Download or read book Landscape with Mutant written by Frederick Pollack and published by . This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Poems about US life before and during the Trump presidency, with its alienation, violence, and political despair. In this dystopian landscape, the weak exist to be trodden and those who are trodden are weak.' It is a book about casual racism, sharp-suited Fascism and the complicity of liberals in the assault on equality and justice. Between the nar
Download or read book Molecular Evolution on Rugged Landscapes written by Alan S. Perelson and published by CRC Press. This book was released on 2018-03-08 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book lays out a number of the general issues concerning the structure of rugged fitness landscapes and examines both the history and the current status of experimental work on somatic mutation and the maturation of the immune response.
Download or read book Complexity Entropy And The Physics Of Information written by Wojciech H. Zurek and published by CRC Press. This book was released on 2018-03-08 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book has emerged from a meeting held during the week of May 29 to June 2, 1989, at St. John’s College in Santa Fe under the auspices of the Santa Fe Institute. The (approximately 40) official participants as well as equally numerous “groupies” were enticed to Santa Fe by the above “manifesto.” The book—like the “Complexity, Entropy and the Physics of Information” meeting explores not only the connections between quantum and classical physics, information and its transfer, computation, and their significance for the formulation of physical theories, but it also considers the origins and evolution of the information-processing entities, their complexity, and the manner in which they analyze their perceptions to form models of the Universe. As a result, the contributions can be divided into distinct sections only with some difficulty. Indeed, I regard this degree of overlapping as a measure of the success of the meeting. It signifies consensus about the important questions and on the anticipated answers: they presumably lie somewhere in the “border territory,” where information, physics, complexity, quantum, and computation all meet.
Download or read book Encyclopedia of Genetics Genomics Proteomics and Informatics written by George P. Rédei and published by Springer Science & Business Media. This book was released on 2008-04-25 with total page 2139 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new third edition updates a best-selling encyclopedia. It includes about 56% more words than the 1,392-page second edition of 2003. The number of illustrations increased to almost 2,000 and their quality has improved by design and four colors. It includes approximately 1,800 current databases and web servers. This encyclopedia covers the basics and the latest in genomics, proteomics, genetic engineering, small RNAs, transcription factories, chromosome territories, stem cells, genetic networks, epigenetics, prions, hereditary diseases, and patents. Similar integrated information is not available in textbooks or on the Internet.
Download or read book The Origins of Order written by Stuart A. Kauffman and published by Oxford University Press. This book was released on 1993-06-10 with total page 958 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stuart Kauffman here presents a brilliant new paradigm for evolutionary biology, one that extends the basic concepts of Darwinian evolution to accommodate recent findings and perspectives from the fields of biology, physics, chemistry and mathematics. The book drives to the heart of the exciting debate on the origins of life and maintenance of order in complex biological systems. It focuses on the concept of self-organization: the spontaneous emergence of order that is widely observed throughout nature Kauffman argues that self-organization plays an important role in the Darwinian process of natural selection. Yet until now no systematic effort has been made to incorporate the concept of self-organization into evolutionary theory. The construction requirements which permit complex systems to adapt are poorly understood, as is the extent to which selection itself can yield systems able to adapt more successfully. This book explores these themes. It shows how complex systems, contrary to expectations, can spontaneously exhibit stunning degrees of order, and how this order, in turn, is essential for understanding the emergence and development of life on Earth. Topics include the new biotechnology of applied molecular evolution, with its important implications for developing new drugs and vaccines; the balance between order and chaos observed in many naturally occurring systems; new insights concerning the predictive power of statistical mechanics in biology; and other major issues. Indeed, the approaches investigated here may prove to be the new center around which biological science itself will evolve. The work is written for all those interested in the cutting edge of research in the life sciences.
Download or read book Annual Reports in Combinatorial Chemistry and Molecular Diversity written by W.H. Moos and published by Springer Science & Business Media. This book was released on 1997-04-30 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Combinatorial chemistry and molecular diversity approaches to scientific inquiry and novel product R&D have exploded in the 1990s! For example, in the preparation of drug candidates, the automated, permutational, and combinatorial use of chemical building blocks now allows the generation and screening of unprecedented numbers of compounds. Drug discovery - better, faster, cheaper? Indeed, more compounds have been made and screened in the 1990s than in the last hundred years of pharmaceutical research. This first volume covers: (i) combinatorial chemistry, (ii) combinatorial biology and evolution, and (iii) informatics and related topics. Within each section chapters are prepared by experts in the field, including, for example, in Section I: Coverage of mixture pools vs. parallel individual compound synthesis, solution vs. solid-phase synthesis, analytical tools, and automation. Section II highlights selection strategies and library-based evolution, phage display, peptide and nucleic acid libraries. Section III covers databases and library design, high through-put screening, coding strategies vs. deconvolutions, intellectual property issues, deals and collaborations, and successes to date.
