Download or read book Life Death and Nitric Oxide written by Anthony R Butler and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designated 'Molecule of the Year' in 1992 in recognition of its many biological roles, nitric oxide has wide significance in the world around us and the story of nitric oxide is still unfolding. This small and seemingly innocent molecule has for many years been known to play a significant role in both the creation of photochemical smogs and in the nitrogen cycle. It has an interesting chemistry as a metal ligand, and the bonding within the nitric oxide molecule has been extensively studied. More recently, the molecule has been in the spotlight for the role it plays in controlling blood flow, in the immune system and in brain activity. Life, Death and Nitric Oxide covers many of the topics relating to nitric oxide, from smog and catalytic converters to tumour growth, blood flow and Viagra, with the aim of finding out why such a simple molecule can do so much.
Download or read book Nitric Oxide written by Louis J. Ignarro and published by Academic Press. This book was released on 2000-09-13 with total page 1023 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nitric oxide (NO) is a gas that transmits signals in an organism. Signal transmission by a gas that is produced by one cell and which penetrates through membranes and regulates the function of another cell represents an entirely new principle for signaling in biological systems. NO is a signal molecule of key importance for the cardiovascular system acting as a regulator of blood pressure and as a gatekeeper of blood flow to different organs. NO also exerts a series of other functions, such as acting a signal molecule in the nervous system and as a weapon against infections. NO is present in most living creatures and made by many different types of cells. NO research has led to new treatments for treating heart as well as lung diseases, shock, and impotence. Scientists are currently testing whether NO can be used to stop the growth of cancerous tumors, since the gas can induce programmed cell death, apoptosis. This book is the first comprehensive text on nitric oxide to cover all aspects--basic biology, chemistry, pathobiology, effects on various disease states, and therapeutic implications. - Edited by Nobel Laureate Louis J. Ignarro, editor of the Academic Press journal, Nitric Oxide - Authored by world experts on nitric oxide - Includes an overview of basic principles of biology and chemical biology - Covers principles of pathobiology, including the nervous system, cardiovascular function, pulmonary function, and immune defense
Download or read book Mitochondria and Cell Death written by Guy C. Brown and published by . This book was released on 1999 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Mechanisms of Cell Death written by Zahra Zakeri and published by . This book was released on 1999 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contains papers from a July 1998 conference held at the Queens College Campus of the City University of New York. Papers are arranged in sections on mechanisms and general considerations, programmed (developmental) cell death, and cell death and pathological and clinical situations. Specific topics
Download or read book WHO Guidelines for Indoor Air Quality written by and published by World Health Organization. This book was released on 2010 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents WHO guidelines for the protection of public health from risks due to a number of chemicals commonly present in indoor air. The substances considered in this review, i.e. benzene, carbon monoxide, formaldehyde, naphthalene, nitrogen dioxide, polycyclic aromatic hydrocarbons (especially benzo[a]pyrene), radon, trichloroethylene and tetrachloroethylene, have indoor sources, are known in respect of their hazardousness to health and are often found indoors in concentrations of health concern. The guidelines are targeted at public health professionals involved in preventing health risks of environmental exposures, as well as specialists and authorities involved in the design and use of buildings, indoor materials and products. They provide a scientific basis for legally enforceable standards.
Download or read book Nitric Oxide in Health and Disease written by Jill Lincoln and published by Cambridge University Press. This book was released on 1997-08-28 with total page 60 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nitric oxide has a tantalizing role in health and disease: while many of its wide-ranging effects are well known, there remains much more to explore and to learn about the interactions of this fascinating molecule in physiological and pathophysiological processes. The volume reviews the myriad effects of nitric oxide as a chemical messenger in the central nervous system, peripheral nervous system, immune system and cardiovascular system. Furthermore, it provides a very practical introduction to the procedures and experimental protocols necessary to work with and study nitric oxide and its synthesizing enzyme, nitric oxide synthase, in the laboratory. In this respect the volume is unique, providing as it does a complete single-volume review of the role of nitric oxide in health and disease, and a very practical introduction to the methods and protocols involved in this intriguing and active area of biomedical research.
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Magnesium in the Central Nervous System written by Robert Vink and published by University of Adelaide Press. This book was released on 2011 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.
Download or read book Nitrogen oxides NOx why and how they are controlled written by and published by DIANE Publishing. This book was released on 1999 with total page 57 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Nitric Oxide in Plants Metabolism and Role in Stress Physiology written by M. Nasir Khan and published by Springer. This book was released on 2014-05-27 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the key features of nitric oxide (NO) in plants. Comprising nine chapters, Part I highlights its metabolism and identification in plants. Part II, which consists of eight chapters, focuses on the chemical, physical and biochemical properties of the NO molecule and its derivatives; on its functional role and mode of action; and on its signaling and interaction with phytohormones, mineral nutrients, biomolecules, ions and ion channels in plants under abiotic stresses. Combining the expertise of leading researchers in the field, the book provides a concise overview of plant NO biology and offers a valuable reference work.
