Download or read book Data Analysis for the Life Sciences with R written by Rafael A. Irizarry and published by CRC Press. This book was released on 2016-10-04 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers several of the statistical concepts and data analytic skills needed to succeed in data-driven life science research. The authors proceed from relatively basic concepts related to computed p-values to advanced topics related to analyzing highthroughput data. They include the R code that performs this analysis and connect the lines of code to the statistical and mathematical concepts explained.
Download or read book Deep Learning for the Life Sciences written by Bharath Ramsundar and published by O'Reilly Media. This book was released on 2019-04-10 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Deep learning has already achieved remarkable results in many fields. Now it’s making waves throughout the sciences broadly and the life sciences in particular. This practical book teaches developers and scientists how to use deep learning for genomics, chemistry, biophysics, microscopy, medical analysis, and other fields. Ideal for practicing developers and scientists ready to apply their skills to scientific applications such as biology, genetics, and drug discovery, this book introduces several deep network primitives. You’ll follow a case study on the problem of designing new therapeutics that ties together physics, chemistry, biology, and medicine—an example that represents one of science’s greatest challenges. Learn the basics of performing machine learning on molecular data Understand why deep learning is a powerful tool for genetics and genomics Apply deep learning to understand biophysical systems Get a brief introduction to machine learning with DeepChem Use deep learning to analyze microscopic images Analyze medical scans using deep learning techniques Learn about variational autoencoders and generative adversarial networks Interpret what your model is doing and how it’s working
Download or read book Writing in the Life Sciences written by Laurence S. Greene and published by Oxford University Press, USA. This book was released on 2010-01-01 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: Practicing scientists know that the quality of their livelihood is strongly connected to the quality of their writing, and critical thinking is the most necessary and valuable tool for effectively generating and communicating scientific information. Writing in the Life Sciences is an innovative, process-based text that gives beginning writers the tools to write about science skillfully by taking a critical thinking approach. Laurence Greene emphasizes "writing as thinking" as he takes beginning writers through the important stages of planning, drafting, and revising their work. Throughout, he uses focused and systematic critical reading and thinking activities to help scientific writers develop the skills to effectively communicate. Each chapter addresses a particular writing task rather than a specific type of document. The book makes clear which tasks are important for all writing projects (i.e., audience analysis, attending to instructions) and which are unique to a specific writing project (rhetorical goals for each type of document). Ideal for Scientific Writing courses and writing-intensive courses in various science departments (e.g., Biology, Environmental Studies, etc.), this innovative, process-based text goes beyond explaining what scientific writing is and gives students the tools to do it skillfully.
Download or read book Physics of the Life Sciences written by Jay Newman and published by Springer Science & Business Media. This book was released on 2010-03-23 with total page 721 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each chapter has three types of learning aides for students: open-ended questions, multiple-choice questions, and quantitative problems. There is an average of about 50 per chapter. There are also a number of worked examples in the chapters, averaging over 5 per chapter, and almost 600 photos and line drawings.
Download or read book Dual Use Research of Concern in the Life Sciences written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-10-01 with total page 115 pages. Available in PDF, EPUB and Kindle. Book excerpt: The potential misuse of advances in life sciences research is raising concerns about national security threats. Dual Use Research of Concern in the Life Sciences: Current Issues and Controversies examines the U.S. strategy for reducing biosecurity risks in life sciences research and considers mechanisms that would allow researchers to manage the dissemination of the results of research while mitigating the potential for harm to national security.
