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Download or read book Encyclopedia of Biopharmaceutical Statistics Four Volume Set written by Shein-Chung Chow and published by CRC Press. This book was released on 2018-09-03 with total page 2434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the publication of the first edition in 2000, there has been an explosive growth of literature in biopharmaceutical research and development of new medicines. This encyclopedia (1) provides a comprehensive and unified presentation of designs and analyses used at different stages of the drug development process, (2) gives a well-balanced summary of current regulatory requirements, and (3) describes recently developed statistical methods in the pharmaceutical sciences. Features of the Fourth Edition: 1. 78 new and revised entries have been added for a total of 308 chapters and a fourth volume has been added to encompass the increased number of chapters. 2. Revised and updated entries reflect changes and recent developments in regulatory requirements for the drug review/approval process and statistical designs and methodologies. 3. Additional topics include multiple-stage adaptive trial design in clinical research, translational medicine, design and analysis of biosimilar drug development, big data analytics, and real world evidence for clinical research and development. 4. A table of contents organized by stages of biopharmaceutical development provides easy access to relevant topics. About the Editor: Shein-Chung Chow, Ph.D. is currently an Associate Director, Office of Biostatistics, U.S. Food and Drug Administration (FDA). Dr. Chow is an Adjunct Professor at Duke University School of Medicine, as well as Adjunct Professor at Duke-NUS, Singapore and North Carolina State University. Dr. Chow is the Editor-in-Chief of the Journal of Biopharmaceutical Statistics and the Chapman & Hall/CRC Biostatistics Book Series and the author of 28 books and over 300 methodology papers. He was elected Fellow of the American Statistical Association in 1995.
Download or read book Fundamentals of Fluid Film Lubrication written by Bernard J. Hamrock and published by CRC Press. This book was released on 2004-03-15 with total page 747 pages. Available in PDF, EPUB and Kindle. Book excerpt: Specifically focusing on fluid film, hydrodynamic, and elastohydrodynamic lubrication, this edition studies the most important principles of fluid film lubrication for the correct design of bearings, gears, and rolling operations, and for the prevention of friction and wear in engineering designs. It explains various theories, procedures, and equations for improved solutions to machining challenges. Providing more than 1120 display equations and an introductory section in each chapter, Fundamentals of Fluid Film Lubrication, Second Edition facilitates the analysis of any machine element that uses fluid film lubrication and strengthens understanding of critical design concepts.
Download or read book Biology and Breeding of Food Legumes written by Aditya Pratap and published by CABI. This book was released on 2011 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Food legumes are important constituents of the human diet and animal feed where they are crucial to a balanced diet, supplying high quality proteins. These crops also play an important role in low-input agricultural production systems by fixing atmospheric nitrogen. Despite systematic and continuous breeding efforts through conventional methods, substantial genetic gains have not been achieved. With the rise in demand for food legumes/pulses and increased market value of these crops, research has focused on increasing production and improving the quality of pulses for both edible and industrial purposes. "Biology and Breeding of Food Legumes" covers the history, origin and evolution, botany, breeding objectives and procedures, nutritional improvement, industrial uses and post-harvest technology and also recent developments made through biotechnological intervention.
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Download or read book Acute Promyelitic Leukemia written by Pier Paolo Pandolfi and published by Springer Science & Business Media. This book was released on 2007-02-02 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past 10 years, work on acute promyelocytic leukemia (APL) has become the paradigm of translational research that began with the discovery of a recurrent chromosomal translocation, followed by the identification of the genes and proteins involved, finding their molecular functions in transcriptional control, establishing mouse models and culminating in the development of targeted therapy.
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Download or read book Neoplastic Diseases of the Blood written by Peter H. Wiernik and published by Springer Science & Business Media. This book was released on 2012-09-22 with total page 1410 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neoplastic Diseases of the Blood integrates the history, epidemiology, pathology, pathophysiology, and therapeutics of modern neoplastic hematopathology. The book is divided into five major sections, with the first four covering the spectrum of hematologic neoplasia— Chronic Leukemias and Related Disorders , Acute Leukemias, Myeloma and Related Disorders, and Lymphomas. The fifth section covers a variety of topics in supportive care. Now in its fifth edition, this classic and invaluable text brings together a team of internationally renowned experts and offers in-depth coverage of the complex interface between diagnosis and therapy. Chapters feature an accessible and easy-to-read layout and provide updates on the tremendous progress made in the last decade in the understanding of the nature of hematologic malignancies and their treatment. An authoritative and indispensable resource for students, trainees, and clinicians, this fifth edition is sure to distinguish itself as the definitive reference on this topic.
