Download or read book Mesenchymal Stem Cell Therapy written by Lucas G. Chase and published by Springer Science & Business Media. This book was released on 2012-12-12 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decade, significant efforts have been made to develop stem cell-based therapies for difficult to treat diseases. Multipotent mesenchymal stromal cells, also referred to as mesenchymal stem cells (MSCs), appear to hold great promise in regards to a regenerative cell-based therapy for the treatment of these diseases. Currently, more than 200 clinical trials are underway worldwide exploring the use of MSCs for the treatment of a wide range of disorders including bone, cartilage and tendon damage, myocardial infarction, graft-versus-host disease, Crohn’s disease, diabetes, multiple sclerosis, critical limb ischemia and many others. MSCs were first identified by Friendenstein and colleagues as an adherent stromal cell population within the bone marrow with the ability to form clonogenic colonies in vitro. In regards to the basic biology associated with MSCs, there has been tremendous progress towards understanding this cell population’s phenotype and function from a range of tissue sources. Despite enormous progress and an overall increased understanding of MSCs at the molecular and cellular level, several critical questions remain to be answered in regards to the use of these cells in therapeutic applications. Clinically, both autologous and allogenic approaches for the transplantation of MSCs are being explored. Several of the processing steps needed for the clinical application of MSCs, including isolation from various tissues, scalable in vitro expansion, cell banking, dose preparation, quality control parameters, delivery methods and numerous others are being extensively studied. Despite a significant number of ongoing clinical trials, none of the current therapeutic approaches have, at this point, become a standard of care treatment. Although exceptionally promising, the clinical translation of MSC-based therapies is still a work in progress. The extensive number of ongoing clinical trials is expected to provide a clearer path forward for the realization and implementation of MSCs in regenerative medicine. Towards this end, reviews of current clinical trial results and discussions of relevant topics association with the clinical application of MSCs are compiled in this book from some of the leading researchers in this exciting and rapidly advancing field. Although not absolutely all-inclusive, we hope the chapters within this book can promote and enable a better understanding of the translation of MSCs from bench-to-bedside and inspire researchers to further explore this promising and quickly evolving field.

Download or read book Forms of Modernity written by Rachel Lynn Schmidt and published by University of Toronto Press. This book was released on 2011-01-01 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: It's a critical cliché that Cervantes' Don Quixote is the first modern novel, but this distinction raises two fundamental questions. First, how does one define a novel? And second, what is the relationship between this genre and understandings of modernity? In Forms of Modernity, Rachel Schmidt examines how seminal theorists and philosophers have wrestled with the status of Cervantes' masterpiece as an 'exemplary novel', in turn contributing to the emergence of key concepts within genre theory. Schmidt's discussion covers the views of well-known thinkers such as Friedrich Schlegel, José Ortega y Gasset, and Mikhail Bakhtin, but also the pivotal contributions of philosophers such as Hermann Cohen and Miguel de Unamuno. These theorists' examinations of Cervantes's fictional knight errant character point to an ever-shifting boundary between the real and the virtual. Drawing from both intellectual and literary history, Forms of Modernity richly explores the development of the categories and theories that we use today to analyze and understand novels.

Download or read book A Critical Revision of the Genus Aristida written by Jan Theodoor Henrard and published by . This book was released on 1926 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Nature and History in Modern Italy written by Marco Armiero and published by Ohio University Press. This book was released on 2010-08-31 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt: Marco Armiero is Senior Researcher at the Italian National Research Council and Marie Curie Fellow at the Institute of Environmental Sciences and Technologies, Universitat Aut(noma de Barcelona. He has published extensively on-Italian environmental history and edited Views from the South: Environmental Stories from the Mediterranean World. --

Download or read book Basic and Clinical Pharmacology written by Bertram G. Katzung and published by . This book was released on 2001 with total page 1217 pages. Available in PDF, EPUB and Kindle. Book excerpt: This best selling book delivers the most current, complete, and authoritative pharmacology information to students and practitioners. All sections are updated with new drug information and references. New! Many new figures and diagrams, along with boxes of highlighted material explaining the "how and why" behind the facts.

