Download or read book Lewis Basicity and Affinity Scales written by Christian Laurence and published by John Wiley & Sons. This book was released on 2009-12-23 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Lewis concept of acids and bases is discussed in every general, organic and inorganic chemistry textbook. This is usually just a descriptive treatment, as it is not possible to devise a single numerical scale suitable for all occasions. However quantitative Lewis acid-base chemistry can be developed by compiling reaction-specific basicity scales which can be used in specific branches of chemistry and biochemistry. Lewis Basicity and Affinity Scales: Data and Measurementbrings together for the first time a comprehensive range of Lewis basicity/affinity data in one volume. More than 2400 equilibrium constants of acid-base reactions, 1500 complexation enthalpies, and nearly 2000 infrared and ultraviolet shifts upon complexation are gathered together in 25 thermodynamic and spectroscopic scales of basicity and/or affinity. For each scale, the definition, the method of measurement, an exhaustive database, and a critical discussion are given. All the data have been critically examined; some have been re-measured; literature gaps have been filled by original measurements; and each scale has been made homogeneous. This collection of data will enable experimental chemists to better understand and predict the numerous chemical, physical and biological properties that depend upon Lewis basicity. Chemometricians will be able to apply their methods to the data matrices constructed from this book in order to identify the factors which influence basicity and basicity-dependent properties. In addition, measured experimental basicities and affinities are essential to computational chemists for the validation, calibration and establishment of reliable computational methods for quantifying and explaining intermolecular forces and the chemical bond. Lewis Basicity and Affinity Scales: Data and Measurement is an essential single-source desktop reference for research scientists, engineers, and students in academia, research institutes and industry, in all areas of chemistry from fundamental to applied research. "The book is a noteworthy piece of work and represents a timely and vast accumulation of knowledge regarding Lewis bases that brings together accurate thermodynamic and spectroscopic data on typical reference Lewis acids. As such, it should serve as a useful and general guide to basicity." J. AM. CHEM. SOC. 2011, 133, 642
Download or read book Lewis Acids and Selectivity in Organic Synthesis written by M. Santelli and published by CRC Press. This book was released on 1995-11-21 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lewis acids provide inexpensive access to elaborated molecules obtained with high selectivities (regio-, stereo-, and enantioselectivity). Lewis Acids and Selectivity in Organic Synthesis is the first book to deal with these new and promising roles of Lewis acids. The book begins with general considerations on Lewis acids and a description of Lewis acid-carbonyl complexes, which are involved in most of the reactions described: ene reactions, allylsilane and allyltin addition to carbonyl compounds, addition of nucleophiles to acetals, conjugated addition of allylsilanes and allyltins to unsaturated carbonyl compounds (Sakurai reaction), and Diels-Alder reaction. Subsequent chapters examine these issue in detail, with special attention given to the way Lewis acids induce diastereo- and enantioselectivity. The extensive use of schemes (approximately 1000) ensures rapid visual uptake of the information. Lewis Acids and Selectivity in Organic Synthesis serves as a valuable source of information for all who face the challenge of selectivity in organic synthesis.
Download or read book The Lewis Acid base Concepts written by William B. Jensen and published by John Wiley & Sons. This book was released on 1980 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Chiral Lewis Acids in Organic Synthesis written by Jacek Mlynarski and published by John Wiley & Sons. This book was released on 2017-10-23 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: A complete overview covering the application of metal-based chiral Lewis acids from all parts of the periodic table, the Author emphasizes the most recent contributions to the field as well as prominent direction of development. The book discusses the design of chiral complexes as well as a wide spectrum of reactions promoted by various chiral Lewis acids, including water-compatible acids as well as the most important applications in the chemical and pharmaceutical industries. A must-have for catalytic and organic chemists working in the field, both in academia and industry, as well as pharmaceutical and medicinal chemists.
Download or read book Selectivities in Lewis Acid Promoted Reactions written by Dieter Schinzer and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ASI workshop on "Selectivities in Lewis Acid Promoted Reactions" held in the Emmantina-Hotel in Athens-Glyfada, Greece, October 2-7, 1988 was held to bring some light into the darkness of Lewis acid induced processes. As such the workshop reflects some current trends in organic synthesis, where Lewis acids are becoming a powerful tool in many different modern reactions, e.g. Diels-Alder reactions, Ene reactions, Sakurai reactions, and in general silicon and tin chemistry. The objective of this meeting was to bring together most of the world experts in the field to discuss the major reactions promoted by Lewis acids. Organic synthesis will play a major role in this book connected with some fundamental mechanistic work on allylsilane and -tin chemistry. Both natural product synthesis and unnatural molecules are presented in the chapters. The book presents all the 15 invited lectures and the contributions of 15 posters. I am confident that the material presented in this book will stimulate the chemistry, which has been discussed on our meeting, around the world. The meeting and the book were only possible through a grant of the NATO Scientific Affairs Devision and financial support by the following companies: Kali Chemie (Hannover, W-Germany), E. Merck (Darmstadt, W-Germany), Sandoz (Basel, Switzerland), Schering (Berlin, W-Germany).
