Download or read book Liquid Chromatography in Clinical Analysis written by Pokar M. Kabra and published by Springer Science & Business Media. This book was released on 2008-02-07 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: Liquid Chromatography in Clinical Analysis

Download or read book Liquid Chromatography in Clinical Analysis written by Pokar M. Kabra and published by . This book was released on 2014-09-01 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Liquid Chromatography in Clinical Analysis written by Pokar M. Kabra and published by Humana Press. This book was released on 2013-11-27 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Chromatographic Methods in Clinical Chemistry and Toxicology written by Roger Bertholf and published by John Wiley & Sons. This book was released on 2007-01-30 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to fill the gap that exists between theoretical treatments of chromatography, and clinical chemistry and toxicology texts, which focus almost exclusively on clinical relevance and applications. Chromatography has a vast array of clinical applications, and though the chromatographic methods were first introduced decades ago, new applications of this technology are being used to explore previously inaccessible frontiers in clinical diagnostics and toxicological testing. An up-to-date book devoted to clinical and toxicological applications of chromatographic methods will serve as an instructional and reference text, useful to students, laboratory technicians, and researchers.

Download or read book HPLC in Clinical Chemistry written by Papadoyannis and published by CRC Press. This book was released on 1990-06-19 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on the use of high-performance liquid chromatography (HPLC) as a means to assess quantities of separated components in HPLC detectors, this volume is structured for use by analysts who have some experience in chemical analysis or have done HPLC. It keeps theory and instrumentation at a minimum

Download or read book Mass Spectrometry for the Clinical Laboratory written by Hari Nair and published by Academic Press. This book was released on 2016-11-02 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mass Spectrometry for the Clinical Laboratory is an accessible guide to mass spectrometry and the development, validation, and implementation of the most common assays seen in clinical labs. It provides readers with practical examples for assay development, and experimental design for validation to meet CLIA requirements, appropriate interference testing, measuring, validation of ion suppression/matrix effects, and quality control. These tools offer guidance on what type of instrumentation is optimal for each assay, what options are available, and the pros and cons of each. Readers will find a full set of tools that are either directly related to the assay they want to adopt or for an analogous assay they could use as an example. Written by expert users of the most common assays found in a clinical laboratory (clinical chemists, toxicologists, and clinical pathologists practicing mass spectrometry), the book lays out how experts in the field have chosen their mass spectrometers, purchased, installed, validated, and brought them on line for routine testing. The early chapters of the book covers what the practitioners have learned from years of experience, the challenges they have faced, and their recommendations on how to build and validate assays to avoid problems. These chapters also include recommendations for maintaining continuity of quality in testing. The later parts of the book focuses on specific types of assays (therapeutic drugs, Vitamin D, hormones, etc.). Each chapter in this section has been written by an expert practitioner of an assay that is currently running in his or her clinical lab. Provides readers with the keys to choosing, installing, and validating a mass spectrometry platform Offers tools to evaluate, validate, and troubleshoot the most common assays seen in clinical pathology labs Explains validation, ion suppression, interference testing, and quality control design to the detail that is required for implementation in the lab

Download or read book Liquid Chromatography written by G. Baird and published by Elsevier Inc. Chapters. This book was released on 2013-01-08 with total page 32 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical chemistry is the discipline within laboratory medicine concerned with measuring the concentrations of analytes in blood, body fluids, and tissues. Liquid chromatography is already commonly used in the clinical chemistry laboratory for measuring the concentrations of small molecules, such as drugs and hormones, using a variety of solid phases for separation and numerous detection modalities, most important mass spectrometry. Additional liquid chromatographic methods are now being developed for measuring the concentrations of proteins in blood and tissues, taking advantage of the rapid development of novel mass-spectrometry instruments and methodologies.

