Download or read book Les nouveaux anticoagulants oraux indications actuelles et perspectives d avenir written by Thomas Gerbaux and published by . This book was released on 2013 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Les nouveaux anticoagulants oraux sont apparus depuis quelques années sur le marché français. Ces molécules, représentées en premier lieu par le dabigatran, le rivaroxaban et l'apixaban, ont d'abord été cantonnées à la seule indication de prévention des événements thromboemboliques veineux après prothèse totale de hanche ou de genou. Les laboratoires ont par la suite fait des demandes d'extension d'indication, avec des fortunes diverses. Certaines sont en cours d'examen par les agences du médicament, et, parallèlement, de nouvelles molécules sont en cours de développement. L'anticoagulation est un paramètre physiologique intervenant dans de nombreuses pathologies, et la population-cible augmente. Sa maîtrise et sa justesse sont essentielles : trop faible et le traitement sera inefficace, trop forte et le patient sera sujet à des hémorragies ; les conséquences pour le patient pouvant être graves dans les deux cas de figure. A l'heure des entretiens pharmaceutiques, le pharmacien d'officine a un rôle d'accompagnement auprès des patients afin de s'assurer d'une bonne observance et d'une efficacité optimale du traitement.

Download or read book Etat des lieux de l anticoagulation des sujets de plus de 75 ans en fibrillation atriale permanente non valvulaire en Bretagne written by Claire Portal and published by . This book was released on 2013 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contexte : La fibrillation atriale du sujet de plus de 75 ans est une pathologie fréquente nécessitant une anticoagulation efficace. Jusqu’à peu, les anticoagulants oraux n’étaient représentés que par les AVK que de nombreux médecins hésitaient encore à prescrire chez les sujets âgés, leur préférant souvent un antiagrégant plaquettaire. Depuis fin 2011, deux nouveaux anticoagulants oraux, Pradaxa et Xarelto ont obtenu l’AMM dans le traitement de la fibrillation atriale, source d’une possible évolution des pratiques médicales. Objectifs : Dresser un bilan des pratiques actuelles des généralistes bretons concernant l'anticoagulation des sujets de plus de 75 ans en fibrillation atriale non valvulaire. Envisager les perspectives d’évolution thérapeutique pour les patients déjà sous AVK ou Kardégic, suite à l’arrivée des nouveaux anticoagulants oraux (NACO). Méthode : Etude quantitative de 317 questionnaires auto administrés par un échantillon cible de généralistes bretons Résultats : 72,3% des généralistes bretons avaient encore des patients de plus de 75 ans en fibrillation atriale traités uniquement par Kardégic, mais seuls 50,9% d’entre eux envisageaient de le remplacer par un NACO. Le Previscan restait l’AVK utilisé préférentiellement par 79,7% des généralistes bretons au détriment de la Coumadine. Chez les patients bien équilibrés sous AVK, 31,1% des médecins jugeaient utile un relais AVK/NACO, mais seuls 13,8% envisageaient de remplacer systématiquement les AVK par les NACO. Chez les sujets mal équilibrés sous AVK, 89,4% envisageaient de remplacer les AVK par les NACO. Conclusion : Trop de patients de plus de 75 ans en fibrillation atriale n’étaient toujours pas anticoagulés et le Previscan restait trop prescrit au détriment de la Coumadine. Le remplacement du Kardégic par les NACO divisait l’opinion et la grande majorité n’était pas en faveur d’un relais systématique AVK/NACO chez les sujets bien équilibrés sous AVK. En revanche, un relais AVK/NACO chez les sujets mal équilibrés sous AVK faisait consensus.

Download or read book Utilisation des nouveaux anticoagulants oraux written by Caroline Vigne and published by . This book was released on 2014 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Les anticoagulants, antivitamines K et héparines sont sur le marché depuis plusieurs dizaines d’années et sont devenus des références dans le traitement préventif et curatif des maladies thromboemboliques. Néanmoins, leurs effets secondaires et leurs inconvénients d’utilisation ont poussé l’industrie pharmaceutique à rechercher un anticoagulant idéal. Trois molécules, utilisables par voie orale, ont donc fait récemment leur apparition sur le marché : 2 inhibiteurs du facteur Xa (le rivaroxaban et l’apixaban) et un inhibiteur de la thrombine (le dabigatran), le facteur Xa et la thrombine étant des cibles idéales pour un traitement anticoagulant. Cependant, plusieurs questions se sont rapidement posées, notamment concernant le risque hémorragique, puisque ce sont des molécules qui ne possèdent pas d’antidote et pour lesquels les tests biologiques usuels ne sont pas utilisables. Dans ce travail, nous avons évalué leurs conditions de prescription au travers d’une étude de 12 cas de patients hospitalisés et traités par ces nouveaux anticoagulants oraux. Cette étude a permis de rendre compte du profil des patients traités par ces nouvelles molécules et d’évaluer si les recommandations et les nombreux rappels de l’ANSM ont été suivis par les prescripteurs. Ce travail démontre clairement la nécessité d’encadrer l’utilisation de ces molécules et de suivre les recommandations, notamment concernant leurs indications, leurs posologies et adaptations posologiques, leurs contre-indications et précautions d’emploi.