Download or read book The Essential Guide to Lewis Acids written by Oliver M. Sandes and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lewis acids have been utilized to activate molecules, whether it be the generation of a simple Lewis acid-base adduct or the coordination and activation of a substrate molecule in a catalytic transformation. When designing new Lewis acids, a synthetic chemist has to consider the properties of the Lewis acid. As such, this compilation describes the methods used in measuring Lewis acid strength, including a ladder diagram comparing the Lewis acid strength of both main group and metal-based Lewis acids. Since carboxylic acid derivatives are commercially available, non-toxic, cheap and normally stable to air and moisture, carboxylic acid derivatives are ideal reactants for synthetic strategy. The decarboxylative coupling reaction is discussed as one of the most important tools for organic synthesis, and remarkable progress has been made in this field. In conclusion, the authors highlight recent advances achieved in the development of processes for esters production from glycerol and terpenic alcohols in metal salts-catalyzed reactions, using acetic acid as the carbonylic reactant. The effects of main reaction parameters such as concentration, temperature and reactants stoichiometry are assessed. A comparison with traditional acid catalysts used in these reactions is also performed.
Download or read book Cooperative Catalysis written by René Peters and published by John Wiley & Sons. This book was released on 2015-04-27 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by experts in the field, this is a much-needed overview of the rapidly emerging field of cooperative catalysis. The authors focus on the design and development of novel high-performance catalysts for applications in organic synthesis (particularly asymmetric synthesis), covering a broad range of topics, from the latest progress in Lewis acid / Br?nsted base catalysis to e.g. metal-assisted organo catalysis, cooperative metal/enzyme catalysis, and cooperative catalysis in polymerization reactions and on solid surfaces. The chapters are classified according to the type of cooperating activating groups, and describe in detail the different strategies of cooperative activation, highlighting their respective advantages and pitfalls. As a result, readers will learn about the different concepts of cooperative catalysis, their corresponding modes of operation and their applications, thus helping to find a solution to a specific synthetic catalysis problem.
Download or read book Lewis Acid base Reaction Chemistry written by Mark R. Leach and published by . This book was released on 1999 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Complexes and First row Transition Elements written by David Nicholls and published by . This book was released on 1974 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Aldol Reactions written by Rainer Mahrwald and published by Springer Science & Business Media. This book was released on 2009-05-15 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aldol Reactions provides a comprehensive up-to-date overview of aldol reactions including application of different metal enolates; catalytic aldol additions catalyzed by different Lewis acids and Lewis bases; enantioselective direct aldol additions; antibodies and enzyme catalyzed aldol additions and the recent aggressive development of organocatalyzed aldol additions. The power of each method is demonstrated by several applications in total synthesis of natural products. The pros and cons of these methodologies with regard to stereoselectivity, regioselectivity and application in total synthesis of natural products are discussed. Great importance is set to the diverse possibilities of the manual of aldol reaction to install required configurations in complicated natural product synthesis.
Download or read book Chemistry written by Bruce Averill and published by . This book was released on 2007 with total page 1233 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emphasises on contemporary applications and an intuitive problem-solving approach that helps students discover the exciting potential of chemical science. This book incorporates fresh applications from the three major areas of modern research: materials, environmental chemistry, and biological science.
Download or read book Procedures in Cosmetic Dermatology Series Chemical Peels EBook written by Suzan Obagi and published by Elsevier Health Sciences. This book was released on 2020-03-01 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part of the practical and dynamic Procedures in Cosmetic Dermatology Series, Chemical Peels, 3rd Edition, brings you up to speed with today's best uses of traditional and new acids for skin rejuvenation. This well-organized, superbly illustrated text covers every aspect of this must-know field, including patient evaluation, skin preparation, procedural technique from light peels to advanced deep peels, and managing complications. Dr. Suzan Obagi leads a team of global experts to offer evidence-based, procedural how-to's and step-by-step advice on proper techniques, pitfalls, and tricks of the trade, so you can successfully incorporate the latest procedures into your practice. - Features many new chapters dedicated to specific peels or skin conditions: trichloroacetic acid (TCA) peels of the chest, neck, and upper extremities; peels as an adjuvant treatment of acne; chemical peels in male patients; several chapters on unique approaches to acne scars; a chapter on combining peels with surgical procedures; and several chapters on safely performing deeper, modified phenol peels. - Covers new acid formulas, new peel types, and need-to-know procedures such as the combined Jessner-TCA-retinoid peel and how to vary technique for darker skin types. - Features a well-organized format with key points lists, pearls, and case studies as they appear in practice. - Includes many new images and procedural videos that depict exactly how to perform the techniques, allowing you to easily incorporate chemical peels into your practice and take your knowledge of chemical peels to the next level.
