Download or read book Lean Manufacturing In Pharmaceutical Industry written by Ntin Kapoor and published by Lulu.com. This book was released on 2013-11-20 with total page 37 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to the origin of Lean, it is widely used in manufacturing focussed companies like automotive industry but in current scenario the concept of Lean Manufacturing has been adopted by different businesses as well. In view of this, the objective of the report is to study the different approaches of Lean Manufacturing and the challenges which Pharma companies are facing in implementation of Lean Manufacturing and also the progress report of some companies to know whether any drug manufacture has truly made some progress or not.
Download or read book Lean manufacturing et application l industrie pharmaceutique written by Afef Meherzi and published by . This book was released on 2009 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Initialement mis au point par Toyota, le système LEAN est une méthode de management qui permet à l'entreprise d'être au plus près de la demande client et d'éliminer tous les gaspillages. Véritable révolution industrielle, la pratique du Lean permet de se concentrer sur la production de valeur ajoutée. En améliorant sans cesse le processus de travail et en tirant parti de la qualité de la main d'oeuvre, elle donne les moyens de réduire les coûts en produisant ce qui est strictement nécessaire. Longtemps, l'industrie pharmaceutique s'est considéré comme une industrie "à part" du fait du poids de la réglementation et de la spécificité de ses processus. Mais surtout, elle ne s'est pas tournée spontanément vers le lean car la production et la logistique ne représentent qu'une faible partie de la valeur du produit par rapport au poids de la molécule découverte. Depuis 5 à 10 ans, avec une recherche en panne de grandes découvertes, une réelle évolution commence à se faire sentir au sein de grands groupes pharmaceutiques qui adoptent les pratiques Lean des secteurs aéronautiques et automobiles. Ainsi, dans un contexte de contraintes de plus en plus fortes, le Lean permet aux laboratoires d'être plus souples, d'accélérer ses processus, de disposer de plus de capacités pour faire face à la demande du marché. Cette étude est composée de deux grandes parties. La première évoque les concepts du Lean et six sigmas. La seconde explique l'application concrète de la méthode SMED : outil majeur du Lean Manufacturing dans l'industrie pharmaceutique.
Download or read book Digital Technologies and Applications written by Saad Motahhir and published by Springer Nature. This book was released on with total page 577 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Une application du Lean dans l industrie pharmaceutique written by Julien Meste and published by . This book was released on 2017 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comme toutes industries dans le contexte économique actuel, les industries de santé souhaitent améliorer leur performance, leur qualité et réduire leurs coûts. Dès lors la philosophie Lean et ses outils semblent être une réponse appropriée sous certaines conditions. Cette démarche qui vise à la réduction des gaspillages doit être menée en collaboration avec tous les acteurs. La place de l'Homme et son implication est essentielle si l'on souhaite la réussite du projet et sa pérennité. La thèse vous est proposée en deux parties complémentaires. La première partie développe les concepts, les méthodes et les outils du Lean Manufacturing avec une accentuation sur les notions abordées dans les projets réalisés. La seconde partie illustre la réalisation des deux projets au sein d'un atelier de production pharmaceutique. Le premier projet a été la refonte du fond et de la forme d'un tableau de Management Visuel. Le second projet a été la mise en place d'une méthode visuelle de résolution des problèmes.
Download or read book Creating a Lean R D System written by Terence M Barnhart and published by CRC Press. This book was released on 2012-08-20 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ability to find and remove barriers between people and their systems in R&D can almost guarantee a doubling in performance, and often delivers multiples of that. R&D teams that have smooth handoffs deliver 100 percent of the required knowledge at those handoffs. As a result, such teams do not lose critical information, have unexpected knowledge gaps appear in their projects, or have uncoordinated knowledge transfers that waste minutes, days, and even months every year. Creating a Lean R&D System: Lean Principles and Approaches for Pharmaceutical and Research-Based Organizations lays out the logic of why Lean implementation isn’t strictly for manufacturing and describes why it can be just as effective in R&D organizations. Terence Barnhart, former senior director of continuous improvement at Pfizer R&D, describes the theoretical and physical underpinnings of creating a Lean transformation in any R&D organization, as exemplified by the Lean transformation initiated within the R&D division of a global pharmaceutical company. Describing how to merge Lean principles with the cultural virtues inherent in R&D, the book presents Lean approaches that can be easily applied in pharmaceutical and research-based organizations. It takes a strategic approach to solving two problems unique to the Lean field. The first is in noting the key distinctions between R&D and manufacturing, and developing a Lean approach specific to the R&D environment. The second is that it proposes a systematic middle-out (merger/maneuver) strategy to help you initiate and sustain a Lean culture within your pharmaceutical R&D organization that will help you immediately engage all stakeholders involved.