Download or read book Global Transformations in the Life Sciences 1945 1980 written by Patrick Manning and published by University of Pittsburgh Press. This book was released on 2018-06-07 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second half of the twentieth century brought extraordinary transformations in knowledge and practice of the life sciences. In an era of decolonization, mass social welfare policies, and the formation of new international institutions such as UNESCO and the WHO, monumental advances were made in both theoretical and practical applications of the life sciences, including the discovery of life’s molecular processes and substantive improvements in global public health and medicine. Combining perspectives from the history of science and world history, this volume examines the impact of major world-historical processes of the postwar period on the evolution of the life sciences. Contributors consider the long-term evolution of scientific practice, research, and innovation across a range of fields and subfields in the life sciences, and in the context of Cold War anxieties and ambitions. Together, they examine how the formation of international organizations and global research programs allowed for transnational exchange and cooperation, but in a period rife with competition and nationalist interests, which influenced dramatic changes in the field as the postcolonial world order unfolded.
Download or read book Model Based Inference in the Life Sciences written by David R. Anderson and published by Springer Science & Business Media. This book was released on 2007-12-22 with total page 203 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook introduces a science philosophy called "information theoretic" based on Kullback-Leibler information theory. It focuses on a science philosophy based on "multiple working hypotheses" and statistical models to represent them. The text is written for people new to the information-theoretic approaches to statistical inference, whether graduate students, post-docs, or professionals. Readers are however expected to have a background in general statistical principles, regression analysis, and some exposure to likelihood methods. This is not an elementary text as it assumes reasonable competence in modeling and parameter estimation.
Download or read book Mathematics for the Life Sciences written by Erin N. Bodine and published by Princeton University Press. This book was released on 2014-08-17 with total page 630 pages. Available in PDF, EPUB and Kindle. Book excerpt: An accessible undergraduate textbook on the essential math concepts used in the life sciences The life sciences deal with a vast array of problems at different spatial, temporal, and organizational scales. The mathematics necessary to describe, model, and analyze these problems is similarly diverse, incorporating quantitative techniques that are rarely taught in standard undergraduate courses. This textbook provides an accessible introduction to these critical mathematical concepts, linking them to biological observation and theory while also presenting the computational tools needed to address problems not readily investigated using mathematics alone. Proven in the classroom and requiring only a background in high school math, Mathematics for the Life Sciences doesn't just focus on calculus as do most other textbooks on the subject. It covers deterministic methods and those that incorporate uncertainty, problems in discrete and continuous time, probability, graphing and data analysis, matrix modeling, difference equations, differential equations, and much more. The book uses MATLAB throughout, explaining how to use it, write code, and connect models to data in examples chosen from across the life sciences. Provides undergraduate life science students with a succinct overview of major mathematical concepts that are essential for modern biology Covers all the major quantitative concepts that national reports have identified as the ideal components of an entry-level course for life science students Provides good background for the MCAT, which now includes data-based and statistical reasoning Explicitly links data and math modeling Includes end-of-chapter homework problems, end-of-unit student projects, and select answers to homework problems Uses MATLAB throughout, and MATLAB m-files with an R supplement are available online Prepares students to read with comprehension the growing quantitative literature across the life sciences A solutions manual for professors and an illustration package is available
Download or read book Valuation in Life Sciences written by Boris Bogdan and published by Springer Science & Business Media. This book was released on 2010-04-19 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: Valuation is a hot topic among life sciences professionals. There is no clear understanding on how to use the different valuation approaches and how to determine input parameters. Some do not value at all, arguing that it is not possible to get realistic and objective numbers out of it. Some claim it to be an art. In the following chapters we will provide the user with a concise val- tion manual, providing transparency and practical insight for all dealing with valuation in life sciences: project and portfolio managers, licensing executives, business developers, technology transfer managers, entrep- neurs, investors, and analysts. The purpose of the book is to explain how to apply discounted cash flow and real options valuation to life sciences p- jects, i.e. to license contracts, patents, and firms. We explain the fun- mentals and the pitfalls with case studies so that the reader is capable of performing the valuations on his own and repeat the theory in the exercises and case studies. The book is structured in five parts: In the first part, the introduction, we discuss the role of the players in the life sciences industry and their p- ticular interests. We describe why valuation is important to them, where they need it, and the current problems to it. The second part deals with the input parameters required for valuation in life sciences, i.e. success rates, costs, peak sales, and timelines.