Download or read book NANDA International Nursing Diagnoses written by Heather T. Herdman and published by Thieme. This book was released on 2017-06-28 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fully updated and revised by authors T. Heather Herdman, PhD, RN, FNI, and Shigemi Kamitsuru, PhD, RN, FNI, Nursing Diagnoses: Definitions and Classification 2018-2020, Eleventh Edition is the definitive guide to nursing diagnoses, as reviewed and approved by NANDA International (NANDA-I). In this new edition of a seminal text, the authors have written all introductory chapters at an undergraduate nursing level, providing the critical information needed for nurses to understand assessment, its link to diagnosis and clinical reasoning, and the purpose and use of taxonomic structure for the nurse at the bedside. Other changes include: 18 new nursing diagnoses and 72 revised diagnoses Updates to 11 nursing diagnosis labels, ensuring they are consistent with current literature and reflect a human response Modifications to the vast majority of the nursing diagnosis definitions, including especially Risk Diagnoses Standardization of diagnostic indicator terms (defining characteristics, related factors, risk factors, associated conditions, and at-risk populations) to further aid clarity for readers and clinicians Coding of all diagnostic indicator terms for those using electronic versions of the terminology Web-based resources include chapter and reference lists for new diagnoses Rigorously updated and revised, Nursing Diagnoses: Definitions and Classification 2018-2020, Eleventh Edition is a must-have resource for all nursing students, professional nurses, nurse educators, nurse informaticists, and nurse administrators.

Download or read book The Protective Arm of the Renin Angiotensin System RAS written by Thomas Unger and published by Academic Press. This book was released on 2015-04-18 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Protective Arm of the Renin Angiotensin System: Functional Aspects and Therapeutic Implications is the first comprehensive publication to signal the protective role of a distinct part of the renin–angiotensin system (RAS), providing readers with early insight into a complex system which will become of major medical importance in the near future. Focusing on recent research, The Protective Arm of the Renin Angiotensin System presents a host of new experimental studies on specific components of the RAS, namely angiotensin AT2 receptors (AT2R), the angiotensin (1–7) peptide with its receptor Mas, and the enzyme ACE 2, which exert significant beneficial, health-promoting actions by counterbalancing the well-known harmful arm of the RAS with its classical angiotensin AT1 receptor. This innovative concept of the protective arm of the RAS, examined in this reference, represents an indispensable background and will be a strong support for biomedical students, researchers, cardiologists, surgeons, nephrologists, diabetologists, and endocrinologists, as well as any other physician or researcher concerned with RAS physiology, pathophysiology and clinical implications. Provides a complete understanding of the protective side of the Renin Angiotensin System (RAS) involving angiotensin AT2 receptor, ACE2, and Ang(1-7)/Mas receptor Combines the knowledge of editors who pioneered research on the protective renin angiotensin system including; Dr. Thomas Unger, one of the founders of AT2 receptor research; Dr. Ulrike M. Steckelings, who contributed significantly to first preclinical studies with a novel specific AT2-agonist, and Dr. Robson Santos who pioneered research on angiotensin-(1-7) and its receptor Mas. Shows that the protective RAS axes are able to ameliorate the course of several cardiovascular, renal, metabolic and neurological diseases Provides the basis for the understanding of a novel therapeutic approach to stimulate components of the protective arm of the RAS.

Download or read book Control of Chagas Disease written by World Health Organization and published by World Health Organization. This book was released on 2002-05 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report of a WHO Expert Committee reviews current knowledge of Chagas disease and its pathogenesis discusses the causative parasite the triatomine vectors and the natural reservoirs of infection and considers the epidemiology and incidence trends of the disease. Prevention and control strategies are described as are the various formal initiatives for interruption of disease transmission. The report concludes by identifying priorities for research and offering guidance for the planning implementation and strengthening of national control programmes. ... this book makes an extremely valuable contribution toward understanding Chagas disease and promoting solid prevention and control efforts. It will no doubt be an important addition to the library of anyone student and expert alike with interests in Chagas disease. The authors are to be congratulated on the completion of a work of excellence - an extremely difficult endeavour at a time when our knowledge of vectors parasites and methodologies is expanding so rapidly. - Transactions of the Royal Society of Tropical Medicine and Hygiene