Download or read book Analytical Techniques for Clinical Chemistry written by Sergio Caroli and published by John Wiley & Sons. This book was released on 2012-06-26 with total page 37 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discover how analytical chemistry supports the latest clinical research This book details the role played by analytical chemistry in fostering clinical research. Readers will discover how a broad range of analytical techniques support all phases of clinical research, from early stages to the implementation of practical applications. Moreover, the contributing authors' careful step-by-step guidance enables readers to better understand standardized techniques and steer clear of everyday problems that can arise in the lab. Analytical Techniques for Clinical Chemistry opens with an overview of the legal and regulatory framework governing clinical lab analysis. Next, it details the latest progress in instrumentation and applications in such fields as biomonitoring, diagnostics, food quality, biomarkers, pharmaceuticals, and forensics. Comprised of twenty-five chapters divided into three sections exploring Fundamentals, Selected Applications, and Future Trends, the book covers such critical topics as: Uncertainty in clinical chemistry measurements Metal toxicology in clinical, forensic, and chemical pathology Role of analytical chemistry in the safety of drug therapy Atomic spectrometric techniques for the analysis of clinical samples Biosensors for drug analysis Use of X-ray techniques in medical research Each chapter is written by one or more leading pioneers and experts in analytical chemistry. Contributions are based on a thorough review and analysis of the current literature as well as the authors' own firsthand experiences in the lab. References at the end of each chapter serve as a gateway to the literature, enabling readers to explore individual topics in greater depth. Presenting the latest achievements and challenges in the field, Analytical Techniques for Clinical Chemistry sets the foundation for future advances in laboratory research techniques.

Download or read book Clinical Applications of Mass Spectrometry in Drug Analysis written by Uttam Garg and published by Springer Nature. This book was released on 2023-11-30 with total page 469 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fully updated volume describes methods and protocols for a number of drugs and toxins in a stepwise manner. Exploring the versatility and flexibility of mass spectrometry, the book covers the advantages of this technology, which typically include elimination of the need for special reagents such as antibodies, increased sensitivity and specificity, and multi-component analysis enabling the screening of tens to hundreds of compounds in a single assay run. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Clinical Applications of Mass Spectrometry in Drug Analysis: Methods and Protocols, Second Edition serves as a valuable resource for laboratory professionals who are already utilizing mass spectrometry or considering bringing this technology to their labs.

Download or read book Clinical Applications of Mass Spectrometry in Biomolecular Analysis written by Uttam Garg and published by Humana. This book was released on 2015-11-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides stepwise instructions for the analysis of numerous clinically important analytes by mass spectrometry. Mass spectrometry offers clinical laboratory scientists a number of advantages including increased sensitivity and specificity, multiple component analysis, and no need for specialized reagents. The techniques described are a must for the measurement of many clinically relevant analytes in the fields of drug analysis, endocrinology, and inborn errors of metabolism. Each chapter provides a brief introduction about a specified analyte, followed by detailed instructions on the analytical protocol. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting edge and practical, Clinical Applications of Mass Spectrometry in Biomolecular Analysis: Methods and Protocols is a great resource for clinical laboratory scientists who are already using or thinking of bringing mass spectrometry to their laboratories.

Download or read book New Developments in Clinical Instrumentation written by Leroy Hersh and published by CRC Press. This book was released on 2018-01-18 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book has information regarding the new developments in clinical instrumentation, focusing on fluorometers and densitometers, explaining the principles, the use of high performance liquid chromatography in clinical laboratories. Automated Microbiology; dabbling into detection, light scanning and analysis of particles. Amore recent aspect of automation has been, made possible by the advent of the microprocessor orcomputer-on-a-chip. The development of miniature, inexpensive micro-computers has resulted in the automation for relatively sophisticated processes. The two aspects of automation are represented in this monograph. The automated control of physical processes, and automation of the information processing. There are elements of both aspects of automation in this book. The areas discussed do emphasize more or less strongly either tight automated control of physical processes or automation of information processing. They all represent the attempt of medical technology to yield more precise, accurate, less expensive and faster to acid in the clinical diagnosis.