Download or read book Lean Biomanufacturing written by Nigel J Smart and published by Elsevier. This book was released on 2013-10-31 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: With decreasing profit margins, increasing cost pressures, growing regulatory compliance concerns, mounting pressure from generic drugs and increasing anxiety about the future of healthcare reimbursement, pharmaceutical manufacturers are now forced to re-examine and re-assess the way they have been doing things. In order to sustain profitability, these companies are looking to reduce waste (of all kinds), improve efficiency and increase productivity. Many of them are taking a closer look at lean manufacturing as a way to achieve these goals. Lean biomanufacturing re-visits lean principles and then applies them sympathetically - in a highly practical approach - to the specific needs of pharmaceutical processes, which present significantly different challenges to more mainstream manufacturing processes. A major goal of the book is to highlight those problems and issues that appear more specific or unique to biopharmaceutical manufacturing situations and to provide some insights into what challenges are the important ones to solve and what techniques, tools and mechanisms to employ to be successful.Following an introduction to lean biomanufacturing, the book goes on to discuss lean technologies and methods applied in biomanufacturing. Later chapters cover the creation and implementation of the Transition Plan, issues facing the biopharmaceutical industry, creating a lean approach towards biopharmaceutical processes and the contribution of simulation models in developing these processes. The final chapter covers examples of new technology innovations which help facilitate lean biomanufacturing. A focus on the issues associated with the application of lean principles to biomanufacturing Practical examples of factors which can affect biopharmaceutical processes Coverage of key factors which require integration to run an efficient biopharmaceutical process
Download or read book The Future of Pharmaceutical Product Development and Research written by and published by Academic Press. This book was released on 2020-08-19 with total page 976 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Future of Pharmaceutical Product Development and Research examines the latest developments in the pharmaceutical sciences, also highlighting key developments, research and future opportunities. Written by experts in the field, this volume in the Advances in Pharmaceutical Product Development and Research series deepens our understanding of the product development phase of drug discovery and drug development. Each chapter covers fundamental principles, advanced methodologies and technologies employed by pharmaceutical scientists, researchers and the pharmaceutical industry. The book focuses on excipients, radiopharmaceuticals, and how manufacturing should be conducted in an environment that follows Good Manufacturing Practice (GMP) guidelines. Researchers and students will find this book to be a comprehensive resource for those working in, and studying, pharmaceuticals, cosmetics, biotechnology, foods and related industries. Provides an overview of practical information for clinical trials Outlines how to ensure an environment that follows Good Manufacturing Practice (GMP) Examines recent developments and suggests future directions for drug production methods and techniques
Download or read book Best Practices in Lean Manufacturing written by José Roberto Díaz-Reza and published by Springer Nature. This book was released on 2022-03-19 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reports four structural equation models (SEM) for quantifying the relationship between the most important lean manufacturing (LM) practices applied to the manufacturing industry. The SEMs are evaluated using 220 responses to a survey applied to manufacturing companies applying LM principles in the production system and are related to: distribution and maintenance, production process and quality system, supply chain and quality, and an integrator model. The findings identify the most important activities for every LM practices and how they are related. These relationship’ values will help administrators, managers, engineers to focus their efforts on these most important activities, facilitating the decision-making process.
Download or read book Handbook of Research on Design and Management of Lean Production Systems written by Modrák, Vladimír and published by IGI Global. This book was released on 2014-01-31 with total page 487 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book explores the recent advancements in the areas of lean production, management, and the system and layout design for manufacturing environments, capturing the building blocks of lean transformation on a shop floor level"--
Download or read book Trends in Industrial Engineering Applications to Manufacturing Process written by Jorge Luis García-Alcaraz and published by Springer Nature. This book was released on 2021-07-02 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers supply chain and logistics, production and manufacturing systems as well as human factors. Topics such as applications to procurements from suppliers, suppliers developments and relationships with suppliers are reported. The techniques and tools applied to production processes, such as, machinery maintenance and quick changeover, are described in detail. The book also presents human factors as the main component in the industrial engineering field, reporting some successful teamwork organizations for improvements and applied ergonomics, among others.
Download or read book Application du lean manufacturing dans l industrie pharmaceutique written by Sofiène Arfa and published by . This book was released on 2012 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Design of Experiments for Chemical Pharmaceutical Food and Industrial Applications written by Carrillo-Cedillo, Eugenia Gabriela and published by IGI Global. This book was released on 2019-12-13 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: Statistics is a key characteristic that assists a wide variety of professions including business, government, and factual sciences. Companies need data calculation to make informed decisions that help maintain their relevance. Design of experiments (DOE) is a set of active techniques that provides a more efficient approach for industries to test their processes and form effective conclusions. Experimental design can be implemented into multiple professions, and it is a necessity to promote applicable research on this up-and-coming method. Design of Experiments for Chemical, Pharmaceutical, Food, and Industrial Applications is a pivotal reference source that seeks to increase the use of design of experiments to optimize and improve analytical methods and productive processes in order to use less resources and time. While highlighting topics such as multivariate methods, factorial experiments, and pharmaceutical research, this publication is ideally designed for industrial designers, research scientists, chemical engineers, managers, academicians, and students seeking current research on advanced and multivariate statistics.