Download or read book Embryonic and Adult Stem Cells written by Margaret Haerens and published by Greenhaven Publishing. This book was released on 2009 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Science sought answers to the ethics of animal testing, and testing in humans, and once such answer was stem cells. They propose a whole new way of solving what ails us. Along with this new technology came a scathing ethical, moral, and political debate. Present your students with this thorough examination, that provides two sides to every issue. Essays debate whether it is immoral, whether government policies are contradictory, whether research should be federally funded, which stem cells are most valuable, and the role that embryonic stem cells should play.

Download or read book Petroleum and Tectonics in Mobile Belts written by Institut français du pétrole and published by Editions TECHNIP. This book was released on 1990 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Parenthood written by Rebecca S. Cohen and published by Guilford Press. This book was released on 1984-04-23 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Cognition and Psychotherapy written by M.J. Mahoney and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: For almost three millennia, philosophy and its more pragmatic offspring, psychology and the cognitive sciences, have struggled to understand the complex principles reflected in the patterned opera tions of the human mind. What is knowledge? How does it relate to what we feel and do? What are the fundamental processes underlying attention, perception, intention, learning, memory, and conscious ness? How are thought, feeling, and action related, and what are the practical implications of our current knowledge for the everyday priorities of parenting, education, and counseling? Such meaningful and fascinating questions lie at the heart of contemporary attempts to build a stronger working alliance among the fields of epistemology (theories of knowledge), the cognitive sciences, and psychotherapy. The proliferation and pervasiveness of what some have called "cognitivism" throughout all quarters of modern psychology repre sent a phenomenon of paradigmatic proportions. The (re-)emergence of cognitive concepts and perspectives-whether portrayed as revo lutionary (reactive) or evolutionary (developmental) in nature-marks what may well be the single most formative theme in late twentieth century psychology. Skeptics of the cognitive movement, if it may be so called, can readily note the necessary limits and liabilities of naive forms of metaphysics and mentalism. The history of human ideas is writ large in the polarities of "in here" and "out there"-from Plato, Pythagoras, and Kant to Locke, Bacon, and Watson.

Download or read book The Periplus of Hanno written by Hanno and published by . This book was released on 1913 with total page 94 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The New Century Italian Renaissance Encyclopedia written by Catherine B. Avery and published by . This book was released on 1972 with total page 1076 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Coronavirus Covid 19 Tax Relief Law Explanation Analysis written by Cch Tax Law and published by . This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the publication of Coronavirus (COVID-19) Tax Relief: Law, Explanation & Analysis, Wolters Kluwer is providing practitioners with a single integrated source for law and explanation of the tax provisions of the Families First Coronavirus Response Act and the Coronavirus Aid, Relief, and Economic Security (CARES) Act as well as other important guidance issued by the IRS. This volume includes the text of amended sections of the Internal Revenue Code, Congressional reports, and detailed explanations, complete with analysis and practitioner comments covering the tax provisions of these two massive Acts.

Download or read book Synopsis of the Australian Emesinae written by Pedro W Wygodzinsky and published by . This book was released on 2012-03-01 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt: Additional Editors Include E. A. Steinhaus And R. L. Usinger. University Of California Publications In Entomology, V11, No. 4.

Download or read book Critical Qualitative Inquiry written by Gaile S Cannella and published by Routledge. This book was released on 2016-07-01 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: Critical approaches to qualitative research have made a significant impact on research practice over the past decade. This comprehensive volume of contemporary, original articles places this trend in its historical context, describes the current landscape of critical work, and considers the future of this turn. The book-includes contributions from some of the leading qualitative researchers on three continents;-consists of big-picture articles that describe the dimensions of this research tradition;-situates critical qualitative inquiry in the overall development and landscape of qualitative research.