Download or read book Understanding Origins written by Francisco J. Varela and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: The main intention of this book is to bring together contributions from biology, cognitive science, and the humanities for a joint exploration of some of the main contemporary notions dealing with the understanding of origins in life,mind and society. The question of origin is inseparable from a web of hypotheses that both shape and explain us. Although origin invites examination, it always seems to elude our grasp. Notions have always been produced to interpret the genesis of life, mind, and the social order, and these notions have all remained unstable in the face of theoretical and empirical challenges. In any given period, the central ideas on origin have had a mutual resonance frequently overlooked by specialists engaged in theirown particular fields. As a consequence, this book should be of interest to a wide audi ence. In particular, for all those engaged in the social sciences and the philosophy of science, it is unique document, since bridges to the natural sciences in a mutually illuminating way are hard to find. Whether as a primary source or as inspirational reading, we feel this book has a place in every library. The material comes from an international meeting held in September 13-16, 1987 at Stanford University, organized by F. Varela and J.-P. Dupuy at the request of the Program of Interdisciplinary Research of Stanford University. We are grateful to Rene Girard, the Program Director, for making it possible with the help of the Mellon Foundation.
Download or read book Precision Molecular Pathology of Glioblastoma written by José Javier Otero and published by Springer Nature. This book was released on 2021-04-30 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a balanced and realistic review of the current state of glioblastoma, ranging from traditional histological review, molecular pathology of glioma, modern radiomics, neurosurgical focus, and integration of treatment plans by neuro-oncologists. The book reviews basic principles such as epidemiology and etiology, and modern 2016 WHO classification of CNS tumors. Chapters cover a general overview of common molecular techniques used in molecular pathology, molecular pathology in a developing country, key drivers of patient outcomes and predictors of response to radiation and/or chemotherapy treatment, and immunohistochemical surrogates for key molecular pathology. It concludes with reviews on radiomics, animal and stem cell models of glioblastoma, and a chapter on the emerging field of Glioblastoma Neuroscience. Precision Molecular Pathology of Glioblastoma is intended for pathology residents and fellows interested in glioblastoma, general surgical pathologists who need reviews on how to implement modern glioblastoma classification, as well as neuro-radiologists, oncologists, and radiation oncologists needing a holistic perspective to glioblastoma diagnosis and management.
Download or read book Recent Advances in the Theory and Application of Fitness Landscapes written by Hendrik Richter and published by Springer Science & Business Media. This book was released on 2013-11-19 with total page 577 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is concerned with recent advances in fitness landscapes. The concept of fitness landscapes originates from theoretical biology and refers to a framework for analysing and visualizing the relationships between genotypes, phenotypes and fitness. These relationships lay at the centre of attempts to mathematically describe evolutionary processes and evolutionary dynamics. The book addresses recent advances in the understanding of fitness landscapes in evolutionary biology and evolutionary computation. In the volume, experts in the field of fitness landscapes present these findings in an integrated way to make it accessible to a number of audiences: senior undergraduate and graduate students in computer science, theoretical biology, physics, applied mathematics and engineering, but also researcher looking for a reference or/and entry point into using fitness landscapes for analysing algorithms. Also practitioners wanting to employ fitness landscape techniques for evaluating bio- and nature-inspired computing algorithms can find valuable material in the book. For teaching proposes, the book could also be used as a reference handbook.
Download or read book Thinking About Biology written by Wilfred Stein and published by CRC Press. This book was released on 2018-03-08 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the emergence of life, the development of the individual, and the study of the interaction between individuals and species. It gives the student of theoretical biology some idea of the flavor of current research in the field.
Download or read book Genetic and Evolutionary Computation GECCO 2003 written by Erick Cantú-Paz and published by Springer Science & Business Media. This book was released on 2003-06-30 with total page 1317 pages. Available in PDF, EPUB and Kindle. Book excerpt: The set LNCS 2723 and LNCS 2724 constitutes the refereed proceedings of the Genetic and Evolutionary Computation Conference, GECCO 2003, held in Chicago, IL, USA in July 2003. The 193 revised full papers and 93 poster papers presented were carefully reviewed and selected from a total of 417 submissions. The papers are organized in topical sections on a-life adaptive behavior, agents, and ant colony optimization; artificial immune systems; coevolution; DNA, molecular, and quantum computing; evolvable hardware; evolutionary robotics; evolution strategies and evolutionary programming; evolutionary sheduling routing; genetic algorithms; genetic programming; learning classifier systems; real-world applications; and search based software engineering.