Download or read book The Endothelium written by Michel Félétou and published by Morgan & Claypool Publishers. This book was released on 2011 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: The endothelium, a monolayer of endothelial cells, constitutes the inner cellular lining of the blood vessels (arteries, veins and capillaries) and the lymphatic system, and therefore is in direct contact with the blood/lymph and the circulating cells. The endothelium is a major player in the control of blood fluidity, platelet aggregation and vascular tone, a major actor in the regulation of immunology, inflammation and angiogenesis, and an important metabolizing and an endocrine organ. Endothelial cells controls vascular tone, and thereby blood flow, by synthesizing and releasing relaxing and contracting factors such as nitric oxide, metabolites of arachidonic acid via the cyclooxygenases, lipoxygenases and cytochrome P450 pathways, various peptides (endothelin, urotensin, CNP, adrenomedullin, etc.), adenosine, purines, reactive oxygen species and so on. Additionally, endothelial ectoenzymes are required steps in the generation of vasoactive hormones such as angiotensin II. An endothelial dysfunction linked to an imbalance in the synthesis and/or the release of these various endothelial factors may explain the initiation of cardiovascular pathologies (from hypertension to atherosclerosis) or their development and perpetuation. Table of Contents: Introduction / Multiple Functions of the Endothelial Cells / Calcium Signaling in Vascular Cells and Cell-to-Cell Communications / Endothelium-Dependent Regulation of Vascular Tone / Conclusion / References
Download or read book WHO global air quality guidelines written by Weltgesundheitsorganisation and published by World Health Organization. This book was released on 2021-09-07 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: The main objective of these updated global guidelines is to offer health-based air quality guideline levels, expressed as long-term or short-term concentrations for six key air pollutants: PM2.5, PM10, ozone, nitrogen dioxide, sulfur dioxide and carbon monoxide. In addition, the guidelines provide interim targets to guide reduction efforts of these pollutants, as well as good practice statements for the management of certain types of PM (i.e., black carbon/elemental carbon, ultrafine particles, particles originating from sand and duststorms). These guidelines are not legally binding standards; however, they provide WHO Member States with an evidence-informed tool, which they can use to inform legislation and policy. Ultimately, the goal of these guidelines is to help reduce levels of air pollutants in order to decrease the enormous health burden resulting from the exposure to air pollution worldwide.
Download or read book The Rate of Living written by Raymond Pearl and published by . This book was released on 1928 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Emergency Response Guidebook written by U.S. Department of Transportation and published by Simon and Schuster. This book was released on 2013-06-03 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Does the identification number 60 indicate a toxic substance or a flammable solid, in the molten state at an elevated temperature? Does the identification number 1035 indicate ethane or butane? What is the difference between natural gas transmission pipelines and natural gas distribution pipelines? If you came upon an overturned truck on the highway that was leaking, would you be able to identify if it was hazardous and know what steps to take? Questions like these and more are answered in the Emergency Response Guidebook. Learn how to identify symbols for and vehicles carrying toxic, flammable, explosive, radioactive, or otherwise harmful substances and how to respond once an incident involving those substances has been identified. Always be prepared in situations that are unfamiliar and dangerous and know how to rectify them. Keeping this guide around at all times will ensure that, if you were to come upon a transportation situation involving hazardous substances or dangerous goods, you will be able to help keep others and yourself out of danger. With color-coded pages for quick and easy reference, this is the official manual used by first responders in the United States and Canada for transportation incidents involving dangerous goods or hazardous materials.
Download or read book Nitric Oxide Sensing written by Sagarika Bhattacharya and published by CRC Press. This book was released on 2021-09-16 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although nitric oxide (NO) is an important biological signaling molecule, its free-radical electronic configuration makes it a most reactive molecule and the scariest colorless gas causing immense environmental and health hazards. Detection of NO levels in biological samples and in the atmosphere is therefore crucial. In the past few years, extensive efforts have been devoted to developing many active sensors and effective devices for detecting and quantifying atmospheric NO, NO generated in biological samples, and NO exhaled in the human breath. This book provides a concrete summary of recent state-of-the-art small-molecule probes and novel carbon nanomaterials used for chemical, photoluminescent, and electrochemical NO detection. One chapter is especially dedicated to the available devices used for detecting NO in the human breath that indirectly infers to lung inflammation. The authors with expertise in diverse dimensions have attempted to cover almost all areas of NO sensing.
Download or read book The Cerebral Circulation written by Marilyn J. Cipolla and published by Biota Publishing. This book was released on 2016-07-28 with total page 82 pages. Available in PDF, EPUB and Kindle. Book excerpt: This e-book will review special features of the cerebral circulation and how they contribute to the physiology of the brain. It describes structural and functional properties of the cerebral circulation that are unique to the brain, an organ with high metabolic demands and the need for tight water and ion homeostasis. Autoregulation is pronounced in the brain, with myogenic, metabolic and neurogenic mechanisms contributing to maintain relatively constant blood flow during both increases and decreases in pressure. In addition, unlike peripheral organs where the majority of vascular resistance resides in small arteries and arterioles, large extracranial and intracranial arteries contribute significantly to vascular resistance in the brain. The prominent role of large arteries in cerebrovascular resistance helps maintain blood flow and protect downstream vessels during changes in perfusion pressure. The cerebral endothelium is also unique in that its barrier properties are in some way more like epithelium than endothelium in the periphery. The cerebral endothelium, known as the blood-brain barrier, has specialized tight junctions that do not allow ions to pass freely and has very low hydraulic conductivity and transcellular transport. This special configuration modifies Starling's forces in the brain microcirculation such that ions retained in the vascular lumen oppose water movement due to hydrostatic pressure. Tight water regulation is necessary in the brain because it has limited capacity for expansion within the skull. Increased intracranial pressure due to vasogenic edema can cause severe neurologic complications and death.
Download or read book Surgical Treatment written by René Holzheimer and published by . This book was released on 2001 with total page 880 pages. Available in PDF, EPUB and Kindle. Book excerpt:
