimism for this approach, and what challenges must be managed in order to bring this technology from the laboratory into routine clinical practice. There are a number of unanswered questions (e.g., surgical approach to cell delivery, management of immune response, optimum cell type to transplant) that very likely are not going to be answered until human trials are undertaken, but there is a certain amount of “de-risking” that can be done with preclinical experimentation. This book is essential reading for scientists, clinicians, and advanced students in stem cell research, cell biology, and ophthalmology.
Download or read book Principles and Practice of Clinical Electrophysiology of Vision second edition written by John R. Heckenlively and published by MIT Press. This book was released on 2006-04-07 with total page 1033 pages. Available in PDF, EPUB and Kindle. Book excerpt: The long-awaited second edition of an authoritative reference on electrophysiologic vision testing, including detailed information on techniques and problems, basic physiology and anatomy, theoretical concepts, and clinical findings; with extensive new material. This authoritative text is the only comprehensive reference available on electrophysiologic vision testing, offering both practical information on techniques and problems as well as basic physiology and anatomy, theoretical concepts, and clinical correlations. The second edition, of the widely used text, offers extensive new material and updated information: 65 of the 84 chapters are completely new, with the changes reflecting recent advances in the field. The book will continue to be an essential resource for practitioners and scholars from a range of disciplines within vision science. The contributions not only cover new information—important material that is likely to become more important in the next decade—but also offer a long-range perspective on the field and its remarkable development in the last century. After discussing the history and background of clinical electrophysiology, the book introduces the anatomy of the retina and principles of cell biology in the visual pathways at the molecular, physiological, and biochemical levels. It relates these new findings to the techniques and interpretations of clinical tests, including the electro-oculogram (EOG), electroretinogram (ERG), and visual evoked potentials (VEP), which are discussed in detail, as are equipment, data acquisition and analysis, principles and protocols for clinical testing, diseases and dysfunction, and animal testing. Notable additions for this edition include chapters on the origin of electroretinogram waveforms, multifocal techniques, testing in standard laboratory animals, recent advances in analysis of abnormalities in disease, and the applications of these techniques to the study of genetic abnormalities.
Download or read book Glial Cells written by Peter R. Laming and published by Cambridge University Press. This book was released on 1998-06-28 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: This 1998 book discusses how neurons and glial cells interact with each other to influence behaviour.
Download or read book Cell Cell Interactions Controlling Neuronal Functionality in Health and Disease written by Stefano Angiari and published by Frontiers Media SA. This book was released on 2022-07-27 with total page 141 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Patterning and Cell Type Specification in the Developing CNS and PNS written by and published by Academic Press. This book was released on 2013-05-06 with total page 993 pages. Available in PDF, EPUB and Kindle. Book excerpt: The genetic, molecular, and cellular mechanisms of neural development are essential for understanding evolution and disorders of neural systems. Recent advances in genetic, molecular, and cell biological methods have generated a massive increase in new information, but there is a paucity of comprehensive and up-to-date syntheses, references, and historical perspectives on this important subject. The Comprehensive Developmental Neuroscience series is designed to fill this gap, offering the most thorough coverage of this field on the market today and addressing all aspects of how the nervous system and its components develop. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurological treatments being developed based on our increased understanding of developmental mechanisms. Each volume in the series consists of review style articles that average 15-20pp and feature numerous illustrations and full references. Volume 1 offers 48 high level articles devoted mainly to patterning and cell type specification in the developing central and peripheral nervous systems. Series offers 144 articles for 2904 full color pages addressing ways in which the nervous system and its components develop Features leading experts in various subfields as Section Editors and article Authors All articles peer reviewed by Section Editors to ensure accuracy, thoroughness, and scholarship Volume 1 sections include coverage of mechanisms which: control regional specification, regulate proliferation of neuronal progenitors and control differentiation and survival of specific neuronal subtypes, and controlling development of non-neural cells
Download or read book Pituitary Adenylate Cyclase Activating Polypeptide written by Hubert Vaudry and published by Springer Science & Business Media. This book was released on 2003 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pituitary Adenylate Cyclase-Activating Polypeptide is the first volume to be written on the neuropeptide PACAP. It covers all domains of PACAP from molecular and cellular aspects to physiological activities and promises for new therapeutic strategies. Pituitary Adenylate Cyclase-Activating Polypeptide is the twentieth volume published in the Endocrine Updates book series under the Series Editorship of Shlomo Melmed, MD.
Download or read book Evolving Human Nutrition written by Stanley J. Ulijaszek and published by Cambridge University Press. This book was released on 2012-10-18 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exploration of changing human nutrition from evolutionary and social perspectives and its influence on health and disease, past and present.