Download or read book Understanding Metaphors in the Life Sciences written by Andrew S. Reynolds and published by Cambridge University Press. This book was released on 2022-04-28 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduces the diverse roles metaphors play in the life sciences and highlights their significance for theory, communication, and education.
Download or read book Managing Discovery in the Life Sciences written by Philip A. Rea and published by Cambridge University Press. This book was released on 2018-02 with total page 557 pages. Available in PDF, EPUB and Kindle. Book excerpt: Addresses in roughly equal measure the science and management behind several recent marketable biomedical innovations.
Download or read book A History of the Life Sciences written by Lois N. Magner and published by Marcel Dekker. This book was released on 1994 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: A clear and concise survey of the major themes and theories embedded in the history of life science, this book covers the development and significance of scientific methodologies, the relationship between science and society, and the diverse ideologies and current paradigms affecting the evolution and progression of biological studies. The author discusses cell theory, embryology, physiology, microbiology, evolution, genetics, and molecular biology; the Human Genome Project; and genomics and proteomics. Covering the philosophies of ancient civilizations to modern advances in genomics and molecular biology, the book is a unique and comprehensive resource.
Download or read book Energy Research Abstracts written by and published by . This book was released on 1983 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Landscapes of Collectivity in the Life Sciences written by Snait B. Gissis and published by MIT Press. This book was released on 2018-01-12 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: Broad perspective on collectivity in the life sciences, from microorganisms to human consensus, and the theoretical and empirical opportunities and challenges. Many researchers and scholars in the life sciences have become increasingly critical of the traditional methodological focus on the individual. This volume counters such methodological individualism by exploring recent and influential work in the life sciences that utilizes notions of collectivity, sociality, rich interactions, and emergent phenomena as essential explanatory tools to handle numerous persistent scientific questions in the life sciences. The contributors consider case studies of collectivity that range from microorganisms to human consensus, discussing theoretical and empirical challenges and the innovative methods and solutions scientists have devised. The contributors offer historical, philosophical, and biological perspectives on collectivity, and describe collective phenomena seen in insects, the immune system, communication, and human collectivity, with examples ranging from cooperative transport in the longhorn crazy ant to the evolution of autobiographical memory. They examine ways of explaining collectivity, including case studies and modeling approaches, and explore collectivity's explanatory power. They present a comprehensive look at a specific case of collectivity: the Holobiont notion (the idea of a multi-species collective, a host and diverse microorganisms) and the hologenome theory (which posits that the holobiont and its hologenome are a unit of adaption). The volume concludes with reflections on the work of the late physicist Eshel Ben-Jacob, pioneer in the study of collective phenomena in living systems. Contributors Oren Bader, John Beatty, Dinah R. Davison, Daniel Dor, Ofer Feinerman, Raghavendra Gadagkar, Scott F. Gilbert, Snait B. Gissis, Deborah M. Gordon, James Griesemer, Zachariah I. Grochau-Wright, Erik R. Hanschen, Eva Jablonka, Mohit Kumar Jolly, Anat Kolumbus, Ehud Lamm, Herbert Levine, Arnon Levy, Xue-Fei Li, Elisabeth A. Lloyd, Yael Lubin, Eva Maria Luef, Ehud Meron, Richard E. Michod, Samir Okasha, Simone Pika, Joan Roughgarden, Eugene Rosenberg, Ayelet Shavit, Yael Silver, Alfred I. Tauber, Ilana Zilber-Rosenberg
Download or read book Nobel Prizes and Life Sciences written by Erling Norrby and published by World Scientific. This book was released on 2010 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Nobel Prizes m natural sciences have achieved the reputation of being the ultimate accolade for scientific achievements. This honk gives a unique insight into the selection of Nobel Prize recipients, in particular the life sciences. The evolving mechanisms of selection of prize recipients are illustrated by reference to archives, which have remained secret for 1) years. Many of the prizes subjected to particular evaluation concern awards given for discoveries in the field of infectious diseases and the interconnected field of genetics. The book illustrates the individuals and environments that are conducive to scientific creativity. Nowhere is this enigmatic activity'-- the mime mover in advancing the human condition highlighted as lucidly as by identification individuals worthy of Nobel Prizes. --Book Jacket.