Download or read book Chemistry written by Andrew Burrows and published by Oxford University Press, USA. This book was released on 2013-03-21 with total page 1431 pages. Available in PDF, EPUB and Kindle. Book excerpt: New to this Edition:
Download or read book Organic Chemistry written by Michael B. Smith and published by CRC Press. This book was released on 2011-06-29 with total page 1594 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on the premise that many, if not most, reactions in organic chemistry can be explained by variations of fundamental acid-base concepts, Organic Chemistry: An Acid–Base Approach provides a framework for understanding the subject that goes beyond mere memorization. The individual steps in many important mechanisms rely on acid–base reactions, and the ability to see these relationships makes understanding organic chemistry easier. Using several techniques to develop a relational understanding, this textbook helps students fully grasp the essential concepts at the root of organic chemistry. Providing a practical learning experience with numerous opportunities for self-testing, the book contains: Checklists of what students need to know before they begin to study a topic Checklists of concepts to be fully understood before moving to the next subject area Homework problems directly tied to each concept at the end of each chapter Embedded problems with answers throughout the material Experimental details and mechanisms for key reactions The reactions and mechanisms contained in the book describe the most fundamental concepts that are used in industry, biological chemistry and biochemistry, molecular biology, and pharmacy. The concepts presented constitute the fundamental basis of life processes, making them critical to the study of medicine. Reflecting this emphasis, most chapters end with a brief section that describes biological applications for each concept. This text provides students with the skills to proceed to the next level of study, offering a fundamental understanding of acids and bases applied to organic transformations and organic molecules.
Download or read book The Practice of Chemistry Study Guide Solutions Manual written by Pamela Mills and published by Macmillan. This book was released on 2003-04-14 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designed to help students understand the material better and avoid common mistakes. Also includes solutions and explanations to odd-numbered exercises.
Download or read book Selective Glycosylations written by Clay S. Bennett and published by John Wiley & Sons. This book was released on 2017-01-25 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive summary of novel approaches to the stereoselective construction of glycosidic linkages, covering modern glycosylation methods and their use and application in natural product synthesis and drug discovery. Clearly divided into five sections, the first describes recent advances in classical methodologies in carbohydrate chemistry, while the second goes on to deal with newer chemistries developed to control selectivity in glycosylation reactions. Section three is devoted to selective glycosylation reactions that rely on the use of catalytic promoters. Section four describes modern approaches for controlling regioselectivity in carbohydrate synthesis. The final section focuses on new developments in the construction of "unusual" sugars and is rounded off by a presentation of modern procedures for the construction of glycosylated natural products. By providing the latest advances in glycosylation as well as information on mechanistic aspects of the reaction, this is an invaluable reference for both specialists and beginners in this booming interdisciplinary field that includes carbohydrate chemistry, organic synthesis, catalysis, and biochemistry.
Download or read book Anion Binding Catalysis written by Olga Garcia-Mancheno and published by John Wiley & Sons. This book was released on 2022-03-21 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explores the potential of new types of anion-binding catalysts to solve challenging synthetic problems Anion-Binding Catalysis introduces readers to the use of anion-binding processes in catalytic chemical activation, exploring how this approach can contribute to the future design of novel synthetic transformations. Featuring contributions by world-renowned scientists in the field, this authoritative volume describes the structure, properties, and catalytic applications of anions as well as synthetic applications and practical analytical methods. In-depth chapters are organized by type of catalyst rather than reaction type, providing readers with an accessible overview of the existing classes of effective catalysts. The authors discuss the use of halogens as counteranions, the combination of (thio)urea and squaramide-based anion-binding with other types of organocatalysis, anion-binding catalysis by pnictogen and tetrel bonding, nucleophilic co-catalysis, anion-binding catalysis by pnictogen and tetrel bonding, and more. Helping readers appreciate and evaluate the potential of anion-binding catalysis, this timely book: Illustrates the historical development, activation mode, and importance of anion-binding in chemical catalysis Explains the analytic methods used to determine the anion-binding affinity of the catalysts Describes catalytic and synthetic applications of common NH- and OH-based hydrogen-donor catalysts as well as C-H triazole/triazolium catalysts Covers amino-catalysis involving enamine, dienamine, or iminium activation approaches Discusses new trends in the field of anion-binding catalysis, such as the combination of anion-binding with other types of catalysis Presenting the current state of the field as well as the synthetic potential of anion-binding catalysis in future, Anion-Binding Catalysis is essential reading for researchers in both academia and industry involved in organic synthesis, homogeneous catalysis, and pharmaceutical chemistry.