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Download or read book Textbook of Assisted Reproductive Techniques written by David K. Gardner and published by CRC Press. This book was released on 2017-11-09 with total page 1040 pages. Available in PDF, EPUB and Kindle. Book excerpt: Already established as a classic comprehensive reference for the whole team at the IVF clinic, this new edition has been extensively revised, with the addition of several important new contributions on laboratory ( including advanced sperm selection techniques for ICSI, human embryo biopsy procedures, oocyte activation, managing an oocyte bank, artificial gametes, and epigenetics) as well as on clinical topics (including GnRH agonist triggering, segmentation of IVF treatment, uterus transplantation, and risk and safety management). As previously, methods, protocols, and techniques of choice are presented by eminent contributors internationally.
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Download or read book The Nuclear Receptor FactsBook written by Vincent Laudet and published by Gulf Professional Publishing. This book was released on 2002 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt: The FactsBook Series has established itself as the best source of easily accessible and accurate facts about protein groups. They use an easy-to-follow format and are researched and compiled by experts in the field. This Factsbook is devoted to nuclear receptors. The first section presents an introduction and describes the mode of action of the receptors in general. The second section of the book contains detailed entries covering each type of receptor. Entries provide information on: Nomenclature and structure, Isolation, DNA binding properties, Ligands, Expression, Target genes, Knockouts, Disease association, Gene structure, promoter and isoforms, Chromosomal location, Amino acid sequences, Key references
Download or read book Gonadotropin Releasing Hormone Receptor Signaling and Functions written by Ivana Bjelobaba and published by Frontiers Media SA. This book was released on 2018-05-10 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook provides a comprehensive overview of our current knowledge on Gonadotropin-releasing hormone receptor evolution, structure, signaling and functions. Apart from review articles, it comprises exciting new research, as well as hypotheses and perspectives, all of which are valuable in guiding our further research in this field.
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Download or read book Hormones Brain and Behavior written by and published by Academic Press. This book was released on 2016-11-09 with total page 2494 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hormones, Brain and Behavior, Third Edition offers a state-of-the-art overview of hormonally-mediated behaviors, including an extensive discussion of the effects of hormones on insects, fish, amphibians, birds, rodents, and humans. Entries have been carefully designed to provide a valuable source of information for students and researchers in neuroendocrinology and those working in related areas, such as biology, psychology, psychiatry, and neurology. This third edition has been substantially restructured to include both foundational information and recent developments in the field. Continuing the emphasis on interdisciplinary research and practical applications, the book includes articles aligned in five main subject sections, with new chapters included on genetic and genomic techniques and clinical investigations. This reference provides unique treatment of all major vertebrate and invertebrate model systems with excellent opportunities for relating behavior to molecular genetics. The topics cover an unusual breadth (from molecules to ecophysiology), ranging from basic science to clinical research, making this reference of interest to a broad range of scientists in a variety of fields. Comprehensive and updated coverage of a rapidly growing field of research Unique treatment of all major vertebrate and invertebrate model systems with excellent opportunities for relating behavior to molecular genetics Covers an unusual breadth of topics and subject fields, ranging from molecules to ecophysiology, and from basic science to clinical research Ideal resource for interdisciplinary learning and understanding in the fields of hormones and behavior
Download or read book Giant Metallic Deposits written by Peter Laznicka and published by Springer Science & Business Media. This book was released on 2006-06-18 with total page 737 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first comprehensive book on the geological characteristics of giant metallic deposits that provides solid facts rather than rapidly changing theories. The book provides abundant material for comparative research in metallogeny, practical information for the explorationists as to where to look for the "elephants", and inspiration for commodity investors.
Download or read book Blood written by Robert I. Handin and published by Lippincott Williams & Wilkins. This book was released on 2003 with total page 2358 pages. Available in PDF, EPUB and Kindle. Book excerpt: Following its highly successful and well-respected first edition, this thoroughly revised edition offers much more! Edited and authored by leading authorities in hematology, this scientific reference textbook now comes with a CD-ROM. Additional features include some of the more salient standard and current therapeutics and an easily accessible appendix that provides great reference. The CD-ROM contains 100 of the most critical illustrations from the text—great for quick consultation from your computer.