Download or read book Flexible Automation and Intelligent Manufacturing Establishing Bridges for More Sustainable Manufacturing Systems written by Francisco J. G. Silva and published by Springer Nature. This book was released on 2023-08-24 with total page 1237 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reports on cutting-edge research and developments in manufacturing, giving a special emphasis to solutions fostering automation, sustainability and health, safety and well-being at work. Topics cover manufacturing process analysis and optimization, supply chain management, quality control, as well as human factors and logistics. They highlight the role and advantages of intelligent systems and technologies, discussing current best-practices and challenges to cope with in the near future. Based on proceedings of the 32nd edition of the International Conference on Flexible Automation and Intelligent Manufacturing, FAIM 2023, held on June 18–22, 2023, in Porto, Portugal, this second volume of a 2-volume set provides academics and professionals with extensive information on innovative strategies for industrial management in the era of industry 5.0.
Download or read book An Industrial IoT Approach for Pharmaceutical Industry Growth written by Valentina Emilia Balas and published by Academic Press. This book was released on 2020-05-15 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: An Industrial IoT Approach for Pharmaceutical Industry Growth, Volume Two uses an innovative approach to explore how the Internet of Things (IoT) and big data can improve approaches and make discoveries. Rapid growth of the IoT has encouraged many companies in the manufacturing sector to make use of this technology to unlock its potential. Using clear language and real-world case studies, this book discusses systems level from both a human-factors point-of-view and the perspective of networking, databases, privacy and anti-spoofing. The wide variety in topics presented offers multiple perspectives on how to integrate the Internet of Things into pharmaceutical manufacturing. This book represents a useful resource for researchers in pharmaceutical sciences, information and communication technologies, and those who specialize in healthcare and pharmacovigilance. Emphasizes efficiency in pharmaceutical manufacturing through an IoT/Big Data approach Explores cutting-edge technologies through sensor enabled environments in the pharmaceutical industry Discusses system levels from both a human-factors point-of-view and the perspective of networking, databases, privacy and anti-spoofing
Download or read book PAT Applied in Biopharmaceutical Process Development And Manufacturing written by Cenk Undey and published by CRC Press. This book was released on 2011-12-07 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: As with all of pharmaceutical production, the regulatory environment for the production of therapeutics has been changing as a direct result of the US FDA-initiated Quality by Design (QbD) guidelines and corresponding activities of the International Committee for Harmonization (ICH). Given the rapid growth in the biopharmaceutical area and the complexity of the molecules, the optimum use of which are still being developed, there is a great need for flexible and proactive teams in order to satisfy the regulatory requirements during process development. Process Analytical Technologies (PAT) applied in biopharmaceutical process development and manufacturing have received significant attention in recent years as an enabler to the QbD paradigm. PAT Applied in Biopharmaceutical Process Development and Manufacturing covers technological advances in measurement sciences, data acquisition, monitoring, and control. Technical leaders present real-life case studies in areas including measuring and monitoring raw materials, cell culture, purification, and cleaning and lyophilization processes via advanced PAT. They also explore how data are collected and analyzed using advanced analytical techniques such as multivariate data analysis, monitoring, and control in real-time. Invaluable for experienced practitioners in PAT in biopharmaceuticals, this book is an excellent reference guide for regulatory officials and a vital training aid for students who need to learn the state of the art in this interdisciplinary and exciting area.
Download or read book Lean for the Process Industries written by Peter L. King and published by Productivity Press. This book was released on 2019 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drawing on 40 years of application experience at one of the world's largest chemical and materials manufacturers, King provides the first comprehensive resource written explicitly for change agents within the process industries.
Download or read book Recent Advances in Smart Manufacturing and Materials written by Rajeev Agrawal and published by Springer Nature. This book was released on 2021-07-22 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents select proceedings of the International Conference on Evolution in Manufacturing (ICEM 2020), and examines a range of areas including internet-of-things for cyber manufacturing, data analytics for manufacturing systems and processes and materials. The topics covered include modeling simulation and decision making in cyber physical systems for supporting engineering and production management, innovative approach in materials development, biomaterial applications, and advancement in manufacturing and material technologies. The book also discusses sustainability in manufacturing and supply chain management including circular economy. The book will be a valuable reference for beginners, researchers, and professionals interested in smart manufacturing in engineering, production management and materials technology.