Download or read book Critical Care Nursing written by Linda Diann Urden and published by Saunders. This book was released on 2010 with total page 1242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on critical care nursing, this full-color text provides an examination of the important aspects of critical care nursing. It is organized in ten units around alterations in body systems.

Download or read book Global Burden of Disease and Risk Factors written by Alan D. Lopez and published by World Bank Publications. This book was released on 2006-04-02 with total page 511 pages. Available in PDF, EPUB and Kindle. Book excerpt: Strategic health planning, the cornerstone of initiatives designed to achieve health improvement goals around the world, requires an understanding of the comparative burden of diseases and injuries, their corresponding risk factors and the likely effects of invervention options. The Global Burden of Disease framework, originally published in 1990, has been widely adopted as the preferred method for health accounting and has become the standard to guide the setting of health research priorities. This publication sets out an updated assessment of the situation, with an analysis of trends observed since 1990 and a chapter on the sensitivity of GBD estimates to various sources of uncertainty in methods and data.

Download or read book Gharial Conservation in Nepal written by Tirtha Man Maskey and published by . This book was released on 2008 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book A Call to Heal written by Ian Renwick McWhinney and published by . This book was released on 2013-02 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Fish Stocks and Fisheries of Lake Victoria written by Frans Witte and published by . This book was released on 1996 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The results of eighteen years research on the fisheries of Lake Victoria are presented here in a single volume. The introduction is followed by sections dealing successively with fish and fisheries, methodologies for sampling, gear and boats, methods for monitoring fish stocks, management and processing of data, fishery statistics and methods for monitoring the fishery. It, therefore, proceeds logically from fish to fisherman, passing through the scientific administrative steps needed to acquire and interpret the data necessary to ensure good management. The main body of the text is complemented by appendices which provide specific biological information on the major fish species of Lake Victoria, including a detailed key."--BOOK JACKET.

Download or read book Sheep and Goat Production written by I. E. Coop and published by Elsevier Science & Technology. This book was released on 1982 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ecology and distribution; Breeding; Reproduction; Maintenance and growth; Pregnancy; Lactation of suckling ewes and does; Nutritional diseases; Infectious diseases of sheep and goats; Internal parasites of sheep and goats; External parasites of sheep and goats; Growth and characteristics of wool and hair; Wiik grading and marketing; Livestock and meat marketing and grading; Carcase and meat qualities; Milk production in sheep and goats; Systems, biological and economic efficiencies; Very extensive systems; Extensive grazing systems; Intensive grassland systems; Intensive arable systems; Very intensive systems; Government controlled systems; Migratory (Transhumance) systems; Nomadic systems; Village and smallholder systems; List of contributors.

Download or read book Office Emergencies written by Marjorie A. Bowman and published by . This book was released on 2003 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inside, you'll find practical information on how to handle the most common emergencies that present in primary care offices and urgent care centers -- whether in person or over the telephone.

Download or read book Artificial Intelligence for COVID 19 written by Diego Oliva and published by Springer Nature. This book was released on 2021-07-19 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a compilation of the most recent implementation of artificial intelligence methods for solving different problems generated by the COVID-19. The problems addressed came from different fields and not only from medicine. The information contained in the book explores different areas of machine and deep learning, advanced image processing, computational intelligence, IoT, robotics and automation, optimization, mathematical modeling, neural networks, information technology, big data, data processing, data mining, and likewise. Moreover, the chapters include the theory and methodologies used to provide an overview of applying these tools to the useful contribution to help to face the emerging disaster. The book is primarily intended for researchers, decision makers, practitioners, and readers interested in these subject matters. The book is useful also as rich case studies and project proposals for postgraduate courses in those specializations.