Download or read book Theoretical Models in Biology written by Glenn Rowe and published by Oxford University Press. This book was released on 1994 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book surveys the state of the art in theoretical and computer modeling for biological sciences. Using both mathematical and stochastic computer models of biological systems, the author focuses in particular on three central topics: the origin of life, the immune system, and memory in the brain. Throughout the book, the author emphasizes how the power of modern computers is allowing researchers in theoretical biology to break free of the constraints on modeling that were imposed by the traditional differential equation approach. Unique in its emphasis on modeling and computer simulation, Theoretical Models in Biology: The Origin of Life, the Immune System, and the Brain will be welcomed by students and researchers of mathematical biology.
Download or read book Theoretical Immunology Part One written by Alan S. Perelson and published by CRC Press. This book was released on 2018-03-05 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: Assuming that the complex phenomena underlying the operation of the immune system may be better understood through the collaborative efforts of theorists and experimentalists viewing the same phenomena in different ways, the Sante Fe Institute and the Theoretical Division of Los Alamos National Laboratory cosponsored a workshop entitled "Theoretical Immunology". The workshop focused on themes spanning the field of immunology, with emphasis on areas where the theorists have made the most progress. This book covers the discussions a that workshop on the topics of immune surveillance, mathematical models of HIV infection, complexities of antigen-antibody systems, immune suppression and tolerance, and idiotypie networks. In each of these areas there is reason to believe that advances can be made either through interactions among experimentalists and theorists or through the critical look experimentalists and theorists will bring to bear upon one another's work.
Download or read book Evolutionary Approaches to Protein Design written by and published by Elsevier. This book was released on 2000-10-19 with total page 451 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first high-quality, comprehensive overview of the field of evolutionary protein design. Topics include new protein design strategies, the structures of laboratory-evolved proteins, the evolution of non-natural enzyme functions, and the theory of laboratory evolution.
Download or read book Algebraic and Discrete Mathematical Methods for Modern Biology written by Raina Robeva and published by Academic Press. This book was released on 2015-05-09 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by experts in both mathematics and biology, Algebraic and Discrete Mathematical Methods for Modern Biology offers a bridge between math and biology, providing a framework for simulating, analyzing, predicting, and modulating the behavior of complex biological systems. Each chapter begins with a question from modern biology, followed by the description of certain mathematical methods and theory appropriate in the search of answers. Every topic provides a fast-track pathway through the problem by presenting the biological foundation, covering the relevant mathematical theory, and highlighting connections between them. Many of the projects and exercises embedded in each chapter utilize specialized software, providing students with much-needed familiarity and experience with computing applications, critical components of the "modern biology" skill set. This book is appropriate for mathematics courses such as finite mathematics, discrete structures, linear algebra, abstract/modern algebra, graph theory, probability, bioinformatics, statistics, biostatistics, and modeling, as well as for biology courses such as genetics, cell and molecular biology, biochemistry, ecology, and evolution. - Examines significant questions in modern biology and their mathematical treatments - Presents important mathematical concepts and tools in the context of essential biology - Features material of interest to students in both mathematics and biology - Presents chapters in modular format so coverage need not follow the Table of Contents - Introduces projects appropriate for undergraduate research - Utilizes freely accessible software for visualization, simulation, and analysis in modern biology - Requires no calculus as a prerequisite - Provides a complete Solutions Manual - Features a companion website with supplementary resources
Download or read book Foundations of Genetic Algorithms written by Colin R. Reeves and published by Morgan Kaufmann. This book was released on 1999 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Consists of conference papers from the Foundations of Genetic Algorithms workshop.
Download or read book Spin Glasses And Biology written by Daniel L Stein and published by World Scientific. This book was released on 1992-08-11 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is an introduction to the application of techniques developed for the study of disordered systems to problems which arise in biology. Topics presented include neural networks, adaptation and evolution, maturation of the immune response, and protein dynamics and folding. This book will appeal to students and researchers interested in statistical and condensed matter physics, glasses and spin glasses, and biophysics.