Download or read book Innovative Research in Life Sciences written by E. Andrew Balas and published by John Wiley & Sons. This book was released on 2018-11-08 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: “I thoroughly enjoyed reading this book as it has taken me on a journey through time, across the globe and through multiple disciplines. Indeed, we need to be thinking about these concepts and applying them every day to do our jobs better.” Farah Magrabi, Macquarie University, Australia “The reader will find intriguing not only the title but also the content of the book. I’m also pleased that public health, and even more specifically epidemiology has an important place in this ambitious discussion.” Elena Andresen, Oregon Health & Science University, USA “This book is very well written and addresses an important topic. It presents many reasons why basic scientists/researchers should establish collaborations and access information outside traditional means and not limit thinking but rather expand such and perhaps develop more innovative and translational research ventures that will advance science and not move it laterally.” Gerald Pepe, Eastern Virginia Medical School, USA “This book gathers logically and presents interestingly (with many examples) the qualities and attitudes a researcher must possess in order to become successful. On the long run, the deep and carefully reexamined research will be the one that lasts.” Zoltán Néda, Babeş-Bolyai University, Romania “I really liked the five pillars delineating the components of humanism in research. This book has made a major contribution to the research ethics literature.” David Fleming, University of Missouri, USA A comprehensive review of the research phase of life sciences from design to discovery with suggestions to improve innovation This vital resource explores the creative processes leading to biomedical innovation, identifies the obstacles and best practices of innovative laboratories, and supports the production of effective science. Innovative Research in Life Sciences draws on lessons from 400 award-winning scientists and research from leading universities. The book explores the innovative process in life sciences and puts the focus on how great ideas are born and become landmark scientific discoveries. The text provides a unique resource for developing professional competencies and applied skills of life sciences researchers. The book examines what happens before the scientific paper is submitted for publication or the innovation becomes legally protected. This phase is the most neglected but most exciting in the process of scientific creativity and innovation. The author identifies twelve competencies of innovative biomedical researchers that described and analyzed. This important resource: Highlights the research phase from design to discovery that precedes innovation disclosure Offers a step by step explanation of how to improve innovation Offers solutions for improving research and innovation productivity in the life sciences Contains a variety of statistical databases and a vast number of stories about individual discoveries Includes a process of published studies and national statistics of biomedical research and reviews the performance of research labs and academic institutions Written for academics and researchers in biomedicine, pharmaceutical science, life sciences, drug discovery, pharmacology, Innovative Research in Life Sciences offers a guide to the creative processes leading to biomedical innovation and identifies the best practices of innovative scientists and laboratories.
Download or read book Leadership in the Life Sciences written by Brian D. Smith and published by Routledge. This book was released on 2019-06-26 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: The healthcare professionals who save and extend our lives are helpless without the medicines and technologies that have revolutionised medical care. But the industry that invents, makes and provides these indispensable tools is transforming under the pressure of ageing populations, globalisation and revolutions in biological and information technology. How this industry adapts and evolves is vitally important to every one of us. This book looks inside the heads and hearts of the people who lead the global pharmaceutical and medical technology industry. It describes how they make sense of their markets and the wider life sciences economy. It reveals what they have learned about how to lead large, complex organisations to compete in dynamic, global markets. Leadership in the Life Sciences is essential reading for anyone working in or with the pharmaceutical and medical technology industry and its halo of supporting companies. Written as ten succinct lessons, it gives the reader unique insight into what the industry’s leaders are thinking. Covering topics from leadership to organisational culture, from change management to digital disruption and from competitive strategy to value-creation, each chapter distils the accumulated wisdom of those who lead the complex and turbulent life sciences industry.