Download or read book Is Gwyneth Paltrow Wrong About Everything written by Timothy Caulfield and published by Beacon Press. This book was released on 2016-05-10 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: An exploration of the effect our celebrity-dominated culture has on our ideas of what it means to live "the good life" What would happen if an average Joe tried out for American Idol, underwent a professional makeover, endured Gwyneth Paltrow’s “Clean Cleanse,” and followed the outrageous rituals of the rich and famous? Health law policy researcher Timothy Caulfield finds out in this thoroughly unique, engaging, and provocative book about celebrity culture and its iron grip on today’s society. Over the past decade, our perceptions of beauty, health, success, and happiness have become increasingly framed by a popular culture steeped in celebrity influence and ever more disconnected from reality. Research tells us that our health decisions and goals are influenced by celebrity culture and endorsements, our children's ambitions are now overwhelmingly governed by the fantasy of fame, and the ideals of beauty and success are mediated through a celebrity-dominated worldview. But while much has been written about the cause of our obsession with the rich and famous, Caulfield argues that not enough has been done to debunk celebrity messages and promises about health, diet, beauty, or happiness. From super-thin models to Gwyneth Paltrow’s endorsement of a gluten free-diet for almost anyone, celebrity opinions have the power to dominate our conversations and outlooks. In this book, Caulfield provides an entertaining look into the celebrity world, including vivid accounts of his own experiences trying out for American Idol, having his skin resurfaced, and doing the cleanse; interviews with actual celebrities; thought-provoking facts, and a practical and evidence-based reality check on our own celebrity ambitions.

Download or read book Management of Low Back Pain in Primary Care written by Richard Bartley and published by Butterworth-Heinemann. This book was released on 2001 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Low back pain is one of the commonest conditions seen in general practice. This book has therefore been written to make it easier for GPs to manage low back pain by providing a simply written guide to give the GP an invaluable perspective on management.

Download or read book Canadian Family Medicine Clinical Cards written by David Keegan MD and published by SHARC-FM. This book was released on 2014-07-21 with total page 29 pages. Available in PDF, EPUB and Kindle. Book excerpt: These are peer-reviewed handy point-of-care tools to support clinical learning in Family Medicine. The content is aligned with SHARC-FM - the Shared Canadian Curriculum in Family Medicine. Objectives and more information is available at sharcfm.com.

Download or read book Crocodilian Biology and Evolution written by Gordon Clifford Grigg and published by Surrey Beatty and Sons. This book was released on 2001 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This volume grew out of a conference Crocodilian Biology and Evolution which was held at the University of Queensland in July 1998, with significant support from the (then) Department of Zoology" - Introd.

Download or read book The Challenge for Africa written by Wangari Maathai and published by Anchor. This book was released on 2009-04-07 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this groundbreaking work, the Nobel Peace Prize-winner and founder of the Green Belt Movement offers a new perspective on the troubles facing Africa today. Too often these challenges are portrayed by the media in extreme terms connoting poverty, dependence, and desperation. Wangari Maathai, the author of Unbowed, sees things differently, and here she argues for a moral revolution among Africans themselves. Illuminating the complex and dynamic nature of the continent, Maathai offers “hardheaded hope” and “realistic options” for change and improvement. She deftly describes what Africans can and need to do for themselves, stressing all the while responsibility and accountability. Impassioned and empathetic, The Challenge for Africa is a book of immense importance.

Download or read book ENT Emergencies written by John L. Dornhoffer and published by . This book was released on 2008 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The head and neck, as an anatomical cross roads of multiple functions critical to human well being, including respiration, digestion, sensation, communication, and aesthetics, presents disorders that acutely threaten these vital systems. As with any emergency situation, information devoted to the priorities of management: airway, breathing, circulation, and disability are presented for otolaryngic emergencies that may manifest at each of these levels in the form of acute airway obstruction, epistaxis, and the gamut of traumatic, infectious, and inflammatory disorders that affect special sensation, neurologic function, and cosmesis. Discussed in this issue is the use of modalities such as endoscopy, optics, and radiologic imaging as a means to earlier diagnosis, detailed anatomic assessment, and minimally invasive surgery used in the emergency setting. This text strives to keep practitioners at the forefront in the management of ENT emergencies. Experts in otolaryngology describe those conditions that require urgent evaluation and treatment but are also relatively common. Where evidence-based medicine is lacking, comprehensive reviews of the controversies are presented along with logical treatment algorithms based on clinical expertise. This issue of Otolaryngologic Clinics should be highly relevant to the otolaryngologist as well as the general practitioner and emergency physician.