Download or read book Clinical analysis written by Steven H. Y. Wong and published by . This book was released on 1992 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Therapeutic Drug Monitoring and Toxicology by Liquid Chromatography written by Steven H.Y. Wong and published by Routledge. This book was released on 2017-09-19 with total page 521 pages. Available in PDF, EPUB and Kindle. Book excerpt: This important, new reference provides the first , up-to-date, and comprehensive treatmentof the various liquid chromatography (LC) instrumentation for Therapeutic DrugMonitoring (TDM) and toxicology drug assays and reviews the clinical pharmacologyof major classes of drugs and their LC analyses.Written by authoritative contributors who bring many years of personal laboratory/clinical experience to the book, this interdisciplinary work : presents the principlesof TDM, sampling techniques, and various instrumentation topics, including computerinterfacing, mass spectrometry, fluorescence , electrochemical detection, and bloodcollection devices . .. examines six primary classes of drugs, complete with recommendedLC procedures and emphasizing recently introduced drugs and their LC analyses. .. and documents medicolegal guidelines and laboratory management considerations,providing a contemporary assessment of today's laboratory needs.The only practical, current guide available on the subject, Therapeutic Drug Monitoringand Toxicology by Li([uid Chromatography belongs in the personal libraries of clinicaland analytical chemists and biochemists, clinical pharmacologists, clinical toxicologists,clinical pathologists, immunologists, liquid chromatographers, mass spectroscopists, laboratorydirectors, laboratory instrument manufacturers , and medical technologists. Thebook is also vital supplementary reading for advanced undergraduate and graduate-levelclinical chemistry, toxicology, clinical pathology, and liquid chromatography course.

Download or read book Principles and Applications of Clinical Mass Spectrometry written by Nader Rifai and published by Elsevier. This book was released on 2018-06-26 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles and Applications of Clinical Mass Spectrometry: Small Molecules, Peptides, and Pathogens is a concise resource for quick implementation of mass spectrometry methods in clinical laboratory work. Focusing on the practical use of these techniques, the first half of the book covers principles of chromatographic separations, principles and types of mass spectrometers, and sample preparation for analysis; the second half outlines the main applications of this technology within clinical laboratory settings, including determination of small molecules and peptides, as well as pathogen identification. A thorough yet succinct guide to using mass spectrometry technology in the clinical laboratory, Principles and Applications of Clinical Mass Spectrometry: Small Molecules, Peptides, and Pathogens is an essential resource for chemists, pharmaceutical and biotech researchers, certain government agencies, and standardization groups. - Provides concrete examples of the main applications of mass spectrometry technology - Describes current capabilities of the LC- and MS-based analytical methods - Details methods for successful analytical work in the field

Download or read book Clinical Liquid Chromatography CRC Volume II Analysis of Endogenous Compounds written by PM Kabra (Ed) and published by . This book was released on 1984 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book High Performance Liquid Chromatography in Phytochemical Analysis written by Monika Waksmundzka-Hajnos and published by CRC Press. This book was released on 2010-11-08 with total page 996 pages. Available in PDF, EPUB and Kindle. Book excerpt: The powerful, efficient technique of high performance liquid chromatography (HPLC) is essential to the standardization of plant-based drugs, identification of plant material, and creation of new herbal medicines. Filling the void in this critical area, High Performance Liquid Chromatography in Phytochemical Analysis is the first book to give a comp

Download or read book LC MS in Drug Bioanalysis written by Q. Alan Xu and published by Springer Science & Business Media. This book was released on 2012-07-15 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical pharmacology plays an important role in today’s medicine. Due to the high sensitivity, selectivity, and affordability of a mass spectrometer (MS), the high performance liquid chromatography – mass spectrometry (LC-MS) analytical technique is widely used in the determination of drugs in human biological matrixes for clinical pharmacology. Specifically, LC-MS is used to analyze: anticancer drugs antidementia drugs antidepressant drugs antiepileptic drugs antifundal drug antimicrobial drugs antipsychotic drugs antiretroviral drugs anxiolytic/hypnotic drugs cardiac drugs drugs for addiction immunosuppressant drugs mood stabilizer drugs This book will primarily cover the various methods of validation for LC-MS techniques and applications used in modern clinical pharmacology.